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Protein

LYR motif-containing protein 2

Gene

LYRM2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
LYR motif-containing protein 2
Gene namesi
Name:LYRM2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000083099.10
HGNCiHGNC:25229 LYRM2
neXtProtiNX_Q9NU23

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000083099
PharmGKBiPA162394751

Polymorphism and mutation databases

BioMutaiLYRM2
DMDMi74734344

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002511751 – 88LYR motif-containing protein 2Add BLAST88

Proteomic databases

EPDiQ9NU23
MaxQBiQ9NU23
PaxDbiQ9NU23
PeptideAtlasiQ9NU23
PRIDEiQ9NU23
TopDownProteomicsiQ9NU23

PTM databases

iPTMnetiQ9NU23
PhosphoSitePlusiQ9NU23

Expressioni

Gene expression databases

BgeeiENSG00000083099
CleanExiHS_LYRM2
ExpressionAtlasiQ9NU23 baseline and differential
GenevisibleiQ9NU23 HS

Organism-specific databases

HPAiHPA063932

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
FAM9BQ8IZU03EBI-10313813,EBI-10175124

Protein-protein interaction databases

BioGridi121461, 11 interactors
IntActiQ9NU23, 1 interactor
STRINGi9606.ENSP00000430025

Structurei

3D structure databases

ProteinModelPortaliQ9NU23
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I LYR family.Curated

Phylogenomic databases

eggNOGiENOG410J39U Eukaryota
ENOG411277T LUCA
GeneTreeiENSGT00390000002957
HOVERGENiHBG056773
InParanoidiQ9NU23
OMAiAIRMMIT
PhylomeDBiQ9NU23
TreeFamiTF323797

Family and domain databases

InterProiView protein in InterPro
IPR008011 Complex1_LYR
IPR026868 Lyrm2
PANTHERiPTHR13675 PTHR13675, 1 hit
PfamiView protein in Pfam
PF05347 Complex1_LYR, 1 hit

Sequencei

Sequence statusi: Complete.

Q9NU23-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAASRLPPAT LTLKQFVRRQ QVLLLYRRIL QTIRQVPNDS DRKYLKDWAR
60 70 80
EEFRRNKSAT EEDTIRMMIT QGNMQLKELE KTLALAKS
Length:88
Mass (Da):10,449
Last modified:October 1, 2000 - v1
Checksum:i33F3189D286A95A0
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_05041734R → W. Corresponds to variant dbSNP:rs11553069Ensembl.1
Natural variantiVAR_03409946K → E1 PublicationCorresponds to variant dbSNP:rs34012596Ensembl.1
Natural variantiVAR_05041860T → P. Corresponds to variant dbSNP:rs1055889Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK311948 mRNA Translation: BAG34889.1
CH471051 Genomic DNA Translation: EAW48547.1
CH471051 Genomic DNA Translation: EAW48549.1
BC009782 mRNA Translation: AAH09782.1
BC104668 mRNA Translation: AAI04669.1
CCDSiCCDS5023.1
RefSeqiNP_065199.1, NM_020466.4
UniGeneiHs.177275

Genome annotation databases

EnsembliENST00000523377; ENSP00000430025; ENSG00000083099
GeneIDi57226
KEGGihsa:57226
UCSCiuc003pnm.4 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiLYRM2_HUMAN
AccessioniPrimary (citable) accession number: Q9NU23
Secondary accession number(s): B2R4U2, E1P517
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: October 1, 2000
Last modified: May 23, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

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