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Q9NWW7 (CB042_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized protein C2orf42
Gene names
Name:C2orf42
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length574 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Ontologies

Keywords
   Coding sequence diversityPolymorphism
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 574574Uncharacterized protein C2orf42
PRO_0000300121

Natural variations

Natural variant3141Q → P.
Corresponds to variant rs3213941 [ dbSNP | Ensembl ].
VAR_050712

Sequences

Sequence LengthMass (Da)Tools
Q9NWW7 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 53F6B0495328D7AA

FASTA57464,077
        10         20         30         40         50         60 
MEPNSLRTKV PAFLSDLGKA TLRGIRKCPR CGTYNGTRGL SCKNKTCGTI FRYGARKQPS 

        70         80         90        100        110        120 
VEAVKIITGS DLQVYSVRQR DRGPDYRCFV ELGVSETTIQ TVDGTIITQL SSGRCYVPSC 

       130        140        150        160        170        180 
LKAATQGVVE NQCQHIKLAV NCQAEATPLT LKSSVLNAMQ ASPETKQTIW QLATEPTGPL 

       190        200        210        220        230        240 
VQRITKNILV VKCKASQKHS LGYLHTSFVQ KVSGKSLPER RFFCSCQTLK SHKSNASKDE 

       250        260        270        280        290        300 
TAQRCIHFFA CICAFASDET LAQEFSDFLN FDSSGLKEII VPQLGCHSES TVSACESTAS 

       310        320        330        340        350        360 
KSKKRRKDEV SGAQMNSSLL PQDAVSSNLR KSGLKKPVVA SSLKRQACGQ LLDEAQVTLS 

       370        380        390        400        410        420 
FQDWLASVTE RIHQTMHYQF DGKPEPLVFH IPQSFFDALQ QRISIGSAKK RLPNSTTAFV 

       430        440        450        460        470        480 
RKDALPLGTF SKYTWHITNI LQVKQILDTP EMPLEITRSF IQNRDGTYEL FKCPKVEVES 

       490        500        510        520        530        540 
IAETYGRIEK QPVLRPLELK TFLKVGNTSP DQKEPTPFII EWIPDILPQS KIGELRIKFE 

       550        560        570 
YGHHRNGHVA EYQDQRPPLD QPLELAPLTT ITFP 

« Hide

References

[1]"Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs."
Wiemann S., Weil B., Wellenreuther R., Gassenhuber J., Glassl S., Ansorge W., Boecher M., Bloecker H., Bauersachs S., Blum H., Lauber J., Duesterhoeft A., Beyer A., Koehrer K., Strack N., Mewes H.-W., Ottenwaelder B., Obermaier B. expand/collapse author list , Tampe J., Heubner D., Wambutt R., Korn B., Klein M., Poustka A.
Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[2]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Signet-ring cell carcinoma and Small intestine.
[3]"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. expand/collapse author list , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Placenta and Skin.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL136834 mRNA. Translation: CAB66768.1.
AK000565 mRNA. Translation: BAA91258.1.
AK026303 mRNA. Translation: BAB15438.1.
AC016700 Genomic DNA. Translation: AAX93192.1.
CH471053 Genomic DNA. Translation: EAW99830.1.
CH471053 Genomic DNA. Translation: EAW99831.1.
BC002825 mRNA. Translation: AAH02825.1.
BC005079 mRNA. Translation: AAH05079.1.
CCDSCCDS1899.1.
RefSeqNP_060350.1. NM_017880.1.
XP_005264446.1. XM_005264389.1.
XP_005264447.1. XM_005264390.1.
XP_005264448.1. XM_005264391.1.
UniGeneHs.720049.

3D structure databases

ProteinModelPortalQ9NWW7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid120316. 2 interactions.
IntActQ9NWW7. 2 interactions.

PTM databases

PhosphoSiteQ9NWW7.

Polymorphism databases

DMDM74734680.

Proteomic databases

MaxQBQ9NWW7.
PaxDbQ9NWW7.
PRIDEQ9NWW7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000264434; ENSP00000264434; ENSG00000115998.
ENST00000420306; ENSP00000404515; ENSG00000115998.
GeneID54980.
KEGGhsa:54980.
UCSCuc002sgh.3. human.

Organism-specific databases

CTD54980.
GeneCardsGC02M070377.
HGNCHGNC:26056. C2orf42.
HPAHPA031841.
HPA031842.
neXtProtNX_Q9NWW7.
PharmGKBPA147358740.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG82445.
HOGENOMHOG000060318.
HOVERGENHBG100869.
InParanoidQ9NWW7.
OMAVENQCQH.
OrthoDBEOG7N8ZW0.
PhylomeDBQ9NWW7.
TreeFamTF323774.

Gene expression databases

ArrayExpressQ9NWW7.
BgeeQ9NWW7.
GenevestigatorQ9NWW7.

Family and domain databases

InterProIPR026049. C2orf42.
IPR029269. Zf-tcix.
[Graphical view]
PANTHERPTHR13518. PTHR13518. 1 hit.
PfamPF14952. zf-tcix. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi54980.
NextBio58246.

Entry information

Entry nameCB042_HUMAN
AccessionPrimary (citable) accession number: Q9NWW7
Secondary accession number(s): D6W5G3, Q9H629
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: October 1, 2000
Last modified: July 9, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 2

Human chromosome 2: entries, gene names and cross-references to MIM