Q9NX31 (CT111_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein C20orf111

Gene names

Name:	C20orf111
ORF Names:	BM-038, HSPC168, HSPC207

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	292 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence caution

The sequence AAF36127.1 differs from that shown. Reason: Frameshift at positions 201 and 195. The sequence AAF67625.1 differs from that shown. Reason: Frameshift at positions 201 and 287. The sequence BAA91191.1 differs from that shown. Reason: Frameshift at position 183.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 292	292	Uncharacterized protein C20orf111		PRO_0000079453
Regions
	Compositional bias	78 – 81	4	Poly-Arg
	Compositional bias	100 – 104	5	Poly-Ser
Natural variations
	Natural variant	74	1	V → G. Corresponds to variant rs9346 [ dbSNP | Ensembl ].		VAR_024333

Sequences

	Sequence		Length	Mass (Da)
	Q9NX31 [UniParc]. Last modified February 1, 2003. Version 2. Checksum: 4DB0FFBA241FFEF4	FASTA	292	31,779
	10 20 30 40 50 60 MKSEAKDGEE ESLQTAFKKL RVDASGSVAS LSVGEGTGVR APVRTATDDT KPKTTCASKD 70 80 90 100 110 120 SWHGSTRKSS RGAVRTQRRR RSKSPVLHPP KFIHCSTIAS SSSSQLKHKS QTDSPDGSSG 130 140 150 160 170 180 LGISSPKEFS AGESSTSLDA NHTGAVVEPL RTSVPRLPSE SKKEDSSDAT QVPQASLKAS 190 200 210 220 230 240 DLSDFQSVSK LNQGKPCTCI GKECQCKRWH DMEVYSFSGL QSVPPLAPER RSTLEDYSQS 250 260 270 280 290 LHARTLSGSP RSCSEQARVF VDDVTIEDLS GYMEYYLYIP KKMSHMAEMM YT

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells." Zhang Q.-H., Ye M., Wu X.-Y., Ren S.-X., Zhao M., Zhao C.-J., Fu G., Shen Y., Fan H.-Y., Lu G., Zhong M., Xu X.-R., Han Z.-G., Zhang J.-W., Tao J., Huang Q.-H., Zhou J., Hu G.-X. , Gu J., Chen S.-J., Chen Z. Genome Res. 10:1546-1560(2000) [PubMed: 11042152] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Bone marrow and Umbilical cord blood.
[2]	Stavrides G.S., Huckle E.J., Deloukas P. Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[3]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Gastric carcinoma and Testis.
[4]	"The DNA sequence and comparative analysis of human chromosome 20." Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E. , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J. Nature 414:865-871(2001) [PubMed: 11780052] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[6]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Skin.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF161517 mRNA. Translation: AAF29132.1. AF151041 mRNA. Translation: AAF36127.1. Frameshift. AF217514 mRNA. Translation: AAF67625.1. Frameshift. AL133000 mRNA. Translation: CAB61348.1. AK000476 mRNA. Translation: BAA91191.1. Frameshift. AK315155 mRNA. Translation: BAG37601.1. AL035447 Genomic DNA. Translation: CAB38780.1. CH471077 Genomic DNA. Translation: EAW75938.1. BC064973 mRNA. Translation: AAH64973.1.
IPI	IPI00010197.
RefSeq	NP_057554.4. NM_016470.7.
UniGene	Hs.75798.
3D structure databases
ProteinModelPortal	Q9NX31.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9NX31. 2 interactions.
PTM databases
PhosphoSite	Q9NX31.
Polymorphism databases
DMDM	28212214.
Proteomic databases
PRIDE	Q9NX31.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000255174; ENSP00000255174; ENSG00000132823. ENST00000372970; ENSP00000362061; ENSG00000132823.
GeneID	51526.
KEGG	hsa:51526.
UCSC	uc002xlk.1. human.
Organism-specific databases
CTD	51526.
GeneCards	GC20M042825.
HGNC	HGNC:16105. C20orf111.
HPA	HPA045125.
neXtProt	NX_Q9NX31.
PharmGKB	PA25651.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG09990.
GeneTree	ENSGT00390000018547.
HOGENOM	HBG717510.
HOVERGEN	HBG051188.
InParanoid	Q9NX31.
OMA	IHCSTIA.
OrthoDB	EOG4DBTFZ.
PhylomeDB	Q9NX31.
Gene expression databases
ArrayExpress	Q9NX31.
Bgee	Q9NX31.
CleanEx	HS_C20orf111.
Genevestigator	Q9NX31.
GermOnline	ENSG00000132823. Homo sapiens.
Family and domain databases
InterPro	IPR008494. DUF776. [Graphical view]
Pfam	PF05604. DUF776. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	55236.

Entry information

Entry name

CT111_HUMAN

Accession

Primary (citable) accession number: Q9NX31
Secondary accession number(s): B2RCK4 , O95912, Q9NZ84, Q9P0R8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 2003
Last sequence update:	February 1, 2003
Last modified:	January 25, 2012
This is version 79 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.