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Reviewed, UniProtKB/Swiss-Prot Q9NZ32 (ARP10_HUMAN)

Last modified November 24, 2009. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Actin-related protein 10
Alternative name(s):
    hARP11
Gene names
Name: ACTR10
Synonyms: ACTR11, ARP11
OrganismHomo sapiens (Human) [Complete proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length417 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Subcellular location

Cytoplasm › cytoskeleton By similarity.

Sequence similarities

Belongs to the actin family.

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Ontologies

Keywords
   Cellular componentCytoplasm
Cytoskeleton
   PTMPhosphoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionprotein binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 417417Actin-related protein 10
PRO_0000089131

Amino acid modifications

Modified residue4141Phosphoserine By similarity

Experimental info

Sequence conflict531R → K in BAA91243. Ref.2
Sequence conflict931E → K in BAA91243. Ref.2
Sequence conflict2191D → G in BAB14083. Ref.2

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Sequences

Sequence LengthMass (Da)Tools
Q9NZ32-1 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: DF351A7B299DB7C1

FASTA41746,307
        10         20         30         40         50         60 
MPLYEGLGSG GEKTAVVIDL GEAFTKCGFA GETGPRCIIP SVIKRAGMPK PVRVVQYNIN 

        70         80         90        100        110        120 
TEELYSYLKE FIHILYFRHL LVNPRDRRVV IIESVLCPSH FRETLTRVLF KYFEVPSVLL 

       130        140        150        160        170        180 
APSHLMALLT LGINSAMVLD CGYRESLVLP IYEGIPVLNC WGALPLGGKA LHKELETQLL 

       190        200        210        220        230        240 
EQCTVDTSVA KEQSLPSVMG SVPEGVLEDI KARTCFVSDL KRGLKIQAAK FNIDGNNERP 

       250        260        270        280        290        300 
SPPPNVDYPL DGEKILHILG SIRDSVVEIL FEQDNEEQSV ATLILDSLIQ CPIDTRKQLA 

       310        320        330        340        350        360 
ENLVVIGGTS MLPGFLHRLL AEIRYLVEKP KYKKALGTKT FRIHTPPAKA NCVAWLGGAI 

       370        380        390        400        410 
FGALQDILGS RSVSKEYYNQ TGRIPDWCSL NNPPLEMMFD VGKTQPPLMK RAFSTEK

« Hide

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References

« Hide 'large scale' references
[1]"A novel gene expressed in human hypothalamus."
Xiao H., Song H., Gao G., Ren S., Chen Z., Han Z.
Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Hypothalamus.
[2]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Ovary.
[4]Colinge J., Superti-Furga G., Bennett K.L.
Submitted (OCT-2008) to UniProtKB
Cited for: IDENTIFICATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.

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Cross-references

Sequence databases

AF220190 mRNA. Translation: AAF67655.1.
AK000544 mRNA. Translation: BAA91243.1.
AK022534 mRNA. Translation: BAB14083.1.
BC011997 mRNA. Translation: AAH11997.1.
IPIIPI00302690.
RefSeqNP_060947.1.
UniGeneHs.509451

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ9NZ32.

PTM databases

PhosphoSiteQ9NZ32.

Proteomic databases

PRIDEQ9NZ32.

Genome annotation databases

EnsemblENST00000254286; ENSP00000254286; ENSG00000131966; Homo sapiens. [Genome view]
GeneID55860.
KEGGhsa:55860.
UCSCuc001xdf.1. human.

Organism-specific databases

CTD55860.
GeneCardsGC14P057736.
HGNCHGNC:17372. ACTR10.
PharmGKBPA134899463.
GenAtlasSearch...

Phylogenomic databases

HOGENOMQ9NZ32.
HOVERGENQ9NZ32.
OMAGYRESLV
OrthoDBEOG90P6SK

Gene expression databases

ArrayExpressQ9NZ32.
BgeeQ9NZ32.
CleanExHS_ACTR10.
GenevestigatorQ9NZ32.
GermOnlineENSG00000131966. Homo sapiens.

Family and domain databases

InterProIPR004000. Actin-like.
[Graphical view]
PANTHERPTHR11937. Actin_like. 1 hit.
PfamPF00022. Actin. 1 hit.
[Graphical view]
SMARTSM00268. ACTIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio61151.

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Entry information

Entry nameARP10_HUMAN
AccessionPrimary (citable) accession number: Q9NZ32
Secondary accession number(s): Q9H9Y5, Q9NWY2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 27, 2003
Last sequence update: October 1, 2000
Last modified: November 24, 2009
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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Relevant documents

Human chromosome 14

Human chromosome 14: entries, gene names and cross-references to MIM

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents