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Protein

Testis-expressed sequence 40 protein

Gene

TEX40

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in late spermatogenesis.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Differentiation, Spermatogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Testis-expressed sequence 40 protein
Gene namesi
Name:TEX40
Synonyms:C11orf20
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:19231. TEX40.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA164716726.

Polymorphism and mutation databases

BioMutaiTEX40.
DMDMi74719331.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 200200Testis-expressed sequence 40 proteinPRO_0000349322Add
BLAST

Proteomic databases

PaxDbiQ9NTU4.
PRIDEiQ9NTU4.

PTM databases

iPTMnetiQ9NTU4.
PhosphoSiteiQ9NTU4.

Expressioni

Gene expression databases

BgeeiQ9NTU4.

Organism-specific databases

HPAiHPA052822.

Interactioni

Protein-protein interaction databases

MINTiMINT-4715815.
STRINGi9606.ENSP00000330877.

Structurei

3D structure databases

ProteinModelPortaliQ9NTU4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IX8U. Eukaryota.
ENOG411141E. LUCA.
HOGENOMiHOG000111720.
InParanoidiQ9NTU4.
PhylomeDBiQ9NTU4.

Sequencei

Sequence statusi: Complete.

Q9NTU4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEKPSKVSL KSSDRQGSDE ESVHSDTRDL WTTTTLSQAQ LNMPLSEVCE
60 70 80 90 100
GFDEEGRNIS KTRGWHSPGR GSLDEGYKAS HKPEELDEHA LVELELHRGS
110 120 130 140 150
SMEINLGEKD TASQIEAEKS SSMSSLNIAK HMPHRAYWAE QQSRLPLPLM
160 170 180 190 200
ELMENEALEI LTKALRSYQL GIGRDHFLTK ELQRYIEGLK KRRSKRLYVN
Length:200
Mass (Da):22,839
Last modified:October 1, 2000 - v1
Checksum:i25F6EC8873330DCB
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti68 – 681P → L.
Corresponds to variant rs2286614 [ dbSNP | Ensembl ].
VAR_046370

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL117564 mRNA. Translation: CAB55995.2.
PIRiT17305.
RefSeqiNP_001034585.1. NM_001039496.1.
UniGeneiHs.97174.

Genome annotation databases

EnsembliENST00000328404; ENSP00000330877; ENSG00000219435.
GeneIDi25858.
KEGGihsa:25858.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL117564 mRNA. Translation: CAB55995.2.
PIRiT17305.
RefSeqiNP_001034585.1. NM_001039496.1.
UniGeneiHs.97174.

3D structure databases

ProteinModelPortaliQ9NTU4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-4715815.
STRINGi9606.ENSP00000330877.

PTM databases

iPTMnetiQ9NTU4.
PhosphoSiteiQ9NTU4.

Polymorphism and mutation databases

BioMutaiTEX40.
DMDMi74719331.

Proteomic databases

PaxDbiQ9NTU4.
PRIDEiQ9NTU4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000328404; ENSP00000330877; ENSG00000219435.
GeneIDi25858.
KEGGihsa:25858.

Organism-specific databases

CTDi25858.
GeneCardsiTEX40.
HGNCiHGNC:19231. TEX40.
HPAiHPA052822.
neXtProtiNX_Q9NTU4.
PharmGKBiPA164716726.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IX8U. Eukaryota.
ENOG411141E. LUCA.
HOGENOMiHOG000111720.
InParanoidiQ9NTU4.
PhylomeDBiQ9NTU4.

Miscellaneous databases

NextBioi47219.
PROiQ9NTU4.

Gene expression databases

BgeeiQ9NTU4.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Kidney.
  2. Cited for: IDENTIFICATION.

Entry informationi

Entry nameiTEX40_HUMAN
AccessioniPrimary (citable) accession number: Q9NTU4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: October 1, 2000
Last modified: March 16, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

A report observed N-glycosylation at Asn-58 (PubMed:19139490). However, as the protein is not predicted to localize in an extracellular compartment of the cell, additional evidences are required to confirm this result.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.