Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative zinc finger protein 355P

Gene

ZNF355P

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein uncertaini

Functioni

May be involved in transcriptional regulation.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri72 – 9423C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri100 – 12223C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri128 – 15023C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri156 – 17823C2H2-type 4; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri184 – 20623C2H2-type 5; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri212 – 23423C2H2-type 6; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri263 – 28523C2H2-type 7; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri291 – 31323C2H2-type 8PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri335 – 35723C2H2-type 9PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri363 – 38523C2H2-type 10; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri391 – 41323C2H2-type 11PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Putative zinc finger protein 355P
Alternative name(s):
Zinc finger protein ZnFP01
Gene namesi
Name:ZNF355P
Synonyms:ZNF834
ORF Names:PRED65
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:17218. ZNF355P.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Polymorphism and mutation databases

DMDMi187671925.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 428428Putative zinc finger protein 355PPRO_0000332124Add
BLAST

Proteomic databases

PRIDEiQ9NSJ1.

PTM databases

PhosphoSiteiQ9NSJ1.

Structurei

3D structure databases

ProteinModelPortaliQ9NSJ1.
SMRiQ9NSJ1. Positions 69-428.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 6464KRABPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 11 C2H2-type zinc fingers.PROSITE-ProRule annotation
Contains 1 KRAB domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri72 – 9423C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri100 – 12223C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri128 – 15023C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri156 – 17823C2H2-type 4; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri184 – 20623C2H2-type 5; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri212 – 23423C2H2-type 6; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri263 – 28523C2H2-type 7; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri291 – 31323C2H2-type 8PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri335 – 35723C2H2-type 9PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri363 – 38523C2H2-type 10; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri391 – 41323C2H2-type 11PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

HOVERGENiHBG018163.
InParanoidiQ9NSJ1.
PhylomeDBiQ9NSJ1.

Family and domain databases

Gene3Di3.30.160.60. 14 hits.
InterProiIPR001909. KRAB.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 3 hits.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 11 hits.
[Graphical view]
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 6 hits.
PS50157. ZINC_FINGER_C2H2_2. 11 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9NSJ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRDEVAEKEK ADINVTLVFQ GYENTPIMVC VDGIVFSKPD LVTCLEQRKK
60 70 80 90 100
PWSMKHPGLT QHNIVHTGDK PYKCKDCGKI FKWSSNLTIH QRIHSGEKPY
110 120 130 140 150
KCEECGKAFK QSSKLNEHMR AHTGEKFYKC EECGKAFKHP SGLTLHKRIH
160 170 180 190 200
TGENPYKFEE CDKAFYWVLS FTKHMIIHRG EKPYKYQECG KAFKWSSNLT
210 220 230 240 250
IHKRIHTGEK PCKCEECGKA CKQSLGLTIQ KRIHTEEKPY KCEECGSSNL
260 270 280 290 300
TIYKKIHAGE KPYNCEKCGK AFYCSSNLIQ NNIVHAEEKH YKCQECGKAF
310 320 330 340 350
KKSLDLNVHK IIHSGEKPYR YEECGKITHS GEESYKCEEC GKGFYCSSSL
360 370 380 390 400
TKHMIVHTEE KLYKCEECGK AFKWSSELTI HQRIRTEEKP YKCEECVRVF
410 420
KHSSKLNEHK RNHTGEKPYK CEACGKAF
Length:428
Mass (Da):49,689
Last modified:April 29, 2008 - v2
Checksum:iD30694E8CB6B36E6
GO

Sequence cautioni

The sequence CAB90395.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL163202 Genomic DNA. Translation: CAB90395.1. Sequence problems.
PIRiA42075.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL163202 Genomic DNA. Translation: CAB90395.1. Sequence problems.
PIRiA42075.

3D structure databases

ProteinModelPortaliQ9NSJ1.
SMRiQ9NSJ1. Positions 69-428.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSiteiQ9NSJ1.

Polymorphism and mutation databases

DMDMi187671925.

Proteomic databases

PRIDEiQ9NSJ1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

GeneCardsiZNF355P.
HGNCiHGNC:17218. ZNF355P.
neXtProtiNX_Q9NSJ1.
GenAtlasiSearch...

Phylogenomic databases

HOVERGENiHBG018163.
InParanoidiQ9NSJ1.
PhylomeDBiQ9NSJ1.

Family and domain databases

Gene3Di3.30.160.60. 14 hits.
InterProiIPR001909. KRAB.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 3 hits.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 11 hits.
[Graphical view]
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 6 hits.
PS50157. ZINC_FINGER_C2H2_2. 11 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of human chromosome 21."
    Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T., Park H.-S., Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y., Soeda E., Ohki M., Takagi T., Sakaki Y., Taudien S., Blechschmidt K., Polley A.
    , Menzel U., Delabar J., Kumpf K., Lehmann R., Patterson D., Reichwald K., Rump A., Schillhabel M., Schudy A., Zimmermann W., Rosenthal A., Kudoh J., Shibuya K., Kawasaki K., Asakawa S., Shintani A., Sasaki T., Nagamine K., Mitsuyama S., Antonarakis S.E., Minoshima S., Shimizu N., Nordsiek G., Hornischer K., Brandt P., Scharfe M., Schoen O., Desario A., Reichelt J., Kauer G., Bloecker H., Ramser J., Beck A., Klages S., Hennig S., Riesselmann L., Dagand E., Wehrmeyer S., Borzym K., Gardiner K., Nizetic D., Francis F., Lehrach H., Reinhardt R., Yaspo M.-L.
    Nature 405:311-319(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "High-resolution localization of 69 potential human zinc finger protein genes: a number are clustered."
    Hoovers J.M.N., Mannens M., John R., Bliek J., van Heyningen V., Porteous D.J., Leschot N.J., Westerveld A., Little P.F.R.
    Genomics 12:254-263(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 58-83.

Entry informationi

Entry nameiZ355P_HUMAN
AccessioniPrimary (citable) accession number: Q9NSJ1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: April 29, 2008
Last modified: February 17, 2016
This is version 101 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 21
    Human chromosome 21: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.