Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9NYU1

- UGGG2_HUMAN

UniProt

Q9NYU1 - UGGG2_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

UDP-glucose:glycoprotein glucosyltransferase 2

Gene

UGGT2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Display
All None

  • Function
  • Names & Taxonomy
  • Subcellular locationSubcell. location
  • Pathology & BiotechPathol./Biotech
  • PTM / Processing
  • Expression
  • Interaction
  • Structure
  • Family & Domains
  • Sequences (2)
  • Cross-references
  • Publications
  • Entry information
  • Miscellaneous
  • Similar proteins
Top

Functioni

Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation (By similarity).By similarity

Cofactori

Ca2+, Mn2+

Pathwayi

Protein modification; protein glycosylation.

GO - Molecular functioni

  1. UDP-glucose:glycoprotein glucosyltransferase activity Source: UniProtKB

GO - Biological processi

  1. cellular protein metabolic process Source: Reactome
  2. post-translational protein modification Source: Reactome
  3. protein folding Source: Reactome
  4. protein N-linked glycosylation via asparagine Source: Reactome
  5. UDP-glucosylation Source: GOC
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

ReactomeiREACT_25091. ER Quality Control Compartment (ERQC).
UniPathwayiUPA00378.

Protein family/group databases

CAZyiGT24. Glycosyltransferase Family 24.

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-glucose:glycoprotein glucosyltransferase 2 (EC:2.4.1.-)
Short name:
UGT2
Short name:
hUGT2
Alternative name(s):
UDP--Glc:glycoprotein glucosyltransferase 2
UDP-glucose ceramide glucosyltransferase-like 1
Gene namesi
Name:UGGT2
Synonyms:UGCGL2, UGT2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
ProteomesiUP000005640: Chromosome 13

Organism-specific databases

HGNCiHGNC:15664. UGGT2.

Subcellular locationi

Endoplasmic reticulum lumen 1 PublicationPROSITE-ProRule annotation. Endoplasmic reticulum-Golgi intermediate compartment 1 PublicationPROSITE-ProRule annotation

GO - Cellular componenti

  1. endoplasmic reticulum-Golgi intermediate compartment Source: UniProtKB-SubCell
  2. endoplasmic reticulum lumen Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA38015.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2727Sequence AnalysisAdd
BLAST
Chaini28 – 15161489UDP-glucose:glycoprotein glucosyltransferase 2PRO_0000012274Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi256 – 2561N-linked (GlcNAc...)Sequence Analysis
Glycosylationi286 – 2861N-linked (GlcNAc...)Sequence Analysis
Glycosylationi920 – 9201N-linked (GlcNAc...)Sequence Analysis
Glycosylationi950 – 9501N-linked (GlcNAc...)Sequence Analysis
Modified residuei1289 – 12891Phosphotyrosine1 Publication

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

MaxQBiQ9NYU1.
PaxDbiQ9NYU1.
PRIDEiQ9NYU1.

PTM databases

PhosphoSiteiQ9NYU1.

Expressioni

Tissue specificityi

Higher levels in kidney, pancreas, heart, and skeletal muscle.1 Publication

Gene expression databases

BgeeiQ9NYU1.
CleanExiHS_UGCGL2.
ExpressionAtlasiQ9NYU1. baseline and differential.
GenevestigatoriQ9NYU1.

Organism-specific databases

HPAiHPA047955.

Interactioni

Subunit structurei

Interacts with METTL23.1 Publication

Protein-protein interaction databases

BioGridi120875. 6 interactions.
IntActiQ9NYU1. 2 interactions.
STRINGi9606.ENSP00000365938.

Structurei

3D structure databases

ProteinModelPortaliQ9NYU1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1220 – 1516297GlucosyltransferaseAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi1513 – 15164Prevents secretion from ERPROSITE-ProRule annotation

Sequence similaritiesi

Belongs to the glycosyltransferase 8 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG320899.
GeneTreeiENSGT00390000004600.
HOGENOMiHOG000184622.
HOVERGENiHBG079469.
InParanoidiQ9NYU1.
KOiK11718.
OMAiFLIEGMD.
OrthoDBiEOG75J0M7.
PhylomeDBiQ9NYU1.
TreeFamiTF300320.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR002495. Glyco_trans_8.
IPR029044. Nucleotide-diphossugar_trans.
IPR009448. UDP-g_GGtrans.
[Graphical view]
PANTHERiPTHR11226. PTHR11226. 1 hit.
PfamiPF01501. Glyco_transf_8. 1 hit.
PF06427. UDP-g_GGTase. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.
PROSITEiPS00014. ER_TARGET. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9NYU1-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAPAKATNVV RLLLGSTALW LSQLGSGTVA ASKSVTAHLA AKWPETPLLL 
        60         70         80         90        100
EASEFMAEES NEKFWQFLET VQELAIYKQT ESDYSYYNLI LKKAGQFLDN 
       110        120        130        140        150
LHINLLKFAF SIRAYSPAIQ MFQQIAADEP PPDGCNAFVV IHKKHTCKIN 
       160        170        180        190        200
EIKKLLKKAA SRTRPYLFKG DHKFPTNKEN LPVVILYAEM GTRTFSAFHK 
       210        220        230        240        250
VLSEKAQNEE ILYVLRHYIQ KPSSRKMYLS GYGVELAIKS TEYKALDDTQ 
       260        270        280        290        300
VKTVTNTTVE DETETNEVQG FLFGKLKEIY SDLRDNLTAF QKYLIESNKQ 
       310        320        330        340        350
MMPLKVWELQ DLSFQAASQI MSAPVYDSIK LMKDISQNFP IKARSLTRIA 
       360        370        380        390        400
VNQHMREEIK ENQKDLQVRF KIQPGDARLF INGLRVDMDV YDAFSILDML 
       410        420        430        440        450
KLEGKMMNGL RNLGINGEDM SKFLKLNSHI WEYTYVLDIR HSSIMWINDL 
       460        470        480        490        500
ENDDLYITWP TSCQKLLKPV FPGSVPSIRR NFHNLVLFID PAQEYTLDFI 
       510        520        530        540        550
KLADVFYSHE VPLRIGFVFI LNTDDEVDGA NDAGVALWRA FNYIAEEFDI 
       560        570        580        590        600
SEAFISIVHM YQKVKKDQNI LTVDNVKSVL QNTFPHANIW DILGIHSKYD 
       610        620        630        640        650
EERKAGASFY KMTGLGPLPQ ALYNGEPFKH EEMNIKELKM AVLQRMMDAS 
       660        670        680        690        700
VYLQREVFLG TLNDRTNAID FLMDRNNVVP RINTLILRTN QQYLNLISTS 
       710        720        730        740        750
VTADVEDFST FFFLDSQDKS AVIAKNMYYL TQDDESIISA VTLWIIADFD 
       760        770        780        790        800
KPSGRKLLFN ALKHMKTSVH SRLGIIYNPT SKINEENTAI SRGILAAFLT 
       810        820        830        840        850
QKNMFLRSFL GQLAKEEIAT AIYSGDKIKT FLIEGMDKNA FEKKYNTVGV 
       860        870        880        890        900
NIFRTHQLFC QDVLKLRPGE MGIVSNGRFL GPLDEDFYAE DFYLLEKITF 
       910        920        930        940        950
SNLGEKIKGI VENMGINANN MSDFIMKVDA LMSSVPKRAS RYDVTFLREN 
       960        970        980        990       1000
HSVIKTNPQE NDMFFNVIAI VDPLTREAQK MAQLLVVLGK IINMKIKLFM 
      1010       1020       1030       1040       1050
NCRGRLSEAP LESFYRFVLE PELMSGANDV SSLGPVAKFL DIPESPLLIL 
      1060       1070       1080       1090       1100
NMITPEGWLV ETVHSNCDLD NIHLKDTEKT VTAEYELEYL LLEGQCFDKV 
      1110       1120       1130       1140       1150
TEQPPRGLQF TLGTKNKPAV VDTIVMAHHG YFQLKANPGA WILRLHQGKS 
      1160       1170       1180       1190       1200
EDIYQIVGHE GTDSQADLED IIVVLNSFKS KILKVKVKKE TDKIKEDILT 
      1210       1220       1230       1240       1250
DEDEKTKGLW DSIKSFTVSL HKENKKEKDV LNIFSVASGH LYERFLRIMM 
      1260       1270       1280       1290       1300
LSVLRNTKTP VKFWLLKNYL SPTFKEVIPH MAKEYGFRYE LVQYRWPRWL 
      1310       1320       1330       1340       1350
RQQTERQRII WGYKILFLDV LFPLAVDKII FVDADQIVRH DLKELRDFDL 
      1360       1370       1380       1390       1400
DGAPYGYTPF CDSRREMDGY RFWKTGYWAS HLLRRKYHIS ALYVVDLKKF 
      1410       1420       1430       1440       1450
RRIGAGDRLR SQYQALSQDP NSLSNLDQDL PNNMIYQVAI KSLPQDWLWC 
      1460       1470       1480       1490       1500
ETWCDDESKQ RAKTIDLCNN PKTKESKLKA AARIVPEWVE YDAEIRQLLD 
      1510 
HLENKKQDTI LTHDEL
Length:1,516
Mass (Da):174,735
Last modified:November 2, 2010 - v4
Checksum:iBD216896ECA54E4F
GO
Isoform 2 (identifier: Q9NYU1-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     278-278: E → S
     279-1516: Missing.

Note: No experimental confirmation available.

Show »
Length:278
Mass (Da):31,425
Checksum:i8B2126D4F7309389
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti323 – 3231A → T.1 Publication
Corresponds to variant rs12863903 [ dbSNP | Ensembl ].		VAR_030006
Natural varianti328 – 3281S → A.2 Publications
Corresponds to variant rs816142 [ dbSNP | Ensembl ].		VAR_030007
Natural varianti821 – 8211A → T.1 Publication
Corresponds to variant rs33949518 [ dbSNP | Ensembl ].		VAR_055849
Natural varianti865 – 8651K → R.
Corresponds to variant rs35060832 [ dbSNP | Ensembl ].		VAR_061196
Natural varianti924 – 9241F → I.
Corresponds to variant rs35780499 [ dbSNP | Ensembl ].		VAR_055850
Natural varianti994 – 9941M → L.2 Publications
Corresponds to variant rs12876018 [ dbSNP | Ensembl ].		VAR_030008
Natural varianti1274 – 12741F → L.
Corresponds to variant rs9525072 [ dbSNP | Ensembl ].		VAR_055851
Natural varianti1285 – 12851Y → F.
Corresponds to variant rs35123499 [ dbSNP | Ensembl ].		VAR_061197

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei278 – 2781E → S in isoform 2. 1 PublicationVSP_056319
Alternative sequencei279 – 15161238Missing in isoform 2. 1 PublicationVSP_056320Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF227906 mRNA. Translation: AAF66233.2.
AL136104
, AL158192, AL162500, AL607038 Genomic DNA. Translation: CAH72447.1.
AL158192
, AL136104, AL162500, AL607038 Genomic DNA. Translation: CAI13708.1.
AL607038
, AL136104, AL158192, AL162500 Genomic DNA. Translation: CAI39962.1.
AL162500
, AL136104, AL158192, AL607038 Genomic DNA. Translation: CAI40146.1.
BC032302 mRNA. Translation: AAH32302.1.
BC125233 mRNA. Translation: AAI25234.1.
AL133051 mRNA. Translation: CAB61378.1.
CCDSiCCDS9480.1. [Q9NYU1-1]
PIRiT42654.
RefSeqiNP_064506.3. NM_020121.3. [Q9NYU1-1]
UniGeneiHs.193226.
Hs.656444.

Genome annotation databases

EnsembliENST00000376714; ENSP00000365904; ENSG00000102595. [Q9NYU1-2]
ENST00000376747; ENSP00000365938; ENSG00000102595. [Q9NYU1-1]
GeneIDi55757.
KEGGihsa:55757.
UCSCiuc001vmt.3. human. [Q9NYU1-1]

Polymorphism databases

DMDMi311033544.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Web resourcesi

GGDB

GlycoGene database

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
 AF227906 mRNA. Translation: AAF66233.2 .
AL136104
, AL158192 , AL162500 , AL607038 Genomic DNA. Translation: CAH72447.1 .
AL158192
, AL136104 , AL162500 , AL607038 Genomic DNA. Translation: CAI13708.1 .
AL607038
, AL136104 , AL158192 , AL162500 Genomic DNA. Translation: CAI39962.1 .
AL162500
, AL136104 , AL158192 , AL607038 Genomic DNA. Translation: CAI40146.1 .
BC032302 mRNA. Translation: AAH32302.1 .
BC125233 mRNA. Translation: AAI25234.1 .
AL133051 mRNA. Translation: CAB61378.1 .
CCDSi CCDS9480.1. [Q9NYU1-1 ]
PIRi T42654.
RefSeqi NP_064506.3. NM_020121.3. [Q9NYU1-1 ]
UniGenei Hs.193226.
Hs.656444.

3D structure databases

ProteinModelPortali Q9NYU1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 120875. 6 interactions.
IntActi Q9NYU1. 2 interactions.
STRINGi 9606.ENSP00000365938.

Protein family/group databases

CAZyi GT24. Glycosyltransferase Family 24.

PTM databases

PhosphoSitei Q9NYU1.

Polymorphism databases

DMDMi 311033544.

Proteomic databases

MaxQBi Q9NYU1.
PaxDbi Q9NYU1.
PRIDEi Q9NYU1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000376714 ; ENSP00000365904 ; ENSG00000102595 . [Q9NYU1-2 ]
ENST00000376747 ; ENSP00000365938 ; ENSG00000102595 . [Q9NYU1-1 ]
GeneIDi 55757.
KEGGi hsa:55757.
UCSCi uc001vmt.3. human. [Q9NYU1-1 ]

Organism-specific databases

CTDi 55757.
GeneCardsi GC13M096453.
H-InvDB HIX0011410.
HGNCi HGNC:15664. UGGT2.
HPAi HPA047955.
MIMi 605898. gene.
neXtProti NX_Q9NYU1.
PharmGKBi PA38015.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG320899.
GeneTreei ENSGT00390000004600.
HOGENOMi HOG000184622.
HOVERGENi HBG079469.
InParanoidi Q9NYU1.
KOi K11718.
OMAi FLIEGMD.
OrthoDBi EOG75J0M7.
PhylomeDBi Q9NYU1.
TreeFami TF300320.

Enzyme and pathway databases

UniPathwayi UPA00378 .
Reactomei REACT_25091. ER Quality Control Compartment (ERQC).

Miscellaneous databases

ChiTaRSi UGGT2. human.
GenomeRNAii 55757.
NextBioi 60767.
PROi Q9NYU1.
SOURCEi Search...

Gene expression databases

Bgeei Q9NYU1.
CleanExi HS_UGCGL2.
ExpressionAtlasi Q9NYU1. baseline and differential.
Genevestigatori Q9NYU1.

Family and domain databases

Gene3Di 3.90.550.10. 1 hit.
InterProi IPR002495. Glyco_trans_8.
IPR029044. Nucleotide-diphossugar_trans.
IPR009448. UDP-g_GGtrans.
[Graphical view ]
PANTHERi PTHR11226. PTHR11226. 1 hit.
Pfami PF01501. Glyco_transf_8. 1 hit.
PF06427. UDP-g_GGTase. 1 hit.
[Graphical view ]
SUPFAMi SSF53448. SSF53448. 1 hit.
PROSITEi PS00014. ER_TARGET. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Two homologues encoding human UDP-glucose:glycoprotein glucosyltransferase differ in mRNA expression and enzymatic activity."
    Arnold S.M., Fessler L.I., Fessler J.H., Kaufman R.J.
    Biochemistry 39:2149-2163(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY, VARIANTS THR-323; ALA-328; THR-821 AND LEU-994.
    Tissue: Fetal liver.
  2. "The DNA sequence and analysis of human chromosome 13."
    Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L., Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S., Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P., Ambrose K.D., Andrews D.T.
    , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P., Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C., Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P., Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L., Frankish A.G., Frankland J., French L., Garner P., Garnett J., Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M., Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D., Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D., Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S., Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S., Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Beck S., Bentley D.R., Rogers J., Ross M.T.
    Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANTS ALA-328 AND LEU-994.
    Tissue: Brain.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 151-1516 (ISOFORM 1).
    Tissue: Testis.
  5. "The noncatalytic portion of human UDP-glucose: glycoprotein glucosyltransferase I confers UDP-glucose binding and transferase function to the catalytic domain."
    Arnold S.M., Kaufman R.J.
    J. Biol. Chem. 278:43320-43328(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION.
  6. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-1289, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  7. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  8. "A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity."
    Cloutier P., Lavallee-Adam M., Faubert D., Blanchette M., Coulombe B.
    PLoS Genet. 9:E1003210-E1003210(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH METTL23.
+Additional computationally mapped references.

Entry informationi

Entry nameiUGGG2_HUMAN
AccessioniPrimary (citable) accession number: Q9NYU1
Secondary accession number(s): A6NKL4
, Q08AD0, Q5JQR8, Q8N5K0, Q9UFC4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 12, 2003
Last sequence update: November 2, 2010
Last modified: January 7, 2015
This is version 122 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 13
    Human chromosome 13: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.
© 2002– 2015 UniProt Consortium | License & Disclaimer