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Q9P035

- HACD3_HUMAN

UniProt

Q9P035 - HACD3_HUMAN

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Protein
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3
Gene
PTPLAD1, BIND1, HACD3
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Responsible for the dehydration step in very long-chain fatty acid (VLCFA) synthesis. Involved in Rac1-signaling pathways leading to the modulation of gene expression.2 Publications

Catalytic activityi

A very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain trans-2,3-dehydroacyl-CoA + H2O.1 Publication

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei286 – 2861 By similarity
Active sitei293 – 2931 By similarity

GO - Molecular functioni

  1. GTPase activator activity Source: ProtInc
  2. lyase activity Source: UniProtKB-KW
  3. protein binding Source: IntAct

GO - Biological processi

  1. I-kappaB kinase/NF-kappaB signaling Source: ProtInc
  2. Rac protein signal transduction Source: UniProtKB
  3. Rho protein signal transduction Source: Ensembl
  4. activation of JUN kinase activity Source: ProtInc
  5. fatty acid biosynthetic process Source: UniProtKB-KW
  6. positive regulation of GTPase activity Source: GOC
  7. small GTPase mediated signal transduction Source: ProtInc
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (EC:4.2.1.134)
Alternative name(s):
3-hydroxyacyl-CoA dehydratase 3
Short name:
HACD3
Butyrate-induced protein 1
Short name:
B-ind1
Short name:
hB-ind1
Protein tyrosine phosphatase-like protein PTPLAD1
Protein-tyrosine phosphatase-like A domain-containing protein 1
Gene namesi
Name:PTPLAD1
Synonyms:BIND1, HACD3
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 15

Organism-specific databases

HGNCiHGNC:24175. PTPLAD1.

Subcellular locationi

Endoplasmic reticulum membrane; Multi-pass membrane protein 1 Publication

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 149149Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei150 – 17021Helical; Reviewed prediction
Add
BLAST
Topological domaini171 – 18515Lumenal Reviewed prediction
Add
BLAST
Transmembranei186 – 20722Helical; Reviewed prediction
Add
BLAST
Topological domaini208 – 21710Cytoplasmic Reviewed prediction
Transmembranei218 – 23518Helical; Reviewed prediction
Add
BLAST
Topological domaini236 – 2416Lumenal Reviewed prediction
Transmembranei242 – 25615Helical; Reviewed prediction
Add
BLAST
Topological domaini257 – 27923Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei280 – 29819Helical; Reviewed prediction
Add
BLAST
Topological domaini299 – 32224Lumenal Reviewed prediction
Add
BLAST
Transmembranei323 – 34321Helical; Reviewed prediction
Add
BLAST
Topological domaini344 – 36219Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. endoplasmic reticulum membrane Source: UniProtKB-SubCell
  2. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142671113.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 362362Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3
PRO_0000313724Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei114 – 1141Phosphoserine8 Publications

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9P035.
PaxDbiQ9P035.
PRIDEiQ9P035.

PTM databases

PhosphoSiteiQ9P035.

Expressioni

Tissue specificityi

Highly expressed in testis, kidney, brain, liver and weakly in skeletal muscle, spleen and heart. No expression detected in leukocytes.2 Publications

Inductioni

By AKAP12 and histone deacetylase inhibitors such as sodium butyrate.1 Publication

Gene expression databases

ArrayExpressiQ9P035.
BgeeiQ9P035.
CleanExiHS_PTPLAD1.
GenevestigatoriQ9P035.

Organism-specific databases

HPAiHPA014837.

Interactioni

Subunit structurei

Interacts with the condensation enzymes of the ELOVL family. Interacts with RAC1.2 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
Q034632EBI-359013,EBI-8803426From a different organism.
Q99IB82EBI-359013,EBI-6927873From a different organism.
Q9WMX23EBI-359013,EBI-6863748From a different organism.

Protein-protein interaction databases

BioGridi119570. 24 interactions.
IntActiQ9P035. 21 interactions.
MINTiMINT-1135933.

Structurei

3D structure databases

ProteinModelPortaliQ9P035.
SMRiQ9P035. Positions 5-158.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 9490CS
Add
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili111 – 13626 Reviewed prediction
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi350 – 3534Poly-Arg
Compositional biasi357 – 3604Poly-Lys

Sequence similaritiesi

Contains 1 CS domain.

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG5198.
HOVERGENiHBG108301.
InParanoidiQ9P035.
OrthoDBiEOG7BP82H.
PhylomeDBiQ9P035.
TreeFamiTF313326.

Family and domain databases

Gene3Di2.60.40.790. 1 hit.
InterProiIPR007052. CS_dom.
IPR008978. HSP20-like_chaperone.
IPR007482. Tyr_Pase-like_PTPLA.
[Graphical view]
PANTHERiPTHR11035. PTHR11035. 1 hit.
PfamiPF04969. CS. 1 hit.
PF04387. PTPLA. 1 hit.
[Graphical view]
SUPFAMiSSF49764. SSF49764. 1 hit.
PROSITEiPS51203. CS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9P035-1 [UniParc]FASTAAdd to Basket

« Hide

MENQVLTPHV YWAQRHRELY LRVELSDVQN PAISITENVL HFKAQGHGAK    50
GDNVYEFHLE FLDLVKPEPV YKLTQRQVNI TVQKKVSQWW ERLTKQEKRP 100
LFLAPDFDRW LDESDAEMEL RAKEEERLNK LRLESEGSPE TLTNLRKGYL 150
FMYNLVQFLG FSWIFVNLTV RFCILGKESF YDTFHTVADM MYFCQMLAVV 200
ETINAAIGVT TSPVLPSLIQ LLGRNFILFI IFGTMEEMQN KAVVFFVFYL 250
WSAIEIFRYS FYMLTCIDMD WKVLTWLRYT LWIPLYPLGC LAEAVSVIQS 300
IPIFNETGRF SFTLPYPVKI KVRFSFFLQI YLIMIFLGLY INFRHLYKQR 350
RRRYGQKKKK IH 362
Length:362
Mass (Da):43,160
Last modified:January 15, 2008 - v2
Checksum:i1B3591E88DD85D16
GO

Sequence cautioni

The sequence AAF29085.1 differs from that shown. Reason: Frameshift at position 356.
The sequence BAC11249.1 differs from that shown. Reason: Frameshift at position 359.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti56 – 561E → K.
Corresponds to variant rs11632737 [ dbSNP | Ensembl ].
VAR_037712
Natural varianti269 – 2691M → L.
Corresponds to variant rs2279854 [ dbSNP | Ensembl ].
VAR_037713

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti60 – 601E → K in BAB55101. 1 Publication
Sequence conflicti245 – 2451F → I in BAC11277. 1 Publication
Sequence conflicti282 – 2821W → G in AAH35508. 1 Publication
Sequence conflicti292 – 2921A → V in AAF29085. 1 Publication
Sequence conflicti352 – 36211RRYGQKKKKIH → LKMRAGAVAHACDPSALGG in CAB69070. 1 Publication
Add
BLAST
Sequence conflicti361 – 3611I → K in AAH35508. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ271091 mRNA. Translation: CAB69070.1.
AF161470 mRNA. Translation: AAF29085.1. Frameshift.
AK027421 mRNA. Translation: BAB55101.1.
AK074857 mRNA. Translation: BAC11249.1. Frameshift.
AK074898 mRNA. Translation: BAC11277.1.
BC019873 mRNA. Translation: AAH19873.1.
BC035508 mRNA. Translation: AAH35508.1.
BC047685 mRNA. Translation: AAH47685.1.
BC058912 mRNA. Translation: AAH58912.1.
DQ251107 Genomic DNA. Translation: ABB83547.1.
CCDSiCCDS45282.1.
RefSeqiNP_057479.2. NM_016395.2.
UniGeneiHs.512973.

Genome annotation databases

EnsembliENST00000261875; ENSP00000261875; ENSG00000074696.
GeneIDi51495.
KEGGihsa:51495.
UCSCiuc002apc.3. human.

Polymorphism databases

DMDMi166199462.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ271091 mRNA. Translation: CAB69070.1 .
AF161470 mRNA. Translation: AAF29085.1 . Frameshift.
AK027421 mRNA. Translation: BAB55101.1 .
AK074857 mRNA. Translation: BAC11249.1 . Frameshift.
AK074898 mRNA. Translation: BAC11277.1 .
BC019873 mRNA. Translation: AAH19873.1 .
BC035508 mRNA. Translation: AAH35508.1 .
BC047685 mRNA. Translation: AAH47685.1 .
BC058912 mRNA. Translation: AAH58912.1 .
DQ251107 Genomic DNA. Translation: ABB83547.1 .
CCDSi CCDS45282.1.
RefSeqi NP_057479.2. NM_016395.2.
UniGenei Hs.512973.

3D structure databases

ProteinModelPortali Q9P035.
SMRi Q9P035. Positions 5-158.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 119570. 24 interactions.
IntActi Q9P035. 21 interactions.
MINTi MINT-1135933.

PTM databases

PhosphoSitei Q9P035.

Polymorphism databases

DMDMi 166199462.

Proteomic databases

MaxQBi Q9P035.
PaxDbi Q9P035.
PRIDEi Q9P035.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000261875 ; ENSP00000261875 ; ENSG00000074696 .
GeneIDi 51495.
KEGGi hsa:51495.
UCSCi uc002apc.3. human.

Organism-specific databases

CTDi 51495.
GeneCardsi GC15P065822.
H-InvDB HIX0012353.
HGNCi HGNC:24175. PTPLAD1.
HPAi HPA014837.
neXtProti NX_Q9P035.
PharmGKBi PA142671113.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG5198.
HOVERGENi HBG108301.
InParanoidi Q9P035.
OrthoDBi EOG7BP82H.
PhylomeDBi Q9P035.
TreeFami TF313326.

Miscellaneous databases

ChiTaRSi PTPLAD1. human.
GeneWikii PTPLAD1.
GenomeRNAii 51495.
NextBioi 55161.
PROi Q9P035.

Gene expression databases

ArrayExpressi Q9P035.
Bgeei Q9P035.
CleanExi HS_PTPLAD1.
Genevestigatori Q9P035.

Family and domain databases

Gene3Di 2.60.40.790. 1 hit.
InterProi IPR007052. CS_dom.
IPR008978. HSP20-like_chaperone.
IPR007482. Tyr_Pase-like_PTPLA.
[Graphical view ]
PANTHERi PTHR11035. PTHR11035. 1 hit.
Pfami PF04969. CS. 1 hit.
PF04387. PTPLA. 1 hit.
[Graphical view ]
SUPFAMi SSF49764. SSF49764. 1 hit.
PROSITEi PS51203. CS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "B-ind1, a novel mediator of Rac1 signaling cloned from sodium butyrate-treated fibroblasts."
    Courilleau D., Chastre E., Sabbah M., Redeuilh G., Atfi A., Mester J.
    J. Biol. Chem. 275:17344-17348(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, INTERACTION WITH RAC1, TISSUE SPECIFICITY.
  2. "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells."
    Zhang Q.-H., Ye M., Wu X.-Y., Ren S.-X., Zhao M., Zhao C.-J., Fu G., Shen Y., Fan H.-Y., Lu G., Zhong M., Xu X.-R., Han Z.-G., Zhang J.-W., Tao J., Huang Q.-H., Zhou J., Hu G.-X.
    , Gu J., Chen S.-J., Chen Z.
    Genome Res. 10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Umbilical cord blood.
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: B-cell, Duodenum, Eye and Urinary bladder.
  5. "Human B-ind1 gene promoter: cloning and regulation by histone deacetylase inhibitors."
    Sabbah M., Saucier C., Redeuilh G.
    Gene 374:128-133(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-29.
  6. "SSeCKS/Gravin/AKAP12 attenuates expression of proliferative and angiogenic genes during suppression of v-Src-induced oncogenesis."
    Liu Y., Gao L., Gelman I.H.
    BMC Cancer 6:105-105(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION BY AKAP12.
  7. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
    Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
    Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-114, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  8. "Characterization of four mammalian 3-hydroxyacyl-CoA dehydratases involved in very long-chain fatty acid synthesis."
    Ikeda M., Kanao Y., Yamanaka M., Sakuraba H., Mizutani Y., Igarashi Y., Kihara A.
    FEBS Lett. 582:2435-2440(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION, CATALYTIC ACTIVITY, TISSUE SPECIFICITY, INTERACTION WITH ELOVL FAMILY.
  9. "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
    Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D., Yates J.R. III
    J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-114, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  10. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
    Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M.
    Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-114, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  11. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  12. "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."
    Han G., Ye M., Zhou H., Jiang X., Feng S., Jiang X., Tian R., Wan D., Zou H., Gu J.
    Proteomics 8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-114, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.
  13. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-114, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  14. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-114, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  15. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-114, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  16. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  17. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-114, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiHACD3_HUMAN
AccessioniPrimary (citable) accession number: Q9P035
Secondary accession number(s): A0PJA1
, Q280Z3, Q6PD63, Q8IUI5, Q8NC86, Q8NCB1, Q96T12, Q9NQA7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 15, 2008
Last modified: September 3, 2014
This is version 97 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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