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Q9NUJ3

- T11L1_HUMAN

UniProt

Q9NUJ3 - T11L1_HUMAN

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Protein
T-complex protein 11-like protein 1
Gene
TCP11L1
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
T-complex protein 11-like protein 1
Gene namesi
Name:TCP11L1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 11

Organism-specific databases

HGNCiHGNC:25655. TCP11L1.

Subcellular locationi

GO - Cellular componenti

  1. microtubule Source: UniProtKB
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142670824.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 509509T-complex protein 11-like protein 1
PRO_0000313747Add
BLAST

Proteomic databases

MaxQBiQ9NUJ3.
PaxDbiQ9NUJ3.
PRIDEiQ9NUJ3.

PTM databases

PhosphoSiteiQ9NUJ3.

Expressioni

Gene expression databases

ArrayExpressiQ9NUJ3.
BgeeiQ9NUJ3.
CleanExiHS_TCP11L1.
GenevestigatoriQ9NUJ3.

Organism-specific databases

HPAiHPA005769.

Interactioni

Protein-protein interaction databases

BioGridi120627. 5 interactions.
IntActiQ9NUJ3. 3 interactions.
STRINGi9606.ENSP00000335595.

Structurei

3D structure databases

ProteinModelPortaliQ9NUJ3.

Family & Domainsi

Sequence similaritiesi

Belongs to the TCP11 family.

Phylogenomic databases

eggNOGiNOG257003.
HOGENOMiHOG000231350.
HOVERGENiHBG008348.
InParanoidiQ9NUJ3.
PhylomeDBiQ9NUJ3.
TreeFamiTF313385.

Family and domain databases

InterProiIPR008862. Tcp11.
[Graphical view]
PANTHERiPTHR12832. PTHR12832. 1 hit.
PfamiPF05794. Tcp11. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9NUJ3-1 [UniParc]FASTAAdd to Basket

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MSENLDKSNV NEAGKSKSND SEEGLEDAVE GADEALQKAI KSDSSSPQRV    50
QRPHSSPPRF VTVEELLETA RGVTNMALAH EIVVNGDFQI KPVELPENSL 100
KKRVKEIVHK AFWDCLSVQL SEDPPAYDHA IKLVGEIKET LLSFLLPGHT 150
RLRNQITEVL DLDLIKQEAE NGALDISKLA EFIIGMMGTL CAPARDEEVK 200
KLKDIKEIVP LFREIFSVLD LMKVDMANFA ISSIRPHLMQ QSVEYERKKF 250
QEILERQPNS LDFVTQWLEE ASEDLMTQKY KHALPVGGMA AGSGDMPRLS 300
PVAVQNYAYL KLLKWDHLQR PFPETVLMDQ SRFHELQLQL EQLTILGAVL 350
LVTFSMAAPG ISSQADFAEK LKMIVKILLT DMHLPSFHLK DVLTTIGEKV 400
CLEVSSCLSL CGSSPFTTDK ETVLKGQIQA VASPDDPIRR IMESRILTFL 450
ETYLASGHQK PLPTVPGGLS PVQRELEEVA IKFARLVNYN KMVFCPYYDA 500
ILSKILVRS 509
Length:509
Mass (Da):57,035
Last modified:October 1, 2000 - v1
Checksum:i101F53A05F1B3C30
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti109 – 1091H → Q.
Corresponds to variant rs16923785 [ dbSNP | Ensembl ].
VAR_037726
Natural varianti178 – 1781K → R.1 Publication
Corresponds to variant rs2273549 [ dbSNP | Ensembl ].
VAR_037727

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK002198 mRNA. Translation: BAA92131.1.
AL121926 Genomic DNA. Translation: CAC48254.1.
CH471064 Genomic DNA. Translation: EAW68206.1.
CH471064 Genomic DNA. Translation: EAW68207.1.
CH471064 Genomic DNA. Translation: EAW68208.1.
CH471064 Genomic DNA. Translation: EAW68209.1.
BC041696 mRNA. Translation: AAH41696.1.
CCDSiCCDS7882.1.
RefSeqiNP_001139013.1. NM_001145541.1.
NP_060863.3. NM_018393.3.
XP_006718319.1. XM_006718256.1.
UniGeneiHs.655341.

Genome annotation databases

EnsembliENST00000334274; ENSP00000335595; ENSG00000176148.
ENST00000432887; ENSP00000395070; ENSG00000176148.
ENST00000531632; ENSP00000433067; ENSG00000176148.
GeneIDi55346.
KEGGihsa:55346.
UCSCiuc001mud.3. human.

Polymorphism databases

DMDMi74734348.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK002198 mRNA. Translation: BAA92131.1 .
AL121926 Genomic DNA. Translation: CAC48254.1 .
CH471064 Genomic DNA. Translation: EAW68206.1 .
CH471064 Genomic DNA. Translation: EAW68207.1 .
CH471064 Genomic DNA. Translation: EAW68208.1 .
CH471064 Genomic DNA. Translation: EAW68209.1 .
BC041696 mRNA. Translation: AAH41696.1 .
CCDSi CCDS7882.1.
RefSeqi NP_001139013.1. NM_001145541.1.
NP_060863.3. NM_018393.3.
XP_006718319.1. XM_006718256.1.
UniGenei Hs.655341.

3D structure databases

ProteinModelPortali Q9NUJ3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 120627. 5 interactions.
IntActi Q9NUJ3. 3 interactions.
STRINGi 9606.ENSP00000335595.

PTM databases

PhosphoSitei Q9NUJ3.

Polymorphism databases

DMDMi 74734348.

Proteomic databases

MaxQBi Q9NUJ3.
PaxDbi Q9NUJ3.
PRIDEi Q9NUJ3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000334274 ; ENSP00000335595 ; ENSG00000176148 .
ENST00000432887 ; ENSP00000395070 ; ENSG00000176148 .
ENST00000531632 ; ENSP00000433067 ; ENSG00000176148 .
GeneIDi 55346.
KEGGi hsa:55346.
UCSCi uc001mud.3. human.

Organism-specific databases

CTDi 55346.
GeneCardsi GC11P033018.
H-InvDB HIX0009536.
HGNCi HGNC:25655. TCP11L1.
HPAi HPA005769.
neXtProti NX_Q9NUJ3.
PharmGKBi PA142670824.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG257003.
HOGENOMi HOG000231350.
HOVERGENi HBG008348.
InParanoidi Q9NUJ3.
PhylomeDBi Q9NUJ3.
TreeFami TF313385.

Miscellaneous databases

ChiTaRSi TCP11L1. human.
GenomeRNAii 55346.
NextBioi 59683.
PROi Q9NUJ3.

Gene expression databases

ArrayExpressi Q9NUJ3.
Bgeei Q9NUJ3.
CleanExi HS_TCP11L1.
Genevestigatori Q9NUJ3.

Family and domain databases

InterProi IPR008862. Tcp11.
[Graphical view ]
PANTHERi PTHR12832. PTHR12832. 1 hit.
Pfami PF05794. Tcp11. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Placenta.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ARG-178.
    Tissue: Blood.
  5. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  6. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiT11L1_HUMAN
AccessioniPrimary (citable) accession number: Q9NUJ3
Secondary accession number(s): D3DR01, Q8IVX4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 1, 2000
Last modified: July 9, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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