Q9P206 (K1522_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein KIAA1522

Gene names

Name:

KIAA1522

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1035 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence caution

The sequence BAA96046.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing Polymorphism
PTM	Lipoprotein Myristate Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q9P206-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q9P206-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-19: MVVFVGRRLPALLGLFKKK → MAARAPPAAP...KAKRAKGKGR

Isoform 3 (identifier: Q9P206-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-19: MVVFVGRRLPALLGLFKKK → MGNSHHKRKAPSGPRVRSFWRFGRSAKRPA

Note: Myristoylated at Gly-2.

Isoform 4 (identifier: Q9P206-4)

The sequence of this isoform differs from the canonical sequence as follows:
     137-1028: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1035	1035	Uncharacterized protein KIAA1522		PRO_0000311246
Regions
	Compositional bias	154 – 160	7	Poly-Arg
	Compositional bias	319 – 431	113	Ser-rich
	Compositional bias	438 – 997	560	Pro-rich
Amino acid modifications
	Modified residue	110	1	Phosphoserine By similarity
	Modified residue	145	1	Phosphoserine Ref.12
	Modified residue	215	1	Phosphoserine Ref.9 Ref.10
	Modified residue	339	1	Phosphoserine Ref.7
	Modified residue	342	1	Phosphoserine Ref.7 Ref.12
	Modified residue	404	1	Phosphoserine By similarity
	Modified residue	447	1	Phosphoserine By similarity
	Modified residue	545	1	Phosphoserine Ref.7 Ref.12 Ref.13
	Modified residue	593	1	Phosphothreonine Ref.9
	Modified residue	669	1	Phosphoserine Ref.9 Ref.13
	Modified residue	673	1	Phosphoserine Ref.9
	Modified residue	858	1	Phosphoserine Ref.9 Ref.12
	Modified residue	862	1	Phosphoserine Ref.9 Ref.12
	Modified residue	868	1	Phosphoserine Ref.12
	Modified residue	906	1	Phosphoserine By similarity
	Modified residue	929	1	Phosphoserine Ref.8 Ref.9 Ref.12
	Modified residue	971	1	Phosphoserine Ref.9 Ref.13
	Modified residue	979	1	Phosphoserine Ref.9 Ref.12 Ref.13
	Modified residue	981	1	Phosphoserine By similarity
Natural variations
	Alternative sequence	1 – 19	19	MVVFV…LFKKK → MAARAPPAAPAAEEPGNPGG PPRRKKSRSGASGLRRAFSW LRGKRRKKKAAGAEGAEPAA PRAKKAEDKAKRAKGKGR in isoform 2.		VSP_040217
	Alternative sequence	1 – 19	19	MVVFV…LFKKK → MGNSHHKRKAPSGPRVRSFW RFGRSAKRPA in isoform 3.		VSP_041634
	Alternative sequence	137 – 1028	892	Missing in isoform 4.		VSP_043215
	Natural variant	57	1	P → S. Corresponds to variant rs11803515 [ dbSNP | Ensembl ].		VAR_037190
	Natural variant	114	1	S → P. Corresponds to variant rs3737994 [ dbSNP | Ensembl ].		VAR_037191
	Natural variant	232	1	M → V. Corresponds to variant rs12730560 [ dbSNP | Ensembl ].		VAR_037192
	Natural variant	310	1	L → I. Corresponds to variant rs11582639 [ dbSNP | Ensembl ].		VAR_037193
	Natural variant	770	1	P → L. Corresponds to variant rs581875 [ dbSNP | Ensembl ].		VAR_037194
	Natural variant	1021	1	E → K. Corresponds to variant rs675928 [ dbSNP | Ensembl ].		VAR_037195

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified November 13, 2007. Version 2. Checksum: CE674245F15108CE	FASTA	1,035	107,095
	10 20 30 40 50 60 MVVFVGRRLP ALLGLFKKKG SAKAENDKHL SVGPGQGPGS AVDEHQDNVF FPSGRPPHLE 70 80 90 100 110 120 ELHTQAQEGL RSLQHQEKQK LNKGGWDHGD TQSIQSSRTG PDEDNISFCS QTTSYVAESS 130 140 150 160 170 180 TAEDALSIRS EMIQRKGSTF RPHDSFPKSG KSGRRRRERR STVLGLPQHV QKELGLRNER 190 200 210 220 230 240 EAPGTPRAPG ARDAVRIPTV DGRPRGTSGM GARVSLQALE AEAEAGAETE AMLQRHIDRV 250 260 270 280 290 300 YRDDTFVGRS TGTRAPPLTR PMSLAVPGLT GGAGPAEPLS PAMSISPQAT YLSKLIPHAV 310 320 330 340 350 360 LPPTVDVVAL GRCSLRTLSR CSLHSASPAS VRSLGRFSSV SSPQPRSRHP SSSSDTWSHS 370 380 390 400 410 420 QSSDTIVSDG STLSSKGGSE GQPESSTASN SVVPPPQGGS GRGSPSGGST AEASDTLSIR 430 440 450 460 470 480 SSGQLSGRSV SLRKLKRPPP PPRRTHSLHQ RGLAVPDGPL GLPPKPERKQ QPQLPRPPTT 490 500 510 520 530 540 GGSEGAGAAP CPPNPANSWV PGLSPGGSRR PPRSPERTLS PSSGYSSQSG TPTLPPKGLA 550 560 570 580 590 600 GPPASPGKAQ PPKPERVTSL RSPGASVSSS LTSLCSSSSD PAPSDRSGPQ ILTPLGDRFV 610 620 630 640 650 660 IPPHPKVPAP FSPPPSKPRS PNPAAPALAA PAVVPGPVST TDASPQSPPT PQTTLTPLQE 670 680 690 700 710 720 SPVISKDQSP PPSPPPSYHP PPPPTKKPEV VVEAPSASET AEEPLQDPNW PPPPPPAPEE 730 740 750 760 770 780 QDLSMADFPP PEEAFFSVAS PEPAGPSGSP ELVSSPAASS SSATALQIQP PGSPDPPPAP 790 800 810 820 830 840 PAPAPASSAP GHVAKLPQKE PVGCSKGGGP PREDVGAPLV TPSLLQMVRL RSVGAPGGAP 850 860 870 880 890 900 TPALGPSAPQ KPLRRALSGR ASPVPAPSSG LHAAVRLKAC SLAASEGLSS AQPNGPPEAE 910 920 930 940 950 960 PRPPQSPAST ASFIFSKGSR KLQLERPVSP ETQADLQRNL VAELRSISEQ RPPQAPKKSP 970 980 990 1000 1010 1020 KAPPPVARKP SVGVPPPASP SYPRAEPLTA PPTNGLPHTQ DRTKRELAEN GGVLQLVGPE 1030 EKMGLPGSDS QKELA
	Isoform 2 [UniParc]. Checksum: 214DF1694FAB0174	FASTA	1,094	113,062
	10 20 30 40 50 60 MAARAPPAAP AAEEPGNPGG PPRRKKSRSG ASGLRRAFSW LRGKRRKKKA AGAEGAEPAA 70 80 90 100 110 120 PRAKKAEDKA KRAKGKGRGS AKAENDKHLS VGPGQGPGSA VDEHQDNVFF PSGRPPHLEE 130 140 150 160 170 180 LHTQAQEGLR SLQHQEKQKL NKGGWDHGDT QSIQSSRTGP DEDNISFCSQ TTSYVAESST 190 200 210 220 230 240 AEDALSIRSE MIQRKGSTFR PHDSFPKSGK SGRRRRERRS TVLGLPQHVQ KELGLRNERE 250 260 270 280 290 300 APGTPRAPGA RDAVRIPTVD GRPRGTSGMG ARVSLQALEA EAEAGAETEA MLQRHIDRVY 310 320 330 340 350 360 RDDTFVGRST GTRAPPLTRP MSLAVPGLTG GAGPAEPLSP AMSISPQATY LSKLIPHAVL 370 380 390 400 410 420 PPTVDVVALG RCSLRTLSRC SLHSASPASV RSLGRFSSVS SPQPRSRHPS SSSDTWSHSQ 430 440 450 460 470 480 SSDTIVSDGS TLSSKGGSEG QPESSTASNS VVPPPQGGSG RGSPSGGSTA EASDTLSIRS 490 500 510 520 530 540 SGQLSGRSVS LRKLKRPPPP PRRTHSLHQR GLAVPDGPLG LPPKPERKQQ PQLPRPPTTG 550 560 570 580 590 600 GSEGAGAAPC PPNPANSWVP GLSPGGSRRP PRSPERTLSP SSGYSSQSGT PTLPPKGLAG 610 620 630 640 650 660 PPASPGKAQP PKPERVTSLR SPGASVSSSL TSLCSSSSDP APSDRSGPQI LTPLGDRFVI 670 680 690 700 710 720 PPHPKVPAPF SPPPSKPRSP NPAAPALAAP AVVPGPVSTT DASPQSPPTP QTTLTPLQES 730 740 750 760 770 780 PVISKDQSPP PSPPPSYHPP PPPTKKPEVV VEAPSASETA EEPLQDPNWP PPPPPAPEEQ 790 800 810 820 830 840 DLSMADFPPP EEAFFSVASP EPAGPSGSPE LVSSPAASSS SATALQIQPP GSPDPPPAPP 850 860 870 880 890 900 APAPASSAPG HVAKLPQKEP VGCSKGGGPP REDVGAPLVT PSLLQMVRLR SVGAPGGAPT 910 920 930 940 950 960 PALGPSAPQK PLRRALSGRA SPVPAPSSGL HAAVRLKACS LAASEGLSSA QPNGPPEAEP 970 980 990 1000 1010 1020 RPPQSPASTA SFIFSKGSRK LQLERPVSPE TQADLQRNLV AELRSISEQR PPQAPKKSPK 1030 1040 1050 1060 1070 1080 APPPVARKPS VGVPPPASPS YPRAEPLTAP PTNGLPHTQD RTKRELAENG GVLQLVGPEE 1090 KMGLPGSDSQ KELA
	Isoform 3 [UniParc]. Checksum: A7DE212FF521F3A9	FASTA	1,046	108,385
	10 20 30 40 50 60 MGNSHHKRKA PSGPRVRSFW RFGRSAKRPA GSAKAENDKH LSVGPGQGPG SAVDEHQDNV 70 80 90 100 110 120 FFPSGRPPHL EELHTQAQEG LRSLQHQEKQ KLNKGGWDHG DTQSIQSSRT GPDEDNISFC 130 140 150 160 170 180 SQTTSYVAES STAEDALSIR SEMIQRKGST FRPHDSFPKS GKSGRRRRER RSTVLGLPQH 190 200 210 220 230 240 VQKELGLRNE REAPGTPRAP GARDAVRIPT VDGRPRGTSG MGARVSLQAL EAEAEAGAET 250 260 270 280 290 300 EAMLQRHIDR VYRDDTFVGR STGTRAPPLT RPMSLAVPGL TGGAGPAEPL SPAMSISPQA 310 320 330 340 350 360 TYLSKLIPHA VLPPTVDVVA LGRCSLRTLS RCSLHSASPA SVRSLGRFSS VSSPQPRSRH 370 380 390 400 410 420 PSSSSDTWSH SQSSDTIVSD GSTLSSKGGS EGQPESSTAS NSVVPPPQGG SGRGSPSGGS 430 440 450 460 470 480 TAEASDTLSI RSSGQLSGRS VSLRKLKRPP PPPRRTHSLH QRGLAVPDGP LGLPPKPERK 490 500 510 520 530 540 QQPQLPRPPT TGGSEGAGAA PCPPNPANSW VPGLSPGGSR RPPRSPERTL SPSSGYSSQS 550 560 570 580 590 600 GTPTLPPKGL AGPPASPGKA QPPKPERVTS LRSPGASVSS SLTSLCSSSS DPAPSDRSGP 610 620 630 640 650 660 QILTPLGDRF VIPPHPKVPA PFSPPPSKPR SPNPAAPALA APAVVPGPVS TTDASPQSPP 670 680 690 700 710 720 TPQTTLTPLQ ESPVISKDQS PPPSPPPSYH PPPPPTKKPE VVVEAPSASE TAEEPLQDPN 730 740 750 760 770 780 WPPPPPPAPE EQDLSMADFP PPEEAFFSVA SPEPAGPSGS PELVSSPAAS SSSATALQIQ 790 800 810 820 830 840 PPGSPDPPPA PPAPAPASSA PGHVAKLPQK EPVGCSKGGG PPREDVGAPL VTPSLLQMVR 850 860 870 880 890 900 LRSVGAPGGA PTPALGPSAP QKPLRRALSG RASPVPAPSS GLHAAVRLKA CSLAASEGLS 910 920 930 940 950 960 SAQPNGPPEA EPRPPQSPAS TASFIFSKGS RKLQLERPVS PETQADLQRN LVAELRSISE 970 980 990 1000 1010 1020 QRPPQAPKKS PKAPPPVARK PSVGVPPPAS PSYPRAEPLT APPTNGLPHT QDRTKRELAE 1030 1040 NGGVLQLVGP EEKMGLPGSD SQKELA
	Isoform 4 [UniParc]. Checksum: 243512E893E0151D	FASTA	143	15,682
	10 20 30 40 50 60 MVVFVGRRLP ALLGLFKKKG SAKAENDKHL SVGPGQGPGS AVDEHQDNVF FPSGRPPHLE 70 80 90 100 110 120 ELHTQAQEGL RSLQHQEKQK LNKGGWDHGD TQSIQSSRTG PDEDNISFCS QTTSYVAESS 130 140 TAEDALSIRS EMIQRKDSQK ELA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." Nagase T., Kikuno R., Ishikawa K., Hirosawa M., Ohara O. DNA Res. 7:143-150(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Brain.
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4). Tissue: Teratocarcinoma.
[3]	"The DNA sequence and biological annotation of human chromosome 1." Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R. Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-77 (ISOFORM 2).
[5]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 709-1035 (ISOFORM 1). Tissue: Mammary cancer.
[6]	"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M. Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. Tissue: Cervix carcinoma.
[7]	"A probability-based approach for high-throughput protein phosphorylation analysis and site localization." Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P. Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-339; SER-342 AND SER-545, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[8]	"Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis." Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D., Yates J.R. III J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-929, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[9]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-215; THR-593; SER-669; SER-673; SER-858; SER-862; SER-929; SER-971 AND SER-979, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[10]	"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions." Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K. Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-215, MASS SPECTROMETRY. Tissue: Leukemic T-cell.
[11]	"Strategy for comprehensive identification of human N-myristoylated proteins using an insect cell-free protein synthesis system." Suzuki T., Moriya K., Nagatoshi K., Ota Y., Ezure T., Ando E., Tsunasawa S., Utsumi T. Proteomics 10:1780-1793(2010) [PubMed] [Europe PMC] [Abstract] Cited for: MYRISTOYLATION AT GLY-2 (ISOFORM 3).
[12]	"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis." Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M. Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-145; SER-342; SER-545; SER-858; SER-862; SER-868; SER-929 AND SER-979, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[13]	"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation." Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B. Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-545; SER-669; SER-971 AND SER-979, MASS SPECTROMETRY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB040955 mRNA. Translation: BAA96046.1. Different initiation. AK298965 mRNA. Translation: BAG61060.1. AC114489 Genomic DNA. No translation available. AI587184 mRNA. No translation available. AL713671 mRNA. Translation: CAD28477.2.
IPI	IPI00001632. IPI00872465. IPI00936576.
RefSeq	NP_001185901.1. NM_001198972.1. NP_001185902.1. NM_001198973.1. NP_065939.2. NM_020888.2.
UniGene	Hs.591502.
3D structure databases
ProteinModelPortal	Q9P206.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9P206. 2 interactions.
STRING	9606.ENSP00000383851.
PTM databases
PhosphoSite	Q9P206.
Polymorphism databases
DMDM	160395559.
Proteomic databases
PaxDb	Q9P206.
PRIDE	Q9P206.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000294521; ENSP00000294521; ENSG00000162522. ENST00000373480; ENSP00000362579; ENSG00000162522. ENST00000373481; ENSP00000362580; ENSG00000162522. ENST00000401073; ENSP00000383851; ENSG00000162522.
GeneID	57648.
KEGG	hsa:57648.
UCSC	uc001bvu.1. human. uc001bvv.2. human. uc010ohm.1. human. uc010ohn.1. human.
Organism-specific databases
CTD	57648.
GeneCards	GC01P033207.
HGNC	HGNC:29301. KIAA1522.
HPA	HPA032050.
neXtProt	NX_Q9P206.
PharmGKB	PA142671612.
HUGE	Search...
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG76260.
HOGENOM	HOG000074189.
HOVERGEN	HBG108037.
OMA	KVPAPFS.
OrthoDB	EOG4CVG70.
Gene expression databases
Bgee	Q9P206.
CleanEx	HS_KIAA1522.
Genevestigator	Q9P206.
Family and domain databases
ProtoNet	Search...
Other
ChiTaRS	KIAA1522. human.
GenomeRNAi	57648.
NextBio	64386.

Entry information

Entry name

K1522_HUMAN

Accession

Primary (citable) accession number: Q9P206
Secondary accession number(s): B4DQU8 , B5MDY0, C9JH84, Q8TCQ0

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 13, 2007
Last sequence update:	November 13, 2007
Last modified:	May 29, 2013
This is version 72 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.