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Protein

RNA-binding protein 12

Gene

RBM12

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • nucleotide binding Source: InterPro
  • poly(A) RNA binding Source: UniProtKB
Complete GO annotation...

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA-binding protein 12
Alternative name(s):
RNA-binding motif protein 12
SH3/WW domain anchor protein in the nucleus
Short name:
SWAN
Gene namesi
Name:RBM12
Synonyms:KIAA0765
ORF Names:HRIHFB2091
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

HGNCiHGNC:9898. RBM12.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA34261.

Polymorphism and mutation databases

BioMutaiRBM12.
DMDMi30173387.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 932932RNA-binding protein 12PRO_0000081770Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei420 – 4201PhosphoserineCombined sources
Modified residuei422 – 4221PhosphoserineCombined sources
Modified residuei424 – 4241PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9NTZ6.
MaxQBiQ9NTZ6.
PaxDbiQ9NTZ6.
PeptideAtlasiQ9NTZ6.
PRIDEiQ9NTZ6.

PTM databases

iPTMnetiQ9NTZ6.
PhosphoSiteiQ9NTZ6.

Expressioni

Gene expression databases

BgeeiQ9NTZ6.
CleanExiHS_RBM12.
ExpressionAtlasiQ9NTZ6. baseline and differential.
GenevisibleiQ9NTZ6. HS.

Organism-specific databases

HPAiHPA043258.
HPA043621.

Interactioni

Protein-protein interaction databases

BioGridi115440. 38 interactions.
IntActiQ9NTZ6. 6 interactions.
MINTiMINT-1366084.
STRINGi9606.ENSP00000352668.

Structurei

Secondary structure

1
932
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi301 – 3044Combined sources
Beta strandi305 – 3095Combined sources
Helixi317 – 3237Combined sources
Turni324 – 3263Combined sources
Beta strandi331 – 3344Combined sources
Beta strandi344 – 3496Combined sources
Helixi353 – 3619Combined sources
Turni362 – 3643Combined sources
Beta strandi373 – 3764Combined sources
Helixi379 – 3868Combined sources
Beta strandi431 – 4355Combined sources
Helixi443 – 4497Combined sources
Turni457 – 4593Combined sources
Beta strandi461 – 4644Combined sources
Beta strandi468 – 48114Combined sources
Helixi482 – 4887Combined sources
Beta strandi500 – 5056Combined sources
Helixi507 – 52115Combined sources
Beta strandi545 – 5506Combined sources
Helixi557 – 5637Combined sources
Turni564 – 5663Combined sources
Beta strandi574 – 5763Combined sources
Beta strandi588 – 5914Combined sources
Helixi595 – 6017Combined sources
Helixi602 – 6043Combined sources
Beta strandi606 – 6094Combined sources
Beta strandi612 – 6198Combined sources
Helixi621 – 6299Combined sources
Beta strandi856 – 8616Combined sources
Helixi869 – 8757Combined sources
Turni876 – 8805Combined sources
Beta strandi887 – 8904Combined sources
Beta strandi896 – 90611Combined sources
Helixi907 – 91711Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1WELNMR-A412-522[»]
2CPYNMR-A536-636[»]
2DNNNMR-A295-390[»]
2EK1X-ray2.00A/B/C/D/E/F/G/H848-929[»]
2EK6X-ray2.38A/B/C/D848-929[»]
ProteinModelPortaliQ9NTZ6.
SMRiQ9NTZ6. Positions 289-390, 417-523, 538-638, 854-929.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9NTZ6.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini304 – 37976RRM 1PROSITE-ProRule annotationAdd
BLAST
Domaini430 – 50778RRM 2PROSITE-ProRule annotationAdd
BLAST
Domaini856 – 93277RRM 3PROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi159 – 301143Pro-richAdd
BLAST
Compositional biasi186 – 1949Poly-Pro
Compositional biasi631 – 855225Pro-richAdd
BLAST
Compositional biasi635 – 854220Gly-richAdd
BLAST

Sequence similaritiesi

Contains 3 RRM (RNA recognition motif) domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG4307. Eukaryota.
ENOG4111WZ9. LUCA.
GeneTreeiENSGT00760000119102.
HOVERGENiHBG057691.
InParanoidiQ9NTZ6.
OMAiISCFIRC.
OrthoDBiEOG77DJ57.
PhylomeDBiQ9NTZ6.
TreeFamiTF331899.

Family and domain databases

Gene3Di3.30.70.330. 5 hits.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 3 hits.
[Graphical view]
SMARTiSM00360. RRM. 4 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 5 hits.
PROSITEiPS50102. RRM. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9NTZ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVVIRLQGL PIVAGTMDIR HFFSGLTIPD GGVHIVGGEL GEAFIVFATD
60 70 80 90 100
EDARLGMMRT GGTIKGSKVT LLLSSKTEMQ NMIELSRRRF ETANLDIPPA
110 120 130 140 150
NASRSGPPPS SGMSSRVNLP TTVSNFNNPS PSVVTATTSV HESNKNIQTF
160 170 180 190 200
STASVGTAPP NMGASFGSPT FSSTVPSTAS PMNTVPPPPI PPIPAMPSLP
210 220 230 240 250
PMPSIPPIPV PPPVPTLPPV PPVPPIPPVP SVPPMTPLPP MSGMPPLNPP
260 270 280 290 300
PVAPLPAGMN GSGAPMNLNN NLNPMFLGPL NPVNPIQMNS QSSVKPLPIN
310 320 330 340 350
PDDLYVSVHG MPFSAMENDV RDFFHGLRVD AVHLLKDHVG RNNGNGLVKF
360 370 380 390 400
LSPQDTFEAL KRNRMLMIQR YVEVSPATER QWVAAGGHIT FKQNMGPSGQ
410 420 430 440 450
THPPPQTLPR SKSPSGQKRS RSRSPHEAGF CVYLKGLPFE AENKHVIDFF
460 470 480 490 500
KKLDIVEDSI YIAYGPNGKA TGEGFVEFRN EADYKAALCR HKQYMGNRFI
510 520 530 540 550
QVHPITKKGM LEKIDMIRKR LQNFSYDQRE MILNPEGDVN SAKVCAHITN
560 570 580 590 600
IPFSITKMDV LQFLEGIPVD ENAVHVLVDN NGQGLGQALV QFKNEDDARK
610 620 630 640 650
SERLHRKKLN GREAFVHVVT LEDMREIEKN PPAQGKKGLK MPVPGNPAVP
660 670 680 690 700
GMPNAGLPGV GLPSAGLPGA GLPSTGLPGS AITSAGLPGA GMPSAGIPSA
710 720 730 740 750
GGEEHAFLTV GSKEANNGPP FNFPGNFGGS NAFGPPIPPP GLGGGAFGDA
760 770 780 790 800
RPGMPSVGNS GLPGLGLDVP GFGGGPNNLS GPSGFGGGPQ NFGNGPGSLG
810 820 830 840 850
GPPGFGSGPP GLGSAPGHLG GPPAFGPGPG PGPGPGPIHI GGPPGFASSS
860 870 880 890 900
GKPGPTVIKV QNMPFTVSID EILDFFYGYQ VIPGSVCLKY NEKGMPTGEA
910 920 930
MVAFESRDEA TAAVIDLNDR PIGSRKVKLV LG
Length:932
Mass (Da):97,395
Last modified:October 1, 2000 - v1
Checksum:i10623E1EBCC93FC5
GO

Sequence cautioni

The sequence BAA34485.2 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti601 – 6011S → T in CAC20441 (PubMed:11435693).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti572 – 5721N → S.
Corresponds to variant rs17092928 [ dbSNP | Ensembl ].
VAR_052217
Natural varianti921 – 9211P → L.
Corresponds to variant rs6121012 [ dbSNP | Ensembl ].
VAR_052218

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ289772 mRNA. Translation: CAC20441.1.
AF345332 mRNA. Translation: AAL83752.1.
AF345335 Genomic DNA. Translation: AAL83755.1.
AF393214 mRNA. Translation: AAM73682.1.
AB018308 mRNA. Translation: BAA34485.2. Different initiation.
AK092239 mRNA. Translation: BAG52504.1.
AL109827 Genomic DNA. Translation: CAB87611.1.
CH471077 Genomic DNA. Translation: EAW76182.1.
CH471077 Genomic DNA. Translation: EAW76184.1.
CH471077 Genomic DNA. Translation: EAW76188.1.
BC012787 mRNA. Translation: AAH12787.1.
BC013981 mRNA. Translation: AAH13981.1.
AL834472 mRNA. Translation: CAD39131.1.
AB015336 mRNA. Translation: BAA34794.1.
CCDSiCCDS13261.1.
RefSeqiNP_001185767.1. NM_001198838.1.
NP_001185769.1. NM_001198840.1.
NP_006038.2. NM_006047.5.
NP_690051.1. NM_152838.3.
UniGeneiHs.700188.

Genome annotation databases

EnsembliENST00000359646; ENSP00000352668; ENSG00000244462.
ENST00000374104; ENSP00000363217; ENSG00000244462.
ENST00000374114; ENSP00000363228; ENSG00000244462.
GeneIDi10137.
KEGGihsa:10137.
UCSCiuc002xdq.4. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ289772 mRNA. Translation: CAC20441.1.
AF345332 mRNA. Translation: AAL83752.1.
AF345335 Genomic DNA. Translation: AAL83755.1.
AF393214 mRNA. Translation: AAM73682.1.
AB018308 mRNA. Translation: BAA34485.2. Different initiation.
AK092239 mRNA. Translation: BAG52504.1.
AL109827 Genomic DNA. Translation: CAB87611.1.
CH471077 Genomic DNA. Translation: EAW76182.1.
CH471077 Genomic DNA. Translation: EAW76184.1.
CH471077 Genomic DNA. Translation: EAW76188.1.
BC012787 mRNA. Translation: AAH12787.1.
BC013981 mRNA. Translation: AAH13981.1.
AL834472 mRNA. Translation: CAD39131.1.
AB015336 mRNA. Translation: BAA34794.1.
CCDSiCCDS13261.1.
RefSeqiNP_001185767.1. NM_001198838.1.
NP_001185769.1. NM_001198840.1.
NP_006038.2. NM_006047.5.
NP_690051.1. NM_152838.3.
UniGeneiHs.700188.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1WELNMR-A412-522[»]
2CPYNMR-A536-636[»]
2DNNNMR-A295-390[»]
2EK1X-ray2.00A/B/C/D/E/F/G/H848-929[»]
2EK6X-ray2.38A/B/C/D848-929[»]
ProteinModelPortaliQ9NTZ6.
SMRiQ9NTZ6. Positions 289-390, 417-523, 538-638, 854-929.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi115440. 38 interactions.
IntActiQ9NTZ6. 6 interactions.
MINTiMINT-1366084.
STRINGi9606.ENSP00000352668.

PTM databases

iPTMnetiQ9NTZ6.
PhosphoSiteiQ9NTZ6.

Polymorphism and mutation databases

BioMutaiRBM12.
DMDMi30173387.

Proteomic databases

EPDiQ9NTZ6.
MaxQBiQ9NTZ6.
PaxDbiQ9NTZ6.
PeptideAtlasiQ9NTZ6.
PRIDEiQ9NTZ6.

Protocols and materials databases

DNASUi10137.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000359646; ENSP00000352668; ENSG00000244462.
ENST00000374104; ENSP00000363217; ENSG00000244462.
ENST00000374114; ENSP00000363228; ENSG00000244462.
GeneIDi10137.
KEGGihsa:10137.
UCSCiuc002xdq.4. human.

Organism-specific databases

CTDi10137.
GeneCardsiRBM12.
HGNCiHGNC:9898. RBM12.
HPAiHPA043258.
HPA043621.
MIMi607179. gene.
neXtProtiNX_Q9NTZ6.
PharmGKBiPA34261.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4307. Eukaryota.
ENOG4111WZ9. LUCA.
GeneTreeiENSGT00760000119102.
HOVERGENiHBG057691.
InParanoidiQ9NTZ6.
OMAiISCFIRC.
OrthoDBiEOG77DJ57.
PhylomeDBiQ9NTZ6.
TreeFamiTF331899.

Miscellaneous databases

EvolutionaryTraceiQ9NTZ6.
GeneWikiiRBM12.
GenomeRNAii10137.
NextBioi38349.
PROiQ9NTZ6.
SOURCEiSearch...

Gene expression databases

BgeeiQ9NTZ6.
CleanExiHS_RBM12.
ExpressionAtlasiQ9NTZ6. baseline and differential.
GenevisibleiQ9NTZ6. HS.

Family and domain databases

Gene3Di3.30.70.330. 5 hits.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 3 hits.
[Graphical view]
SMARTiSM00360. RRM. 4 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 5 hits.
PROSITEiPS50102. RRM. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "cDNA cloning, chromosomal assignment, and genomic structure of a human gene encoding a novel member of the RBM family."
    Stover C.M., Gradl G., Jentsch I., Speicher M.R., Wieser R., Schwaeble W.J.
    Cytogenet. Cell Genet. 92:225-230(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Leukemia.
  2. "Identification of SWAN as a novel hnRNP-like adaptor protein with multiple domains and broadly expressed in mammalian tissues."
    Huang C.-H.
    Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
  3. "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
    Nagase T., Ishikawa K., Suyama M., Kikuno R., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
    DNA Res. 5:277-286(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.
  4. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
    Nakajima D., Okazaki N., Yamakawa H., Kikuno R., Ohara O., Nagase T.
    DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: SEQUENCE REVISION.
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  6. "The DNA sequence and comparative analysis of human chromosome 20."
    Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
    , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
    Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Placenta.
  9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 270-932.
    Tissue: Melanoma.
  10. "Selection system for genes encoding nuclear-targeted proteins."
    Ueki N., Oda T., Kondo M., Yano K., Noguchi T., Muramatsu M.-A.
    Nat. Biotechnol. 16:1338-1342(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 557-932, SUBCELLULAR LOCATION.
    Tissue: Brain.
  11. "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry."
    Brill L.M., Salomon A.R., Ficarro S.B., Mukherji M., Stettler-Gill M., Peters E.C.
    Anal. Chem. 76:2763-2772(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  12. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
    Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
    Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  13. "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
    Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D., Yates J.R. III
    J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-424, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  14. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-420; SER-422 AND SER-424, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  15. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  16. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-422 AND SER-424, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  17. "Solution structure of RNA binding domains in RNA-binding protein 12."
    RIKEN structural genomics initiative (RSGI)
    Submitted (OCT-2006) to the PDB data bank
    Cited for: STRUCTURE BY NMR OF 290-638.

Entry informationi

Entry nameiRBM12_HUMAN
AccessioniPrimary (citable) accession number: Q9NTZ6
Secondary accession number(s): B3KRU2
, E1P5R6, O94865, Q8N3B1, Q9H196
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 23, 2003
Last sequence update: October 1, 2000
Last modified: May 11, 2016
This is version 147 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.