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Protein

Transmembrane protein 160

Gene

TMEM160

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 160
Gene namesi
Name:TMEM160
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

HGNCiHGNC:26042. TMEM160.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei70 – 90HelicalSequence analysisAdd BLAST21
Transmembranei102 – 122HelicalSequence analysisAdd BLAST21
Transmembranei135 – 155HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

DisGeNETi54958.
OpenTargetsiENSG00000130748.
PharmGKBiPA145147949.

Polymorphism and mutation databases

BioMutaiTMEM160.
DMDMi74719401.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002778101 – 188Transmembrane protein 160Add BLAST188

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei48PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9NX00.
MaxQBiQ9NX00.
PaxDbiQ9NX00.
PeptideAtlasiQ9NX00.
PRIDEiQ9NX00.
TopDownProteomicsiQ9NX00.

PTM databases

iPTMnetiQ9NX00.
PhosphoSitePlusiQ9NX00.

Expressioni

Gene expression databases

BgeeiENSG00000130748.
CleanExiHS_TMEM160.
GenevisibleiQ9NX00. HS.

Organism-specific databases

HPAiHPA055904.

Interactioni

Protein-protein interaction databases

BioGridi120296. 23 interactors.
IntActiQ9NX00. 12 interactors.
STRINGi9606.ENSP00000253047.

Structurei

3D structure databases

ProteinModelPortaliQ9NX00.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TMEM160 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J0AT. Eukaryota.
ENOG4111VX5. LUCA.
GeneTreeiENSGT00390000012863.
HOGENOMiHOG000154614.
HOVERGENiHBG094062.
InParanoidiQ9NX00.
OMAiWWARVAR.
OrthoDBiEOG091G0QLF.
PhylomeDBiQ9NX00.
TreeFamiTF338764.

Family and domain databases

InterProiIPR026801. TMEM160.
[Graphical view]
PANTHERiPTHR16236. PTHR16236. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9NX00-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGGWWWARA ARLARLRFRR SLLPPQRPRS GGARGSFAPG HGPRAGASPP
60 70 80 90 100
PVSELDRADA WLLRKAHETA FLSWFRNGLL ASGIGVISFM QSDMGREAAY
110 120 130 140 150
GFFLLGGLCV VWGSASYAVG LAALRGPMQL TLGGAAVGAG AVLAASLLWA
160 170 180
CAVGLYMGQL ELDVELVPED DGTASAEGPD EAGRPPPE
Length:188
Mass (Da):19,658
Last modified:October 1, 2000 - v1
Checksum:i955BE1A693B46A28
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_030600120G → S.1 PublicationCorresponds to variant rs11083857dbSNPEnsembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK000519 mRNA. Translation: BAA91225.1.
BC002907 mRNA. Translation: AAH02907.1.
CCDSiCCDS12695.1.
RefSeqiNP_060324.1. NM_017854.1.
UniGeneiHs.105606.

Genome annotation databases

EnsembliENST00000253047; ENSP00000253047; ENSG00000130748.
GeneIDi54958.
KEGGihsa:54958.
UCSCiuc002pfz.4. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK000519 mRNA. Translation: BAA91225.1.
BC002907 mRNA. Translation: AAH02907.1.
CCDSiCCDS12695.1.
RefSeqiNP_060324.1. NM_017854.1.
UniGeneiHs.105606.

3D structure databases

ProteinModelPortaliQ9NX00.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi120296. 23 interactors.
IntActiQ9NX00. 12 interactors.
STRINGi9606.ENSP00000253047.

PTM databases

iPTMnetiQ9NX00.
PhosphoSitePlusiQ9NX00.

Polymorphism and mutation databases

BioMutaiTMEM160.
DMDMi74719401.

Proteomic databases

EPDiQ9NX00.
MaxQBiQ9NX00.
PaxDbiQ9NX00.
PeptideAtlasiQ9NX00.
PRIDEiQ9NX00.
TopDownProteomicsiQ9NX00.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000253047; ENSP00000253047; ENSG00000130748.
GeneIDi54958.
KEGGihsa:54958.
UCSCiuc002pfz.4. human.

Organism-specific databases

CTDi54958.
DisGeNETi54958.
GeneCardsiTMEM160.
HGNCiHGNC:26042. TMEM160.
HPAiHPA055904.
neXtProtiNX_Q9NX00.
OpenTargetsiENSG00000130748.
PharmGKBiPA145147949.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410J0AT. Eukaryota.
ENOG4111VX5. LUCA.
GeneTreeiENSGT00390000012863.
HOGENOMiHOG000154614.
HOVERGENiHBG094062.
InParanoidiQ9NX00.
OMAiWWARVAR.
OrthoDBiEOG091G0QLF.
PhylomeDBiQ9NX00.
TreeFamiTF338764.

Miscellaneous databases

GenomeRNAii54958.
PROiQ9NX00.

Gene expression databases

BgeeiENSG00000130748.
CleanExiHS_TMEM160.
GenevisibleiQ9NX00. HS.

Family and domain databases

InterProiIPR026801. TMEM160.
[Graphical view]
PANTHERiPTHR16236. PTHR16236. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTM160_HUMAN
AccessioniPrimary (citable) accession number: Q9NX00
Secondary accession number(s): Q9BU41
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: October 1, 2000
Last modified: November 2, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.