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Q9NVU7

- SDA1_HUMAN

UniProt

Q9NVU7 - SDA1_HUMAN

Protein

Protein SDA1 homolog

Gene

SDAD1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
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    • History
      Entry version 95 (01 Oct 2014)
      Sequence version 3 (18 May 2010)
      Previous versions | rss
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    Functioni

    Required for 60S pre-ribosomal subunits export to the cytoplasm.By similarity

    GO - Biological processi

    1. actin cytoskeleton organization Source: InterPro
    2. protein transport Source: UniProtKB-KW
    3. ribosomal large subunit biogenesis Source: UniProtKB
    4. ribosomal large subunit export from nucleus Source: InterPro

    Keywords - Biological processi

    Protein transport, Ribosome biogenesis, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein SDA1 homolog
    Alternative name(s):
    Nucleolar protein 130
    SDA1 domain-containing protein 1
    Short name:
    hSDA
    Gene namesi
    Name:SDAD1
    Synonyms:NUC130
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 4

    Organism-specific databases

    HGNCiHGNC:25537. SDAD1.

    Subcellular locationi

    Nucleusnucleolus 2 Publications

    GO - Cellular componenti

    1. nucleolus Source: UniProtKB

    Keywords - Cellular componenti

    Nucleus

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134961441.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 687687Protein SDA1 homologPRO_0000287482Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei232 – 2321Phosphoserine2 Publications
    Modified residuei234 – 2341Phosphoserine2 Publications
    Modified residuei236 – 2361Phosphoserine2 Publications
    Modified residuei585 – 5851Phosphoserine6 Publications
    Modified residuei595 – 5951Phosphoserine1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiQ9NVU7.
    PaxDbiQ9NVU7.
    PeptideAtlasiQ9NVU7.
    PRIDEiQ9NVU7.

    PTM databases

    PhosphoSiteiQ9NVU7.

    Expressioni

    Tissue specificityi

    Highly expressed in testis, kidney, spleen, brain and fetal tissues. Also expressed at lower level in heart, lung, liver, small intestine, ovary, uterus, mammary gland and placenta.2 Publications

    Gene expression databases

    ArrayExpressiQ9NVU7.
    BgeeiQ9NVU7.
    CleanExiHS_SDAD1.
    GenevestigatoriQ9NVU7.

    Organism-specific databases

    HPAiHPA035949.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    TGIF1Q155831EBI-1043768,EBI-714215

    Protein-protein interaction databases

    BioGridi120456. 9 interactions.
    IntActiQ9NVU7. 4 interactions.
    MINTiMINT-4994740.
    STRINGi9606.ENSP00000348596.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9NVU7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili253 – 31563Sequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Belongs to the SDA1 family.Curated

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiNOG292808.
    HOGENOMiHOG000204601.
    HOVERGENiHBG059552.
    InParanoidiQ9NVU7.
    KOiK14856.
    OMAiQVAQCYP.
    OrthoDBiEOG7QG43K.
    PhylomeDBiQ9NVU7.
    TreeFamiTF105727.

    Family and domain databases

    InterProiIPR016024. ARM-type_fold.
    IPR027312. Sda1.
    IPR007949. SDA1_dom.
    IPR012977. Uncharacterised_NUC130/133_N.
    [Graphical view]
    PANTHERiPTHR12730:SF0. PTHR12730:SF0. 1 hit.
    PfamiPF08158. NUC130_3NT. 1 hit.
    PF05285. SDA1. 1 hit.
    [Graphical view]
    SUPFAMiSSF48371. SSF48371. 2 hits.

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q9NVU7-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MSNRNNNKLP SNLPQLQNLI KRDPPAYIEE FLQQYNHYKS NVEIFKLQPN    50
    KPSKELAELV MFMAQISHCY PEYLSNFPQE VKDLLSCNHT VLDPDLRMTF 100
    CKALILLRNK NLINPSSLLE LFFELFRCHD KLLRKTLYTH IVTDIKNINA 150
    KHKNNKVNVV LQNFMYTMLR DSNATAAKMS LDVMIELYRR NIWNDAKTVN 200
    VITTACFSKV TKILVAALTF FLGKDEDEKQ DSDSESEDDG PTARDLLVQY 250
    ATGKKSSKNK KKLEKAMKVL KKQKKKKKPE VFNFSAIHLI HDPQDFAEKL 300
    LKQLECCKER FEVKMMLMNL ISRLVGIHEL FLFNFYPFLQ RFLQPHQREV 350
    TKILLFAAQA SHHLVPPEII QSLLMTVANN FVTDKNSGEV MTVGINAIKE 400
    ITARCPLAMT EELLQDLAQY KTHKDKNVMM SARTLIHLFR TLNPQMLQKK 450
    FRGKPTEASI EARVQEYGEL DAKDYIPGAE VLEVEKEENA ENDEDGWEST 500
    SLSEEEDADG EWIDVQHSSD EEQQEISKKL NSMPMEERKA KAAAISTSRV 550
    LTQEDFQKIR MAQMRKELDA APGKSQKRKY IEIDSDEEPR GELLSLRDIE 600
    RLHKKPKSDK ETRLATAMAG KTDRKEFVRK KTKTNPFSSS TNKEKKKQKN 650
    FMMMRYSQNV RSKNKRSFRE KQLALRDALL KKRKRMK 687
    Length:687
    Mass (Da):79,871
    Last modified:May 18, 2010 - v3
    Checksum:iB01EE09383EA959C
    GO
    Isoform 2 (identifier: Q9NVU7-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-97: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:590
    Mass (Da):68,455
    Checksum:i06780B225C43F041
    GO

    Sequence cautioni

    The sequence AAI07896.1 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence.
    The sequence BAA91648.1 differs from that shown. Reason: Frameshift at position 53.
    The sequence BAB14177.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
    The sequence BAB14790.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti186 – 1861E → G in CAH18368. (PubMed:17974005)Curated
    Sequence conflicti288 – 2881H → L in BAA91648. (PubMed:14702039)Curated
    Sequence conflicti319 – 3191N → S in CAH18368. (PubMed:17974005)Curated
    Sequence conflicti396 – 3961N → S in CAH18368. (PubMed:17974005)Curated
    Sequence conflicti617 – 6171A → S in BAB14177. (PubMed:14702039)Curated
    Sequence conflicti634 – 6341T → A in CAH18368. (PubMed:17974005)Curated
    Sequence conflicti651 – 6511F → L in CAH18368. (PubMed:17974005)Curated

    Polymorphismi

    Variations in SDAD1 may be a cause of susceptibility to seasonal allergic rhinitis (SAR). SAR is a common allergic disorder characterized by episodes of sneezing, rhinorrhea, and swelling of the nasal mucosa.

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti258 – 2581K → Q.
    Corresponds to variant rs15481 [ dbSNP | Ensembl ].
    VAR_032312
    Natural varianti490 – 4901A → D.
    Corresponds to variant rs34627298 [ dbSNP | Ensembl ].
    VAR_032313
    Natural varianti575 – 5751S → C.2 Publications
    Corresponds to variant rs2242471 [ dbSNP | Ensembl ].
    VAR_032314
    Natural varianti660 – 6601V → I.
    Corresponds to variant rs17001276 [ dbSNP | Ensembl ].
    VAR_032315

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 9797Missing in isoform 2. 1 PublicationVSP_025505Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR749574 mRNA. Translation: CAH18368.1.
    AC110615 Genomic DNA. No translation available.
    AC112719 Genomic DNA. No translation available.
    AC115628 Genomic DNA. No translation available.
    BC054040 mRNA. Translation: AAH54040.1.
    BC063797 mRNA. Translation: AAH63797.1.
    BC107895 mRNA. Translation: AAI07896.1. Sequence problems.
    AK001360 mRNA. Translation: BAA91648.1. Frameshift.
    AK022683 mRNA. Translation: BAB14177.1. Different initiation.
    AK024031 mRNA. Translation: BAB14790.1. Different initiation.
    CCDSiCCDS3573.2. [Q9NVU7-1]
    RefSeqiNP_001275912.1. NM_001288983.1.
    NP_001275913.1. NM_001288984.1. [Q9NVU7-2]
    NP_060585.2. NM_018115.3. [Q9NVU7-1]
    XP_005263162.1. XM_005263105.2. [Q9NVU7-2]
    UniGeneiHs.632604.

    Genome annotation databases

    EnsembliENST00000356260; ENSP00000348596; ENSG00000198301. [Q9NVU7-1]
    GeneIDi55153.
    KEGGihsa:55153.
    UCSCiuc003hje.4. human. [Q9NVU7-1]

    Polymorphism databases

    DMDMi296452964.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR749574 mRNA. Translation: CAH18368.1 .
    AC110615 Genomic DNA. No translation available.
    AC112719 Genomic DNA. No translation available.
    AC115628 Genomic DNA. No translation available.
    BC054040 mRNA. Translation: AAH54040.1 .
    BC063797 mRNA. Translation: AAH63797.1 .
    BC107895 mRNA. Translation: AAI07896.1 . Sequence problems.
    AK001360 mRNA. Translation: BAA91648.1 . Frameshift.
    AK022683 mRNA. Translation: BAB14177.1 . Different initiation.
    AK024031 mRNA. Translation: BAB14790.1 . Different initiation.
    CCDSi CCDS3573.2. [Q9NVU7-1 ]
    RefSeqi NP_001275912.1. NM_001288983.1.
    NP_001275913.1. NM_001288984.1. [Q9NVU7-2 ]
    NP_060585.2. NM_018115.3. [Q9NVU7-1 ]
    XP_005263162.1. XM_005263105.2. [Q9NVU7-2 ]
    UniGenei Hs.632604.

    3D structure databases

    ProteinModelPortali Q9NVU7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 120456. 9 interactions.
    IntActi Q9NVU7. 4 interactions.
    MINTi MINT-4994740.
    STRINGi 9606.ENSP00000348596.

    PTM databases

    PhosphoSitei Q9NVU7.

    Polymorphism databases

    DMDMi 296452964.

    Proteomic databases

    MaxQBi Q9NVU7.
    PaxDbi Q9NVU7.
    PeptideAtlasi Q9NVU7.
    PRIDEi Q9NVU7.

    Protocols and materials databases

    DNASUi 55153.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000356260 ; ENSP00000348596 ; ENSG00000198301 . [Q9NVU7-1 ]
    GeneIDi 55153.
    KEGGi hsa:55153.
    UCSCi uc003hje.4. human. [Q9NVU7-1 ]

    Organism-specific databases

    CTDi 55153.
    GeneCardsi GC04M076871.
    H-InvDB HIX0025559.
    HGNCi HGNC:25537. SDAD1.
    HPAi HPA035949.
    neXtProti NX_Q9NVU7.
    PharmGKBi PA134961441.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG292808.
    HOGENOMi HOG000204601.
    HOVERGENi HBG059552.
    InParanoidi Q9NVU7.
    KOi K14856.
    OMAi QVAQCYP.
    OrthoDBi EOG7QG43K.
    PhylomeDBi Q9NVU7.
    TreeFami TF105727.

    Miscellaneous databases

    GeneWikii SDAD1.
    GenomeRNAii 55153.
    NextBioi 58895.
    PROi Q9NVU7.

    Gene expression databases

    ArrayExpressi Q9NVU7.
    Bgeei Q9NVU7.
    CleanExi HS_SDAD1.
    Genevestigatori Q9NVU7.

    Family and domain databases

    InterProi IPR016024. ARM-type_fold.
    IPR027312. Sda1.
    IPR007949. SDA1_dom.
    IPR012977. Uncharacterised_NUC130/133_N.
    [Graphical view ]
    PANTHERi PTHR12730:SF0. PTHR12730:SF0. 1 hit.
    Pfami PF08158. NUC130_3NT. 1 hit.
    PF05285. SDA1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48371. SSF48371. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), VARIANT CYS-575.
      Tissue: Rectum tumor.
    2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-277 (ISOFORM 1).
      Tissue: PNS and Uterus.
    4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 50-687 (ISOFORM 1), VARIANT CYS-575.
    5. Cited for: SUBCELLULAR LOCATION.
    6. "Expression and localization studies of hSDA, the human ortholog of the yeast SDA1 gene."
      Babbio F., Farinacci M., Saracino F., Carbone M.L., Privitera E.
      Cell Cycle 3:486-490(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
    7. "Identification and characterization of RNA sequences to which human PUMILIO-2 (PUM2) and deleted in Azoospermia-like (DAZL) bind."
      Fox M., Urano J., Reijo Pera R.A.
      Genomics 85:92-105(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: TISSUE SPECIFICITY.
    8. "Association of a haplotype block spanning SDAD1 gene and CXC chemokine genes with allergic rhinitis."
      Zhang J., Noguchi E., Migita O., Yokouchi Y., Nakayama J., Shibasaki M., Arinami T.
      J. Allergy Clin. Immunol. 115:548-554(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: POLYMORPHISM.
    9. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
      Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-585, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    10. "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
      Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D., Yates J.R. III
      J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-585, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    11. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M.
      Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-585, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    12. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-232; SER-234; SER-236 AND SER-585, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    13. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
      Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    14. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-585, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    15. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    16. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-232; SER-234; SER-236; SER-585 AND SER-595, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiSDA1_HUMAN
    AccessioniPrimary (citable) accession number: Q9NVU7
    Secondary accession number(s): Q32Q11
    , Q68D52, Q7Z5U4, Q9H831, Q9H9P6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 15, 2007
    Last sequence update: May 18, 2010
    Last modified: October 1, 2014
    This is version 95 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Miscellaneous

    DAZL and PUM2 bind its 3'-UTR mRNA, suggesting that these proteins may regulate its translation.

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 4
      Human chromosome 4: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3