Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9NYQ7 (CELR3_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 134. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (6) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cadherin EGF LAG seven-pass G-type receptor 3
Alternative name(s):
Cadherin family member 11
Epidermal growth factor-like protein 1
Short name=EGF-like protein 1
Flamingo homolog 1
Short name=hFmi1
Multiple epidermal growth factor-like domains protein 2
Short name=Multiple EGF-like domains protein 2
Gene names
Name:CELSR3
Synonyms:CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length3312 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Receptor that may have an important role in cell/cell signaling during nervous system formation.

Subcellular location

Cell membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.

Contains 9 cadherin domains.

Contains 8 EGF-like domains.

Contains 1 GPS domain.

Contains 1 laminin EGF-like domain.

Contains 2 laminin G-like domains.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

NCK1P163332EBI-308417,EBI-389883

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q9NYQ7-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q9NYQ7-2)

The sequence of this isoform differs from the canonical sequence as follows:
     2158-2158: G → GLRGAG
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3232 Potential
Chain33 – 33123280Cadherin EGF LAG seven-pass G-type receptor 3
PRO_0000012918

Regions

Topological domain33 – 25402508Extracellular Potential
Transmembrane2541 – 256121Helical; Name=1; Potential
Topological domain2562 – 257211Cytoplasmic Potential
Transmembrane2573 – 259321Helical; Name=2; Potential
Topological domain2594 – 26018Extracellular Potential
Transmembrane2602 – 262221Helical; Name=3; Potential
Topological domain2623 – 264321Cytoplasmic Potential
Transmembrane2644 – 266421Helical; Name=4; Potential
Topological domain2665 – 268117Extracellular Potential
Transmembrane2682 – 270221Helical; Name=5; Potential
Topological domain2703 – 272523Cytoplasmic Potential
Transmembrane2726 – 274621Helical; Name=6; Potential
Topological domain2747 – 27537Extracellular Potential
Transmembrane2754 – 277421Helical; Name=7; Potential
Topological domain2775 – 3312538Cytoplasmic Potential
Domain326 – 433108Cadherin 1
Domain434 – 545112Cadherin 2
Domain546 – 651106Cadherin 3
Domain652 – 756105Cadherin 4
Domain757 – 858102Cadherin 5
Domain859 – 961103Cadherin 6
Domain962 – 1067106Cadherin 7
Domain1068 – 1169102Cadherin 8
Domain1170 – 126596Cadherin 9
Domain1375 – 143359EGF-like 1; calcium-binding
Domain1435 – 147137EGF-like 2; calcium-binding
Domain1475 – 151440EGF-like 3; calcium-binding
Domain1515 – 1719205Laminin G-like 1
Domain1722 – 175837EGF-like 4; calcium-binding
Domain1764 – 1944181Laminin G-like 2
Domain1946 – 198237EGF-like 5; calcium-binding
Domain1983 – 202038EGF-like 6; calcium-binding
Domain2021 – 205333EGF-like 7; calcium-binding
Domain2055 – 209036EGF-like 8; calcium-binding
Domain2077 – 212448Laminin EGF-like
Domain2477 – 252953GPS

Amino acid modifications

Modified residue19631(3R)-3-hydroxyaspartate Potential
Modified residue21261Phosphotyrosine By similarity
Modified residue30511Phosphotyrosine By similarity
Modified residue30971Phosphoserine By similarity
Glycosylation6321N-linked (GlcNAc...) Potential
Glycosylation8471N-linked (GlcNAc...) Potential
Glycosylation11821N-linked (GlcNAc...) Potential
Glycosylation12221N-linked (GlcNAc...) Potential
Glycosylation13171N-linked (GlcNAc...) Potential
Glycosylation13271N-linked (GlcNAc...) Potential
Glycosylation16491N-linked (GlcNAc...) Potential
Glycosylation17131N-linked (GlcNAc...) Potential
Glycosylation17701N-linked (GlcNAc...) Potential
Glycosylation20531N-linked (GlcNAc...) Potential
Glycosylation21771N-linked (GlcNAc...) Potential
Glycosylation21961N-linked (GlcNAc...) Potential
Glycosylation23861N-linked (GlcNAc...) Potential
Glycosylation24741N-linked (GlcNAc...) Potential
Glycosylation25061N-linked (GlcNAc...) Potential
Disulfide bond1379 ↔ 1390 By similarity
Disulfide bond1384 ↔ 1421 By similarity
Disulfide bond1423 ↔ 1432 By similarity
Disulfide bond1439 ↔ 1450 By similarity
Disulfide bond1444 ↔ 1459 By similarity
Disulfide bond1461 ↔ 1470 By similarity
Disulfide bond1479 ↔ 1490 By similarity
Disulfide bond1484 ↔ 1500 By similarity
Disulfide bond1502 ↔ 1513 By similarity
Disulfide bond1693 ↔ 1719 By similarity
Disulfide bond1726 ↔ 1737 By similarity
Disulfide bond1731 ↔ 1746 By similarity
Disulfide bond1748 ↔ 1757 By similarity
Disulfide bond1915 ↔ 1944 By similarity
Disulfide bond1950 ↔ 1961 By similarity
Disulfide bond1955 ↔ 1970 By similarity
Disulfide bond1972 ↔ 1981 By similarity
Disulfide bond1985 ↔ 1996 By similarity
Disulfide bond1990 ↔ 2008 By similarity
Disulfide bond2010 ↔ 2019 By similarity
Disulfide bond2027 ↔ 2040 By similarity
Disulfide bond2042 ↔ 2052 By similarity
Disulfide bond2059 ↔ 2074 By similarity
Disulfide bond2061 ↔ 2077 By similarity
Disulfide bond2079 ↔ 2089 By similarity
Disulfide bond2098 ↔ 2107 By similarity
Disulfide bond2110 ↔ 2122 By similarity

Natural variations

Alternative sequence21581G → GLRGAG in isoform 2.
VSP_037125
Natural variant1571A → P.
Corresponds to variant rs3733085 [ dbSNP | Ensembl ].
VAR_020022
Natural variant8051S → T.
Corresponds to variant rs3821875 [ dbSNP | Ensembl ].
VAR_020023
Natural variant17581Q → R.
Corresponds to variant rs12107252 [ dbSNP | Ensembl ].
VAR_055101

Experimental info

Sequence conflict131G → E in AAF61929. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified May 5, 2009. Version 2.
Checksum: 9E6B37787A9F0348

FASTA3,312358,185
        10         20         30         40         50         60 
MMARRPPWRG LGGRSTPILL LLLLSLFPLS QEELGGGGHQ GWDPGLAATT GPRAHIGGGA 

        70         80         90        100        110        120 
LALCPESSGV REDGGPGLGV REPIFVGLRG RRQSARNSRG PPEQPNEELG IEHGVQPLGS 

       130        140        150        160        170        180 
RERETGQGPG SVLYWRPEVS SCGRTGPLQR GSLSPGALSS GVPGSGNSSP LPSDFLIRHH 

       190        200        210        220        230        240 
GPKPVSSQRN AGTGSRKRVG TARCCGELWA TGSKGQGERA TTSGAERTAP RRNCLPGASG 

       250        260        270        280        290        300 
SGPELDSAPR TARTAPASGS APRESRTAPE PAPKRMRSRG LFRCRFLPQR PGPRPPGLPA 

       310        320        330        340        350        360 
RPEARKVTSA NRARFRRAAN RHPQFPQYNY QTLVPENEAA GTAVLRVVAQ DPDAGEAGRL 

       370        380        390        400        410        420 
VYSLAALMNS RSLELFSIDP QSGLIRTAAA LDRESMERHY LRVTAQDHGS PRLSATTMVA 

       430        440        450        460        470        480 
VTVADRNDHS PVFEQAQYRE TLRENVEEGY PILQLRATDG DAPPNANLRY RFVGPPAARA 

       490        500        510        520        530        540 
AAAAAFEIDP RSGLISTSGR VDREHMESYE LVVEASDQGQ EPGPRSATVR VHITVLDEND 

       550        560        570        580        590        600 
NAPQFSEKRY VAQVREDVRP HTVVLRVTAT DRDKDANGLV HYNIISGNSR GHFAIDSLTG 

       610        620        630        640        650        660 
EIQVVAPLDF EAEREYALRI RAQDAGRPPL SNNTGLASIQ VVDINDHIPI FVSTPFQVSV 

       670        680        690        700        710        720 
LENAPLGHSV IHIQAVDADH GENARLEYSL TGVAPDTPFV INSATGWVSV SGPLDRESVE 

       730        740        750        760        770        780 
HYFFGVEARD HGSPPLSASA SVTVTVLDVN DNRPEFTMKE YHLRLNEDAA VGTSVVSVTA 

       790        800        810        820        830        840 
VDRDANSAIS YQITGGNTRN RFAISTQGGV GLVTLALPLD YKQERYFKLV LTASDRALHD 

       850        860        870        880        890        900 
HCYVHINITD ANTHRPVFQS AHYSVSVNED RPMGSTIVVI SASDDDVGEN ARITYLLEDN 

       910        920        930        940        950        960 
LPQFRIDADS GAITLQAPLD YEDQVTYTLA ITARDNGIPQ KADTTYVEVM VNDVNDNAPQ 

       970        980        990       1000       1010       1020 
FVASHYTGLV SEDAPPFTSV LQISATDRDA HANGRVQYTF QNGEDGDGDF TIEPTSGIVR 

      1030       1040       1050       1060       1070       1080 
TVRRLDREAV SVYELTAYAV DRGVPPLRTP VSIQVMVQDV NDNAPVFPAE EFEVRVKENS 

      1090       1100       1110       1120       1130       1140 
IVGSVVAQIT AVDPDEGPNA HIMYQIVEGN IPELFQMDIF SGELTALIDL DYEARQEYVI 

      1150       1160       1170       1180       1190       1200 
VVQATSAPLV SRATVHVRLV DQNDNSPVLN NFQILFNNYV SNRSDTFPSG IIGRIPAYDP 

      1210       1220       1230       1240       1250       1260 
DVSDHLFYSF ERGNELQLLV VNQTSGELRL SRKLDNNRPL VASMLVTVTD GLHSVTAQCV 

      1270       1280       1290       1300       1310       1320 
LRVVIITEEL LANSLTVRLE NMWQERFLSP LLGRFLEGVA AVLATPAEDV FIFNIQNDTD 

      1330       1340       1350       1360       1370       1380 
VGGTVLNVSF SALAPRGAGA GAAGPWFSSE ELQEQLYVRR AALAARSLLD VLPFDDNVCL 

      1390       1400       1410       1420       1430       1440 
REPCENYMKC VSVLRFDSSA PFLASASTLF RPIQPIAGLR CRCPPGFTGD FCETELDLCY 

      1450       1460       1470       1480       1490       1500 
SNPCRNGGAC ARREGGYTCV CRPRFTGEDC ELDTEAGRCV PGVCRNGGTC TDAPNGGFRC 

      1510       1520       1530       1540       1550       1560 
QCPAGGAFEG PRCEVAARSF PPSSFVMFRG LRQRFHLTLS LSFATVQQSG LLFYNGRLNE 

      1570       1580       1590       1600       1610       1620 
KHDFLALELV AGQVRLTYST GESNTVVSPT VPGGLSDGQW HTVHLRYYNK PRTDALGGAQ 

      1630       1640       1650       1660       1670       1680 
GPSKDKVAVL SVDDCDVAVA LQFGAEIGNY SCAAAGVQTS SKKSLDLTGP LLLGGVPNLP 

      1690       1700       1710       1720       1730       1740 
ENFPVSHKDF IGCMRDLHID GRRVDMAAFV ANNGTMAGCQ AKLHFCDSGP CKNSGFCSER 

      1750       1760       1770       1780       1790       1800 
WGSFSCDCPV GFGGKDCQLT MAHPHHFRGN GTLSWNFGSD MAVSVPWYLG LAFRTRATQG 

      1810       1820       1830       1840       1850       1860 
VLMQVQAGPH STLLCQLDRG LLSVTVTRGS GRASHLLLDQ VTVSDGRWHD LRLELQEEPG 

      1870       1880       1890       1900       1910       1920 
GRRGHHVLMV SLDFSLFQDT MAVGSELQGL KVKQLHVGGL PPGSAEEAPQ GLVGCIQGVW 

      1930       1940       1950       1960       1970       1980 
LGSTPSGSPA LLPPSHRVNA EPGCVVTNAC ASGPCPPHAD CRDLWQTFSC TCQPGYYGPG 

      1990       2000       2010       2020       2030       2040 
CVDACLLNPC QNQGSCRHLP GAPHGYTCDC VGGYFGHHCE HRMDQQCPRG WWGSPTCGPC 

      2050       2060       2070       2080       2090       2100 
NCDVHKGFDP NCNKTNGQCH CKEFHYRPRG SDSCLPCDCY PVGSTSRSCA PHSGQCPCRP 

      2110       2120       2130       2140       2150       2160 
GALGRQCNSC DSPFAEVTAS GCRVLYDACP KSLRSGVWWP QTKFGVLATV PCPRGALGAA 

      2170       2180       2190       2200       2210       2220 
VRLCDEAQGW LEPDLFNCTS PAFRELSLLL DGLELNKTAL DTMEAKKLAQ RLREVTGHTD 

      2230       2240       2250       2260       2270       2280 
HYFSQDVRVT ARLLAHLLAF ESHQQGFGLT ATQDAHFNEN LLWAGSALLA PETGDLWAAL 

      2290       2300       2310       2320       2330       2340 
GQRAPGGSPG SAGLVRHLEE YAATLARNME LTYLNPMGLV TPNIMLSIDR MEHPSSPRGA 

      2350       2360       2370       2380       2390       2400 
RRYPRYHSNL FRGQDAWDPH THVLLPSQSP RPSPSEVLPT SSSIENSTTS SVVPPPAPPE 

      2410       2420       2430       2440       2450       2460 
PEPGISIIIL LVYRTLGGLL PAQFQAERRG ARLPQNPVMN SPVVSVAVFH GRNFLRGILE 

      2470       2480       2490       2500       2510       2520 
SPISLEFRLL QTANRSKAIC VQWDPPGLAE QHGVWTARDC ELVHRNGSHA RCRCSRTGTF 

      2530       2540       2550       2560       2570       2580 
GVLMDASPRE RLEGDLELLA VFTHVVVAVS VAALVLTAAI LLSLRSLKSN VRGIHANVAA 

      2590       2600       2610       2620       2630       2640 
ALGVAELLFL LGIHRTHNQL VCTAVAILLH YFFLSTFAWL FVQGLHLYRM QVEPRNVDRG 

      2650       2660       2670       2680       2690       2700 
AMRFYHALGW GVPAVLLGLA VGLDPEGYGN PDFCWISVHE PLIWSFAGPV VLVIVMNGTM 

      2710       2720       2730       2740       2750       2760 
FLLAARTSCS TGQREAKKTS ALTLRSSFLL LLLVSASWLF GLLAVNHSIL AFHYLHAGLC 

      2770       2780       2790       2800       2810       2820 
GLQGLAVLLL FCVLNADARA AWMPACLGRK AAPEEARPAP GLGPGAYNNT ALFEESGLIR 

      2830       2840       2850       2860       2870       2880 
ITLGASTVSS VSSARSGRTQ DQDSQRGRSY LRDNVLVRHG SAADHTDHSL QAHAGPTDLD 

      2890       2900       2910       2920       2930       2940 
VAMFHRDAGA DSDSDSDLSL EEERSLSIPS SESEDNGRTR GRFQRPLCRA AQSERLLTHP 

      2950       2960       2970       2980       2990       3000 
KDVDGNDLLS YWPALGECEA APCALQTWGS ERRLGLDTSK DAANNNQPDP ALTSGDETSL 

      3010       3020       3030       3040       3050       3060 
GRAQRQRKGI LKNRLQYPLV PQTRGAPELS WCRAATLGHR AVPAASYGRI YAGGGTGSLS 

      3070       3080       3090       3100       3110       3120 
QPASRYSSRE QLDLLLRRQL SRERLEEAPA PVLRPLSRPG SQECMDAAPG RLEPKDRGST 

      3130       3140       3150       3160       3170       3180 
LPRRQPPRDY PGAMAGRFGS RDALDLGAPR EWLSTLPPPR RTRDLDPQPP PLPLSPQRQL 

      3190       3200       3210       3220       3230       3240 
SRDPLLPSRP LDSLSRSSNS REQLDQVPSR HPSREALGPL PQLLRAREDS VSGPSHGPST 

      3250       3260       3270       3280       3290       3300 
EQLDILSSIL ASFNSSALSS VQSSSTPLGP HTTATPSATA SVLGPSTPRS ATSHSISELS 

      3310 
PDSEVPRSEG HS 

« Hide

Isoform 2 [UniParc].

Checksum: 2E19853A04982607
Show »

FASTA3,317358,640

References

« Hide 'large scale' references
[1]"Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes."
Wu Q., Maniatis T.
Proc. Natl. Acad. Sci. U.S.A. 97:3124-3129(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
[2]"The DNA sequence, annotation and analysis of human chromosome 3."
Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J. expand/collapse author list , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening."
Nakayama M., Nakajima D., Nagase T., Nomura N., Seki N., Ohara O.
Genomics 51:27-34(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1954-3312 (ISOFORM 2).
Tissue: Brain.
[4]"A quantitative atlas of mitotic phosphorylation."
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF231023 mRNA. Translation: AAF61929.1.
AC121252 Genomic DNA. No translation available.
AB011536 mRNA. Translation: BAA32464.1.
PIRT00250.
RefSeqNP_001398.2. NM_001407.2.
UniGeneHs.631926.

3D structure databases

ProteinModelPortalQ9NYQ7.
SMRQ9NYQ7. Positions 242-1264, 1383-1853, 1950-2122, 2523-2792.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid108271. 4 interactions.
IntActQ9NYQ7. 18 interactions.
MINTMINT-1381104.
STRING9606.ENSP00000164024.

Protein family/group databases

GPCRDBSearch...

PTM databases

PhosphoSiteQ9NYQ7.

Polymorphism databases

DMDM229462826.

Proteomic databases

PaxDbQ9NYQ7.
PRIDEQ9NYQ7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000164024; ENSP00000164024; ENSG00000008300. [Q9NYQ7-1]
ENST00000544264; ENSP00000445694; ENSG00000008300. [Q9NYQ7-2]
GeneID1951.
KEGGhsa:1951.
UCSCuc003cul.3. human. [Q9NYQ7-1]

Organism-specific databases

CTD1951.
GeneCardsGC03M048673.
H-InvDBHIX0200467.
HGNCHGNC:3230. CELSR3.
MIM604264. gene.
neXtProtNX_Q9NYQ7.
PharmGKBPA26395.
HUGESearch...
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG12793.
HOGENOMHOG000231346.
HOVERGENHBG050887.
KOK04602.
OMAYRFVGPP.
OrthoDBEOG7BP81K.
PhylomeDBQ9NYQ7.
TreeFamTF323983.

Enzyme and pathway databases

SignaLinkQ9NYQ7.

Gene expression databases

ArrayExpressQ9NYQ7.
BgeeQ9NYQ7.
CleanExHS_CELSR3.
GenevestigatorQ9NYQ7.

Family and domain databases

Gene3D2.60.120.200. 2 hits.
2.60.40.60. 9 hits.
InterProIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR022624. DUF3497.
IPR000742. EG-like_dom.
IPR013032. EGF-like_CS.
IPR002049. EGF_laminin.
IPR017981. GPCR_2-like.
IPR001879. GPCR_2_extracellular_dom.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
IPR000203. GPS.
IPR001791. Laminin_G.
[Graphical view]
PfamPF00002. 7tm_2. 1 hit.
PF00028. Cadherin. 8 hits.
PF12003. DUF3497. 1 hit.
PF00008. EGF. 2 hits.
PF01825. GPS. 1 hit.
PF02793. HRM. 1 hit.
PF00053. Laminin_EGF. 1 hit.
PF02210. Laminin_G_2. 2 hits.
[Graphical view]
PRINTSPR00205. CADHERIN.
PR00249. GPCRSECRETIN.
SMARTSM00112. CA. 9 hits.
SM00181. EGF. 6 hits.
SM00180. EGF_Lam. 1 hit.
SM00303. GPS. 1 hit.
SM00008. HormR. 1 hit.
SM00282. LamG. 2 hits.
[Graphical view]
SUPFAMSSF49313. SSF49313. 9 hits.
SSF49899. SSF49899. 2 hits.
PROSITEPS00010. ASX_HYDROXYL. 1 hit.
PS00232. CADHERIN_1. 7 hits.
PS50268. CADHERIN_2. 8 hits.
PS00022. EGF_1. 6 hits.
PS01186. EGF_2. 4 hits.
PS50026. EGF_3. 6 hits.
PS01248. EGF_LAM_1. 1 hit.
PS50027. EGF_LAM_2. 1 hit.
PS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
PS50025. LAM_G_DOMAIN. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSCELSR3. human.
GeneWikiCELSR3.
GenomeRNAi1951.
NextBio7907.
PROQ9NYQ7.
SOURCESearch...

Entry information

Entry nameCELR3_HUMAN
AccessionPrimary (citable) accession number: Q9NYQ7
Secondary accession number(s): O75092
Entry history
Integrated into UniProtKB/Swiss-Prot: August 2, 2002
Last sequence update: May 5, 2009
Last modified: April 16, 2014
This is version 134 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 3

Human chromosome 3: entries, gene names and cross-references to MIM

7-transmembrane G-linked receptors

List of 7-transmembrane G-linked receptor entries