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Protein
Submitted name:

14 kDa phosphohistidine phosphatase

Gene

PHPT1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. phosphohistidine phosphatase activity Source: InterPro

GO - Biological processi

  1. peptidyl-histidine dephosphorylation Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
14 kDa phosphohistidine phosphataseImported
Submitted name:
HSPC141Imported
Gene namesi
Name:PHPT1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 9

Organism-specific databases

HGNCiHGNC:30033. PHPT1.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: InterPro
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134948141.

PTM / Processingi

Proteomic databases

PRIDEiQ9P019.

Expressioni

Gene expression databases

ExpressionAtlasiQ9P019. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ9P019.
SMRiQ9P019. Positions 1-34.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000002738.

Family and domain databases

InterProiIPR007702. Janus.
IPR028441. PHPT1.
[Graphical view]
PANTHERiPTHR12258:SF10. PTHR12258:SF10. 1 hit.
PfamiPF05005. Ocnus. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9P019-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAVADLALIP DVDIDSDGVF KYVLIRVHSA PRSGLRLQRA RRSCAATSGL
60 70 80 90 100
STMRTSTTKC RATCRSKAAT VSVWAAGASP TRVRTRRFTC TAIPWPMVLP
110 120 130 140 150
STPFQLRKSK PSTPTTRSPG LTTATEHSQP GACCLQQPLQ SPAFACTPLA
160 170 180
GLALPAPAAA SGDVLSTRPW RQASLATELN VLPHLPAS
Length:188
Mass (Da):19,890
Last modified:October 1, 2000 - v1
Checksum:i33054DD11FAFB9B4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL355987 Genomic DNA. No translation available.
AF161490 mRNA. Translation: AAF29105.1.
UniGeneiHs.409834.
Hs.731711.

Genome annotation databases

EnsembliENST00000545326; ENSP00000444757; ENSG00000054148.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL355987 Genomic DNA. No translation available.
AF161490 mRNA. Translation: AAF29105.1.
UniGeneiHs.409834.
Hs.731711.

3D structure databases

ProteinModelPortaliQ9P019.
SMRiQ9P019. Positions 1-34.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ9P019.

Protocols and materials databases

DNASUi29085.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000545326; ENSP00000444757; ENSG00000054148.

Organism-specific databases

HGNCiHGNC:30033. PHPT1.
PharmGKBiPA134948141.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00390000002738.

Miscellaneous databases

NextBioi52068.

Gene expression databases

ExpressionAtlasiQ9P019. baseline and differential.

Family and domain databases

InterProiIPR007702. Janus.
IPR028441. PHPT1.
[Graphical view]
PANTHERiPTHR12258:SF10. PTHR12258:SF10. 1 hit.
PfamiPF05005. Ocnus. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells."
    Zhang Q.H., Ye M., Wu X.Y., Ren S.X., Zhao M., Zhao C.J., Fu G., Shen Y., Fan H.Y., Lu G., Zhong M., Xu X.R., Han Z.G., Zhang J.W., Tao J., Huang Q.H., Zhou J., Hu G.X.
    , Gu J., Chen S.J., Chen Z.
    Genome Res. 10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BloodImported.
  2. "DNA sequence and analysis of human chromosome 9."
    Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
    , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
    Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Ensembl
    Submitted (NOV-2014) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiQ9P019_HUMAN
AccessioniPrimary (citable) accession number: Q9P019
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: January 7, 2015
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.