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Protein

Sister chromatid cohesion protein PDS5 homolog B

Gene

PDS5B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells.3 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi1249 – 1261A.T hook 1Sequence analysisAdd BLAST13
DNA bindingi1287 – 1299A.T hook 2Sequence analysisAdd BLAST13
DNA bindingi1372 – 1384A.T hook 3Sequence analysisAdd BLAST13

GO - Molecular functioni

  • ATP binding Source: ProtInc
  • DNA binding Source: ProtInc

GO - Biological processi

  • cell division Source: UniProtKB-KW
  • cell proliferation Source: ProtInc
  • DNA repair Source: GO_Central
  • mitotic sister chromatid cohesion Source: UniProtKB
  • negative regulation of cell proliferation Source: UniProtKB
  • regulation of cell proliferation Source: MGI
  • sister chromatid cohesion Source: Reactome
Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, Mitosis

Enzyme and pathway databases

ReactomeiR-HSA-2467813. Separation of Sister Chromatids.
R-HSA-2468052. Establishment of Sister Chromatid Cohesion.
R-HSA-2470946. Cohesin Loading onto Chromatin.
R-HSA-2500257. Resolution of Sister Chromatid Cohesion.

Names & Taxonomyi

Protein namesi
Recommended name:
Sister chromatid cohesion protein PDS5 homolog B
Alternative name(s):
Androgen-induced proliferation inhibitor
Androgen-induced prostate proliferative shutoff-associated protein AS3
Gene namesi
Name:PDS5B
Synonyms:APRIN, AS3Imported, KIAA0979Imported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 13

Organism-specific databases

HGNCiHGNC:20418. PDS5B.

Subcellular locationi

  • Nucleus By similarity

GO - Cellular componenti

  • chromatin Source: UniProtKB
  • chromosome Source: Reactome
  • chromosome, centromeric region Source: Reactome
  • cytosol Source: Reactome
  • nucleoplasm Source: HPA
  • nucleus Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

DisGeNETi23047.
OpenTargetsiENSG00000083642.
PharmGKBiPA162399098.

Polymorphism and mutation databases

BioMutaiPDS5B.
DMDMi74725312.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002874241 – 1447Sister chromatid cohesion protein PDS5 homolog BAdd BLAST1447

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1136N6-acetyllysineCombined sources1
Modified residuei1140PhosphoserineCombined sources1
Modified residuei1162PhosphoserineCombined sources1
Modified residuei1166PhosphoserineCombined sources1
Modified residuei1176PhosphoserineCombined sources1
Modified residuei1182PhosphoserineCombined sources1
Modified residuei1191PhosphoserineCombined sources1
Modified residuei1255PhosphothreonineCombined sources1
Modified residuei1257PhosphoserineCombined sources1
Modified residuei1259PhosphoserineCombined sources1
Modified residuei1283PhosphoserineCombined sources1
Modified residuei1319PhosphoserineCombined sources1
Modified residuei1334PhosphoserineCombined sources1
Modified residuei1358PhosphoserineCombined sources1
Modified residuei1366PhosphoserineBy similarity1
Modified residuei1367PhosphothreonineCombined sources1
Modified residuei1369PhosphoserineBy similarity1
Modified residuei1370PhosphothreonineCombined sources1
Modified residuei1381PhosphothreonineCombined sources1
Modified residuei1383PhosphoserineCombined sources1
Modified residuei1417PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ9NTI5.
MaxQBiQ9NTI5.
PaxDbiQ9NTI5.
PeptideAtlasiQ9NTI5.
PRIDEiQ9NTI5.

PTM databases

iPTMnetiQ9NTI5.
PhosphoSitePlusiQ9NTI5.

Expressioni

Tissue specificityi

Widely expressed.1 Publication

Inductioni

By the synthetic androgen R1881 in prostate carcinoma cells undergoing proliferative arrest. Maximum levels occur 18-20 hours after androgen exposure.1 Publication

Gene expression databases

BgeeiENSG00000083642.
CleanExiHS_PDS5B.
ExpressionAtlasiQ9NTI5. baseline and differential.
GenevisibleiQ9NTI5. HS.

Organism-specific databases

HPAiHPA039513.
HPA040015.

Interactioni

Subunit structurei

Interacts with the cohesin complex. Interacts with RAD21; the interaction is direct. Interacts with WAPL (via FGF motifs) or CDCA5 (via the FGF motif); the interaction is direct, cohesin-dependent and competitive (Probable).3 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
BRCA2P5158726EBI-1175604,EBI-79792
RAD21O602164EBI-1175604,EBI-80739
SMC3Q9UQE77EBI-1175604,EBI-80718
STAG1Q8WVM73EBI-1175604,EBI-1175097
STAG2Q8N3U43EBI-1175604,EBI-1057252
WAPLQ7Z5K29EBI-1175604,EBI-1022242

Protein-protein interaction databases

BioGridi116685. 52 interactors.
DIPiDIP-35420N.
IntActiQ9NTI5. 23 interactors.
MINTiMINT-3073997.
STRINGi9606.ENSP00000313851.

Structurei

Secondary structure

11447
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi24 – 26Combined sources3
Helixi28 – 44Combined sources17
Helixi50 – 63Combined sources14
Helixi66 – 69Combined sources4
Helixi74 – 91Combined sources18
Helixi100 – 113Combined sources14
Helixi114 – 118Combined sources5
Helixi125 – 138Combined sources14
Helixi140 – 146Combined sources7
Helixi150 – 164Combined sources15
Helixi171 – 186Combined sources16
Beta strandi187 – 189Combined sources3
Helixi193 – 200Combined sources8
Helixi201 – 203Combined sources3
Helixi205 – 210Combined sources6
Helixi212 – 224Combined sources13
Helixi226 – 240Combined sources15
Helixi252 – 254Combined sources3
Helixi255 – 265Combined sources11
Helixi267 – 270Combined sources4
Turni271 – 273Combined sources3
Helixi274 – 280Combined sources7
Helixi286 – 301Combined sources16
Helixi307 – 310Combined sources4
Helixi312 – 319Combined sources8
Helixi320 – 323Combined sources4
Helixi327 – 343Combined sources17
Helixi345 – 350Combined sources6
Helixi352 – 358Combined sources7
Helixi364 – 380Combined sources17
Helixi382 – 384Combined sources3
Helixi387 – 396Combined sources10
Helixi402 – 419Combined sources18
Helixi427 – 432Combined sources6
Turni433 – 435Combined sources3
Helixi436 – 442Combined sources7
Helixi443 – 445Combined sources3
Helixi449 – 461Combined sources13
Helixi470 – 481Combined sources12
Helixi486 – 514Combined sources29
Helixi519 – 533Combined sources15
Helixi539 – 555Combined sources17
Helixi557 – 567Combined sources11
Helixi573 – 585Combined sources13
Helixi596 – 608Combined sources13
Helixi615 – 629Combined sources15
Helixi634 – 638Combined sources5
Helixi642 – 659Combined sources18
Helixi662 – 664Combined sources3
Helixi667 – 677Combined sources11
Helixi682 – 695Combined sources14
Helixi699 – 702Combined sources4
Helixi704 – 720Combined sources17
Helixi723 – 736Combined sources14
Helixi740 – 754Combined sources15
Helixi761 – 763Combined sources3
Helixi764 – 776Combined sources13
Turni778 – 781Combined sources4
Helixi782 – 791Combined sources10
Helixi794 – 797Combined sources4
Helixi815 – 817Combined sources3
Helixi820 – 839Combined sources20
Helixi846 – 859Combined sources14
Turni860 – 862Combined sources3
Helixi872 – 890Combined sources19
Helixi893 – 896Combined sources4
Helixi901 – 908Combined sources8
Helixi909 – 912Combined sources4
Helixi916 – 931Combined sources16
Helixi937 – 939Combined sources3
Helixi941 – 948Combined sources8
Helixi952 – 975Combined sources24
Helixi980 – 984Combined sources5
Helixi988 – 990Combined sources3
Helixi991 – 1000Combined sources10
Helixi1011 – 1028Combined sources18
Helixi1036 – 1047Combined sources12
Beta strandi1053 – 1055Combined sources3
Helixi1059 – 1079Combined sources21
Beta strandi1081 – 1085Combined sources5
Turni1095 – 1097Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5HDTX-ray2.71A/B21-1120[»]
ProteinModelPortaliQ9NTI5.
SMRiQ9NTI5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati383 – 419HEATSequence analysisAdd BLAST37

Sequence similaritiesi

Belongs to the PDS5 family.Curated
Contains 3 A.T hook DNA-binding domains.Sequence analysis
Contains 1 HEAT repeat.Sequence analysis

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG1525. Eukaryota.
ENOG410XQW7. LUCA.
GeneTreeiENSGT00390000012488.
HOVERGENiHBG108241.
InParanoidiQ9NTI5.
KOiK11267.
OMAiMFRIVND.
OrthoDBiEOG091G00ZG.
PhylomeDBiQ9NTI5.
TreeFamiTF106415.

Family and domain databases

Gene3Di1.25.10.10. 4 hits.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 5 hits.

Sequences (5)i

Sequence statusi: Complete.

This entry describes 5 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 11 Publication (identifier: Q9NTI5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAHSKTRTND GKITYPPGVK EISDKISKEE MVRRLKMVVK TFMDMDQDSE
60 70 80 90 100
EEKELYLNLA LHLASDFFLK HPDKDVRLLV ACCLADIFRI YAPEAPYTSP
110 120 130 140 150
DKLKDIFMFI TRQLKGLEDT KSPQFNRYFY LLENIAWVKS YNICFELEDS
160 170 180 190 200
NEIFTQLYRT LFSVINNGHN QKVHMHMVDL MSSIICEGDT VSQELLDTVL
210 220 230 240 250
VNLVPAHKNL NKQAYDLAKA LLKRTAQAIE PYITNFFNQV LMLGKTSISD
260 270 280 290 300
LSEHVFDLIL ELYNIDSHLL LSVLPQLEFK LKSNDNEERL QVVKLLAKMF
310 320 330 340 350
GAKDSELASQ NKPLWQCYLG RFNDIHVPIR LECVKFASHC LMNHPDLAKD
360 370 380 390 400
LTEYLKVRSH DPEEAIRHDV IVSIVTAAKK DILLVNDHLL NFVRERTLDK
410 420 430 440 450
RWRVRKEAMM GLAQIYKKYA LQSAAGKDAA KQIAWIKDKL LHIYYQNSID
460 470 480 490 500
DRLLVERIFA QYMVPHNLET TERMKCLYYL YATLDLNAVK ALNEMWKCQN
510 520 530 540 550
LLRHQVKDLL DLIKQPKTDA SVKAIFSKVM VITRNLPDPG KAQDFMKKFT
560 570 580 590 600
QVLEDDEKIR KQLEVLVSPT CSCKQAEGCV REITKKLGNP KQPTNPFLEM
610 620 630 640 650
IKFLLERIAP VHIDTESISA LIKQVNKSID GTADDEDEGV PTDQAIRAGL
660 670 680 690 700
ELLKVLSFTH PISFHSAETF ESLLACLKMD DEKVAEAALQ IFKNTGSKIE
710 720 730 740 750
EDFPHIRSAL LPVLHHKSKK GPPRQAKYAI HCIHAIFSSK ETQFAQIFEP
760 770 780 790 800
LHKSLDPSNL EHLITPLVTI GHIALLAPDQ FAAPLKSLVA TFIVKDLLMN
810 820 830 840 850
DRLPGKKTTK LWVPDEEVSP ETMVKIQAIK MMVRWLLGMK NNHSKSGTST
860 870 880 890 900
LRLLTTILHS DGDLTEQGKI SKPDMSRLRL AAGSAIVKLA QEPCYHEIIT
910 920 930 940 950
LEQYQLCALA INDECYQVRQ VFAQKLHKGL SRLRLPLEYM AICALCAKDP
960 970 980 990 1000
VKERRAHARQ CLVKNINVRR EYLKQHAAVS EKLLSLLPEY VVPYTIHLLA
1010 1020 1030 1040 1050
HDPDYVKVQD IEQLKDVKEC LWFVLEILMA KNENNSHAFI RKMVENIKQT
1060 1070 1080 1090 1100
KDAQGPDDAK MNEKLYTVCD VAMNIIMSKS TTYSLESPKD PVLPARFFTQ
1110 1120 1130 1140 1150
PDKNFSNTKN YLPPEMKSFF TPGKPKTTNV LGAVNKPLSS AGKQSQTKSS
1160 1170 1180 1190 1200
RMETVSNASS SSNPSSPGRI KGRLDSSEMD HSENEDYTMS SPLPGKKSDK
1210 1220 1230 1240 1250
RDDSDLVRSE LEKPRGRKKT PVTEQEEKLG MDDLTKLVQE QKPKGSQRSR
1260 1270 1280 1290 1300
KRGHTASESD EQQWPEEKRL KEDILENEDE QNSPPKKGKR GRPPKPLGGG
1310 1320 1330 1340 1350
TPKEEPTMKT SKKGSKKKSG PPAPEEEEEE ERQSGNTEQK SKSKQHRVSR
1360 1370 1380 1390 1400
RAQQRAESPE SSAIESTQST PQKGRGRPSK TPSPSQPKKN VRVGRSKQAA
1410 1420 1430 1440
TKENDSSEEV DVFQGSSPVD DIPQEETEEE EVSTVNVRRR SAKRERR
Length:1,447
Mass (Da):164,667
Last modified:October 1, 2000 - v1
Checksum:i145C30308EA3EFD5
GO
Isoform 21 Publication (identifier: Q9NTI5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1392-1447: Missing.

Show »
Length:1,391
Mass (Da):158,280
Checksum:i9C5FD7A7F8C4A18F
GO
Isoform 31 Publication (identifier: Q9NTI5-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     491-529: ALNEMWKCQN...ASVKAIFSKV → YVSNIKFCSF...KCNLCSVNIV
     530-1447: Missing.

Note: No experimental confirmation available.Curated
Show »
Length:529
Mass (Da):61,437
Checksum:i05CDB3E2A92F46DD
GO
Isoform 41 Publication (identifier: Q9NTI5-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     105-122: DIFMFITRQLKGLEDTKS → ASTDLNNSKIDRYFDLSF
     123-1447: Missing.

Note: No experimental confirmation available.Curated
Show »
Length:122
Mass (Da):14,108
Checksum:iB8EAB2D511A217CB
GO
Isoform 51 Publication (identifier: Q9NTI5-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1230: Missing.
     1356-1447: Missing.

Note: No experimental confirmation available.Curated
Show »
Length:125
Mass (Da):14,281
Checksum:i492809836D3665D3
GO

Sequence cautioni

The sequence BAA76823 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti256F → S in AAD22134 (PubMed:10215036).Curated1
Sequence conflicti326H → N in AAH39256 (PubMed:15489334).Curated1
Sequence conflicti394R → G in AAD22134 (PubMed:10215036).Curated1
Sequence conflicti535N → S in AAD22134 (PubMed:10215036).Curated1
Sequence conflicti742T → A in AAD22134 (PubMed:10215036).Curated1
Sequence conflicti1115E → G in AAD22134 (PubMed:10215036).Curated1
Sequence conflicti1156S → G in AAD22134 (PubMed:10215036).Curated1
Sequence conflicti1197K → R in AAD22134 (PubMed:10215036).Curated1
Sequence conflicti1225Q → R in AAD22134 (PubMed:10215036).Curated1
Sequence conflicti1242K → R in AAD22134 (PubMed:10215036).Curated1
Sequence conflicti1359P → S in AAD22134 (PubMed:10215036).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0523961 – 1230Missing in isoform 5. 1 PublicationAdd BLAST1230
Alternative sequenceiVSP_052397105 – 122DIFMF…EDTKS → ASTDLNNSKIDRYFDLSF in isoform 4. 1 PublicationAdd BLAST18
Alternative sequenceiVSP_052398123 – 1447Missing in isoform 4. 1 PublicationAdd BLAST1325
Alternative sequenceiVSP_052399491 – 529ALNEM…IFSKV → YVSNIKFCSFHPLQYIGFYG KETTNTCILKCNLCSVNIV in isoform 3. 1 PublicationAdd BLAST39
Alternative sequenceiVSP_052400530 – 1447Missing in isoform 3. 1 PublicationAdd BLAST918
Alternative sequenceiVSP_0524011356 – 1447Missing in isoform 5. 1 PublicationAdd BLAST92
Alternative sequenceiVSP_0524021392 – 1447Missing in isoform 2. 1 PublicationAdd BLAST56

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U95825 mRNA. Translation: AAD22134.2.
AB023196 mRNA. Translation: BAA76823.2. Different initiation.
AK026889 mRNA. Translation: BAB15584.1.
AL137201 mRNA. Translation: CAB69911.1.
AL138820, Z75889 Genomic DNA. Translation: CAH73160.2.
Z75889, AL138820 Genomic DNA. Translation: CAI10806.2.
BC039256 mRNA. Translation: AAH39256.1.
BC070274 mRNA. Translation: AAH70274.1.
CCDSiCCDS41878.1. [Q9NTI5-1]
RefSeqiNP_055847.1. NM_015032.3. [Q9NTI5-1]
XP_016875939.1. XM_017020450.1. [Q9NTI5-1]
UniGeneiHs.744901.

Genome annotation databases

EnsembliENST00000315596; ENSP00000313851; ENSG00000083642. [Q9NTI5-1]
ENST00000450460; ENSP00000401619; ENSG00000083642. [Q9NTI5-2]
GeneIDi23047.
KEGGihsa:23047.
UCSCiuc010abf.4. human. [Q9NTI5-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U95825 mRNA. Translation: AAD22134.2.
AB023196 mRNA. Translation: BAA76823.2. Different initiation.
AK026889 mRNA. Translation: BAB15584.1.
AL137201 mRNA. Translation: CAB69911.1.
AL138820, Z75889 Genomic DNA. Translation: CAH73160.2.
Z75889, AL138820 Genomic DNA. Translation: CAI10806.2.
BC039256 mRNA. Translation: AAH39256.1.
BC070274 mRNA. Translation: AAH70274.1.
CCDSiCCDS41878.1. [Q9NTI5-1]
RefSeqiNP_055847.1. NM_015032.3. [Q9NTI5-1]
XP_016875939.1. XM_017020450.1. [Q9NTI5-1]
UniGeneiHs.744901.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5HDTX-ray2.71A/B21-1120[»]
ProteinModelPortaliQ9NTI5.
SMRiQ9NTI5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi116685. 52 interactors.
DIPiDIP-35420N.
IntActiQ9NTI5. 23 interactors.
MINTiMINT-3073997.
STRINGi9606.ENSP00000313851.

PTM databases

iPTMnetiQ9NTI5.
PhosphoSitePlusiQ9NTI5.

Polymorphism and mutation databases

BioMutaiPDS5B.
DMDMi74725312.

Proteomic databases

EPDiQ9NTI5.
MaxQBiQ9NTI5.
PaxDbiQ9NTI5.
PeptideAtlasiQ9NTI5.
PRIDEiQ9NTI5.

Protocols and materials databases

DNASUi23047.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000315596; ENSP00000313851; ENSG00000083642. [Q9NTI5-1]
ENST00000450460; ENSP00000401619; ENSG00000083642. [Q9NTI5-2]
GeneIDi23047.
KEGGihsa:23047.
UCSCiuc010abf.4. human. [Q9NTI5-1]

Organism-specific databases

CTDi23047.
DisGeNETi23047.
GeneCardsiPDS5B.
HGNCiHGNC:20418. PDS5B.
HPAiHPA039513.
HPA040015.
MIMi605333. gene.
neXtProtiNX_Q9NTI5.
OpenTargetsiENSG00000083642.
PharmGKBiPA162399098.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1525. Eukaryota.
ENOG410XQW7. LUCA.
GeneTreeiENSGT00390000012488.
HOVERGENiHBG108241.
InParanoidiQ9NTI5.
KOiK11267.
OMAiMFRIVND.
OrthoDBiEOG091G00ZG.
PhylomeDBiQ9NTI5.
TreeFamiTF106415.

Enzyme and pathway databases

ReactomeiR-HSA-2467813. Separation of Sister Chromatids.
R-HSA-2468052. Establishment of Sister Chromatid Cohesion.
R-HSA-2470946. Cohesin Loading onto Chromatin.
R-HSA-2500257. Resolution of Sister Chromatid Cohesion.

Miscellaneous databases

ChiTaRSiPDS5B. human.
GeneWikiiPDS5B.
GenomeRNAii23047.
PROiQ9NTI5.
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000083642.
CleanExiHS_PDS5B.
ExpressionAtlasiQ9NTI5. baseline and differential.
GenevisibleiQ9NTI5. HS.

Family and domain databases

Gene3Di1.25.10.10. 4 hits.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 5 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiPDS5B_HUMAN
AccessioniPrimary (citable) accession number: Q9NTI5
Secondary accession number(s): Q5R3S3
, Q5W0K8, Q6NSC3, Q8IXT6, Q9H5N8, Q9Y2I5, Q9Y451
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: October 1, 2000
Last modified: November 2, 2016
This is version 138 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 13
    Human chromosome 13: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.