Q9NVT9 (ARMC1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Armadillo repeat-containing protein 1

Gene names

Name:	ARMC1
Synonyms:	ARCP

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	282 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 ARM repeat.

Ontologies

Keywords
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	metal ion transport Inferred from electronic annotation. Source: InterPro
Molecular function	metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 282	282	Armadillo repeat-containing protein 1		PRO_0000240882
Regions
	Repeat	39 – 81	43	ARM
Amino acid modifications
	Modified residue	260	1	Phosphoserine Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Q9NVT9 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 9CDF2DCFEC6C3A08	FASTA	282	31,281
	10 20 30 40 50 60 MNSSTSTMSE EPDALSVVNQ LRDLAADPLN RRAIVQDQGC LPGLILFMDH PNPPVVHSAL 70 80 90 100 110 120 LALRYLAECR ANREKMKGEL GMMLSLQNVI QKTTTPGETK LLASEIYDIL QSSNMADGDS 130 140 150 160 170 180 FNEMNSRRRK AQFFLGTTNK RAKTVVLHID GLDDTSRRNL CEEALLKIKG VISFTFQMAV 190 200 210 220 230 240 QRCVVRIRSD LKAEALASAI ASTKVMKAQQ VVKSESGEEM LVPFQDTPVE VEQNTELPDY 250 260 270 280 LPEDESPTKE QDKAVSRVGS HPEGGASWLS TAANFLSRSF YW

References

[1]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Placenta.
[3]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed: 17974005] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 78-282. Tissue: Lymph node.
[4]	"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions." Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K. Sci. Signal. 2:RA46-RA46(2009) [PubMed: 19690332] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-260, MASS SPECTROMETRY. Tissue: Leukemic T-cell.
[5]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed: 21269460] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK001373 mRNA. Translation: BAA91656.1. AK024053 mRNA. Translation: BAB14803.1. BC011607 mRNA. Translation: AAH11607.1. AL512767 mRNA. Translation: CAC21684.1.
IPI	IPI00018260.
RefSeq	NP_060590.1. NM_018120.4.
UniGene	Hs.269542.
3D structure databases
ProteinModelPortal	Q9NVT9.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9NVT9. 2 interactions.
STRING	Q9NVT9.
PTM databases
PhosphoSite	Q9NVT9.
Polymorphism databases
DMDM	74734555.
Proteomic databases
PeptideAtlas	Q9NVT9.
PRIDE	Q9NVT9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000276569; ENSP00000276569; ENSG00000104442.
GeneID	55156.
KEGG	hsa:55156.
UCSC	uc003xvl.1. human.
Organism-specific databases
CTD	55156.
GeneCards	GC08M066515.
H-InvDB	HIX0007549.
HGNC	HGNC:17684. ARMC1.
HPA	HPA026085.
neXtProt	NX_Q9NVT9.
PharmGKB	PA134882659.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG15492.
GeneTree	ENSGT00390000014100.
HOGENOM	HBG713829.
HOVERGEN	HBG055281.
InParanoid	Q9NVT9.
OMA	EVEQNTD.
OrthoDB	EOG48KRBS.
PhylomeDB	Q9NVT9.
Gene expression databases
ArrayExpress	Q9NVT9.
Bgee	Q9NVT9.
CleanEx	HS_ARMC1.
Genevestigator	Q9NVT9.
GermOnline	ENSG00000104442. Homo sapiens.
Family and domain databases
InterPro	IPR011989. ARM-like. IPR016024. ARM-type_fold. IPR000225. Armadillo. IPR006121. HeavyMe-assoc_HMA. IPR016617. UCP013899_metal-bd. [Graphical view]
Gene3D	G3DSA:1.25.10.10. ARM-like. 1 hit.
Pfam	PF00514. Arm. 1 hit. [Graphical view]
PIRSF	PIRSF013899. UCP013899. 1 hit.
SUPFAM	SSF48371. ARM-type_fold. 1 hit. SSF55008. HeavyMe_transpt. 1 hit.
PROSITE	PS50176. ARM_REPEAT. False negative. [Graphical view]
ProtoNet	Search...
Other
NextBio	58903.

Entry information

Entry name

ARMC1_HUMAN

Accession

Primary (citable) accession number: Q9NVT9
Secondary accession number(s): Q9H018, Q9H820

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	October 1, 2000
Last modified:	January 25, 2012
This is version 77 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.