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Protein
Submitted name:

Alpha-(1,3/1,4)-fucosyltransferase

Gene

FUT3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • alpha-(1->3)-fucosyltransferase activity Source: UniProtKB

GO - Biological processi

  • L-fucose catabolic process Source: UniProtKB
  • protein glycosylation Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseUniRule annotationImported, Transferase

Protein family/group databases

CAZyiGT10. Glycosyltransferase Family 10.

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-(1,3/1,4)-fucosyltransferaseImported
Submitted name:
cDNA, FLJ94139, highly similar to Homo sapiens fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group included) (FUT3), mRNAImported
Gene namesi
Name:FUT3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Golgi apparatusGolgi stack membrane UniRule annotation; Single-pass type II membrane protein UniRule annotation

GO - Cellular componenti

  • Golgi apparatus Source: UniProtKB
  • Golgi cisterna membrane Source: UniProtKB-SubCell
  • integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatusUniRule annotation, Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiQ9P1W6.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000305603.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 170Glyco_tran_10_NInterPro annotationAdd BLAST109

Sequence similaritiesi

Belongs to the glycosyltransferase 10 family.UniRule annotation

Keywords - Domaini

TransmembraneUniRule annotation

Phylogenomic databases

eggNOGiKOG2619. Eukaryota.
ENOG410ZIMX. LUCA.
HOVERGENiHBG000274.

Family and domain databases

InterProiIPR031481. Glyco_tran_10_N.
IPR001503. Glyco_trans_10.
[Graphical view]
PfamiPF17039. Glyco_tran_10_N. 1 hit.
PF00852. Glyco_transf_10. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9P1W6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPLGAAKPQ WPWRRCLAAR LFQLLVAVCF FSYLRVSRDD ATGSPRAPSG
60 70 80 90 100
SSRQDTTPTR PTLLILLWTW PFHIPVALSR CSEMVPGTAD CHITADRKVY
110 120 130 140 150
PQADTVIVHH WDIMSNPKSR LPPSPRPQGQ RWIWFNLEPP PNCQHLEALD
160 170 180 190 200
RYFNLTMSYR SDSDIFTPYG WLEPWSGQPA HPPLNLSAKT ELVAWAVSNW
210 220 230 240 250
KPDSARVRYY QSLQAHLKVD VYGRSHKPLP KGTMMETLSR YKFYLAFENS
260 270 280 290 300
LHPDYITEKL WRNALEAWAV PVVLGPSRSN YERFLPPDAF IHVDDFQSPK
310 320 330 340 350
DLARYLQELD KDHARYLSYF RWRETLRPRS FSWALDFCKA CWKLQQESRY
360
QTVRSIAAWF T
Length:361
Mass (Da):42,160
Last modified:October 1, 2000 - v1
Checksum:i6157E6B63BC34E5E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB043998 Genomic DNA. Translation: BAA96390.1.
AK313575 mRNA. Translation: BAG36347.1.
UniGeneiHs.169238.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB043998 Genomic DNA. Translation: BAA96390.1.
AK313575 mRNA. Translation: BAG36347.1.
UniGeneiHs.169238.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000305603.

Protein family/group databases

CAZyiGT10. Glycosyltransferase Family 10.

Proteomic databases

PeptideAtlasiQ9P1W6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG2619. Eukaryota.
ENOG410ZIMX. LUCA.
HOVERGENiHBG000274.

Miscellaneous databases

ChiTaRSiFUT3. human.

Family and domain databases

InterProiIPR031481. Glyco_tran_10_N.
IPR001503. Glyco_trans_10.
[Graphical view]
PfamiPF17039. Glyco_tran_10_N. 1 hit.
PF00852. Glyco_transf_10. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9P1W6_HUMAN
AccessioniPrimary (citable) accession number: Q9P1W6
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: July 6, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.