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Q9NZ32

- ARP10_HUMAN

UniProt

Q9NZ32 - ARP10_HUMAN

Protein

Actin-related protein 10

Gene

ACTR10

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 105 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. microtubule-based movement Source: Ensembl

    Enzyme and pathway databases

    SignaLinkiQ9NZ32.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Actin-related protein 10
    Alternative name(s):
    Actin-related protein 11
    Short name:
    hARP11
    Gene namesi
    Name:ACTR10
    Synonyms:ACTR11, ARP11
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 14

    Organism-specific databases

    HGNCiHGNC:17372. ACTR10.

    Subcellular locationi

    Cytoplasmcytoskeleton By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-KW
    2. dynactin complex Source: Ensembl

    Keywords - Cellular componenti

    Cytoplasm, Cytoskeleton

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134899463.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 417417Actin-related protein 10PRO_0000089131Add
    BLAST

    Proteomic databases

    MaxQBiQ9NZ32.
    PaxDbiQ9NZ32.
    PRIDEiQ9NZ32.

    PTM databases

    PhosphoSiteiQ9NZ32.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9NZ32.
    BgeeiQ9NZ32.
    CleanExiHS_ACTR10.
    GenevestigatoriQ9NZ32.

    Interactioni

    Protein-protein interaction databases

    BioGridi120962. 13 interactions.
    IntActiQ9NZ32. 6 interactions.
    STRINGi9606.ENSP00000254286.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9NZ32.
    SMRiQ9NZ32. Positions 15-382.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the actin family.Curated

    Phylogenomic databases

    eggNOGiCOG5277.
    HOGENOMiHOG000034069.
    HOVERGENiHBG050578.
    InParanoidiQ9NZ32.
    KOiK16576.
    OMAiKPIKVVQ.
    PhylomeDBiQ9NZ32.
    TreeFamiTF315151.

    Family and domain databases

    InterProiIPR004000. Actin-related.
    IPR027127. Arp10.
    [Graphical view]
    PANTHERiPTHR11937. PTHR11937. 1 hit.
    PTHR11937:SF14. PTHR11937:SF14. 1 hit.
    PfamiPF00022. Actin. 1 hit.
    [Graphical view]
    SMARTiSM00268. ACTIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9NZ32-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPLYEGLGSG GEKTAVVIDL GEAFTKCGFA GETGPRCIIP SVIKRAGMPK    50
    PVRVVQYNIN TEELYSYLKE FIHILYFRHL LVNPRDRRVV IIESVLCPSH 100
    FRETLTRVLF KYFEVPSVLL APSHLMALLT LGINSAMVLD CGYRESLVLP 150
    IYEGIPVLNC WGALPLGGKA LHKELETQLL EQCTVDTSVA KEQSLPSVMG 200
    SVPEGVLEDI KARTCFVSDL KRGLKIQAAK FNIDGNNERP SPPPNVDYPL 250
    DGEKILHILG SIRDSVVEIL FEQDNEEQSV ATLILDSLIQ CPIDTRKQLA 300
    ENLVVIGGTS MLPGFLHRLL AEIRYLVEKP KYKKALGTKT FRIHTPPAKA 350
    NCVAWLGGAI FGALQDILGS RSVSKEYYNQ TGRIPDWCSL NNPPLEMMFD 400
    VGKTQPPLMK RAFSTEK 417
    Length:417
    Mass (Da):46,307
    Last modified:October 1, 2000 - v1
    Checksum:iDF351A7B299DB7C1
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti53 – 531R → K in BAA91243. (PubMed:14702039)Curated
    Sequence conflicti93 – 931E → K in BAA91243. (PubMed:14702039)Curated
    Sequence conflicti219 – 2191D → G in BAB14083. (PubMed:14702039)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF220190 mRNA. Translation: AAF67655.1.
    AK000544 mRNA. Translation: BAA91243.1.
    AK022534 mRNA. Translation: BAB14083.1.
    BC011997 mRNA. Translation: AAH11997.1.
    CCDSiCCDS32090.1.
    RefSeqiNP_060947.1. NM_018477.2.
    UniGeneiHs.509451.

    Genome annotation databases

    EnsembliENST00000254286; ENSP00000254286; ENSG00000131966.
    GeneIDi55860.
    KEGGihsa:55860.
    UCSCiuc001xdf.3. human.

    Polymorphism databases

    DMDMi27923739.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF220190 mRNA. Translation: AAF67655.1 .
    AK000544 mRNA. Translation: BAA91243.1 .
    AK022534 mRNA. Translation: BAB14083.1 .
    BC011997 mRNA. Translation: AAH11997.1 .
    CCDSi CCDS32090.1.
    RefSeqi NP_060947.1. NM_018477.2.
    UniGenei Hs.509451.

    3D structure databases

    ProteinModelPortali Q9NZ32.
    SMRi Q9NZ32. Positions 15-382.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 120962. 13 interactions.
    IntActi Q9NZ32. 6 interactions.
    STRINGi 9606.ENSP00000254286.

    PTM databases

    PhosphoSitei Q9NZ32.

    Polymorphism databases

    DMDMi 27923739.

    Proteomic databases

    MaxQBi Q9NZ32.
    PaxDbi Q9NZ32.
    PRIDEi Q9NZ32.

    Protocols and materials databases

    DNASUi 55860.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000254286 ; ENSP00000254286 ; ENSG00000131966 .
    GeneIDi 55860.
    KEGGi hsa:55860.
    UCSCi uc001xdf.3. human.

    Organism-specific databases

    CTDi 55860.
    GeneCardsi GC14P058666.
    HGNCi HGNC:17372. ACTR10.
    neXtProti NX_Q9NZ32.
    PharmGKBi PA134899463.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG5277.
    HOGENOMi HOG000034069.
    HOVERGENi HBG050578.
    InParanoidi Q9NZ32.
    KOi K16576.
    OMAi KPIKVVQ.
    PhylomeDBi Q9NZ32.
    TreeFami TF315151.

    Enzyme and pathway databases

    SignaLinki Q9NZ32.

    Miscellaneous databases

    GenomeRNAii 55860.
    NextBioi 61151.
    PROi Q9NZ32.

    Gene expression databases

    ArrayExpressi Q9NZ32.
    Bgeei Q9NZ32.
    CleanExi HS_ACTR10.
    Genevestigatori Q9NZ32.

    Family and domain databases

    InterProi IPR004000. Actin-related.
    IPR027127. Arp10.
    [Graphical view ]
    PANTHERi PTHR11937. PTHR11937. 1 hit.
    PTHR11937:SF14. PTHR11937:SF14. 1 hit.
    Pfami PF00022. Actin. 1 hit.
    [Graphical view ]
    SMARTi SM00268. ACTIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Hypothalamus.
    2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Ovary.
    4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiARP10_HUMAN
    AccessioniPrimary (citable) accession number: Q9NZ32
    Secondary accession number(s): Q9H9Y5, Q9NWY2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 27, 2003
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 105 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 14
      Human chromosome 14: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3