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Q9NUC0

- SRTD4_HUMAN

UniProt

Q9NUC0 - SRTD4_HUMAN

Protein

SERTA domain-containing protein 4

Gene

SERTAD4

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 87 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    SERTA domain-containing protein 4
    Gene namesi
    Name:SERTAD4
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 1

    Organism-specific databases

    HGNCiHGNC:25236. SERTAD4.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134897438.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 356356SERTA domain-containing protein 4PRO_0000314139Add
    BLAST

    Proteomic databases

    PaxDbiQ9NUC0.
    PRIDEiQ9NUC0.

    Expressioni

    Gene expression databases

    BgeeiQ9NUC0.
    CleanExiHS_SERTAD4.
    GenevestigatoriQ9NUC0.

    Organism-specific databases

    HPAiHPA027344.
    HPA028514.

    Interactioni

    Protein-protein interaction databases

    BioGridi121121. 4 interactions.
    IntActiQ9NUC0. 3 interactions.
    STRINGi9606.ENSP00000355979.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9NUC0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini101 – 14747SERTAPROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi212 – 24130Ser-richAdd
    BLAST

    Sequence similaritiesi

    Contains 1 SERTA domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG25597.
    HOGENOMiHOG000154425.
    HOVERGENiHBG108514.
    InParanoidiQ9NUC0.
    OMAiIHGEIIM.
    OrthoDBiEOG77Q4X1.
    PhylomeDBiQ9NUC0.
    TreeFamiTF336235.

    Family and domain databases

    InterProiIPR009263. SERTA_dom.
    IPR029708. SERTAD4.
    [Graphical view]
    PANTHERiPTHR14272:SF3. PTHR14272:SF3. 1 hit.
    PfamiPF06031. SERTA. 1 hit.
    [Graphical view]
    PROSITEiPS51053. SERTA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9NUC0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTLVLSMNRF CEPIVSEGAA EIAGYQTLWE ADSYGGPSPP GPAQAPLQGD    50
    RGAGPPLAGS HYRGISNPIT TSKITYFKRK YVEEEDFHPP LSSCSHKTIS 100
    IFEERAHILY MSLEKLKFID DPEVYLRRSV LINNLMKRIH GEIIMQNNWC 150
    FPACSFNGTS AQEWFMAQDC PYRKRPRMAK EECEKFHACC FYQECGGHYL 200
    NLPLSVNANV GSASTAASSP SASSSSSSSS SSPPLPLPSC SRQVDFDVGS 250
    ASIYKSDGQI PANEIFVTNV RSLGVQEKAK LNDEKANDDT NRDGGPLSHE 300
    PVGNDLAFEC KGQFYDYFET GYNERNNVNE SWKKSLRKKE ASPPSNKLCC 350
    SKGSKI 356
    Length:356
    Mass (Da):39,348
    Last modified:October 1, 2000 - v1
    Checksum:iAC08F5241EFECE74
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK315386 mRNA. Translation: BAG37779.1.
    AL035414 Genomic DNA. Translation: CAB81635.1.
    CH471100 Genomic DNA. Translation: EAW93433.1.
    BC012083 mRNA. Translation: AAH12083.1.
    CCDSiCCDS1494.1.
    RefSeqiNP_062551.1. NM_019605.3.
    UniGeneiHs.600545.

    Genome annotation databases

    EnsembliENST00000367012; ENSP00000355979; ENSG00000082497.
    GeneIDi56256.
    KEGGihsa:56256.
    UCSCiuc001hhy.3. human.

    Polymorphism databases

    DMDMi74752974.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK315386 mRNA. Translation: BAG37779.1 .
    AL035414 Genomic DNA. Translation: CAB81635.1 .
    CH471100 Genomic DNA. Translation: EAW93433.1 .
    BC012083 mRNA. Translation: AAH12083.1 .
    CCDSi CCDS1494.1.
    RefSeqi NP_062551.1. NM_019605.3.
    UniGenei Hs.600545.

    3D structure databases

    ProteinModelPortali Q9NUC0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 121121. 4 interactions.
    IntActi Q9NUC0. 3 interactions.
    STRINGi 9606.ENSP00000355979.

    Polymorphism databases

    DMDMi 74752974.

    Proteomic databases

    PaxDbi Q9NUC0.
    PRIDEi Q9NUC0.

    Protocols and materials databases

    DNASUi 56256.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000367012 ; ENSP00000355979 ; ENSG00000082497 .
    GeneIDi 56256.
    KEGGi hsa:56256.
    UCSCi uc001hhy.3. human.

    Organism-specific databases

    CTDi 56256.
    GeneCardsi GC01P210406.
    HGNCi HGNC:25236. SERTAD4.
    HPAi HPA027344.
    HPA028514.
    neXtProti NX_Q9NUC0.
    PharmGKBi PA134897438.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG25597.
    HOGENOMi HOG000154425.
    HOVERGENi HBG108514.
    InParanoidi Q9NUC0.
    OMAi IHGEIIM.
    OrthoDBi EOG77Q4X1.
    PhylomeDBi Q9NUC0.
    TreeFami TF336235.

    Miscellaneous databases

    GenomeRNAii 56256.
    NextBioi 61901.
    PROi Q9NUC0.

    Gene expression databases

    Bgeei Q9NUC0.
    CleanExi HS_SERTAD4.
    Genevestigatori Q9NUC0.

    Family and domain databases

    InterProi IPR009263. SERTA_dom.
    IPR029708. SERTAD4.
    [Graphical view ]
    PANTHERi PTHR14272:SF3. PTHR14272:SF3. 1 hit.
    Pfami PF06031. SERTA. 1 hit.
    [Graphical view ]
    PROSITEi PS51053. SERTA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Corpus callosum.
    2. "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
      , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
      Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Kidney.

    Entry informationi

    Entry nameiSRTD4_HUMAN
    AccessioniPrimary (citable) accession number: Q9NUC0
    Secondary accession number(s): B2RD32
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 87 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 1
      Human chromosome 1: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3