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Q9NUF9

- Q9NUF9_HUMAN

UniProt

Q9NUF9 - Q9NUF9_HUMAN

Protein

Nucleoside diphosphate kinase

Gene

c371H6.2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    Catalytic activityi

    ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. nucleoside diphosphate kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. CTP biosynthetic process Source: InterPro
    2. GTP biosynthetic process Source: InterPro
    3. UTP biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    KinaseUniRule annotationImported, Transferase

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Nucleoside diphosphate kinaseUniRule annotation (EC:2.7.4.6UniRule annotation)
    Gene namesi
    Name:c371H6.2Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrion Source: Ensembl

    PTM / Processingi

    Proteomic databases

    PRIDEiQ9NUF9.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9NUF9.
    BgeeiQ9NUF9.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9NUF9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the NDK family.

    Phylogenomic databases

    HOVERGENiHBG000423.

    Family and domain databases

    Gene3Di3.30.70.141. 1 hit.
    HAMAPiMF_00451. NDP_kinase.
    InterProiIPR001564. Nucleoside_diP_kinase.
    IPR023005. Nucleoside_diP_kinase_AS.
    [Graphical view]
    PfamiPF00334. NDK. 1 hit.
    [Graphical view]
    PRINTSiPR01243. NUCDPKINASE.
    SMARTiSM00562. NDK. 1 hit.
    [Graphical view]
    SUPFAMiSSF54919. SSF54919. 1 hit.
    PROSITEiPS00469. NDP_KINASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q9NUF9-1 [UniParc]FASTAAdd to Basket

    « Hide

    CTGAHERTFL AVKPDGVQRR LVGEIVRRFE RKGFKLVALK LVQASEELLR    50
    EHYAELRERP FYGRLVKYMA SGPVVAMVWQ GLDVVRTSRA LIGATNPADA 100
    PPGTIRGDFC IEVGKNLIHG SDSVESARRE IALWFRADEL LCWEDSAGHW 150
    LYE 153
    Length:153
    Mass (Da):17,296
    Last modified:October 1, 2000 - v1
    Checksum:i0A2D7059E1CC18EA
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL031718 Genomic DNA. Translation: CAB72319.1.
    UniGeneiHs.514065.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL031718 Genomic DNA. Translation: CAB72319.1 .
    UniGenei Hs.514065.

    3D structure databases

    ProteinModelPortali Q9NUF9.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q9NUF9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG000423.

    Gene expression databases

    ArrayExpressi Q9NUF9.
    Bgeei Q9NUF9.

    Family and domain databases

    Gene3Di 3.30.70.141. 1 hit.
    HAMAPi MF_00451. NDP_kinase.
    InterProi IPR001564. Nucleoside_diP_kinase.
    IPR023005. Nucleoside_diP_kinase_AS.
    [Graphical view ]
    Pfami PF00334. NDK. 1 hit.
    [Graphical view ]
    PRINTSi PR01243. NUCDPKINASE.
    SMARTi SM00562. NDK. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54919. SSF54919. 1 hit.
    PROSITEi PS00469. NDP_KINASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Bagguley C.
      Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ9NUF9_HUMAN
    AccessioniPrimary (citable) accession number: Q9NUF9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2000
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.