Reviewed,
UniProtKB/Swiss-Prot Q9NZU5 (LMCD1_HUMAN)
Last modified
June 16, 2009.
Version 59.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: LIM and cysteine-rich domains protein 1 Alternative name(s): Dyxin | ||
| Gene names |
| ||
| Organism | Homo sapiens (Human) | ||
| Taxonomic identifier | 9606 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Protein attributes
| Sequence length | 365 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Subunit structure | Interacts with beta-dystroglycan. |
| Tissue specificity | Expressed in many tissues with highest abundance in skeletal muscle. |
| Sequence similarities | Contains 2 LIM zinc-binding domains. Contains 1 PET domain. |
Ontologies
| Keywords | |
|---|---|
| Domain | LIM domain Repeat |
| Ligand | Metal-binding Zinc |
| Gene Ontology (GO) | |
| Molecular function | zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Identification of a novel LIM domain gene, LMCD1, and chromosomal localization in human and mouse." Bespalova I.N., Burmeister M. Genomics 63:69-74(2000) [PubMed: 10662546] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. |
| [2] | "Identification of Dyxin: a novel intracellular binding partner of beta-dystroglycan." Holt H.H., Crosbie R.H., Saito F., Campbell K.P. Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. |
| [3] | "Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. Sugano S.Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Mammary gland. |
| [4] | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Eye. |
Cross-references
Sequence databases | |
|---|---|
| AF169284 mRNA. Translation: AAF34411.1. AF216709 mRNA. Translation: AAG36778.1. AK022176 mRNA. Translation: BAB13976.1. BC000646 mRNA. Translation: AAH00646.1. | |
| IPI | IPI00303258. |
| RefSeq | NP_055398.1. |
| UniGene | Hs.475353 |
3D structure databases | |
| HSSP | HSSP built from PDB template 1CTL based on UniProtKB P32965. |
| ModBase | Search... |
Proteomic databases | |
| PeptideAtlas | Q9NZU5. |
| PRIDE | Q9NZU5. |
Genome annotation databases | |
| Ensembl | ENSG00000071282. Homo sapiens. [Contig view] |
| GeneID | 29995. |
| KEGG | hsa:29995. |
Organism-specific databases | |
| GeneCards | GC03P008518. |
| H-InvDB | HIX0003018. |
| HGNC | HGNC:6633. LMCD1. |
| MIM | 604859. gene. |
| PharmGKB | PA30401. |
| GenAtlas | Search... |
Phylogenomic databases | |
| HOGENOM | Q9NZU5. |
| HOVERGEN | Q9NZU5. |
Gene expression databases | |
| ArrayExpress | Q9NZU5. |
| Bgee | Q9NZU5. |
| CleanEx | HS_LMCD1. |
| GermOnline | ENSG00000071282. Homo sapiens. |
Family and domain databases | |
| InterPro | IPR010442. PET_domain. IPR001781. Znf_LIM. [Graphical view] |
| Gene3D | G3DSA:2.10.110.10. Znf_LIM. 1 hit. |
| Pfam | PF00412. LIM. 2 hits. PF06297. PET. 1 hit. [Graphical view] |
| ProDom | PD000094. LIM. 2 hits. [Graphical view] [Entries sharing at least one domain] |
| SMART | SM00132. LIM. 2 hits. [Graphical view] |
| PROSITE | PS00478. LIM_DOMAIN_1. 2 hits. PS50023. LIM_DOMAIN_2. 2 hits. PS51303. PET. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 52796. |
| SOURCE | Search... |
Entry information
| Entry name | LMCD1_HUMAN | ||||||||
| Accession | Primary (citable) accession number: Q9NZU5 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HPI (Human Proteome Initiative) | ||||||||
Relevant documents
| Human chromosome 3 Human chromosome 3: entries, gene names and cross-references to MIM |
| MIM cross-references Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot |
| SIMILARITY comments Index of protein domains and families |

Clusters with


