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Protein

Costars family protein ABRACL

Gene

ABRACL

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Costars family protein ABRACL
Alternative name(s):
ABRA C-terminal-like protein
Gene namesi
Name:ABRACL
Synonyms:C6orf115
ORF Names:HSPC280, PRO2013
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000146386.7
HGNCiHGNC:21230 ABRACL
neXtProtiNX_Q9P1F3

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000146386
PharmGKBiPA134884626

Polymorphism and mutation databases

BioMutaiABRACL

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000895211 – 81Costars family protein ABRACLAdd BLAST81

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

EPDiQ9P1F3
MaxQBiQ9P1F3
PaxDbiQ9P1F3
PeptideAtlasiQ9P1F3
PRIDEiQ9P1F3
ProteomicsDBi83647
TopDownProteomicsiQ9P1F3

PTM databases

iPTMnetiQ9P1F3
PhosphoSitePlusiQ9P1F3

Expressioni

Gene expression databases

BgeeiENSG00000146386
CleanExiHS_C6orf115
ExpressionAtlasiQ9P1F3 baseline and differential
GenevisibleiQ9P1F3 HS

Organism-specific databases

HPAiHPA030217

Interactioni

Protein-protein interaction databases

BioGridi121847, 5 interactors
IntActiQ9P1F3, 4 interactors
STRINGi9606.ENSP00000356632

Structurei

Secondary structure

181
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi3 – 17Combined sources15
Beta strandi24 – 29Combined sources6
Helixi30 – 40Combined sources11
Helixi46 – 55Combined sources10
Beta strandi58 – 60Combined sources3
Helixi69 – 71Combined sources3
Beta strandi75 – 78Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2L2ONMR-A1-81[»]
ProteinModelPortaliQ9P1F3
SMRiQ9P1F3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the costars family.Curated

Phylogenomic databases

eggNOGiKOG3376 Eukaryota
ENOG410XR7V LUCA
GeneTreeiENSGT00470000042287
HOGENOMiHOG000030934
HOVERGENiHBG050912
InParanoidiQ9P1F3
OMAiQDDKCAN
OrthoDBiEOG091G130D
PhylomeDBiQ9P1F3

Family and domain databases

Gene3Di1.10.10.1540, 1 hit
InterProiView protein in InterPro
IPR027817 Costars_dom
IPR038095 Costars_sf
PfamiView protein in Pfam
PF14705 Costars, 1 hit
SMARTiView protein in SMART
SM01283 Costars, 1 hit

Sequencei

Sequence statusi: Complete.

Q9P1F3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNVDHEVNLL VEEIHRLGSK NADGKLSVKF GVLFRDDKCA NLFEALVGTL
60 70 80
KAAKRRKIVT YPGELLLQGV HDDVDIILLQ D
Length:81
Mass (Da):9,056
Last modified:October 1, 2000 - v1
Checksum:i1F0DCE7A1D22B171
GO

Sequence cautioni

The sequence AAF28958 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF116682 mRNA Translation: AAF71102.1
AF161398 mRNA Translation: AAF28958.1 Different initiation.
AL590308 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW47902.1
BC014953 mRNA Translation: AAH14953.1
CCDSiCCDS43509.1
RefSeqiNP_067066.1, NM_021243.2
XP_016866640.1, XM_017011151.1
UniGeneiHs.600861

Genome annotation databases

EnsembliENST00000367660; ENSP00000356632; ENSG00000146386
GeneIDi58527
KEGGihsa:58527
UCSCiuc003qil.2 human

Similar proteinsi

Entry informationi

Entry nameiABRAL_HUMAN
AccessioniPrimary (citable) accession number: Q9P1F3
Secondary accession number(s): Q5SZC8, Q9P0A1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 7, 2003
Last sequence update: October 1, 2000
Last modified: June 20, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

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