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Protein

UPF0587 protein C1orf123

Gene

C1orf123

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0587 protein C1orf123
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000162384.13.
HGNCiHGNC:26059. C1orf123.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000162384.
PharmGKBiPA142672441.

Polymorphism and mutation databases

BioMutaiC1orf123.
DMDMi74753033.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002641511 – 160UPF0587 protein C1orf123Add BLAST160

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei75PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9NWV4.
MaxQBiQ9NWV4.
PaxDbiQ9NWV4.
PeptideAtlasiQ9NWV4.
PRIDEiQ9NWV4.

2D gel databases

REPRODUCTION-2DPAGEiIPI00016605.

PTM databases

iPTMnetiQ9NWV4.
PhosphoSitePlusiQ9NWV4.

Expressioni

Gene expression databases

BgeeiENSG00000162384.
CleanExiHS_C1orf123.
GenevisibleiQ9NWV4. HS.

Organism-specific databases

HPAiHPA043835.

Interactioni

Protein-protein interaction databases

BioGridi120322. 14 interactors.
IntActiQ9NWV4. 2 interactors.
MINTiMINT-3075882.
STRINGi9606.ENSP00000294360.

Structurei

3D structure databases

ProteinModelPortaliQ9NWV4.
SMRiQ9NWV4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0587 family.Curated

Phylogenomic databases

eggNOGiKOG1296. Eukaryota.
ENOG4111J9K. LUCA.
GeneTreeiENSGT00390000001523.
HOGENOMiHOG000167115.
HOVERGENiHBG058057.
InParanoidiQ9NWV4.
OMAiDWVEYDQ.
OrthoDBiEOG091G0SM9.
PhylomeDBiQ9NWV4.
TreeFamiTF105959.

Family and domain databases

InterProiView protein in InterPro
IPR008584. DUF866_euk.
PANTHERiPTHR12857. PTHR12857. 1 hit.
PfamiView protein in Pfam
PF05907. DUF866. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9NWV4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKIALQLKA TLENITNLRP VGEDFRWYLK MKCGNCGEIS DKWQYIRLMD
60 70 80 90 100
SVALKGGRGS ASMVQKCKLC ARENSIEILS STIKPYNAED NENFKTIVEF
110 120 130 140 150
ECRGLEPVDF QPQAGFAAEG VESGTAFSDI NLQEKDWTDY DEKAQESVGI
160
YEVTHQFVKC
Length:160
Mass (Da):18,048
Last modified:October 1, 2000 - v1
Checksum:i7CACEEE7CE781CBC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK000587 mRNA. Translation: BAA91272.1.
CR457246 mRNA. Translation: CAG33527.1.
AL606760 Genomic DNA. No translation available.
BC010908 mRNA. Translation: AAH10908.1.
CCDSiCCDS576.1.
RefSeqiNP_001291688.1. NM_001304759.1.
NP_001291689.1. NM_001304760.1.
NP_060357.1. NM_017887.2.
UniGeneiHs.525391.

Genome annotation databases

EnsembliENST00000294360; ENSP00000294360; ENSG00000162384.
GeneIDi54987.
KEGGihsa:54987.
UCSCiuc001cvd.4. human.

Similar proteinsi

Entry informationi

Entry nameiCA123_HUMAN
AccessioniPrimary (citable) accession number: Q9NWV4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: October 1, 2000
Last modified: September 27, 2017
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries