Q9NUU6 (F105A_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein FAM105A

Gene names

Name:

FAM105A

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	356 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the FAM105 family.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 356	356	Protein FAM105A		PRO_0000274404
Natural variations
	Natural variant	319	1	F → L. Corresponds to variant rs16903574 [ dbSNP | Ensembl ].		VAR_030281
Experimental info
	Sequence conflict	322	1	N → I in BAD96451. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q9NUU6 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 91EEC6C877D5315B	FASTA	356	42,196
	10 20 30 40 50 60 MAATRSPTRA RERERSGAPA AGSDQVHSWM LATSQALDTV WRMAKGFVML AVSFLVAAIC 70 80 90 100 110 120 YFRRLHLYSG HKLKWWIGYL QRKFKRNLSV EAEVDLLSYC AREWKGETPR NKLMRKAYEE 130 140 150 160 170 180 LFWRHHIKCV RQVRRDNYDA LRSVLFQIFS QGISFPSWMK EKDIVKLPEK LLFSQGCNWI 190 200 210 220 230 240 QQYSFGPEKY TGSNVFGKLR KYVELLKTQW TEFNGIRDYH KRGSMCNTLF SDAILEYKLY 250 260 270 280 290 300 EALKFIMLYQ VTEVYEQMKT KKVIPSLFRL LFSRETSSDP LSFMMNHLNS VGDTCGLEQI 310 320 330 340 350 DMFILGYSLE VKIKVFRLFK FNSRDFEVCY PEEPLRDWPE ISLLTENDRH YHIPVF

References

[1]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Placenta.
[2]	Suzuki Y., Sugano S., Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S. Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Colon.
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Eye.
[4]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed: 17974005] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 239-356. Tissue: Lymph node.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK001989 mRNA. Translation: BAA92023.1. AK222731 mRNA. Translation: BAD96451.1. BC011524 mRNA. Translation: AAH11524.1. AL512750 mRNA. Translation: CAC21673.1.
IPI	IPI00004563.
RefSeq	NP_061891.1. NM_019018.2.
UniGene	Hs.155085.
3D structure databases
ProteinModelPortal	Q9NUU6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9NUU6.
PTM databases
PhosphoSite	Q9NUU6.
Polymorphism databases
DMDM	74734394.
Proteomic databases
PRIDE	Q9NUU6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000274217; ENSP00000274217; ENSG00000145569.
GeneID	54491.
KEGG	hsa:54491.
UCSC	uc003jfj.1. human.
Organism-specific databases
CTD	54491.
GeneCards	GC05P014581.
HGNC	HGNC:25629. FAM105A.
neXtProt	NX_Q9NUU6.
PharmGKB	PA142671788.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG09873.
GeneTree	ENSGT00390000009802.
HOGENOM	HBG445927.
HOVERGEN	HBG059856.
InParanoid	Q9NUU6.
OMA	HLNSVGD.
OrthoDB	EOG4894MP.
PhylomeDB	Q9NUU6.
Gene expression databases
ArrayExpress	Q9NUU6.
Bgee	Q9NUU6.
CleanEx	HS_FAM105A.
Genevestigator	Q9NUU6.
Family and domain databases
InterPro	IPR023235. FAM105. IPR023236. FAM105A. [Graphical view]
PRINTS	PR02055. PROTEINF105. PR02056. PROTEINF105A.
ProtoNet	Search...
Other
NextBio	56815.

Entry information

Entry name

F105A_HUMAN

Accession

Primary (citable) accession number: Q9NUU6
Secondary accession number(s): Q53H50, Q9H037

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 6, 2007
Last sequence update:	October 1, 2000
Last modified:	December 14, 2011
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.