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Protein

Opioid growth factor receptor

Gene

OGFR

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Receptor for opioid growth factor (OGF), also known as Met-enkephalin. Seems to be involved in growth regulation.

GO - Molecular functioni

  • opioid receptor activity Source: UniProtKB

GO - Biological processi

  • opioid receptor signaling pathway Source: GOC
  • regulation of cell growth Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Receptor

Keywords - Biological processi

Growth regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Opioid growth factor receptor
Short name:
OGFr
Alternative name(s):
Protein 7-60
Zeta-type opioid receptor
Gene namesi
Name:OGFR
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 20

Organism-specific databases

HGNCiHGNC:15768. OGFR.

Subcellular locationi

  • Cytoplasm By similarity
  • Nucleus By similarity

  • Note: The OGF/OGFR complex is probably translocated to the nucleus.

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31911.

Polymorphism and mutation databases

BioMutaiOGFR.
DMDMi146331047.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 677677Opioid growth factor receptorPRO_0000058030Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionine1 Publication
Modified residuei315 – 3151Phosphoserine4 Publications
Modified residuei361 – 3611Phosphoserine1 Publication
Modified residuei378 – 3781Phosphoserine6 Publications
Modified residuei420 – 4201Phosphoserine1 Publication
Modified residuei484 – 4841Phosphoserine2 Publications
Modified residuei537 – 5371Phosphoserine1 Publication
Modified residuei557 – 5571Phosphoserine1 Publication
Modified residuei617 – 6171Phosphoserine1 Publication

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiQ9NZT2.
PaxDbiQ9NZT2.
PRIDEiQ9NZT2.

PTM databases

PhosphoSiteiQ9NZT2.

Expressioni

Tissue specificityi

Highly expressed in the heart and liver, moderately in skeletal muscle and kidney and to a lesser extent in brain and pancreas. Expressed in fetal tissues including liver and kidney.

Gene expression databases

BgeeiQ9NZT2.
ExpressionAtlasiQ9NZT2. baseline and differential.
GenevisibleiQ9NZT2. HS.

Organism-specific databases

HPAiHPA017899.

Interactioni

Protein-protein interaction databases

BioGridi116239. 16 interactions.
MINTiMINT-5005689.

Structurei

3D structure databases

ProteinModelPortaliQ9NZT2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati517 – 536201Add
BLAST
Repeati537 – 556202Add
BLAST
Repeati557 – 576203Add
BLAST
Repeati577 – 596204Add
BLAST
Repeati597 – 616205Add
BLAST
Repeati617 – 636206Add
BLAST
Repeati637 – 656207Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni517 – 6561407 X 20 AA approximate tandem repeats of [ST]-P-S-E-T-P-G-P-[SR]-P-A-G-P-[AT]-[GR]-D-E-P-A-[EK]Add
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi267 – 28317Bipartite nuclear localization signalSequence AnalysisAdd
BLAST

Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiNOG28316.
GeneTreeiENSGT00390000018730.
HOVERGENiHBG024736.
InParanoidiQ9NZT2.
OMAiNWRSHNN.
OrthoDBiEOG7RV9G9.
PhylomeDBiQ9NZT2.
TreeFamiTF331377.

Family and domain databases

InterProiIPR006757. OGF_rcpt.
IPR006770. OGF_rcpt_rpt.
[Graphical view]
PfamiPF04680. OGFr_III. 7 hits.
PF04664. OGFr_N. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q9NZT2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MDDPDCDSTW EEDEEDAEDA EDEDCEDGEA AGARDADAGD EDEESEEPRA
60 70 80 90 100
ARPSSFQSRM TGSRNWRATR DMCRYRHNYP DLVERDCNGD TPNLSFYRNE
110 120 130 140 150
IRFLPNGCFI EDILQNWTDN YDLLEDNHSY IQWLFPLREP GVNWHAKPLT
160 170 180 190 200
LREVEVFKSS QEIQERLVRA YELMLGFYGI RLEDRGTGTV GRAQNYQKRF
210 220 230 240 250
QNLNWRSHNN LRITRILKSL GELGLEHFQA PLVRFFLEET LVRRELPGVR
260 270 280 290 300
QSALDYFMFA VRCRHQRRQL VHFAWEHFRP RCKFVWGPQD KLRRFKPSSL
310 320 330 340 350
PHPLEGSRKV EEEGSPGDPD HEASTQGRTC GPEHSKGGGR VDEGPQPRSV
360 370 380 390 400
EPQDAGPLER SQGDEAGGHG EDRPEPLSPK ESKKRKLELS RREQPPTEPG
410 420 430 440 450
PQSASEVEKI ALNLEGCALS QGSLRTGTQE VGGQDPGEAV QPCRQPLGAR
460 470 480 490 500
VADKVRKRRK VDEGAGDSAA VASGGAQTLA LAGSPAPSGH PKAGHSENGV
510 520 530 540 550
EEDTEGRTGP KEGTPGSPSE TPGPSPAGPA GDEPAESPSE TPGPRPAGPA
560 570 580 590 600
GDEPAESPSE TPGPRPAGPA GDEPAESPSE TPGPSPAGPT RDEPAESPSE
610 620 630 640 650
TPGPRPAGPA GDEPAESPSE TPGPRPAGPA GDEPAESPSE TPGPSPAGPT
660 670
RDEPAKAGEA AELQDAEVES SAKSGKP
Length:677
Mass (Da):73,325
Last modified:March 6, 2007 - v3
Checksum:iD4DD6AF86291B663
GO
Isoform 2 (identifier: Q9NZT2-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     558-577: Missing.

Show »
Length:657
Mass (Da):71,424
Checksum:iB7A3F384ECCE5FB7
GO

Sequence cautioni

The sequence AAD03737.1 differs from that shown. Reason: Frameshift at positions 1 and 181. Curated
The sequence AAD03745.1 differs from that shown. Reason: Frameshift at positions 1 and 181. Curated
The sequence CAC28882.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti27 – 282DG → EA (Ref. 2) Curated
Sequence conflicti37 – 8044DAGDE…RHNYP → GARRALGVLGQPGGLQMRLP ERHGGPQGSLCLMDPCCPLS LALQ (PubMed:11214971).CuratedAdd
BLAST
Sequence conflicti50 – 523AAR → GPE (Ref. 2) Curated
Sequence conflicti172 – 1721E → A (Ref. 2) Curated
Sequence conflicti220 – 2212LG → PC in AAF64404 (PubMed:10677613).Curated
Sequence conflicti220 – 2212LG → PC in AAF64405 (PubMed:10677613).Curated
Sequence conflicti224 – 2241G → S in AAF64404 (PubMed:10677613).Curated
Sequence conflicti224 – 2241G → S in AAF64405 (PubMed:10677613).Curated
Sequence conflicti224 – 2241G → S in AAF64406 (PubMed:10677613).Curated
Sequence conflicti240 – 2401T → S in AAD03745 (Ref. 2) Curated
Sequence conflicti240 – 2401T → S in AAD03737 (Ref. 2) Curated
Sequence conflicti262 – 2621R → G in AAD03745 (Ref. 2) Curated
Sequence conflicti262 – 2621R → G in AAD03737 (Ref. 2) Curated
Sequence conflicti331 – 3311G → E in AAF64406 (PubMed:10677613).Curated
Sequence conflicti398 – 3981E → G in AAF64406 (PubMed:10677613).Curated
Sequence conflicti465 – 4651A → T in AAF64406 (PubMed:10677613).Curated
Sequence conflicti535 – 5351A → AKTPSETPGPSPAGPTRDEP A in AAF64405 (PubMed:10677613).Curated
Sequence conflicti564 – 5641P → L in AAF64404 (PubMed:10677613).Curated
Sequence conflicti576 – 5761E → K in AAF64406 (PubMed:10677613).Curated
Sequence conflicti576 – 5761E → K (Ref. 2) Curated
Sequence conflicti576 – 5761E → K in BAB15775 (PubMed:11214971).Curated
Sequence conflicti577 – 5771S → I in AAF64406 (PubMed:10677613).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti545 – 5451R → S.
Corresponds to variant rs6122313 [ dbSNP | Ensembl ].
VAR_059706
Natural varianti577 – 5771S → T.3 Publications
Corresponds to variant rs6122315 [ dbSNP | Ensembl ].
VAR_030011

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei558 – 57720Missing in isoform 2. 2 PublicationsVSP_004060Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF172451 mRNA. Translation: AAF64404.1.
AF172452 mRNA. Translation: AAF64405.1.
AF172453 mRNA. Translation: AAF64406.1.
AF112980 Genomic DNA. Translation: AAD03745.1. Frameshift.
AF109134 mRNA. Translation: AAD03737.1. Frameshift.
AL035669 Genomic DNA. Translation: CAC28882.1. Sequence problems.
AL035669 Genomic DNA. Translation: CAI95763.1.
BC014137 mRNA. Translation: AAH14137.1.
AK024485 mRNA. Translation: BAB15775.1.
CCDSiCCDS13504.1. [Q9NZT2-1]
RefSeqiNP_031372.2. NM_007346.2. [Q9NZT2-1]
UniGeneiHs.67896.

Genome annotation databases

EnsembliENST00000290291; ENSP00000290291; ENSG00000060491. [Q9NZT2-1]
GeneIDi11054.
KEGGihsa:11054.
UCSCiuc002ydj.3. human. [Q9NZT2-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Web resourcesi

Wikipedia

OGFr entry

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF172451 mRNA. Translation: AAF64404.1.
AF172452 mRNA. Translation: AAF64405.1.
AF172453 mRNA. Translation: AAF64406.1.
AF112980 Genomic DNA. Translation: AAD03745.1. Frameshift.
AF109134 mRNA. Translation: AAD03737.1. Frameshift.
AL035669 Genomic DNA. Translation: CAC28882.1. Sequence problems.
AL035669 Genomic DNA. Translation: CAI95763.1.
BC014137 mRNA. Translation: AAH14137.1.
AK024485 mRNA. Translation: BAB15775.1.
CCDSiCCDS13504.1. [Q9NZT2-1]
RefSeqiNP_031372.2. NM_007346.2. [Q9NZT2-1]
UniGeneiHs.67896.

3D structure databases

ProteinModelPortaliQ9NZT2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi116239. 16 interactions.
MINTiMINT-5005689.

PTM databases

PhosphoSiteiQ9NZT2.

Polymorphism and mutation databases

BioMutaiOGFR.
DMDMi146331047.

Proteomic databases

MaxQBiQ9NZT2.
PaxDbiQ9NZT2.
PRIDEiQ9NZT2.

Protocols and materials databases

DNASUi11054.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000290291; ENSP00000290291; ENSG00000060491. [Q9NZT2-1]
GeneIDi11054.
KEGGihsa:11054.
UCSCiuc002ydj.3. human. [Q9NZT2-1]

Organism-specific databases

CTDi11054.
GeneCardsiGC20P061436.
H-InvDBHIX0015988.
HGNCiHGNC:15768. OGFR.
HPAiHPA017899.
MIMi606459. gene.
neXtProtiNX_Q9NZT2.
PharmGKBiPA31911.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG28316.
GeneTreeiENSGT00390000018730.
HOVERGENiHBG024736.
InParanoidiQ9NZT2.
OMAiNWRSHNN.
OrthoDBiEOG7RV9G9.
PhylomeDBiQ9NZT2.
TreeFamiTF331377.

Miscellaneous databases

ChiTaRSiOGFR. human.
GeneWikiiOGFr.
GenomeRNAii11054.
NextBioi41999.
PROiQ9NZT2.
SOURCEiSearch...

Gene expression databases

BgeeiQ9NZT2.
ExpressionAtlasiQ9NZT2. baseline and differential.
GenevisibleiQ9NZT2. HS.

Family and domain databases

InterProiIPR006757. OGF_rcpt.
IPR006770. OGF_rcpt_rpt.
[Graphical view]
PfamiPF04680. OGFr_III. 7 hits.
PF04664. OGFr_N. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning, sequencing, chromosomal location, and function of cDNAs encoding an opioid growth factor receptor (OGFr) in humans."
    Zagon I.S., Verderame M.F., Allen S.S., McLaughlin P.J.
    Brain Res. 856:75-83(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), VARIANT THR-577.
    Tissue: Placenta.
  2. "Genomic structure of human gene 7-60."
    Takanosu M., Liu J., Mayne R., Wood B.M., Brewton R.G.
    Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1), VARIANT THR-577.
  3. "The DNA sequence and comparative analysis of human chromosome 20."
    Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
    , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
    Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Skin.
  5. "Characterization of long cDNA clones from human adult spleen."
    Hattori A., Okumura K., Nagase T., Kikuno R., Hirosawa M., Ohara O.
    DNA Res. 7:357-366(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 37-677 (ISOFORM 1), VARIANT THR-577.
    Tissue: Spleen.
  6. "The biology of the opioid growth factor receptor (OGFr)."
    Zagon I.S., Verderame M.F., McLaughlin P.J.
    Brain Res. Brain Res. Rev. 38:351-376(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: REVIEW.
  7. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
    Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
    Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-315, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  8. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
    Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.
    Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  9. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-420, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic kidney.
  10. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-484, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  11. "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."
    Han G., Ye M., Zhou H., Jiang X., Feng S., Jiang X., Tian R., Wan D., Zou H., Gu J.
    Proteomics 8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-378, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.
  12. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  13. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-378, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  14. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-378, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  15. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-315; SER-361; SER-378; SER-484; SER-537; SER-557 AND SER-617, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  16. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  17. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-315 AND SER-378, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  18. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-315 AND SER-378, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.

Entry informationi

Entry nameiOGFR_HUMAN
AccessioniPrimary (citable) accession number: Q9NZT2
Secondary accession number(s): O96029
, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 2003
Last sequence update: March 6, 2007
Last modified: June 24, 2015
This is version 125 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.