Reviewed, UniProtKB/Swiss-Prot Q9NVT9 (ARMC1_HUMAN)

Names and origin

Protein names

Recommended name:
    Armadillo repeat-containing protein 1

Gene names

Name:	ARMC1
Synonyms:	ARCP

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	282 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Contains 1 ARM repeat.

Ontologies

Keywords
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metal ion transport Inferred from electronic annotation. Source: InterPro
Molecular function	metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 282	282	Armadillo repeat-containing protein 1		PRO_0000240882
Regions
	Repeat	39 – 81	43	ARM
Amino acid modifications
	Modified residue	260	1	Phosphoserine

Sequences

	Sequence		Length	Mass (Da)
	Q9NVT9-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 9CDF2DCFEC6C3A08	FASTA	282	31,281
	10 20 30 40 50 60 MNSSTSTMSE EPDALSVVNQ LRDLAADPLN RRAIVQDQGC LPGLILFMDH PNPPVVHSAL 70 80 90 100 110 120 LALRYLAECR ANREKMKGEL GMMLSLQNVI QKTTTPGETK LLASEIYDIL QSSNMADGDS 130 140 150 160 170 180 FNEMNSRRRK AQFFLGTTNK RAKTVVLHID GLDDTSRRNL CEEALLKIKG VISFTFQMAV 190 200 210 220 230 240 QRCVVRIRSD LKAEALASAI ASTKVMKAQQ VVKSESGEEM LVPFQDTPVE VEQNTELPDY 250 260 270 280 LPEDESPTKE QDKAVSRVGS HPEGGASWLS TAANFLSRSF YW

References

[1]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Placenta.
[3]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed: 17974005] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 78-282. Tissue: Lymph node.
[4]	Colinge J., Superti-Furga G., Bennett K.L. Submitted (OCT-2008) to UniProtKB Cited for: IDENTIFICATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.
[5]	"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions." Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K. Sci. Signal. 2:RA46-RA46(2009) [PubMed: 19690332] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-260, MASS SPECTROMETRY. Tissue: T-cell.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AK001373 mRNA. Translation: BAA91656.1. AK024053 mRNA. Translation: BAB14803.1. BC011607 mRNA. Translation: AAH11607.1. AL512767 mRNA. Translation: CAC21684.1.
IPI	IPI00018260.
RefSeq	NP_060590.1.
UniGene	Hs.269542
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q9NVT9.
PTM databases
PhosphoSite	Q9NVT9.
Proteomic databases
PeptideAtlas	Q9NVT9.
PRIDE	Q9NVT9.
Genome annotation databases
Ensembl	ENST00000276569; ENSP00000276569; ENSG00000104442; Homo sapiens. [Genome view]
GeneID	55156.
KEGG	hsa:55156.
UCSC	uc003xvl.1. human.
Organism-specific databases
CTD	55156.
GeneCards	GC08M066677.
HGNC	HGNC:17684. ARMC1.
HPA	HPA026085.
PharmGKB	PA134882659.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	Q9NVT9.
HOVERGEN	Q9NVT9.
OMA	ESPSKEQ
OrthoDB	EOG9CVJT8
Gene expression databases
ArrayExpress	Q9NVT9.
Bgee	Q9NVT9.
CleanEx	HS_ARMC1.
Genevestigator	Q9NVT9.
GermOnline	ENSG00000104442. Homo sapiens.
Family and domain databases
InterPro	IPR016024. ARM-type_fold. IPR000225. Armadillo. IPR006121. HeavyMe_transpt. IPR016617. UCP013899_metal_bd. [Graphical view]
Pfam	PF00514. Arm. 1 hit. [Graphical view]
PIRSF	PIRSF013899. UCP013899. 1 hit.
PROSITE	PS50176. ARM_REPEAT. False negative. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	58903.

Entry information

Entry name

ARMC1_HUMAN

Accession

Primary (citable) accession number: Q9NVT9
Secondary accession number(s): Q9H018, Q9H820

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	October 1, 2000
Last modified:	November 24, 2009
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.