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Q9NX04

- CA109_HUMAN

UniProt

Q9NX04 - CA109_HUMAN

Protein

Uncharacterized protein C1orf109

Gene

C1orf109

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized protein C1orf109
    Gene namesi
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 1

    Organism-specific databases

    HGNCiHGNC:26039. C1orf109.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA142672493.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 203203Uncharacterized protein C1orf109PRO_0000274382Add
    BLAST

    Proteomic databases

    MaxQBiQ9NX04.
    PaxDbiQ9NX04.
    PRIDEiQ9NX04.

    PTM databases

    PhosphoSiteiQ9NX04.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9NX04.
    BgeeiQ9NX04.
    CleanExiHS_C1orf109.
    GenevestigatoriQ9NX04.

    Organism-specific databases

    HPAiHPA027110.
    HPA027127.

    Interactioni

    Protein-protein interaction databases

    BioGridi120293. 3 interactions.
    IntActiQ9NX04. 4 interactions.
    STRINGi9606.ENSP00000350704.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9NX04.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG45850.
    HOVERGENiHBG080964.
    InParanoidiQ9NX04.
    OMAiCFPVVEE.
    OrthoDBiEOG7VDXQS.
    PhylomeDBiQ9NX04.
    TreeFamiTF332524.

    Family and domain databases

    InterProiIPR029159. CK2S.
    [Graphical view]
    PfamiPF15011. CK2S. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q9NX04-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MTQDRPLLAV QEALKKCFPV VEEQQGLWQS ALRDCQPLLS SLSNLAEQLQ    50
    AAQNLRFEDV PALRAFPDLK ERLRRKQLVA GDIVLDKLGE RLAILLKVRD 100
    MVSSHVERVF QIYEQHADTV GIDAVLQPSA VSPSVADMLE WLQDIERHYR 150
    KSYLKRKYLL SSIQWGDLAN IQALPKAWDR ISKDEHQDLV QDILLNVSFF 200
    LEE 203
    Length:203
    Mass (Da):23,373
    Last modified:October 1, 2000 - v1
    Checksum:iCBD3883CB1A2C281
    GO
    Isoform 2 (identifier: Q9NX04-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         75-113: RKQLVAGDIV...SHVERVFQIY → QPSSSRCETW...ALMLSCSLQQ
         114-203: Missing.

    Show »
    Length:113
    Mass (Da):12,861
    Checksum:iC243446688C8499F
    GO

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei75 – 11339RKQLV…VFQIY → QPSSSRCETWSAAMWSECFR SMSNTQTQLALMLSCSLQQ in isoform 2. 1 PublicationVSP_022733Add
    BLAST
    Alternative sequencei114 – 20390Missing in isoform 2. 1 PublicationVSP_022734Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK000515 mRNA. Translation: BAA91221.1.
    CH471059 Genomic DNA. Translation: EAX07327.1.
    CH471059 Genomic DNA. Translation: EAX07329.1.
    CH471059 Genomic DNA. Translation: EAX07330.1.
    BC018109 mRNA. Translation: AAH18109.1.
    BC063843 mRNA. Translation: AAH63843.1.
    CCDSiCCDS423.1. [Q9NX04-1]
    RefSeqiNP_060320.1. NM_017850.1. [Q9NX04-1]
    UniGeneiHs.272673.

    Genome annotation databases

    EnsembliENST00000358011; ENSP00000350704; ENSG00000116922. [Q9NX04-1]
    ENST00000464085; ENSP00000477159; ENSG00000116922. [Q9NX04-1]
    ENST00000494120; ENSP00000477273; ENSG00000116922. [Q9NX04-2]
    GeneIDi54955.
    KEGGihsa:54955.
    UCSCiuc001cbp.3. human. [Q9NX04-1]
    uc001cbq.1. human. [Q9NX04-2]

    Polymorphism databases

    DMDMi74761780.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK000515 mRNA. Translation: BAA91221.1 .
    CH471059 Genomic DNA. Translation: EAX07327.1 .
    CH471059 Genomic DNA. Translation: EAX07329.1 .
    CH471059 Genomic DNA. Translation: EAX07330.1 .
    BC018109 mRNA. Translation: AAH18109.1 .
    BC063843 mRNA. Translation: AAH63843.1 .
    CCDSi CCDS423.1. [Q9NX04-1 ]
    RefSeqi NP_060320.1. NM_017850.1. [Q9NX04-1 ]
    UniGenei Hs.272673.

    3D structure databases

    ProteinModelPortali Q9NX04.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 120293. 3 interactions.
    IntActi Q9NX04. 4 interactions.
    STRINGi 9606.ENSP00000350704.

    PTM databases

    PhosphoSitei Q9NX04.

    Polymorphism databases

    DMDMi 74761780.

    Proteomic databases

    MaxQBi Q9NX04.
    PaxDbi Q9NX04.
    PRIDEi Q9NX04.

    Protocols and materials databases

    DNASUi 54955.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000358011 ; ENSP00000350704 ; ENSG00000116922 . [Q9NX04-1 ]
    ENST00000464085 ; ENSP00000477159 ; ENSG00000116922 . [Q9NX04-1 ]
    ENST00000494120 ; ENSP00000477273 ; ENSG00000116922 . [Q9NX04-2 ]
    GeneIDi 54955.
    KEGGi hsa:54955.
    UCSCi uc001cbp.3. human. [Q9NX04-1 ]
    uc001cbq.1. human. [Q9NX04-2 ]

    Organism-specific databases

    CTDi 54955.
    GeneCardsi GC01M038147.
    HGNCi HGNC:26039. C1orf109.
    HPAi HPA027110.
    HPA027127.
    MIMi 614799. gene.
    neXtProti NX_Q9NX04.
    PharmGKBi PA142672493.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG45850.
    HOVERGENi HBG080964.
    InParanoidi Q9NX04.
    OMAi CFPVVEE.
    OrthoDBi EOG7VDXQS.
    PhylomeDBi Q9NX04.
    TreeFami TF332524.

    Miscellaneous databases

    GeneWikii C1orf109_(gene).
    GenomeRNAii 54955.
    NextBioi 58140.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9NX04.
    Bgeei Q9NX04.
    CleanExi HS_C1orf109.
    Genevestigatori Q9NX04.

    Family and domain databases

    InterProi IPR029159. CK2S.
    [Graphical view ]
    Pfami PF15011. CK2S. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
      Tissue: Uterus.

    Entry informationi

    Entry nameiCA109_HUMAN
    AccessioniPrimary (citable) accession number: Q9NX04
    Secondary accession number(s): D3DPT1, Q8WVD1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 6, 2007
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 1
      Human chromosome 1: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

    External Data

    Dasty 3