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Protein

Actin-related protein 10

Gene

ACTR10

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-HSA-2132295 MHC class II antigen presentation
R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR)
R-HSA-6798695 Neutrophil degranulation
R-HSA-6807878 COPI-mediated anterograde transport
R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic
SignaLinkiQ9NZ32

Names & Taxonomyi

Protein namesi
Recommended name:
Actin-related protein 10
Alternative name(s):
Actin-related protein 11
Short name:
hARP11
Gene namesi
Name:ACTR10
Synonyms:ACTR11, ARP11
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000131966.13
HGNCiHGNC:17372 ACTR10
neXtProtiNX_Q9NZ32

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000131966
PharmGKBiPA134899463

Polymorphism and mutation databases

BioMutaiACTR10
DMDMi27923739

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000891311 – 417Actin-related protein 10Add BLAST417

Proteomic databases

EPDiQ9NZ32
MaxQBiQ9NZ32
PaxDbiQ9NZ32
PeptideAtlasiQ9NZ32
PRIDEiQ9NZ32

PTM databases

iPTMnetiQ9NZ32
PhosphoSitePlusiQ9NZ32

Expressioni

Gene expression databases

BgeeiENSG00000131966
CleanExiHS_ACTR10
ExpressionAtlasiQ9NZ32 baseline and differential
GenevisibleiQ9NZ32 HS

Organism-specific databases

HPAiHPA071251

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
NAGKQ9UJ703EBI-2559426,EBI-372578

Protein-protein interaction databases

BioGridi120962, 50 interactors
IntActiQ9NZ32, 18 interactors
STRINGi9606.ENSP00000254286

Structurei

3D structure databases

ProteinModelPortaliQ9NZ32
SMRiQ9NZ32
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the actin family.Curated

Phylogenomic databases

eggNOGiKOG0676 Eukaryota
COG5277 LUCA
GeneTreeiENSGT00910000144250
HOGENOMiHOG000034069
HOVERGENiHBG050578
InParanoidiQ9NZ32
KOiK16576
OMAiKPIKVVQ
OrthoDBiEOG091G093E
PhylomeDBiQ9NZ32
TreeFamiTF315151

Family and domain databases

InterProiView protein in InterPro
IPR004000 Actin
IPR027127 Arp10
PANTHERiPTHR11937 PTHR11937, 1 hit
PTHR11937:SF14 PTHR11937:SF14, 1 hit
PfamiView protein in Pfam
PF00022 Actin, 1 hit
SMARTiView protein in SMART
SM00268 ACTIN, 1 hit

Sequencei

Sequence statusi: Complete.

Q9NZ32-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLYEGLGSG GEKTAVVIDL GEAFTKCGFA GETGPRCIIP SVIKRAGMPK
60 70 80 90 100
PVRVVQYNIN TEELYSYLKE FIHILYFRHL LVNPRDRRVV IIESVLCPSH
110 120 130 140 150
FRETLTRVLF KYFEVPSVLL APSHLMALLT LGINSAMVLD CGYRESLVLP
160 170 180 190 200
IYEGIPVLNC WGALPLGGKA LHKELETQLL EQCTVDTSVA KEQSLPSVMG
210 220 230 240 250
SVPEGVLEDI KARTCFVSDL KRGLKIQAAK FNIDGNNERP SPPPNVDYPL
260 270 280 290 300
DGEKILHILG SIRDSVVEIL FEQDNEEQSV ATLILDSLIQ CPIDTRKQLA
310 320 330 340 350
ENLVVIGGTS MLPGFLHRLL AEIRYLVEKP KYKKALGTKT FRIHTPPAKA
360 370 380 390 400
NCVAWLGGAI FGALQDILGS RSVSKEYYNQ TGRIPDWCSL NNPPLEMMFD
410
VGKTQPPLMK RAFSTEK
Length:417
Mass (Da):46,307
Last modified:October 1, 2000 - v1
Checksum:iDF351A7B299DB7C1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti53R → K in BAA91243 (PubMed:14702039).Curated1
Sequence conflicti93E → K in BAA91243 (PubMed:14702039).Curated1
Sequence conflicti219D → G in BAB14083 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF220190 mRNA Translation: AAF67655.1
AK000544 mRNA Translation: BAA91243.1
AK022534 mRNA Translation: BAB14083.1
BC011997 mRNA Translation: AAH11997.1
CCDSiCCDS32090.1
RefSeqiNP_060947.1, NM_018477.2
UniGeneiHs.509451

Genome annotation databases

EnsembliENST00000254286; ENSP00000254286; ENSG00000131966
GeneIDi55860
KEGGihsa:55860
UCSCiuc001xdf.4 human

Similar proteinsi

Entry informationi

Entry nameiARP10_HUMAN
AccessioniPrimary (citable) accession number: Q9NZ32
Secondary accession number(s): Q9H9Y5, Q9NWY2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 27, 2003
Last sequence update: October 1, 2000
Last modified: May 23, 2018
This is version 133 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

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