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Q9NVH2

- INT7_HUMAN

UniProt

Q9NVH2 - INT7_HUMAN

Protein

Integrator complex subunit 7

Gene

INTS7

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 106 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
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    Functioni

    Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Plays a role in DNA damage response (DDR) signaling during the S phase.1 Publication

    GO - Molecular functioni

    1. protein binding Source: UniProtKB

    GO - Biological processi

    1. cellular response to ionizing radiation Source: UniProtKB
    2. DNA damage checkpoint Source: UniProtKB
    3. snRNA processing Source: HGNC

    Keywords - Biological processi

    DNA damage

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Integrator complex subunit 7
    Short name:
    Int7
    Gene namesi
    Name:INTS7
    Synonyms:C1orf73
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 1

    Organism-specific databases

    HGNCiHGNC:24484. INTS7.

    Subcellular locationi

    Nucleus 1 Publication. Chromosome 1 Publication
    Note: Localizes to sites of DNA damage in a H2AX-independent manner.

    GO - Cellular componenti

    1. chromosome Source: UniProtKB
    2. integrator complex Source: HGNC

    Keywords - Cellular componenti

    Chromosome, Nucleus

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA142672522.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 962962Integrator complex subunit 7PRO_0000259549Add
    BLAST

    Proteomic databases

    MaxQBiQ9NVH2.
    PaxDbiQ9NVH2.
    PRIDEiQ9NVH2.

    PTM databases

    PhosphoSiteiQ9NVH2.

    Expressioni

    Gene expression databases

    BgeeiQ9NVH2.
    CleanExiHS_INTS7.
    GenevestigatoriQ9NVH2.

    Interactioni

    Subunit structurei

    Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, CPSF3L/INTS11 and INTS12. Interacts with NABP2.2 Publications

    Protein-protein interaction databases

    BioGridi117404. 15 interactions.
    MINTiMINT-4540227.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9NVH2.
    SMRiQ9NVH2. Positions 412-438.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi937 – 95519Gln-richAdd
    BLAST

    Sequence similaritiesi

    Belongs to the Integrator subunit 7 family.Curated

    Phylogenomic databases

    eggNOGiNOG286030.
    HOGENOMiHOG000063719.
    HOVERGENiHBG079489.
    InParanoidiQ9NVH2.
    KOiK13144.
    OMAiHMHHDAS.
    OrthoDBiEOG78SQKT.
    PhylomeDBiQ9NVH2.
    TreeFamiTF106105.

    Family and domain databases

    Gene3Di1.25.10.10. 2 hits.
    InterProiIPR011989. ARM-like.
    IPR016024. ARM-type_fold.
    [Graphical view]
    SUPFAMiSSF48371. SSF48371. 1 hit.

    Sequences (4)i

    Sequence statusi: Complete.

    This entry describes 4 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q9NVH2-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MASNSTKSFL ADAGYGEQEL DANSALMELD KGLRSGKLGE QCEAVVRFPR    50
    LFQKYPFPIL INSAFLKLAD VFRVGNNFLR LCVLKVTQQS EKHLEKILNV 100
    DEFVKRIFSV IHSNDPVARA ITLRMLGSLA SIIPERKNAH HSIRQSLDSH 150
    DNVEVEAAVF AAANFSAQSK DFAVGICNKI SEMIQGLATP VDLKLKLIPI 200
    LQHMHHDAIL ASSARQLLQQ LVTSYPSTKM VIVSLHTFTL LAASSLVDTP 250
    KQIQLLLQYL KNDPRKAVKR LAIQDLKLLA NKTPHTWSRE NIQALCECAL 300
    QTPYDSLKLG MLSVLSTLSG TIAIKHYFSI VPGNVSSSPR SSDLVKLAQE 350
    CCYHNNRGIA AHGVRVLTNI TVSCQEKDLL ALEQDAVFGL ESLLVLCSQD 400
    DSPGAQATLK IALNCMVKLA KGRPHLSQSV VETLLTQLHS AQDAARILMC 450
    HCLAAIAMQL PVLGDGMLGD LMELYKVIGR SATDKQQELL VSLATVIFVA 500
    SQKALSVESK AVIKQQLESV SNGWTVYRIA RQASRMGNHD MAKELYQSLL 550
    TQVASEHFYF WLNSLKEFSH AEQCLTGLQE ENYSSALSCI AESLKFYHKG 600
    IASLTAASTP LNPLSFQCEF VKLRIDLLQA FSQLICTCNS LKTSPPPAIA 650
    TTIAMTLGND LQRCGRISNQ MKQSMEEFRS LASRYGDLYQ ASFDADSATL 700
    RNVELQQQSC LLISHAIEAL ILDPESASFQ EYGSTGTAHA DSEYERRMMS 750
    VYNHVLEEVE SLNRKYTPVS YMHTACLCNA IIALLKVPLS FQRYFFQKLQ 800
    STSIKLALSP SPRNPAEPIA VQNNQQLALK VEGVVQHGSK PGLFRKIQSV 850
    CLNVSSTLQS KSGQDYKIPI DNMTNEMEQR VEPHNDYFST QFLLNFAILG 900
    THNITVESSV KDANGIVWKT GPRTTIFVKS LEDPYSQQIR LQQQQAQQPL 950
    QQQQQRNAYT RF 962
    Length:962
    Mass (Da):106,834
    Last modified:October 1, 2000 - v1
    Checksum:i45253FE31FD5B96D
    GO
    Isoform 2 (identifier: Q9NVH2-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         759-772: Missing.

    Show »
    Length:948
    Mass (Da):105,165
    Checksum:i1458903417E4B25C
    GO
    Isoform 3 (identifier: Q9NVH2-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         773-792: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:942
    Mass (Da):104,696
    Checksum:i785F91471229C53E
    GO
    Isoform 4 (identifier: Q9NVH2-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         76-124: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:913
    Mass (Da):101,118
    Checksum:i419D8CE78A8CAA74
    GO

    Sequence cautioni

    The sequence BAB14116.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
    The sequence BAA91650.1 differs from that shown. Reason: Erroneous termination at position 618. Translated as Cys.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti805 – 8051K → T in BAB14116. (PubMed:14702039)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti425 – 4251H → R.2 Publications
    Corresponds to variant rs17851788 [ dbSNP | Ensembl ].
    VAR_028963

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei76 – 12449Missing in isoform 4. 1 PublicationVSP_043201Add
    BLAST
    Alternative sequencei759 – 77214Missing in isoform 2. 2 PublicationsVSP_021463Add
    BLAST
    Alternative sequencei773 – 79220Missing in isoform 3. 1 PublicationVSP_021464Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK001363 mRNA. Translation: BAA91650.1. Sequence problems.
    AK001598 mRNA. Translation: BAA91779.1.
    AK022509 mRNA. Translation: BAB14067.1.
    AK022589 mRNA. Translation: BAB14116.1. Different initiation.
    AK297225 mRNA. Translation: BAG59708.1.
    AL117576 mRNA. Translation: CAB56000.1.
    AM392654 mRNA. Translation: CAL37532.1.
    AC092814 Genomic DNA. No translation available.
    CH471100 Genomic DNA. Translation: EAW93406.1.
    BC020523 mRNA. Translation: AAH20523.1.
    BC030716 mRNA. Translation: AAH30716.1.
    BC033918 mRNA. Translation: AAH33918.1.
    AL133049 mRNA. Translation: CAB61376.1.
    BK005725 mRNA. Translation: DAA05725.1.
    CCDSiCCDS1501.1. [Q9NVH2-1]
    CCDS55683.1. [Q9NVH2-4]
    CCDS55684.1. [Q9NVH2-3]
    CCDS55685.1. [Q9NVH2-2]
    PIRiT17310.
    T42652.
    RefSeqiNP_001186738.1. NM_001199809.1. [Q9NVH2-4]
    NP_001186740.1. NM_001199811.1. [Q9NVH2-2]
    NP_001186741.1. NM_001199812.1. [Q9NVH2-3]
    NP_056249.1. NM_015434.3. [Q9NVH2-1]
    UniGeneiHs.369285.

    Genome annotation databases

    EnsembliENST00000366992; ENSP00000355959; ENSG00000143493. [Q9NVH2-3]
    ENST00000366993; ENSP00000355960; ENSG00000143493. [Q9NVH2-2]
    ENST00000366994; ENSP00000355961; ENSG00000143493. [Q9NVH2-1]
    ENST00000440600; ENSP00000388908; ENSG00000143493. [Q9NVH2-4]
    GeneIDi25896.
    KEGGihsa:25896.
    UCSCiuc001hiw.2. human. [Q9NVH2-1]
    uc001hiy.2. human. [Q9NVH2-2]
    uc009xdb.2. human. [Q9NVH2-3]
    uc010pta.2. human. [Q9NVH2-4]

    Polymorphism databases

    DMDMi74752993.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK001363 mRNA. Translation: BAA91650.1 . Sequence problems.
    AK001598 mRNA. Translation: BAA91779.1 .
    AK022509 mRNA. Translation: BAB14067.1 .
    AK022589 mRNA. Translation: BAB14116.1 . Different initiation.
    AK297225 mRNA. Translation: BAG59708.1 .
    AL117576 mRNA. Translation: CAB56000.1 .
    AM392654 mRNA. Translation: CAL37532.1 .
    AC092814 Genomic DNA. No translation available.
    CH471100 Genomic DNA. Translation: EAW93406.1 .
    BC020523 mRNA. Translation: AAH20523.1 .
    BC030716 mRNA. Translation: AAH30716.1 .
    BC033918 mRNA. Translation: AAH33918.1 .
    AL133049 mRNA. Translation: CAB61376.1 .
    BK005725 mRNA. Translation: DAA05725.1 .
    CCDSi CCDS1501.1. [Q9NVH2-1 ]
    CCDS55683.1. [Q9NVH2-4 ]
    CCDS55684.1. [Q9NVH2-3 ]
    CCDS55685.1. [Q9NVH2-2 ]
    PIRi T17310.
    T42652.
    RefSeqi NP_001186738.1. NM_001199809.1. [Q9NVH2-4 ]
    NP_001186740.1. NM_001199811.1. [Q9NVH2-2 ]
    NP_001186741.1. NM_001199812.1. [Q9NVH2-3 ]
    NP_056249.1. NM_015434.3. [Q9NVH2-1 ]
    UniGenei Hs.369285.

    3D structure databases

    ProteinModelPortali Q9NVH2.
    SMRi Q9NVH2. Positions 412-438.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 117404. 15 interactions.
    MINTi MINT-4540227.

    PTM databases

    PhosphoSitei Q9NVH2.

    Polymorphism databases

    DMDMi 74752993.

    Proteomic databases

    MaxQBi Q9NVH2.
    PaxDbi Q9NVH2.
    PRIDEi Q9NVH2.

    Protocols and materials databases

    DNASUi 25896.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000366992 ; ENSP00000355959 ; ENSG00000143493 . [Q9NVH2-3 ]
    ENST00000366993 ; ENSP00000355960 ; ENSG00000143493 . [Q9NVH2-2 ]
    ENST00000366994 ; ENSP00000355961 ; ENSG00000143493 . [Q9NVH2-1 ]
    ENST00000440600 ; ENSP00000388908 ; ENSG00000143493 . [Q9NVH2-4 ]
    GeneIDi 25896.
    KEGGi hsa:25896.
    UCSCi uc001hiw.2. human. [Q9NVH2-1 ]
    uc001hiy.2. human. [Q9NVH2-2 ]
    uc009xdb.2. human. [Q9NVH2-3 ]
    uc010pta.2. human. [Q9NVH2-4 ]

    Organism-specific databases

    CTDi 25896.
    GeneCardsi GC01M212113.
    HGNCi HGNC:24484. INTS7.
    MIMi 611350. gene.
    neXtProti NX_Q9NVH2.
    PharmGKBi PA142672522.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG286030.
    HOGENOMi HOG000063719.
    HOVERGENi HBG079489.
    InParanoidi Q9NVH2.
    KOi K13144.
    OMAi HMHHDAS.
    OrthoDBi EOG78SQKT.
    PhylomeDBi Q9NVH2.
    TreeFami TF106105.

    Miscellaneous databases

    ChiTaRSi INTS7. human.
    GeneWikii INTS7.
    GenomeRNAii 25896.
    NextBioi 47341.
    PROi Q9NVH2.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q9NVH2.
    CleanExi HS_INTS7.
    Genevestigatori Q9NVH2.

    Family and domain databases

    Gene3Di 1.25.10.10. 2 hits.
    InterProi IPR011989. ARM-like.
    IPR016024. ARM-type_fold.
    [Graphical view ]
    SUPFAMi SSF48371. SSF48371. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 3 AND 4).
      Tissue: Brain.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANT ARG-425.
      Tissue: Testis.
    3. "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
      , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
      Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANT ARG-425.
      Tissue: Skin and Uterus.
    6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 204-962 (ISOFORM 1).
      Tissue: Testis.
    7. "Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II."
      Baillat D., Hakimi M.-A., Naeaer A.M., Shilatifard A., Cooch N., Shiekhattar R.
      Cell 123:265-276(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY, IDENTIFICATION IN THE INTEGRATOR COMPLEX.
    8. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M.
      Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    10. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    11. "A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling."
      Cotta-Ramusino C., McDonald E.R. III, Hurov K., Sowa M.E., Harper J.W., Elledge S.J.
      Science 332:1313-1317(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, INTERACTION WITH NABP2, SUBCELLULAR LOCATION.

    Entry informationi

    Entry nameiINT7_HUMAN
    AccessioniPrimary (citable) accession number: Q9NVH2
    Secondary accession number(s): B4DLZ6
    , B7WNP6, B7WPB6, Q8N4K7, Q8WUH5, Q9H9V3, Q9NVU5, Q9UFC6, Q9UFM3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 31, 2006
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 106 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 1
      Human chromosome 1: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3