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Protein

Sperm protein associated with the nucleus on the X chromosome C

Gene

SPANXC

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Sperm protein associated with the nucleus on the X chromosome CCurated
Alternative name(s):
Cancer/testis antigen 11.3
Short name:
CT11.3Imported
Cancer/testis-associated protein CTp11Imported
Nuclear-associated protein SPAN-Xc
Short name:
SPANX-CImported
SPANX family member C
Gene namesi
Name:SPANXC
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome X

Organism-specific databases

HGNCiHGNC:14331. SPANXC.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: UniProtKB-SubCell
  • nucleus Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA37873.

Polymorphism and mutation databases

BioMutaiSPANXC.
DMDMi85543354.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 9797Sperm protein associated with the nucleus on the X chromosome CPRO_0000189551Add
BLAST

Proteomic databases

MaxQBiQ9NY87.
PaxDbiQ9NY87.
PRIDEiQ9NY87.

Expressioni

Tissue specificityi

Detected in testis, melanoma and bladder carcinoma.2 Publications

Developmental stagei

Detected in round and elongating spermatids.1 Publication

Gene expression databases

BgeeiQ9NY87.
CleanExiHS_SPANXC.
ExpressionAtlasiQ9NY87. baseline.
GenevisibleiQ9NY87. HS.

Organism-specific databases

HPAiHPA046423.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
SETBP1Q9Y6X03EBI-10316585,EBI-2548259

Protein-protein interaction databases

IntActiQ9NY87. 1 interaction.
STRINGi9606.ENSP00000351884.

Structurei

3D structure databases

ProteinModelPortaliQ9NY87.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi37 – 459Nuclear localization signalSequence Analysis

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi83 – 864Poly-Glu

Sequence similaritiesi

Belongs to the SPAN-X family.Curated

Phylogenomic databases

eggNOGiNOG136441.
HOGENOMiHOG000015252.
HOVERGENiHBG059401.
InParanoidiQ9NY87.
OrthoDBiEOG7N901P.
PhylomeDBiQ9NY87.
TreeFamiTF341404.

Family and domain databases

InterProiIPR010007. SPANX_prot.
[Graphical view]
PANTHERiPTHR23425. PTHR23425. 1 hit.
PfamiPF07458. SPAN-X. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9NY87-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKQSSAGGV KRSVPCDSNE ANEMMPETSS GYSDPQPAPK KLKTSESSTI
60 70 80 90
LVVRYRRNVK RTSPEELVND HARENRINPL QMEEEEFMEI MVEIPAK
Length:97
Mass (Da):10,982
Last modified:July 22, 2015 - v2
Checksum:iD253EC18FF9F8C6A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in CAB75344 (PubMed:10626816).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in CAD29839 (PubMed:12758128).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47309 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47312 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47313 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47314 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47315 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47317 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47319 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47320 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47321 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47322 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47325 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47327 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47328 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47329 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47330 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47331 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47333 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47334 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47335 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47336 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47338 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47339 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47343 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47344 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAW47346 (PubMed:16251457).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK19854 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK19856 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK19857 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK19864 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK19866 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK19868 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK19869 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK19870 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK19871 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK19872 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK19873 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK19879 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK19880 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK96948 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK96950 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK96951 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK96952 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK96953 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK96958 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK96961 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK96963 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in ABK96966 (PubMed:17373721).CuratedAdd
BLAST
Sequence conflicti17 – 3216DSNEA…TSSGY → ESNEVNETMPETPTGD in AAH54023 (PubMed:15489334).CuratedAdd
BLAST
Sequence conflicti42 – 421L → M in CAB75344 (PubMed:10626816).Curated
Sequence conflicti42 – 421L → M in CAD29839 (PubMed:12758128).Curated
Sequence conflicti42 – 421L → M in AAW47309 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47312 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47313 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47314 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47315 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47317 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47319 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47320 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47321 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47322 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47325 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47327 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47328 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47329 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47330 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47331 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47333 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47334 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47335 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47336 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47338 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47339 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47343 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47344 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in AAW47346 (PubMed:16251457).Curated
Sequence conflicti42 – 421L → M in ABK19854 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK19856 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK19857 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK19864 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK19866 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK19868 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK19869 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK19870 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK19871 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK19872 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK19873 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK19879 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK19880 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK96948 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK96950 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK96951 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK96952 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK96953 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK96958 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK96961 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK96963 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in ABK96966 (PubMed:17373721).Curated
Sequence conflicti42 – 421L → M in AAH54023 (PubMed:15489334).Curated
Sequence conflicti68 – 681V → L in CAB75344 (PubMed:10626816).Curated
Sequence conflicti68 – 681V → L in CAD29839 (PubMed:12758128).Curated
Sequence conflicti68 – 681V → L in AAW47309 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47312 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47313 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47314 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47315 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47317 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47319 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47320 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47321 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47322 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47325 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47326 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47327 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47328 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47329 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47330 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47331 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47333 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47334 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47335 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47336 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47338 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47339 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47343 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47344 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in AAW47346 (PubMed:16251457).Curated
Sequence conflicti68 – 681V → L in ABK19854 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK19856 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK19857 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK19863 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK19864 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK19866 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK19868 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK19869 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK19870 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK19871 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK19872 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK19873 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK19879 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK19880 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK96945 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK96947 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK96948 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK96950 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK96951 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK96952 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK96953 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK96958 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK96961 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK96962 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK96963 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in ABK96966 (PubMed:17373721).Curated
Sequence conflicti68 – 681V → L in AAH05382 (PubMed:15489334).Curated
Sequence conflicti68 – 681V → L in AAH54023 (PubMed:15489334).Curated
Sequence conflicti68 – 681V → L in AAH62672 (PubMed:15489334).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti59 – 591V → F.2 Publications
VAR_032024

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ238277 mRNA. Translation: CAB75344.1.
AJ457790 Genomic DNA. Translation: CAD29839.1.
AJ457792 Genomic DNA. Translation: CAD29841.1.
AJ457795 mRNA. Translation: CAD29844.1.
AY787084 Genomic DNA. Translation: AAW47309.1.
AY787086 Genomic DNA. Translation: AAW47310.1.
AY787088 Genomic DNA. Translation: AAW47312.1.
AY787089 Genomic DNA. Translation: AAW47313.1.
AY787091 Genomic DNA. Translation: AAW47314.1.
AY787093 Genomic DNA. Translation: AAW47315.1.
AY787095 Genomic DNA. Translation: AAW47317.1.
AY787096 Genomic DNA. Translation: AAW47318.1.
AY787097 Genomic DNA. Translation: AAW47319.1.
AY787098 Genomic DNA. Translation: AAW47320.1.
AY787099 Genomic DNA. Translation: AAW47321.1.
AY787100 Genomic DNA. Translation: AAW47322.1.
AY787102 Genomic DNA. Translation: AAW47324.1.
AY787103 Genomic DNA. Translation: AAW47325.1.
AY787104 Genomic DNA. Translation: AAW47326.1.
AY787105 Genomic DNA. Translation: AAW47327.1.
AY787106 Genomic DNA. Translation: AAW47328.1.
AY787107 Genomic DNA. Translation: AAW47329.1.
AY787108 Genomic DNA. Translation: AAW47330.1.
AY787109 Genomic DNA. Translation: AAW47331.1.
AY787110 Genomic DNA. Translation: AAW47332.1.
AY787111 Genomic DNA. Translation: AAW47333.1.
AY787112 Genomic DNA. Translation: AAW47334.1.
AY787113 Genomic DNA. Translation: AAW47335.1.
AY787114 Genomic DNA. Translation: AAW47336.1.
AY787116 Genomic DNA. Translation: AAW47338.1.
AY787117 Genomic DNA. Translation: AAW47339.1.
AY787119 Genomic DNA. Translation: AAW47341.1.
AY787121 Genomic DNA. Translation: AAW47343.1.
AY787122 Genomic DNA. Translation: AAW47344.1.
AY787124 Genomic DNA. Translation: AAW47346.1.
DQ994211 Genomic DNA. Translation: ABK19852.1.
DQ994213 Genomic DNA. Translation: ABK19854.1.
DQ994214 Genomic DNA. Translation: ABK19855.1.
DQ994215 Genomic DNA. Translation: ABK19856.1.
DQ994216 Genomic DNA. Translation: ABK19857.1.
DQ994217 Genomic DNA. Translation: ABK19858.1.
DQ994218 Genomic DNA. Translation: ABK19859.1.
DQ994219 Genomic DNA. Translation: ABK19860.1.
DQ994220 Genomic DNA. Translation: ABK19861.1.
DQ994222 Genomic DNA. Translation: ABK19863.1.
DQ994223 Genomic DNA. Translation: ABK19864.1.
DQ994225 Genomic DNA. Translation: ABK19866.1.
DQ994227 Genomic DNA. Translation: ABK19868.1.
DQ994228 Genomic DNA. Translation: ABK19869.1.
DQ994229 Genomic DNA. Translation: ABK19870.1.
DQ994230 Genomic DNA. Translation: ABK19871.1.
DQ994231 Genomic DNA. Translation: ABK19872.1.
DQ994232 Genomic DNA. Translation: ABK19873.1.
DQ994233 Genomic DNA. Translation: ABK19874.1.
DQ994234 Genomic DNA. Translation: ABK19875.1.
DQ994235 Genomic DNA. Translation: ABK19876.1.
DQ994238 Genomic DNA. Translation: ABK19879.1.
DQ994239 Genomic DNA. Translation: ABK19880.1.
EF101635 Genomic DNA. Translation: ABK96942.1.
EF101636 Genomic DNA. Translation: ABK96943.1.
EF101638 Genomic DNA. Translation: ABK96945.1.
EF101639 Genomic DNA. Translation: ABK96946.1.
EF101640 Genomic DNA. Translation: ABK96947.1.
EF101641 Genomic DNA. Translation: ABK96948.1.
EF101642 Genomic DNA. Translation: ABK96949.1.
EF101643 Genomic DNA. Translation: ABK96950.1.
EF101644 Genomic DNA. Translation: ABK96951.1.
EF101645 Genomic DNA. Translation: ABK96952.1.
EF101646 Genomic DNA. Translation: ABK96953.1.
EF101647 Genomic DNA. Translation: ABK96954.1.
EF101648 Genomic DNA. Translation: ABK96955.1.
EF101649 Genomic DNA. Translation: ABK96956.1.
EF101651 Genomic DNA. Translation: ABK96958.1.
EF101652 Genomic DNA. Translation: ABK96959.1.
EF101653 Genomic DNA. Translation: ABK96960.1.
EF101654 Genomic DNA. Translation: ABK96961.1.
EF101655 Genomic DNA. Translation: ABK96962.1.
EF101656 Genomic DNA. Translation: ABK96963.1.
EF101657 Genomic DNA. Translation: ABK96964.1.
EF101658 Genomic DNA. Translation: ABK96965.1.
EF101659 Genomic DNA. Translation: ABK96966.1.
AL109799 Genomic DNA. Translation: CAI41662.1.
AC234777 Genomic DNA. No translation available.
BC005382 mRNA. Translation: AAH05382.1.
BC062672 mRNA. Translation: AAH62672.1.
BC054023 mRNA. Translation: AAH54023.1.
UniGeneiHs.334464.
Hs.375036.
Hs.558533.
Hs.711784.

Genome annotation databases

EnsembliENST00000358993; ENSP00000351884; ENSG00000198573.
UCSCiuc004fbk.3. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ238277 mRNA. Translation: CAB75344.1.
AJ457790 Genomic DNA. Translation: CAD29839.1.
AJ457792 Genomic DNA. Translation: CAD29841.1.
AJ457795 mRNA. Translation: CAD29844.1.
AY787084 Genomic DNA. Translation: AAW47309.1.
AY787086 Genomic DNA. Translation: AAW47310.1.
AY787088 Genomic DNA. Translation: AAW47312.1.
AY787089 Genomic DNA. Translation: AAW47313.1.
AY787091 Genomic DNA. Translation: AAW47314.1.
AY787093 Genomic DNA. Translation: AAW47315.1.
AY787095 Genomic DNA. Translation: AAW47317.1.
AY787096 Genomic DNA. Translation: AAW47318.1.
AY787097 Genomic DNA. Translation: AAW47319.1.
AY787098 Genomic DNA. Translation: AAW47320.1.
AY787099 Genomic DNA. Translation: AAW47321.1.
AY787100 Genomic DNA. Translation: AAW47322.1.
AY787102 Genomic DNA. Translation: AAW47324.1.
AY787103 Genomic DNA. Translation: AAW47325.1.
AY787104 Genomic DNA. Translation: AAW47326.1.
AY787105 Genomic DNA. Translation: AAW47327.1.
AY787106 Genomic DNA. Translation: AAW47328.1.
AY787107 Genomic DNA. Translation: AAW47329.1.
AY787108 Genomic DNA. Translation: AAW47330.1.
AY787109 Genomic DNA. Translation: AAW47331.1.
AY787110 Genomic DNA. Translation: AAW47332.1.
AY787111 Genomic DNA. Translation: AAW47333.1.
AY787112 Genomic DNA. Translation: AAW47334.1.
AY787113 Genomic DNA. Translation: AAW47335.1.
AY787114 Genomic DNA. Translation: AAW47336.1.
AY787116 Genomic DNA. Translation: AAW47338.1.
AY787117 Genomic DNA. Translation: AAW47339.1.
AY787119 Genomic DNA. Translation: AAW47341.1.
AY787121 Genomic DNA. Translation: AAW47343.1.
AY787122 Genomic DNA. Translation: AAW47344.1.
AY787124 Genomic DNA. Translation: AAW47346.1.
DQ994211 Genomic DNA. Translation: ABK19852.1.
DQ994213 Genomic DNA. Translation: ABK19854.1.
DQ994214 Genomic DNA. Translation: ABK19855.1.
DQ994215 Genomic DNA. Translation: ABK19856.1.
DQ994216 Genomic DNA. Translation: ABK19857.1.
DQ994217 Genomic DNA. Translation: ABK19858.1.
DQ994218 Genomic DNA. Translation: ABK19859.1.
DQ994219 Genomic DNA. Translation: ABK19860.1.
DQ994220 Genomic DNA. Translation: ABK19861.1.
DQ994222 Genomic DNA. Translation: ABK19863.1.
DQ994223 Genomic DNA. Translation: ABK19864.1.
DQ994225 Genomic DNA. Translation: ABK19866.1.
DQ994227 Genomic DNA. Translation: ABK19868.1.
DQ994228 Genomic DNA. Translation: ABK19869.1.
DQ994229 Genomic DNA. Translation: ABK19870.1.
DQ994230 Genomic DNA. Translation: ABK19871.1.
DQ994231 Genomic DNA. Translation: ABK19872.1.
DQ994232 Genomic DNA. Translation: ABK19873.1.
DQ994233 Genomic DNA. Translation: ABK19874.1.
DQ994234 Genomic DNA. Translation: ABK19875.1.
DQ994235 Genomic DNA. Translation: ABK19876.1.
DQ994238 Genomic DNA. Translation: ABK19879.1.
DQ994239 Genomic DNA. Translation: ABK19880.1.
EF101635 Genomic DNA. Translation: ABK96942.1.
EF101636 Genomic DNA. Translation: ABK96943.1.
EF101638 Genomic DNA. Translation: ABK96945.1.
EF101639 Genomic DNA. Translation: ABK96946.1.
EF101640 Genomic DNA. Translation: ABK96947.1.
EF101641 Genomic DNA. Translation: ABK96948.1.
EF101642 Genomic DNA. Translation: ABK96949.1.
EF101643 Genomic DNA. Translation: ABK96950.1.
EF101644 Genomic DNA. Translation: ABK96951.1.
EF101645 Genomic DNA. Translation: ABK96952.1.
EF101646 Genomic DNA. Translation: ABK96953.1.
EF101647 Genomic DNA. Translation: ABK96954.1.
EF101648 Genomic DNA. Translation: ABK96955.1.
EF101649 Genomic DNA. Translation: ABK96956.1.
EF101651 Genomic DNA. Translation: ABK96958.1.
EF101652 Genomic DNA. Translation: ABK96959.1.
EF101653 Genomic DNA. Translation: ABK96960.1.
EF101654 Genomic DNA. Translation: ABK96961.1.
EF101655 Genomic DNA. Translation: ABK96962.1.
EF101656 Genomic DNA. Translation: ABK96963.1.
EF101657 Genomic DNA. Translation: ABK96964.1.
EF101658 Genomic DNA. Translation: ABK96965.1.
EF101659 Genomic DNA. Translation: ABK96966.1.
AL109799 Genomic DNA. Translation: CAI41662.1.
AC234777 Genomic DNA. No translation available.
BC005382 mRNA. Translation: AAH05382.1.
BC062672 mRNA. Translation: AAH62672.1.
BC054023 mRNA. Translation: AAH54023.1.
UniGeneiHs.334464.
Hs.375036.
Hs.558533.
Hs.711784.

3D structure databases

ProteinModelPortaliQ9NY87.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9NY87. 1 interaction.
STRINGi9606.ENSP00000351884.

Polymorphism and mutation databases

BioMutaiSPANXC.
DMDMi85543354.

Proteomic databases

MaxQBiQ9NY87.
PaxDbiQ9NY87.
PRIDEiQ9NY87.

Protocols and materials databases

DNASUi64663.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000358993; ENSP00000351884; ENSG00000198573.
UCSCiuc004fbk.3. human.

Organism-specific databases

GeneCardsiGC0XM140335.
HGNCiHGNC:14331. SPANXC.
HPAiHPA046423.
MIMi300330. gene.
neXtProtiNX_Q9NY87.
PharmGKBiPA37873.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG136441.
HOGENOMiHOG000015252.
HOVERGENiHBG059401.
InParanoidiQ9NY87.
OrthoDBiEOG7N901P.
PhylomeDBiQ9NY87.
TreeFamiTF341404.

Miscellaneous databases

NextBioi66601.
PROiQ9NY87.
SOURCEiSearch...

Gene expression databases

BgeeiQ9NY87.
CleanExiHS_SPANXC.
ExpressionAtlasiQ9NY87. baseline.
GenevisibleiQ9NY87. HS.

Family and domain databases

InterProiIPR010007. SPANX_prot.
[Graphical view]
PANTHERiPTHR23425. PTHR23425. 1 hit.
PfamiPF07458. SPAN-X. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "CTp11, a novel member of the family of cancer-testis antigens."
    Zendman A.J.W., Cornelissen I.M.H.A., Weidle U.H., Ruiter D.J., Van Muijen G.N.P.
    Cancer Res. 59:6223-6229(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
    Tissue: Melanoma.
  2. "The human SPANX multigene family: genomic organization, alignment and expression in male germ cells and tumor cell lines."
    Zendman A.J., Zschocke J., van Kraats A.A., de Wit N.J.W., Kurpisz M., Weidle U.H., Ruiter D.J., Weiss E.H., van Muijen G.N.P.
    Gene 309:125-133(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], DEVELOPMENTAL STAGE, TISSUE SPECIFICITY.
  3. "Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27."
    Kouprina N., Pavlicek A., Noskov V.N., Solomon G., Otstot J., Isaacs W., Carpten J.D., Trent J.M., Schleutker J., Barrett J.C., Jurka J., Larionov V.
    Genome Res. 15:1477-1486(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANT PHE-59.
  4. "Mutational analysis of SPANX genes in families with X-linked prostate cancer."
    Kouprina N., Noskov V.N., Solomon G., Otstot J., Isaacs W., Xu J., Schleutker J., Larionov V.
    Prostate 67:820-828(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANT PHE-59.
  5. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Bone marrow and Testis.

Entry informationi

Entry nameiSPNXC_HUMAN
AccessioniPrimary (citable) accession number: Q9NY87
Secondary accession number(s): Q32WL2
, Q32WL9, Q32WM0, Q5JX88, Q8TAD1, Q9BS24
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: July 22, 2015
Last modified: July 22, 2015
This is version 97 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.