Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

T-complex protein 11-like protein 1

Gene

TCP11L1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
T-complex protein 11-like protein 1
Gene namesi
Name:TCP11L1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:25655. TCP11L1.

Subcellular locationi

GO - Cellular componenti

  • microtubule Source: UniProtKB

Pathology & Biotechi

Organism-specific databases

DisGeNETi55346.
OpenTargetsiENSG00000176148.
PharmGKBiPA142670824.

Polymorphism and mutation databases

BioMutaiTCP11L1.
DMDMi74734348.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003137471 – 509T-complex protein 11-like protein 1Add BLAST509

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei56PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9NUJ3.
MaxQBiQ9NUJ3.
PaxDbiQ9NUJ3.
PeptideAtlasiQ9NUJ3.
PRIDEiQ9NUJ3.

PTM databases

iPTMnetiQ9NUJ3.
PhosphoSitePlusiQ9NUJ3.

Expressioni

Gene expression databases

BgeeiENSG00000176148.
CleanExiHS_TCP11L1.
ExpressionAtlasiQ9NUJ3. baseline and differential.
GenevisibleiQ9NUJ3. HS.

Organism-specific databases

HPAiHPA005769.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
TBX6O959474EBI-2555179,EBI-2824328

Protein-protein interaction databases

BioGridi120627. 15 interactors.
IntActiQ9NUJ3. 31 interactors.
STRINGi9606.ENSP00000335595.

Structurei

3D structure databases

ProteinModelPortaliQ9NUJ3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TCP11 family.Curated

Phylogenomic databases

eggNOGiKOG1981. Eukaryota.
ENOG410ZDEH. LUCA.
GeneTreeiENSGT00390000008958.
HOGENOMiHOG000231350.
HOVERGENiHBG008348.
InParanoidiQ9NUJ3.
OrthoDBiEOG091G07AC.
PhylomeDBiQ9NUJ3.
TreeFamiTF313385.

Family and domain databases

InterProiView protein in InterPro
IPR008862. Tcp11.
PANTHERiPTHR12832. PTHR12832. 1 hit.
PfamiView protein in Pfam
PF05794. Tcp11. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9NUJ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSENLDKSNV NEAGKSKSND SEEGLEDAVE GADEALQKAI KSDSSSPQRV
60 70 80 90 100
QRPHSSPPRF VTVEELLETA RGVTNMALAH EIVVNGDFQI KPVELPENSL
110 120 130 140 150
KKRVKEIVHK AFWDCLSVQL SEDPPAYDHA IKLVGEIKET LLSFLLPGHT
160 170 180 190 200
RLRNQITEVL DLDLIKQEAE NGALDISKLA EFIIGMMGTL CAPARDEEVK
210 220 230 240 250
KLKDIKEIVP LFREIFSVLD LMKVDMANFA ISSIRPHLMQ QSVEYERKKF
260 270 280 290 300
QEILERQPNS LDFVTQWLEE ASEDLMTQKY KHALPVGGMA AGSGDMPRLS
310 320 330 340 350
PVAVQNYAYL KLLKWDHLQR PFPETVLMDQ SRFHELQLQL EQLTILGAVL
360 370 380 390 400
LVTFSMAAPG ISSQADFAEK LKMIVKILLT DMHLPSFHLK DVLTTIGEKV
410 420 430 440 450
CLEVSSCLSL CGSSPFTTDK ETVLKGQIQA VASPDDPIRR IMESRILTFL
460 470 480 490 500
ETYLASGHQK PLPTVPGGLS PVQRELEEVA IKFARLVNYN KMVFCPYYDA

ILSKILVRS
Length:509
Mass (Da):57,035
Last modified:October 1, 2000 - v1
Checksum:i101F53A05F1B3C30
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_037726109H → Q. Corresponds to variant dbSNP:rs16923785Ensembl.1
Natural variantiVAR_037727178K → R1 PublicationCorresponds to variant dbSNP:rs2273549Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002198 mRNA. Translation: BAA92131.1.
AL121926 Genomic DNA. Translation: CAC48254.1.
CH471064 Genomic DNA. Translation: EAW68206.1.
CH471064 Genomic DNA. Translation: EAW68207.1.
CH471064 Genomic DNA. Translation: EAW68208.1.
CH471064 Genomic DNA. Translation: EAW68209.1.
BC041696 mRNA. Translation: AAH41696.1.
CCDSiCCDS7882.1.
RefSeqiNP_001139013.1. NM_001145541.1.
NP_060863.3. NM_018393.3.
XP_011518509.1. XM_011520207.2.
XP_016873479.1. XM_017017990.1.
UniGeneiHs.655341.

Genome annotation databases

EnsembliENST00000334274; ENSP00000335595; ENSG00000176148.
ENST00000432887; ENSP00000395070; ENSG00000176148.
ENST00000531632; ENSP00000433067; ENSG00000176148.
GeneIDi55346.
KEGGihsa:55346.
UCSCiuc001mud.3. human.

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiT11L1_HUMAN
AccessioniPrimary (citable) accession number: Q9NUJ3
Secondary accession number(s): D3DR01, Q8IVX4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 1, 2000
Last modified: August 30, 2017
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families