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Protein

SERTA domain-containing protein 4

Gene

SERTAD4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
SERTA domain-containing protein 4
Gene namesi
Name:SERTAD4
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000082497.11
HGNCiHGNC:25236 SERTAD4
neXtProtiNX_Q9NUC0

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000082497
PharmGKBiPA134897438

Polymorphism and mutation databases

BioMutaiSERTAD4
DMDMi74752974

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003141391 – 356SERTA domain-containing protein 4Add BLAST356

Proteomic databases

PaxDbiQ9NUC0
PeptideAtlasiQ9NUC0
PRIDEiQ9NUC0
ProteomicsDBi82663

PTM databases

iPTMnetiQ9NUC0
PhosphoSitePlusiQ9NUC0

Expressioni

Gene expression databases

BgeeiENSG00000082497
CleanExiHS_SERTAD4
GenevisibleiQ9NUC0 HS

Organism-specific databases

HPAiHPA027344
HPA028514

Interactioni

Protein-protein interaction databases

BioGridi121121, 16 interactors
IntActiQ9NUC0, 6 interactors
STRINGi9606.ENSP00000355979

Structurei

3D structure databases

ProteinModelPortaliQ9NUC0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini101 – 147SERTAPROSITE-ProRule annotationAdd BLAST47

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi212 – 241Ser-richAdd BLAST30

Phylogenomic databases

eggNOGiENOG410IE5V Eukaryota
ENOG4111FEG LUCA
GeneTreeiENSGT00530000063876
HOGENOMiHOG000154425
HOVERGENiHBG108514
InParanoidiQ9NUC0
OMAiIHGEIIM
OrthoDBiEOG091G0BXM
PhylomeDBiQ9NUC0
TreeFamiTF336235

Family and domain databases

InterProiView protein in InterPro
IPR009263 SERTA_dom
IPR029708 SERTAD4
PANTHERiPTHR14272:SF4 PTHR14272:SF4, 1 hit
PfamiView protein in Pfam
PF06031 SERTA, 1 hit
PROSITEiView protein in PROSITE
PS51053 SERTA, 1 hit

Sequencei

Sequence statusi: Complete.

Q9NUC0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLVLSMNRF CEPIVSEGAA EIAGYQTLWE ADSYGGPSPP GPAQAPLQGD
60 70 80 90 100
RGAGPPLAGS HYRGISNPIT TSKITYFKRK YVEEEDFHPP LSSCSHKTIS
110 120 130 140 150
IFEERAHILY MSLEKLKFID DPEVYLRRSV LINNLMKRIH GEIIMQNNWC
160 170 180 190 200
FPACSFNGTS AQEWFMAQDC PYRKRPRMAK EECEKFHACC FYQECGGHYL
210 220 230 240 250
NLPLSVNANV GSASTAASSP SASSSSSSSS SSPPLPLPSC SRQVDFDVGS
260 270 280 290 300
ASIYKSDGQI PANEIFVTNV RSLGVQEKAK LNDEKANDDT NRDGGPLSHE
310 320 330 340 350
PVGNDLAFEC KGQFYDYFET GYNERNNVNE SWKKSLRKKE ASPPSNKLCC

SKGSKI
Length:356
Mass (Da):39,348
Last modified:October 1, 2000 - v1
Checksum:iAC08F5241EFECE74
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK315386 mRNA Translation: BAG37779.1
AL035414 Genomic DNA No translation available.
CH471100 Genomic DNA Translation: EAW93433.1
BC012083 mRNA Translation: AAH12083.1
CCDSiCCDS1494.1
RefSeqiNP_062551.1, NM_019605.3
UniGeneiHs.600545

Genome annotation databases

EnsembliENST00000367012; ENSP00000355979; ENSG00000082497
ENST00000630425; ENSP00000486369; ENSG00000281230
GeneIDi56256
KEGGihsa:56256
UCSCiuc001hhy.4 human

Similar proteinsi

Entry informationi

Entry nameiSRTD4_HUMAN
AccessioniPrimary (citable) accession number: Q9NUC0
Secondary accession number(s): B2RD32
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 1, 2000
Last modified: June 20, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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