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Protein

Uncharacterized protein C2orf42

Gene

C2orf42

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciZFISH:ENSG00000115998-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C2orf42
Gene namesi
Name:C2orf42
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

HGNCiHGNC:26056. C2orf42.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000115998.
PharmGKBiPA147358740.

Polymorphism and mutation databases

BioMutaiC2orf42.
DMDMi74734680.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003001211 – 574Uncharacterized protein C2orf42Add BLAST574

Proteomic databases

EPDiQ9NWW7.
MaxQBiQ9NWW7.
PaxDbiQ9NWW7.
PeptideAtlasiQ9NWW7.
PRIDEiQ9NWW7.

PTM databases

iPTMnetiQ9NWW7.
PhosphoSitePlusiQ9NWW7.

Expressioni

Gene expression databases

BgeeiENSG00000115998.
ExpressionAtlasiQ9NWW7. baseline and differential.
GenevisibleiQ9NWW7. HS.

Organism-specific databases

HPAiHPA031840.
HPA031841.
HPA031842.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
ALAS1P131963EBI-2812028,EBI-3905054

Protein-protein interaction databases

BioGridi120316. 3 interactors.
IntActiQ9NWW7. 4 interactors.

Structurei

3D structure databases

ProteinModelPortaliQ9NWW7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IG2U. Eukaryota.
ENOG410YECK. LUCA.
GeneTreeiENSGT00390000011031.
HOGENOMiHOG000060318.
HOVERGENiHBG100869.
InParanoidiQ9NWW7.
OMAiVENQCQH.
OrthoDBiEOG091G058P.
PhylomeDBiQ9NWW7.
TreeFamiTF323774.

Family and domain databases

InterProiIPR026049. C2orf42.
IPR029269. Zf-tcix.
[Graphical view]
PANTHERiPTHR13518. PTHR13518. 1 hit.
PfamiPF14952. zf-tcix. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9NWW7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPNSLRTKV PAFLSDLGKA TLRGIRKCPR CGTYNGTRGL SCKNKTCGTI
60 70 80 90 100
FRYGARKQPS VEAVKIITGS DLQVYSVRQR DRGPDYRCFV ELGVSETTIQ
110 120 130 140 150
TVDGTIITQL SSGRCYVPSC LKAATQGVVE NQCQHIKLAV NCQAEATPLT
160 170 180 190 200
LKSSVLNAMQ ASPETKQTIW QLATEPTGPL VQRITKNILV VKCKASQKHS
210 220 230 240 250
LGYLHTSFVQ KVSGKSLPER RFFCSCQTLK SHKSNASKDE TAQRCIHFFA
260 270 280 290 300
CICAFASDET LAQEFSDFLN FDSSGLKEII VPQLGCHSES TVSACESTAS
310 320 330 340 350
KSKKRRKDEV SGAQMNSSLL PQDAVSSNLR KSGLKKPVVA SSLKRQACGQ
360 370 380 390 400
LLDEAQVTLS FQDWLASVTE RIHQTMHYQF DGKPEPLVFH IPQSFFDALQ
410 420 430 440 450
QRISIGSAKK RLPNSTTAFV RKDALPLGTF SKYTWHITNI LQVKQILDTP
460 470 480 490 500
EMPLEITRSF IQNRDGTYEL FKCPKVEVES IAETYGRIEK QPVLRPLELK
510 520 530 540 550
TFLKVGNTSP DQKEPTPFII EWIPDILPQS KIGELRIKFE YGHHRNGHVA
560 570
EYQDQRPPLD QPLELAPLTT ITFP
Length:574
Mass (Da):64,077
Last modified:October 1, 2000 - v1
Checksum:i53F6B0495328D7AA
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_050712314Q → P.Corresponds to variant rs3213941dbSNPEnsembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL136834 mRNA. Translation: CAB66768.1.
AK000565 mRNA. Translation: BAA91258.1.
AK026303 mRNA. Translation: BAB15438.1.
AC016700 Genomic DNA. Translation: AAX93192.1.
CH471053 Genomic DNA. Translation: EAW99830.1.
CH471053 Genomic DNA. Translation: EAW99831.1.
BC002825 mRNA. Translation: AAH02825.1.
BC005079 mRNA. Translation: AAH05079.1.
CCDSiCCDS1899.1.
RefSeqiNP_060350.1. NM_017880.1.
XP_005264446.1. XM_005264389.2.
XP_005264447.1. XM_005264390.2.
XP_005264448.1. XM_005264391.2.
XP_011531239.1. XM_011532937.2.
XP_016859887.1. XM_017004398.1.
XP_016859888.1. XM_017004399.1.
XP_016859889.1. XM_017004400.1.
UniGeneiHs.720049.

Genome annotation databases

EnsembliENST00000264434; ENSP00000264434; ENSG00000115998.
ENST00000420306; ENSP00000404515; ENSG00000115998.
GeneIDi54980.
KEGGihsa:54980.
UCSCiuc002sgh.4. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL136834 mRNA. Translation: CAB66768.1.
AK000565 mRNA. Translation: BAA91258.1.
AK026303 mRNA. Translation: BAB15438.1.
AC016700 Genomic DNA. Translation: AAX93192.1.
CH471053 Genomic DNA. Translation: EAW99830.1.
CH471053 Genomic DNA. Translation: EAW99831.1.
BC002825 mRNA. Translation: AAH02825.1.
BC005079 mRNA. Translation: AAH05079.1.
CCDSiCCDS1899.1.
RefSeqiNP_060350.1. NM_017880.1.
XP_005264446.1. XM_005264389.2.
XP_005264447.1. XM_005264390.2.
XP_005264448.1. XM_005264391.2.
XP_011531239.1. XM_011532937.2.
XP_016859887.1. XM_017004398.1.
XP_016859888.1. XM_017004399.1.
XP_016859889.1. XM_017004400.1.
UniGeneiHs.720049.

3D structure databases

ProteinModelPortaliQ9NWW7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi120316. 3 interactors.
IntActiQ9NWW7. 4 interactors.

PTM databases

iPTMnetiQ9NWW7.
PhosphoSitePlusiQ9NWW7.

Polymorphism and mutation databases

BioMutaiC2orf42.
DMDMi74734680.

Proteomic databases

EPDiQ9NWW7.
MaxQBiQ9NWW7.
PaxDbiQ9NWW7.
PeptideAtlasiQ9NWW7.
PRIDEiQ9NWW7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000264434; ENSP00000264434; ENSG00000115998.
ENST00000420306; ENSP00000404515; ENSG00000115998.
GeneIDi54980.
KEGGihsa:54980.
UCSCiuc002sgh.4. human.

Organism-specific databases

CTDi54980.
GeneCardsiC2orf42.
HGNCiHGNC:26056. C2orf42.
HPAiHPA031840.
HPA031841.
HPA031842.
neXtProtiNX_Q9NWW7.
OpenTargetsiENSG00000115998.
PharmGKBiPA147358740.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IG2U. Eukaryota.
ENOG410YECK. LUCA.
GeneTreeiENSGT00390000011031.
HOGENOMiHOG000060318.
HOVERGENiHBG100869.
InParanoidiQ9NWW7.
OMAiVENQCQH.
OrthoDBiEOG091G058P.
PhylomeDBiQ9NWW7.
TreeFamiTF323774.

Enzyme and pathway databases

BioCyciZFISH:ENSG00000115998-MONOMER.

Miscellaneous databases

GenomeRNAii54980.
PROiQ9NWW7.

Gene expression databases

BgeeiENSG00000115998.
ExpressionAtlasiQ9NWW7. baseline and differential.
GenevisibleiQ9NWW7. HS.

Family and domain databases

InterProiIPR026049. C2orf42.
IPR029269. Zf-tcix.
[Graphical view]
PANTHERiPTHR13518. PTHR13518. 1 hit.
PfamiPF14952. zf-tcix. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCB042_HUMAN
AccessioniPrimary (citable) accession number: Q9NWW7
Secondary accession number(s): D6W5G3, Q9H629
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: October 1, 2000
Last modified: November 30, 2016
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.