Q9NYP8 (CU062_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein C21orf62

Alternative name(s):
B37

Gene names

Name:	C21orf62
Synonyms:	C21orf120

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	219 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence caution

The sequence AAF72946.1 differs from that shown. Reason: Frameshift at position 181.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 219	219	Uncharacterized protein C21orf62		PRO_0000079524
Experimental info
	Sequence conflict	181	1	F → L in BAF83672. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q9NYP8 [UniParc]. Last modified December 15, 2009. Version 2. Checksum: C652B404ECDD86BF	FASTA	219	24,886
	10 20 30 40 50 60 MAPPSRHCLL LISTLGVFAL NCFTKGQKNS TLIFTRENTI RNCSCSADIR DCDYSLANLM 70 80 90 100 110 120 CNCKTVLPLA VERTSYNGHL TIWFTDTSAL GHLLNFTLVQ DLKLSLCSTN TLPTEYLAIC 130 140 150 160 170 180 GLKRLRINME AKHPFPEQSL LIHSGGDSDS REKPMWLHKG WQPCMYISFL DMALFNRDSA 190 200 210 FKSYSIENVT SIANNFPDFS YFRTFPMPSN KSYVVTFIY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Criteria for gene identification and features of genome organization: analysis of 6.5 Mb of DNA sequence from human chromosome 21." Slavov D., Hattori M., Sakaki Y., Rosenthal A., Shimizu N., Minoshima S., Kudoh J., Yaspo M.-L., Ramser J., Reinhardt R., Reimer C., Clancy K., Rynditch A., Gardiner K. Gene 247:215-232(2000) [PubMed: 10773462] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[3]	"The DNA sequence of human chromosome 21." Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T., Park H.-S., Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y., Soeda E., Ohki M., Takagi T., Sakaki Y., Taudien S., Blechschmidt K., Polley A. , Menzel U., Delabar J., Kumpf K., Lehmann R., Patterson D., Reichwald K., Rump A., Schillhabel M., Schudy A., Zimmermann W., Rosenthal A., Kudoh J., Shibuya K., Kawasaki K., Asakawa S., Shintani A., Sasaki T., Nagamine K., Mitsuyama S., Antonarakis S.E., Minoshima S., Shimizu N., Nordsiek G., Hornischer K., Brandt P., Scharfe M., Schoen O., Desario A., Reichelt J., Kauer G., Bloecker H., Ramser J., Beck A., Klages S., Hennig S., Riesselmann L., Dagand E., Wehrmeyer S., Borzym K., Gardiner K., Nizetic D., Francis F., Lehrach H., Reinhardt R., Yaspo M.-L. Nature 405:311-319(2000) [PubMed: 10830953] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF231922 mRNA. Translation: AAF72946.1. Frameshift. AK290983 mRNA. Translation: BAF83672.1. AP000280 Genomic DNA. No translation available.
IPI	IPI00657675.
RefSeq	NP_001155967.2. NM_001162495.2. NP_001155968.2. NM_001162496.2. NP_062542.5. NM_019596.5.
UniGene	Hs.517235.
3D structure databases
ProteinModelPortal	Q9NYP8.
ModBase	Search...
Polymorphism databases
DMDM	281371552.
Proteomic databases
PRIDE	Q9NYP8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000490358; ENSP00000418830; ENSG00000205929.
GeneID	56245.
KEGG	hsa:56245.
UCSC	uc002yqv.1. human.
Organism-specific databases
CTD	56245.
GeneCards	GC21M034163.
HGNC	HGNC:1305. C21orf62.
HPA	CAB034173. HPA016899.
neXtProt	NX_Q9NYP8.
PharmGKB	PA25857.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG19904.
GeneTree	ENSGT00390000016499.
HOVERGEN	HBG051237.
InParanoid	Q9NYP8.
OMA	YVVTFIY.
OrthoDB	EOG4NZTV5.
Gene expression databases
Bgee	Q9NYP8.
CleanEx	HS_C21orf62.
Genevestigator	Q9NYP8.
GermOnline	ENSG00000205929. Homo sapiens.
Family and domain databases
ProtoNet	Search...
Other
NextBio	61868.

Entry information

Entry name

CU062_HUMAN

Accession

Primary (citable) accession number: Q9NYP8
Secondary accession number(s): A8K4L8

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 26, 2001
Last sequence update:	December 15, 2009
Last modified:	January 25, 2012
This is version 63 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.