Q9NZS6 (Q9NZS6_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Recommended name: Elongation factor 1-alpha RuleBase RU004060
Organism	Homo sapiens (Human) EMBL AAF36537.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	426 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. RuleBase RU000325
Sequence similarities	Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. RuleBase RU000325

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	GTP-binding RuleBase RU000323 Nucleotide-binding
Molecular function	Elongation factor RuleBase RU000325 EMBL AAF36537.1 Receptor EMBL AAF36537.1
Gene Ontology (GO)
Biological_process	GTP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	GTP binding Inferred from electronic annotation. Source: UniProtKB-KW GTPase activity Inferred from electronic annotation. Source: InterPro translation elongation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAF36537.1

Sequences

	Sequence		Length	Mass (Da)
	Q9NZS6 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 092EB842BF4BF260	FASTA	426	46,269
	10 20 30 40 50 60 GNSGKFEKEA AEMGKGSFKY AWVWDKLKAE RERGITIDIS LWKFETSKYY VTIIDAPGHR 70 80 90 100 110 120 DFIKNMITGT SQADCAVLIV AAGVGEFEAG ISKNGQTREH ALLAYTLGVK QLIVGVNKSH 130 140 150 160 170 180 STEPPYSQKR YEEIVKEVRT YIKKIGYNPD TVAFVPISGW NGDNMLEPSA NMPWFKGWKV 190 200 210 220 230 240 TRKDGNASGT TLLEALDCIL PPHSPTDKPL RLPLQDVYKI GGIGTVPVGR VETGVLKPGM 250 260 270 280 290 300 VVTFAPVNVT TEVKSVEMHH EALSEALPGD NVGFNVKNVS VKDVRRGNVA GDSKNDPPME 310 320 330 340 350 360 AAGFTAQVII LNHPGQISAG YAPVLDCHTA HIACKFAELK EKIDRRSCKK LEDGPKFLKS 370 380 390 400 410 420 GDAAIVDMVP GKPMCVESFS DYPPLGRFAV RDMRQTVAVG VIKAVDKKAA GAGKVTKSAQ KAQKAK

References

[1]	"Glucocorticoid receptor AF-1 specific elongation factor." Govindan M.V., Warriar N. Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Placenta EMBL AAF36537.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF174496 mRNA. Translation: AAF36537.1.
IPI	IPI00984414.
UniGene	Hs.535192. Hs.586423. Hs.695681.
3D structure databases
HSSP	HSSP built from PDB template 1G7C based on UniProtKB P02994.
ProteinModelPortal	Q9NZS6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9NZS6.
Proteomic databases
PRIDE	Q9NZS6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG000179.
Gene expression databases
ArrayExpress	Q9NZS6.
Family and domain databases
InterPro	IPR000795. EF_GTP-bd_dom. IPR009001. Transl_elong_EF1A/Init_IF2_C. IPR004539. Transl_elong_EF1A_euk/arc. IPR004161. Transl_elong_EFTu/EF1A_2. IPR004160. Transl_elong_EFTu/EF1A_C. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
Pfam	PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. PF03143. GTP_EFTU_D3. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
SUPFAM	SSF50465. Elong_init_C. 1 hit. SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR00483. EF-1_alpha. 1 hit.
PROSITE	PS00301. EFACTOR_GTP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9NZS6_HUMAN

Accession

Primary (citable) accession number: Q9NZS6

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	January 9, 2013
This is version 81 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.