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Q9NZN4

- EHD2_HUMAN

UniProt

Q9NZN4 - EHD2_HUMAN

Protein

EH domain-containing protein 2

Gene

EHD2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 126 (01 Oct 2014)
      Sequence version 2 (04 Jan 2005)
      Previous versions | rss
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    Functioni

    Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Required for translocation of FER1L5 to the plasma membrane. Binds ATP; does not bind GTP By similarity.By similarity

    Enzyme regulationi

    The very low intrinsic ATPase activity is increased upon interaction with liposomes.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei220 – 2201ATPBy similarity
    Binding sitei258 – 2581ATPBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi65 – 728ATPBy similarity
    Calcium bindingi494 – 50512PROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. calcium ion binding Source: InterPro
    3. GTPase activity Source: InterPro
    4. GTP binding Source: InterPro
    5. nucleic acid binding Source: ProtInc
    6. protein binding Source: UniProtKB

    GO - Biological processi

    1. blood coagulation Source: Reactome
    2. cortical actin cytoskeleton organization Source: Ensembl
    3. endocytic recycling Source: UniProtKB
    4. endocytosis Source: Ensembl
    5. positive regulation of endocytic recycling Source: UniProtKB
    6. positive regulation of myoblast fusion Source: UniProtKB
    7. protein localization to plasma membrane Source: UniProtKB

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Ligandi

    ATP-binding, Calcium, Metal-binding, Nucleotide-binding

    Enzyme and pathway databases

    ReactomeiREACT_24970. Factors involved in megakaryocyte development and platelet production.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    EH domain-containing protein 2
    Alternative name(s):
    PAST homolog 2
    Gene namesi
    Name:EHD2
    Synonyms:PAST2
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 19

    Organism-specific databases

    HGNCiHGNC:3243. EHD2.

    Subcellular locationi

    Cell membrane 1 Publication; Peripheral membrane protein 1 Publication; Cytoplasmic side 1 Publication. Endosome membrane By similarity; Peripheral membrane protein By similarity
    Note: Colocalizes with GLUT4 in intracellular tubulovesicular structures that are associated with cortical F-actin. Colocalizes with FER1L5 at plasma membrane in myoblasts and myotubes By similarity.By similarity

    GO - Cellular componenti

    1. caveola Source: MGI
    2. endosome membrane Source: Reactome
    3. extracellular vesicular exosome Source: UniProt
    4. nucleus Source: ProtInc
    5. perinuclear region of cytoplasm Source: Ensembl
    6. plasma membrane Source: UniProtKB
    7. recycling endosome membrane Source: UniProtKB

    Keywords - Cellular componenti

    Cell membrane, Endosome, Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA27678.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 543543EH domain-containing protein 2PRO_0000146111Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei438 – 4381Phosphoserine3 Publications
    Modified residuei468 – 4681Phosphoserine1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiQ9NZN4.
    PaxDbiQ9NZN4.
    PeptideAtlasiQ9NZN4.
    PRIDEiQ9NZN4.

    PTM databases

    PhosphoSiteiQ9NZN4.

    Expressioni

    Tissue specificityi

    Highly expressed in heart and moderately expressed in placenta, lung, and skeletal muscle.

    Gene expression databases

    ArrayExpressiQ9NZN4.
    BgeeiQ9NZN4.
    CleanExiHS_EHD2.
    GenevestigatoriQ9NZN4.

    Organism-specific databases

    HPAiHPA047394.

    Interactioni

    Subunit structurei

    Interacts with Asn-Pro-Phe (NPF) motifs in target proteins. Interacts with EHBP1. Interacts with FER1L5 (via second C2 domain) By similarity. Homodimer and homooligomer. Interacts with EHD1 and MYOF. May also interact with EHD3 and EHD4.By similarity2 Publications

    Protein-protein interaction databases

    BioGridi119056. 15 interactions.
    IntActiQ9NZN4. 6 interactions.
    STRINGi9606.ENSP00000263277.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9NZN4.
    SMRiQ9NZN4. Positions 1-539.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini55 – 286232Dynamin-type GAdd
    BLAST
    Domaini449 – 53789EHPROSITE-ProRule annotationAdd
    BLAST
    Domaini481 – 51636EF-handPROSITE-ProRule annotationAdd
    BLAST

    Domaini

    The EH domain interacts with Asn-Pro-Phe (NPF) motifs of target proteins.By similarity

    Sequence similaritiesi

    Contains 1 EF-hand domain.PROSITE-ProRule annotation
    Contains 1 EH domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0699.
    HOGENOMiHOG000242040.
    HOVERGENiHBG018183.
    InParanoidiQ9NZN4.
    KOiK12469.
    OMAiAPNEGKL.
    OrthoDBiEOG757CX9.
    PhylomeDBiQ9NZN4.
    TreeFamiTF314429.

    Family and domain databases

    Gene3Di1.10.238.10. 1 hit.
    3.40.50.300. 2 hits.
    InterProiIPR001401. Dynamin_GTPase.
    IPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    IPR000261. EPS15_homology.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF00350. Dynamin_N. 1 hit.
    [Graphical view]
    SMARTiSM00027. EH. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS00018. EF_HAND_1. 1 hit.
    PS50222. EF_HAND_2. 1 hit.
    PS50031. EH. 1 hit.
    PS51718. G_DYNAMIN_2. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q9NZN4-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MFSWLKRGGA RGQQPEAIRT VTSALKELYR TKLLPLEEHY RFGAFHSPAL    50
    EDADFDGKPM VLVAGQYSTG KTSFIQYLLE QEVPGSRVGP EPTTDCFVAV 100
    MHGDTEGTVP GNALVVDPDK PFRKLNPFGN TFLNRFMCAQ LPNQVLESIS 150
    IIDTPGILSG AKQRVSRGYD FPAVLRWFAE RVDLIILLFD AHKLEISDEF 200
    SEAIGALRGH EDKIRVVLNK ADMVETQQLM RVYGALMWAL GKVVGTPEVL 250
    RVYIGSFWSQ PLLVPDNRRL FELEEQDLFR DIQGLPRHAA LRKLNDLVKR 300
    ARLVRVHAYI ISYLKKEMPS VFGKENKKKQ LILKLPVIFA KIQLEHHISP 350
    GDFPDCQKMQ ELLMAHDFTK FHSLKPKLLE ALDEMLTHDI AKLMPLLRQE 400
    ELESTEVGVQ GGAFEGTHMG PFVERGPDEA MEDGEEGSDD EAEWVVTKDK 450
    SKYDEIFYNL APADGKLSGS KAKTWMVGTK LPNSVLGRIW KLSDVDRDGM 500
    LDDEEFALAS HLIEAKLEGH GLPANLPRRL VPPSKRRHKG SAE 543
    Length:543
    Mass (Da):61,161
    Last modified:January 4, 2005 - v2
    Checksum:i0EBF691B0A707359
    GO
    Isoform 2 (identifier: Q9NZN4-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-136: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:407
    Mass (Da):46,059
    Checksum:iAD3AEE6104A69366
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti96 – 961C → F in AAF40470. (PubMed:10673336)Curated
    Sequence conflicti164 – 1641R → G in AAF40470. (PubMed:10673336)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti57 – 571G → S.
    Corresponds to variant rs34140460 [ dbSNP | Ensembl ].
    VAR_033917

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 136136Missing in isoform 2. 1 PublicationVSP_056212Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF181263 mRNA. Translation: AAF40470.1.
    AF454952 mRNA. Translation: AAL51078.1.
    AK298067 mRNA. Translation: BAG60358.1.
    AK315548 mRNA. Translation: BAG37926.1.
    AC008745 Genomic DNA. No translation available.
    AC010519 Genomic DNA. No translation available.
    CH471126 Genomic DNA. Translation: EAW57505.1.
    BC014445 mRNA. Translation: AAH14445.1.
    CCDSiCCDS12704.1.
    RefSeqiNP_055416.2. NM_014601.3.
    UniGeneiHs.744963.

    Genome annotation databases

    EnsembliENST00000263277; ENSP00000263277; ENSG00000024422.
    ENST00000538399; ENSP00000439036; ENSG00000024422.
    GeneIDi30846.
    KEGGihsa:30846.
    UCSCiuc002phj.4. human.

    Polymorphism databases

    DMDMi57015322.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF181263 mRNA. Translation: AAF40470.1 .
    AF454952 mRNA. Translation: AAL51078.1 .
    AK298067 mRNA. Translation: BAG60358.1 .
    AK315548 mRNA. Translation: BAG37926.1 .
    AC008745 Genomic DNA. No translation available.
    AC010519 Genomic DNA. No translation available.
    CH471126 Genomic DNA. Translation: EAW57505.1 .
    BC014445 mRNA. Translation: AAH14445.1 .
    CCDSi CCDS12704.1.
    RefSeqi NP_055416.2. NM_014601.3.
    UniGenei Hs.744963.

    3D structure databases

    ProteinModelPortali Q9NZN4.
    SMRi Q9NZN4. Positions 1-539.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 119056. 15 interactions.
    IntActi Q9NZN4. 6 interactions.
    STRINGi 9606.ENSP00000263277.

    PTM databases

    PhosphoSitei Q9NZN4.

    Polymorphism databases

    DMDMi 57015322.

    Proteomic databases

    MaxQBi Q9NZN4.
    PaxDbi Q9NZN4.
    PeptideAtlasi Q9NZN4.
    PRIDEi Q9NZN4.

    Protocols and materials databases

    DNASUi 30846.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000263277 ; ENSP00000263277 ; ENSG00000024422 .
    ENST00000538399 ; ENSP00000439036 ; ENSG00000024422 .
    GeneIDi 30846.
    KEGGi hsa:30846.
    UCSCi uc002phj.4. human.

    Organism-specific databases

    CTDi 30846.
    GeneCardsi GC19P048216.
    HGNCi HGNC:3243. EHD2.
    HPAi HPA047394.
    MIMi 605890. gene.
    neXtProti NX_Q9NZN4.
    PharmGKBi PA27678.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG0699.
    HOGENOMi HOG000242040.
    HOVERGENi HBG018183.
    InParanoidi Q9NZN4.
    KOi K12469.
    OMAi APNEGKL.
    OrthoDBi EOG757CX9.
    PhylomeDBi Q9NZN4.
    TreeFami TF314429.

    Enzyme and pathway databases

    Reactomei REACT_24970. Factors involved in megakaryocyte development and platelet production.

    Miscellaneous databases

    ChiTaRSi EHD2. human.
    GeneWikii EHD2.
    GenomeRNAii 30846.
    NextBioi 52972.
    PROi Q9NZN4.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9NZN4.
    Bgeei Q9NZN4.
    CleanExi HS_EHD2.
    Genevestigatori Q9NZN4.

    Family and domain databases

    Gene3Di 1.10.238.10. 1 hit.
    3.40.50.300. 2 hits.
    InterProi IPR001401. Dynamin_GTPase.
    IPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    IPR000261. EPS15_homology.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF00350. Dynamin_N. 1 hit.
    [Graphical view ]
    SMARTi SM00027. EH. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS00018. EF_HAND_1. 1 hit.
    PS50222. EF_HAND_2. 1 hit.
    PS50031. EH. 1 hit.
    PS51718. G_DYNAMIN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "EHD2, EHD3, and EHD4 encode novel members of a highly conserved family of EH domain-containing proteins."
      Pohl U., Smith J.S., Tachibana I., Ueki K., Lee H.K., Ramaswamy S., Wu Q., Mohrenweiser H.W., Jenkins R.B., Louis D.N.
      Genomics 63:255-262(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
      Tissue: Fetal brain.
    2. "hEHD2, an EH domain containing protein-2."
      Benjamin S., Horowitz M.
      Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
      Tissue: Lung and Placenta.
    4. "The DNA sequence and biology of human chromosome 19."
      Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
      , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
      Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Pancreas.
    7. "Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes."
      Aboulaich N., Vainonen J.P., Stralfors P., Vener A.V.
      Biochem. J. 383:237-248(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 33-41; 168-176; 270-280 AND 342-358.
      Tissue: Adipocyte.
    8. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
      Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-438, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    9. "Shared as well as distinct roles of EHD proteins revealed by biochemical and functional comparisons in mammalian cells and C. elegans."
      George M., Ying G., Rainey M.A., Solomon A., Parikh P.T., Gao Q., Band V., Band H.
      BMC Cell Biol. 8:3-3(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, SUBCELLULAR LOCATION, SUBUNIT.
    10. "The endocytic recycling protein EHD2 interacts with myoferlin to regulate myoblast fusion."
      Doherty K.R., Demonbreun A.R., Wallace G.Q., Cave A., Posey A.D., Heretis K., Pytel P., McNally E.M.
      J. Biol. Chem. 283:20252-20260(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH MYOF.
    11. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-438 AND SER-468, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    12. "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."
      Han G., Ye M., Zhou H., Jiang X., Feng S., Jiang X., Tian R., Wan D., Zou H., Gu J.
      Proteomics 8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-438, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Liver.
    13. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    14. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiEHD2_HUMAN
    AccessioniPrimary (citable) accession number: Q9NZN4
    Secondary accession number(s): B2RDH9, B4DNU6, Q96CB6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 26, 2001
    Last sequence update: January 4, 2005
    Last modified: October 1, 2014
    This is version 126 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Human chromosome 19
      Human chromosome 19: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3