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Q9P0J6 (RM36_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 99. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
39S ribosomal protein L36, mitochondrial

Short name=L36mt
Short name=MRP-L36
Alternative name(s):
BRCA1-interacting protein 1
Gene names
Name:MRPL36
Synonyms:BRIP1
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length103 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Component of the large subunit of the mitochondrial ribosome Potential. HAMAP-Rule MF_00251

Subcellular location

Mitochondrion HAMAP-Rule MF_00251.

Sequence similarities

Belongs to the ribosomal protein L36P family.

Sequence caution

The sequence AAF04788.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Cellular componentMitochondrion
   DomainTransit peptide
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtranslation

Non-traceable author statement Ref.1. Source: UniProtKB

   Cellular_componentmitochondrial large ribosomal subunit

Non-traceable author statement Ref.1. Source: UniProtKB

   Molecular_functionstructural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – ?Mitochondrion Potential
Chain? – 10339S ribosomal protein L36, mitochondrial HAMAP-Rule MF_00251PRO_0000030529

Experimental info

Sequence conflict361G → S in AAF04788. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q9P0J6 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: CF1720639DE3C34B

FASTA10311,784
        10         20         30         40         50         60 
MANLFIRKMV NPLLYLSRHT VKPRALSTFL FGSIRGAAPV AVEPGAAVRS LLSPGLLPHL 

        70         80         90        100 
LPALGFKNKT VLKKRCKDCY LVKRRGRWYV YCKTHPRHKQ RQM 

« Hide

References

« Hide 'large scale' references
[1]"Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria."
Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A., Watanabe K.
J. Biol. Chem. 276:21724-21736(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"BRIP1, a candidate for BRCA1-interacting protein."
Wang Q., Zhang H., Greene M.I.
Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[3]"Searching for interaction partners of the transcription factor REST/NRSF by two-hybrid screening."
Santana-Roman H., Curiel-Quesada E., Tapia-Ramirez J.
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[4]"Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning."
Hu R.-M., Han Z.-G., Song H.-D., Peng Y.-D., Huang Q.-H., Ren S.-X., Gu Y.-J., Huang C.-H., Li Y.-B., Jiang C.-L., Fu G., Zhang Q.-H., Gu B.-W., Dai M., Mao Y.-F., Gao G.-F., Rong R., Ye M. expand/collapse author list , Zhou J., Xu S.-H., Gu J., Shi J.-X., Jin W.-R., Zhang C.-K., Wu T.-M., Huang G.-Y., Chen Z., Chen M.-D., Chen J.-L.
Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Adrenal gland.
[5]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Thalamus.
[6]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[7]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Testis.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB049654 mRNA. Translation: BAB40859.1.
AF151109 mRNA. Translation: AAF04788.1. Different initiation.
EF036487 mRNA. Translation: ABO65073.1.
AF155653 mRNA. Translation: AAF67010.1.
AK312001 mRNA. Translation: BAG34939.1.
CH471102 Genomic DNA. Translation: EAX08145.1.
BC020642 mRNA. Translation: AAH20642.1.
BC104652 mRNA. Translation: AAI04653.1.
RefSeqNP_115868.1. NM_032479.3.
UniGeneHs.719465.

3D structure databases

ProteinModelPortalQ9P0J6.
SMRQ9P0J6. Positions 66-102.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid122366. 4 interactions.
IntActQ9P0J6. 1 interaction.
MINTMINT-1526761.
STRING9606.ENSP00000372093.

Polymorphism databases

DMDM24212267.

Proteomic databases

PRIDEQ9P0J6.

Protocols and materials databases

DNASU64979.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000382647; ENSP00000372093; ENSG00000171421.
ENST00000505059; ENSP00000423152; ENSG00000171421.
ENST00000505818; ENSP00000427152; ENSG00000171421.
ENST00000508987; ENSP00000423399; ENSG00000171421.
GeneID64979.
KEGGhsa:64979.
UCSCuc003jcx.4. human.

Organism-specific databases

CTD64979.
GeneCardsGC05M001851.
HGNCHGNC:14490. MRPL36.
HPAHPA047238.
MIM611842. gene.
neXtProtNX_Q9P0J6.
PharmGKBPA30967.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG267357.
HOGENOMHOG000111586.
HOVERGENHBG029144.
InParanoidQ9P0J6.
KOK02919.
OMARVTHILV.
OrthoDBEOG79CZ1X.
PhylomeDBQ9P0J6.
TreeFamTF300275.

Gene expression databases

ArrayExpressQ9P0J6.
BgeeQ9P0J6.
CleanExHS_BRIP1.
HS_MRPL36.
GenevestigatorQ9P0J6.

Family and domain databases

HAMAPMF_00251. Ribosomal_L36.
InterProIPR000473. Ribosomal_L36.
[Graphical view]
PANTHERPTHR18804. PTHR18804. 1 hit.
PfamPF00444. Ribosomal_L36. 1 hit.
[Graphical view]
SUPFAMSSF57840. SSF57840. 1 hit.
TIGRFAMsTIGR01022. rpmJ_bact. 1 hit.
ProtoNetSearch...

Other

GenomeRNAi64979.
NextBio67168.
PROQ9P0J6.
SOURCESearch...

Entry information

Entry nameRM36_HUMAN
AccessionPrimary (citable) accession number: Q9P0J6
Secondary accession number(s): A4UCS0 expand/collapse secondary AC list , B2R4Z2, Q3SWV6, Q9UKL7
Entry history
Integrated into UniProtKB/Swiss-Prot: October 19, 2002
Last sequence update: October 1, 2000
Last modified: February 19, 2014
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human chromosome 5

Human chromosome 5: entries, gene names and cross-references to MIM