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Q9P015 (RM15_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 100. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
39S ribosomal protein L15, mitochondrial

Short name=L15mt
Short name=MRP-L15
Gene names
Name:MRPL15
ORF Names:HSPC145
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length296 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Mitochondrion By similarity.

Sequence similarities

Belongs to the ribosomal protein L15P family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 2121Mitochondrion By similarity
Chain22 – 29627539S ribosomal protein L15, mitochondrial
PRO_0000257838

Regions

Compositional bias38 – 6427Arg-rich

Experimental info

Sequence conflict961L → M in CAB66600. Ref.2
Sequence conflict961L → M in CAG38562. Ref.3
Sequence conflict1371G → D in CAB66600. Ref.2
Sequence conflict1371G → D in CAG38562. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Q9P015 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: D7396086F808A72C

FASTA29633,420
        10         20         30         40         50         60 
MAGPLQGGGA RALDLLRGLP RVSLANLKPN PGSKKPERRP RGRRRGRKCG RGHKGERQRG 

        70         80         90        100        110        120 
TRPRLGFEGG QTPFYIRIPK YGFNEGHSFR RQYKPLSLNR LQYLIDLGRV DPSQPIDLTQ 

       130        140        150        160        170        180 
LVNGRGVTIQ PLKRDYGVQL VEEGADTFTA KVNIEVQLAS ELAIAAIEKN GGVVTTAFYD 

       190        200        210        220        230        240 
PRSLDIVCKP VPFFLRGQPI PKRMLPPEEL VPYYTDAKNR GYLADPAKFP EARLELARKY 

       250        260        270        280        290 
GYILPDITKD ELFKMLCTRK DPRQIFFGLA PGWVVNMADK KILKPTDENL LKYYTS 

« Hide

References

« Hide 'large scale' references
[1]"Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells."
Zhang Q.-H., Ye M., Wu X.-Y., Ren S.-X., Zhao M., Zhao C.-J., Fu G., Shen Y., Fan H.-Y., Lu G., Zhong M., Xu X.-R., Han Z.-G., Zhang J.-W., Tao J., Huang Q.-H., Zhou J., Hu G.-X. expand/collapse author list , Gu J., Chen S.-J., Chen Z.
Genome Res. 10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Blood.
[2]"Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs."
Wiemann S., Weil B., Wellenreuther R., Gassenhuber J., Glassl S., Ansorge W., Boecher M., Bloecker H., Bauersachs S., Blum H., Lauber J., Duesterhoeft A., Beyer A., Koehrer K., Strack N., Mewes H.-W., Ottenwaelder B., Obermaier B. expand/collapse author list , Tampe J., Heubner D., Wambutt R., Korn B., Klein M., Poustka A.
Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Fetal brain.
[3]"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[4]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Cervix.
[5]"The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders."
Kenmochi N., Suzuki T., Uechi T., Magoori M., Kuniba M., Higa S., Watanabe K., Tanaka T.
Genomics 77:65-70(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 259-296.
[6]"Initial characterization of the human central proteome."
Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[7]"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.
Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF161494 mRNA. Translation: AAF29109.1.
AL136665 mRNA. Translation: CAB66600.1.
CR533531 mRNA. Translation: CAG38562.1.
BC000891 mRNA. Translation: AAH00891.1.
AB051619 Genomic DNA. Translation: BAB54947.1.
CCDSCCDS6158.1.
RefSeqNP_054894.1. NM_014175.3.
UniGeneHs.18349.

3D structure databases

ProteinModelPortalQ9P015.
SMRQ9P015. Positions 22-177.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid118857. 34 interactions.
IntActQ9P015. 5 interactions.
MINTMINT-3066248.
STRING9606.ENSP00000260102.

PTM databases

PhosphoSiteQ9P015.

Polymorphism databases

DMDM74734761.

Proteomic databases

MaxQBQ9P015.
PaxDbQ9P015.
PeptideAtlasQ9P015.
PRIDEQ9P015.

Protocols and materials databases

DNASU29088.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000260102; ENSP00000260102; ENSG00000137547.
GeneID29088.
KEGGhsa:29088.
UCSCuc003xsa.2. human.

Organism-specific databases

CTD29088.
GeneCardsGC08P055097.
HGNCHGNC:14054. MRPL15.
HPAHPA044425.
MIM611828. gene.
neXtProtNX_Q9P015.
PharmGKBPA30944.
GenAtlasSearch...

Phylogenomic databases

eggNOGCOG0200.
HOGENOMHOG000231264.
HOVERGENHBG088294.
InParanoidQ9P015.
KOK02876.
OMAHGAGNKG.
OrthoDBEOG7NKKNG.
PhylomeDBQ9P015.
TreeFamTF105918.

Gene expression databases

ArrayExpressQ9P015.
BgeeQ9P015.
CleanExHS_MRPL15.
GenevestigatorQ9P015.

Family and domain databases

InterProIPR005749. Ribosomal_L15_bac-type.
IPR021131. Ribosomal_L18e/L15P.
[Graphical view]
PANTHERPTHR12934. PTHR12934. 1 hit.
PfamPF00828. Ribosomal_L18e. 1 hit.
[Graphical view]
SUPFAMSSF52080. SSF52080. 1 hit.
ProtoNetSearch...

Other

ChiTaRSMRPL15. human.
GeneWikiMRPL15.
GenomeRNAi29088.
NextBio52090.
PROQ9P015.
SOURCESearch...

Entry information

Entry nameRM15_HUMAN
AccessionPrimary (citable) accession number: Q9P015
Secondary accession number(s): Q96Q54, Q9H0Y1
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 1, 2000
Last modified: July 9, 2014
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human chromosome 8

Human chromosome 8: entries, gene names and cross-references to MIM