Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9NVM9

- ASUN_HUMAN

UniProt

Q9NVM9 - ASUN_HUMAN

Protein

Protein asunder homolog

Gene

ASUN

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 2 (19 Jul 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis.2 Publications

    GO - Molecular functioni

    1. protein binding Source: IntAct

    GO - Biological processi

    1. mitotic nuclear division Source: UniProtKB-KW
    2. regulation of fertilization Source: UniProtKB
    3. regulation of mitotic cell cycle Source: UniProtKB
    4. sperm motility Source: UniProtKB

    Keywords - Biological processi

    Cell cycle, Cell division, Mitosis

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein asunder homolog
    Alternative name(s):
    Cell cycle regulator Mat89Bb homolog
    Germ cell tumor 1
    Sarcoma antigen NY-SAR-95
    Gene namesi
    Name:ASUN
    Synonyms:C12orf11, GCT1
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 12

    Organism-specific databases

    HGNCiHGNC:20174. ASUN.

    Subcellular locationi

    Cytoplasm 1 Publication

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB
    2. nucleus Source: UniProtKB

    Keywords - Cellular componenti

    Cytoplasm

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134892469.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 706706Protein asunder homologPRO_0000089845Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei626 – 6261Phosphoserine3 Publications

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiQ9NVM9.
    PaxDbiQ9NVM9.
    PeptideAtlasiQ9NVM9.
    PRIDEiQ9NVM9.

    PTM databases

    PhosphoSiteiQ9NVM9.

    Expressioni

    Tissue specificityi

    Widely expressed. Tends to be up-regulated in seminomas compared to normal testis.1 Publication

    Gene expression databases

    ArrayExpressiQ9NVM9.
    BgeeiQ9NVM9.
    CleanExiHS_C12orf11.
    GenevestigatoriQ9NVM9.

    Organism-specific databases

    HPAiHPA039543.

    Interactioni

    Subunit structurei

    Interacts with PAFAH1B1; this interaction may be required for proper recruitment of dynein complexes to the nuclear envelope at prophase.1 Publication

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    CBFBQ139512EBI-741429,EBI-718750

    Protein-protein interaction databases

    BioGridi120846. 14 interactions.
    IntActiQ9NVM9. 4 interactions.
    MINTiMINT-6782559.
    STRINGi9606.ENSP00000261191.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9NVM9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili567 – 62256Sequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Belongs to the asunder family.Curated

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiNOG301038.
    HOGENOMiHOG000046389.
    InParanoidiQ9NVM9.
    OMAiNSVELHY.
    OrthoDBiEOG7TF78D.
    PhylomeDBiQ9NVM9.
    TreeFamiTF105815.

    Family and domain databases

    InterProiIPR019355. Cell_cycle_regulator_Mat89Bb.
    [Graphical view]
    PfamiPF10221. DUF2151. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q9NVM9-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MKIFSESHKT VFVVDHCPYM AESCRQHVEF DMLVKNRTQG IIPLAPISKS    50
    LWTCSVESSM EYCRIMYDIF PFKKLVNFIV SDSGAHVLNS WTQEDQNLQE 100
    LMAALAAVGP PNPRADPECC SILHGLVAAV ETLCKITEYQ HEARTLLMEN 150
    AERVGNRGRI ICITNAKSDS HVRMLEDCVQ ETIHEHNKLA ANSDHLMQIQ 200
    KCELVLIHTY PVGEDSLVSD RSKKELSPVL TSEVHSVRAG RHLATKLNIL 250
    VQQHFDLAST TITNIPMKEE QHANTSANYD VELLHHKDAH VDFLKSGDSH 300
    LGGGSREGSF KETITLKWCT PRTNNIELHY CTGAYRISPV DVNSRPSSCL 350
    TNFLLNGRSV LLEQPRKSGS KVISHMLSSH GGEIFLHVLS SSRSILEDPP 400
    SISEGCGGRV TDYRITDFGE FMRENRLTPF LDPRYKIDGS LEVPLERAKD 450
    QLEKHTRYWP MIISQTTIFN MQAVVPLASV IVKESLTEED VLNCQKTIYN 500
    LVDMERKNDP LPISTVGTRG KGPKRDEQYR IMWNELETLV RAHINNSEKH 550
    QRVLECLMAC RSKPPEEEER KKRGRKREDK EDKSEKAVKD YEQEKSWQDS 600
    ERLKGILERG KEELAEAEII KDSPDSPEPP NKKPLVEMDE TPQVEKSKGP 650
    VSLLSLWSNR INTANSRKHQ EFAGRLNSVN NRAELYQHLK EENGMETTEN 700
    GKASRQ 706
    Length:706
    Mass (Da):80,225
    Last modified:July 19, 2005 - v2
    Checksum:i925C733184461EA6
    GO
    Isoform 2 (identifier: Q9NVM9-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-101: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:605
    Mass (Da):68,494
    Checksum:i7D9017DE546CF1BD
    GO

    Sequence cautioni

    The sequence AAO65180.1 differs from that shown. Reason: Frameshift at positions 414, 445, 483, 498 and 507.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti29 – 291E → G in BAA91725. (PubMed:14702039)Curated
    Sequence conflicti53 – 531T → P in BAA91725. (PubMed:14702039)Curated
    Sequence conflicti75 – 751L → P in BAA91725. (PubMed:14702039)Curated
    Sequence conflicti454 – 4541K → R in BAA91721. (PubMed:14702039)Curated
    Sequence conflicti457 – 4571R → P in BAA91721. (PubMed:14702039)Curated
    Sequence conflicti459 – 4591W → R in BAA91725. (PubMed:14702039)Curated
    Sequence conflicti484 – 4841E → K in AAO65180. (PubMed:12601173)Curated
    Sequence conflicti490 – 4901D → N in AAO65180. (PubMed:12601173)Curated
    Sequence conflicti699 – 6991E → K in AAH03081. (PubMed:15489334)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti66 – 661M → T.
    Corresponds to variant rs2306852 [ dbSNP | Ensembl ].
    VAR_050864
    Natural varianti227 – 2271S → P in a colorectal cancer sample; somatic mutation. 1 Publication
    VAR_035673

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 101101Missing in isoform 2. 1 PublicationVSP_056514Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK001492 mRNA. Translation: BAA91721.1.
    AK001499 mRNA. Translation: BAA91725.1.
    AK297948 mRNA. Translation: BAG60263.1.
    AC024093 Genomic DNA. No translation available.
    BC003081 mRNA. Translation: AAH03081.1.
    BC008368 mRNA. Translation: AAH08368.1.
    AY211927 mRNA. Translation: AAO65180.1. Frameshift.
    AL137401 mRNA. Translation: CAB70726.1.
    CCDSiCCDS8708.1.
    PIRiT46457.
    RefSeqiNP_060634.2. NM_018164.2.
    XP_006719169.1. XM_006719106.1.
    UniGeneiHs.505077.

    Genome annotation databases

    EnsembliENST00000261191; ENSP00000261191; ENSG00000064102.
    ENST00000539625; ENSP00000443724; ENSG00000064102.
    GeneIDi55726.
    KEGGihsa:55726.
    UCSCiuc001rhk.4. human.

    Polymorphism databases

    DMDMi71153010.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK001492 mRNA. Translation: BAA91721.1 .
    AK001499 mRNA. Translation: BAA91725.1 .
    AK297948 mRNA. Translation: BAG60263.1 .
    AC024093 Genomic DNA. No translation available.
    BC003081 mRNA. Translation: AAH03081.1 .
    BC008368 mRNA. Translation: AAH08368.1 .
    AY211927 mRNA. Translation: AAO65180.1 . Frameshift.
    AL137401 mRNA. Translation: CAB70726.1 .
    CCDSi CCDS8708.1.
    PIRi T46457.
    RefSeqi NP_060634.2. NM_018164.2.
    XP_006719169.1. XM_006719106.1.
    UniGenei Hs.505077.

    3D structure databases

    ProteinModelPortali Q9NVM9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 120846. 14 interactions.
    IntActi Q9NVM9. 4 interactions.
    MINTi MINT-6782559.
    STRINGi 9606.ENSP00000261191.

    PTM databases

    PhosphoSitei Q9NVM9.

    Polymorphism databases

    DMDMi 71153010.

    Proteomic databases

    MaxQBi Q9NVM9.
    PaxDbi Q9NVM9.
    PeptideAtlasi Q9NVM9.
    PRIDEi Q9NVM9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000261191 ; ENSP00000261191 ; ENSG00000064102 .
    ENST00000539625 ; ENSP00000443724 ; ENSG00000064102 .
    GeneIDi 55726.
    KEGGi hsa:55726.
    UCSCi uc001rhk.4. human.

    Organism-specific databases

    CTDi 55726.
    GeneCardsi GC12M027059.
    H-InvDB HIX0010501.
    HGNCi HGNC:20174. ASUN.
    HPAi HPA039543.
    MIMi 615079. gene.
    neXtProti NX_Q9NVM9.
    PharmGKBi PA134892469.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG301038.
    HOGENOMi HOG000046389.
    InParanoidi Q9NVM9.
    OMAi NSVELHY.
    OrthoDBi EOG7TF78D.
    PhylomeDBi Q9NVM9.
    TreeFami TF105815.

    Miscellaneous databases

    GeneWikii C12orf11.
    GenomeRNAii 55726.
    NextBioi 60635.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9NVM9.
    Bgeei Q9NVM9.
    CleanExi HS_C12orf11.
    Genevestigatori Q9NVM9.

    Family and domain databases

    InterProi IPR019355. Cell_cycle_regulator_Mat89Bb.
    [Graphical view ]
    Pfami PF10221. DUF2151. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    2. "The finished DNA sequence of human chromosome 12."
      Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
      , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A.
      Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Eye and Lymph.
    4. Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 269-513 (ISOFORM 1).
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 568-706 (ISOFORM 1).
      Tissue: Testis.
    6. "Genomic and expression analysis of the 12p11-p12 amplicon using EST arrays identifies two novel amplified and overexpressed genes."
      Bourdon V., Naef F., Rao P.H., Reuter V., Mok S.C., Bosl G.J., Koul S., Murty V.V., Kucherlapati R.S., Chaganti R.S.
      Cancer Res. 62:6218-6223(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: TISSUE SPECIFICITY.
    7. "Drosophila genome-scale screen for PAN GU kinase substrates identifies Mat89Bb as a cell cycle regulator."
      Lee L.A., Lee E., Anderson M.A., Vardy L., Tahinci E., Ali S.M., Kashevsky H., Benasutti M., Kirschner M.W., Orr-Weaver T.L.
      Dev. Cell 8:435-442(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    8. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
      Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-626, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    9. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-626, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    10. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-626, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    11. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    12. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    13. "Human Asunder promotes dynein recruitment and centrosomal tethering to the nucleus at mitotic entry."
      Jodoin J.N., Shboul M., Sitaram P., Zein-Sabatto H., Reversade B., Lee E., Lee L.A.
      Mol. Biol. Cell 23:4713-4724(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, INTERACTION WITH PAFAH1B1, SUBCELLULAR LOCATION.
    14. Cited for: VARIANT [LARGE SCALE ANALYSIS] PRO-227.

    Entry informationi

    Entry nameiASUN_HUMAN
    AccessioniPrimary (citable) accession number: Q9NVM9
    Secondary accession number(s): B4DNK1
    , Q86WE2, Q96HM2, Q9BTX2, Q9NTB6, Q9NVM5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 19, 2005
    Last sequence update: July 19, 2005
    Last modified: October 1, 2014
    This is version 88 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Miscellaneous

    RNAi in HeLa cells results in a multinucleated phenotype.

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 12
      Human chromosome 12: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3