Q9P1Q0 (VPS54_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Vacuolar protein sorting-associated protein 54

Alternative name(s):
Hepatocellular carcinoma protein 8
Tumor antigen HOM-HCC-8
Tumor antigen SLP-8p

Gene names

Name:	VPS54
Synonyms:	HCC8

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	977 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	May be involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Ref.6
Subunit structure	Component of the Golgi-associated retrograde protein (GARP) complex, also called VFT (VPS fifty-three) complex, composed of VPS51, VPS52, VPS53 and VPS54. Ref.2
Sequence similarities	Belongs to the VPS54 family.
Sequence caution	The sequence BAA92134.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Protein transport Transport
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Coiled coil
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	growth Inferred from electronic annotation. Source: Compara homeostasis of number of cells within a tissue Inferred from electronic annotation. Source: Compara musculoskeletal movement Inferred from electronic annotation. Source: Compara neurofilament cytoskeleton organization Inferred from electronic annotation. Source: Compara protein transport Inferred from electronic annotation. Source: UniProtKB-KW retrograde transport, endosome to Golgi Inferred from electronic annotation. Source: InterPro
Cellular_component	GARP complex Inferred from direct assay PubMed 19620288. Source: MGI
Complete GO annotation...

Alternative products

This entry describes 5 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q9P1Q0-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q9P1Q0-2)

The sequence of this isoform differs from the canonical sequence as follows:
     964-977: DLDLNMAEIWEQKR → IWT

Note: No experimental confirmation available.

Isoform 3 (identifier: Q9P1Q0-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-117: Missing.
     118-126: TVYQQEISQ → MLPTKNRIK
     380-415: Missing.

Note: No experimental confirmation available.

Isoform 4 (identifier: Q9P1Q0-4)

The sequence of this isoform differs from the canonical sequence as follows:
     46-57: Missing.

Isoform 5 (identifier: Q9P1Q0-5)

The sequence of this isoform differs from the canonical sequence as follows:
     1-838: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 977	977	Vacuolar protein sorting-associated protein 54		PRO_0000148731
Regions
	Coiled coil	240 – 260	21	Potential
	Coiled coil	480 – 507	28	Potential
	Coiled coil	582 – 603	22	Potential
Amino acid modifications
	Modified residue	541	1	Phosphoserine By similarity
Natural variations
	Alternative sequence	1 – 838	838	Missing in isoform 5.		VSP_013751
	Alternative sequence	1 – 117	117	Missing in isoform 3.		VSP_013752
	Alternative sequence	46 – 57	12	Missing in isoform 4.		VSP_013753
	Alternative sequence	118 – 126	9	TVYQQEISQ → MLPTKNRIK in isoform 3.		VSP_013754
	Alternative sequence	380 – 415	36	Missing in isoform 3.		VSP_013755
	Alternative sequence	964 – 977	14	DLDLN…WEQKR → IWT in isoform 2.		VSP_013756
	Natural variant	561	1	S → C. Corresponds to variant rs34015596 [ dbSNP | Ensembl ].		VAR_052944
	Natural variant	912	1	M → I. Corresponds to variant rs11558741 [ dbSNP | Ensembl ].		VAR_061983
Experimental info
	Sequence conflict	130	1	I → V in AAF37319. Ref.1
	Sequence conflict	526	1	E → K in AAF37319. Ref.1
	Sequence conflict	601	1	E → G in AAF37319. Ref.1
	Sequence conflict	643	1	E → G in AAF37319. Ref.1
	Sequence conflict	650	1	E → A in AAF37319. Ref.1
	Sequence conflict	677 – 679	3	EER → VGG in AAF37319. Ref.1
	Sequence conflict	727	1	K → E in BAA92134. Ref.5
	Sequence conflict	844	1	D → G in AAH41868. Ref.4
	Sequence conflict	904	1	L → H in AAH41868. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified May 10, 2005. Version 2. Checksum: 3290160E3460C836	FASTA	977	110,589
	10 20 30 40 50 60 MASSHSSSPV PQGSSSDVFF KIEVDPSKHI RPVPSLPDVC PKEPTGDSHS LYVAPSLVTD 70 80 90 100 110 120 QHRWTVYHSK VNLPAALNDP RLAKRESDFF TKTWGLDFVD TEVIPSFYLP QISKEHFTVY 130 140 150 160 170 180 QQEISQREKI HERCKNICPP KDTFERTLLH THDKSRTDLE QVPKIFMKPD FALDDSLTFN 190 200 210 220 230 240 SVLPWSHFNT AGGKGNRDAA SSKLLQEKLS HYLDIVEVNI AHQISLRSEA FFHAMTSQHE 250 260 270 280 290 300 LQDYLRKTSQ AVKMLRDKIA QIDKVMCEGS LHILRLALTR NNCVKVYNKL KLMATVHQTQ 310 320 330 340 350 360 PTVQVLLSTS EFVGALDLIA TTQEVLQQEL QGIHSFRHLG SQLCELEKLI DKMMIAEFST 370 380 390 400 410 420 YSHSDLNRPL EDDCQVLEEE RLISLVFGLL KQRKLNFLEI YGEKMVITAK NIIKQCVINK 430 440 450 460 470 480 VSQTEEIDTD VVVKLADQMR MLNFPQWFDL LKDIFSKFTI FLQRVKATLN IIHSVVLSVL 490 500 510 520 530 540 DKNQRTRELE EISQQKNAAK DNSLDTEVAY LIHEGMFISD AFGEGELTPI AVDTTSQRNA 550 560 570 580 590 600 SPNSEPCSSD SVSEPECTTD SSSSKEHTSS SAIPGGVDIM VSEDMKLTDS ELGKLANNIQ 610 620 630 640 650 660 ELLYSASDIC HDRAVKFLMS RAKDGFLEKL NSMEFITLSR LMETFILDTE QICGRKSTSL 670 680 690 700 710 720 LGALQSQAIK FVNRFHEERK TKLSLLLDNE RWKQADVPAE FQDLVDSLSD GKIALPEKKS 730 740 750 760 770 780 GATEERKPAE VLIVEGQQYA VVGTVLLLIR IILEYCQCVD NIPSVTTDML TRLSDLLKYF 790 800 810 820 830 840 NSRSCQLVLG AGALQVVGLK TITTKNLALS SRCLQLIVHY IPVIRAHFEA RLPPKQYSML 850 860 870 880 890 900 RHFDHITKDY HDHIAEISAK LVAIMDSLFD KLLSKYEVKA PVPSACFRNI CKQMTKMHEA 910 920 930 940 950 960 IFDLLPEEQT QMLFLRINAS YKLHLKKQLS HLNVINDGGP QNGLVTADVA FYTGNLQALK 970 GLKDLDLNMA EIWEQKR
	Isoform 2 [UniParc]. Checksum: 7FA7C844A6026471	FASTA	966	109,246
	10 20 30 40 50 60 MASSHSSSPV PQGSSSDVFF KIEVDPSKHI RPVPSLPDVC PKEPTGDSHS LYVAPSLVTD 70 80 90 100 110 120 QHRWTVYHSK VNLPAALNDP RLAKRESDFF TKTWGLDFVD TEVIPSFYLP QISKEHFTVY 130 140 150 160 170 180 QQEISQREKI HERCKNICPP KDTFERTLLH THDKSRTDLE QVPKIFMKPD FALDDSLTFN 190 200 210 220 230 240 SVLPWSHFNT AGGKGNRDAA SSKLLQEKLS HYLDIVEVNI AHQISLRSEA FFHAMTSQHE 250 260 270 280 290 300 LQDYLRKTSQ AVKMLRDKIA QIDKVMCEGS LHILRLALTR NNCVKVYNKL KLMATVHQTQ 310 320 330 340 350 360 PTVQVLLSTS EFVGALDLIA TTQEVLQQEL QGIHSFRHLG SQLCELEKLI DKMMIAEFST 370 380 390 400 410 420 YSHSDLNRPL EDDCQVLEEE RLISLVFGLL KQRKLNFLEI YGEKMVITAK NIIKQCVINK 430 440 450 460 470 480 VSQTEEIDTD VVVKLADQMR MLNFPQWFDL LKDIFSKFTI FLQRVKATLN IIHSVVLSVL 490 500 510 520 530 540 DKNQRTRELE EISQQKNAAK DNSLDTEVAY LIHEGMFISD AFGEGELTPI AVDTTSQRNA 550 560 570 580 590 600 SPNSEPCSSD SVSEPECTTD SSSSKEHTSS SAIPGGVDIM VSEDMKLTDS ELGKLANNIQ 610 620 630 640 650 660 ELLYSASDIC HDRAVKFLMS RAKDGFLEKL NSMEFITLSR LMETFILDTE QICGRKSTSL 670 680 690 700 710 720 LGALQSQAIK FVNRFHEERK TKLSLLLDNE RWKQADVPAE FQDLVDSLSD GKIALPEKKS 730 740 750 760 770 780 GATEERKPAE VLIVEGQQYA VVGTVLLLIR IILEYCQCVD NIPSVTTDML TRLSDLLKYF 790 800 810 820 830 840 NSRSCQLVLG AGALQVVGLK TITTKNLALS SRCLQLIVHY IPVIRAHFEA RLPPKQYSML 850 860 870 880 890 900 RHFDHITKDY HDHIAEISAK LVAIMDSLFD KLLSKYEVKA PVPSACFRNI CKQMTKMHEA 910 920 930 940 950 960 IFDLLPEEQT QMLFLRINAS YKLHLKKQLS HLNVINDGGP QNGLVTADVA FYTGNLQALK GLKIWT
	Isoform 3 [UniParc]. Checksum: 9EF51F039A9AD46A	FASTA	824	93,274
	10 20 30 40 50 60 MLPTKNRIKR EKIHERCKNI CPPKDTFERT LLHTHDKSRT DLEQVPKIFM KPDFALDDSL 70 80 90 100 110 120 TFNSVLPWSH FNTAGGKGNR DAASSKLLQE KLSHYLDIVE VNIAHQISLR SEAFFHAMTS 130 140 150 160 170 180 QHELQDYLRK TSQAVKMLRD KIAQIDKVMC EGSLHILRLA LTRNNCVKVY NKLKLMATVH 190 200 210 220 230 240 QTQPTVQVLL STSEFVGALD LIATTQEVLQ QELQGIHSFR HLGSQLCELE KLIDKMMIAE 250 260 270 280 290 300 FSTYSHSDLN RPLEDDCQVL EECVINKVSQ TEEIDTDVVV KLADQMRMLN FPQWFDLLKD 310 320 330 340 350 360 IFSKFTIFLQ RVKATLNIIH SVVLSVLDKN QRTRELEEIS QQKNAAKDNS LDTEVAYLIH 370 380 390 400 410 420 EGMFISDAFG EGELTPIAVD TTSQRNASPN SEPCSSDSVS EPECTTDSSS SKEHTSSSAI 430 440 450 460 470 480 PGGVDIMVSE DMKLTDSELG KLANNIQELL YSASDICHDR AVKFLMSRAK DGFLEKLNSM 490 500 510 520 530 540 EFITLSRLME TFILDTEQIC GRKSTSLLGA LQSQAIKFVN RFHEERKTKL SLLLDNERWK 550 560 570 580 590 600 QADVPAEFQD LVDSLSDGKI ALPEKKSGAT EERKPAEVLI VEGQQYAVVG TVLLLIRIIL 610 620 630 640 650 660 EYCQCVDNIP SVTTDMLTRL SDLLKYFNSR SCQLVLGAGA LQVVGLKTIT TKNLALSSRC 670 680 690 700 710 720 LQLIVHYIPV IRAHFEARLP PKQYSMLRHF DHITKDYHDH IAEISAKLVA IMDSLFDKLL 730 740 750 760 770 780 SKYEVKAPVP SACFRNICKQ MTKMHEAIFD LLPEEQTQML FLRINASYKL HLKKQLSHLN 790 800 810 820 VINDGGPQNG LVTADVAFYT GNLQALKGLK DLDLNMAEIW EQKR
	Isoform 4 [UniParc]. Checksum: D91F94CD6CDC72D3	FASTA	965	109,362
	10 20 30 40 50 60 MASSHSSSPV PQGSSSDVFF KIEVDPSKHI RPVPSLPDVC PKEPTVTDQH RWTVYHSKVN 70 80 90 100 110 120 LPAALNDPRL AKRESDFFTK TWGLDFVDTE VIPSFYLPQI SKEHFTVYQQ EISQREKIHE 130 140 150 160 170 180 RCKNICPPKD TFERTLLHTH DKSRTDLEQV PKIFMKPDFA LDDSLTFNSV LPWSHFNTAG 190 200 210 220 230 240 GKGNRDAASS KLLQEKLSHY LDIVEVNIAH QISLRSEAFF HAMTSQHELQ DYLRKTSQAV 250 260 270 280 290 300 KMLRDKIAQI DKVMCEGSLH ILRLALTRNN CVKVYNKLKL MATVHQTQPT VQVLLSTSEF 310 320 330 340 350 360 VGALDLIATT QEVLQQELQG IHSFRHLGSQ LCELEKLIDK MMIAEFSTYS HSDLNRPLED 370 380 390 400 410 420 DCQVLEEERL ISLVFGLLKQ RKLNFLEIYG EKMVITAKNI IKQCVINKVS QTEEIDTDVV 430 440 450 460 470 480 VKLADQMRML NFPQWFDLLK DIFSKFTIFL QRVKATLNII HSVVLSVLDK NQRTRELEEI 490 500 510 520 530 540 SQQKNAAKDN SLDTEVAYLI HEGMFISDAF GEGELTPIAV DTTSQRNASP NSEPCSSDSV 550 560 570 580 590 600 SEPECTTDSS SSKEHTSSSA IPGGVDIMVS EDMKLTDSEL GKLANNIQEL LYSASDICHD 610 620 630 640 650 660 RAVKFLMSRA KDGFLEKLNS MEFITLSRLM ETFILDTEQI CGRKSTSLLG ALQSQAIKFV 670 680 690 700 710 720 NRFHEERKTK LSLLLDNERW KQADVPAEFQ DLVDSLSDGK IALPEKKSGA TEERKPAEVL 730 740 750 760 770 780 IVEGQQYAVV GTVLLLIRII LEYCQCVDNI PSVTTDMLTR LSDLLKYFNS RSCQLVLGAG 790 800 810 820 830 840 ALQVVGLKTI TTKNLALSSR CLQLIVHYIP VIRAHFEARL PPKQYSMLRH FDHITKDYHD 850 860 870 880 890 900 HIAEISAKLV AIMDSLFDKL LSKYEVKAPV PSACFRNICK QMTKMHEAIF DLLPEEQTQM 910 920 930 940 950 960 LFLRINASYK LHLKKQLSHL NVINDGGPQN GLVTADVAFY TGNLQALKGL KDLDLNMAEI WEQKR
	Isoform 5 [UniParc]. Checksum: F6AFBCDA077C7BB4	FASTA	139	15,982
	10 20 30 40 50 60 MLRHFDHITK DYHDHIAEIS AKLVAIMDSL FDKLLSKYEV KAPVPSACFR NICKQMTKMH 70 80 90 100 110 120 EAIFDLLPEE QTQMLFLRIN ASYKLHLKKQ LSHLNVINDG GPQNGLVTAD VAFYTGNLQA 130 LKGLKDLDLN MAEIWEQKR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"HOM-HCC-8, a novel tumor antigen associated with hepatocellular carcinoma." Stenner-Liewen F., Luo G., Tuereci O., Sahin U., Liewen H., Koslowski M., Pfreundschuh M. Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2). Tissue: Hepatoma.
[2]	"Characterization of the human GARP (Golgi associated retrograde protein) complex." Liewen H., Meinhold-Heerlein I., Oliveira V., Schwarzenbacher R., Luo G., Wadle A., Jung M., Pfreundschuh M., Stenner-Liewen F. Exp. Cell Res. 306:24-34(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), SUBUNIT.
[3]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5). Tissue: Testis.
[4]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3 AND 4). Tissue: Skin and Testis.
[5]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 579-977. Tissue: Placenta.
[6]	"Requirement of the human GARP complex for mannose 6-phosphate-receptor-dependent sorting of cathepsin D to lysosomes." Perez-Victoria F.J., Mardones G.A., Bonifacino J.S. Mol. Biol. Cell 19:2350-2362(2008) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION, SUBCELLULAR LOCATION.
[7]	"Ang2/fat-free is a conserved subunit of the Golgi-associated retrograde protein complex." Perez-Victoria F.J., Schindler C., Magadan J.G., Mardones G.A., Delevoye C., Romao M., Raposo G., Bonifacino J.S. Mol. Biol. Cell 21:3386-3395(2010) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH VPS51.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF102177 mRNA. Translation: AAF37319.1. AY444798 mRNA. Translation: AAS20945.1. AL137604 mRNA. Translation: CAB70837.1. AL359939 mRNA. Translation: CAB95772.1. CR749701 mRNA. Translation: CAH18479.1. BC030275 mRNA. Translation: AAH30275.1. BC041868 mRNA. Translation: AAH41868.1. AK002205 mRNA. Translation: BAA92134.1. Different initiation.
IPI	IPI00163718. IPI00480073. IPI00555893. IPI00555953. IPI00556232.
PIR	T46308.
RefSeq	NP_001005739.1. NM_001005739.1. NP_057600.2. NM_016516.2.
UniGene	Hs.48499.
3D structure databases
ProteinModelPortal	Q9P1Q0.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9P1Q0. 2 interactions.
STRING	9606.ENSP00000272322.
PTM databases
PhosphoSite	Q9P1Q0.
Polymorphism databases
DMDM	82583721.
Proteomic databases
PaxDb	Q9P1Q0.
PRIDE	Q9P1Q0.
Protocols and materials databases
DNASU	51542.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000272322; ENSP00000272322; ENSG00000143952. ENST00000354504; ENSP00000346499; ENSG00000143952. ENST00000409558; ENSP00000386980; ENSG00000143952. ENST00000416400; ENSP00000414725; ENSG00000143952. ENST00000483277; ENSP00000445040; ENSG00000143952.
GeneID	51542.
KEGG	hsa:51542.
UCSC	uc002scn.3. human. uc002sco.3. human. uc002scp.3. human. uc002scq.3. human.
Organism-specific databases
CTD	51542.
GeneCards	GC02M064119.
HGNC	HGNC:18652. VPS54.
MIM	614633. gene.
neXtProt	NX_Q9P1Q0.
PharmGKB	PA134920394.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG285553.
HOVERGEN	HBG068681.
InParanoid	Q9P1Q0.
OMA	HSFRHLG.
Gene expression databases
Bgee	Q9P1Q0.
CleanEx	HS_VPS54.
Genevestigator	Q9P1Q0.
GermOnline	ENSG00000143952. Homo sapiens.
Family and domain databases
InterPro	IPR019515. Vacuolar_sorting-assoc_54. IPR012501. Vps54. [Graphical view]
Pfam	PF10475. DUF2450. 1 hit. PF07928. Vps54. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	51542.
NextBio	55313.
SOURCE	Search...

Entry information

Entry name

VPS54_HUMAN

Accession

Primary (citable) accession number: Q9P1Q0
Secondary accession number(s): Q5VIR5 , Q86YF7, Q8N6G3, Q9NPV0, Q9NT07, Q9NUJ0

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	May 1, 2013
This is version 82 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.