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Q9NRW8

- Q9NRW8_HUMAN

UniProt

Q9NRW8 - Q9NRW8_HUMAN

Protein
Submitted name:

Neurofibromatosis type 2

Gene

NF2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
  1. Functioni

    GO - Biological processi

    1. cell-cell junction organization Source: Ensembl
    2. ectoderm development Source: Ensembl
    3. lens fiber cell differentiation Source: Ensembl
    4. mesoderm formation Source: Ensembl
    5. negative regulation of cell proliferation Source: Ensembl
    6. negative regulation of MAPK cascade Source: Ensembl
    7. negative regulation of protein kinase activity Source: Ensembl
    8. odontogenesis of dentin-containing tooth Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Neurofibromatosis type 2Imported
    Gene namesi
    Name:NF2Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. adherens junction Source: Ensembl
    2. cleavage furrow Source: Ensembl
    3. cortical actin cytoskeleton Source: Ensembl
    4. filopodium Source: Ensembl
    5. lamellipodium Source: Ensembl
    6. nucleus Source: Ensembl
    7. ruffle Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ9NRW8.
    BgeeiQ9NRW8.

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000007113.

    Sequencei

    Sequence statusi: Fragment.

    Q9NRW8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAGAIASRMS FSSLKRKQPK TFTVRIVTMD AEMEFNCE                38
    Length:38
    Mass (Da):4,313
    Last modified:October 1, 2000 - v1
    Checksum:iBA94460A25B8EE33
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei38 – 381Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF165426 Genomic DNA. Translation: AAF80764.1.
    UniGeneiHs.187898.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF165426 Genomic DNA. Translation: AAF80764.1 .
    UniGenei Hs.187898.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOGENOMi HOG000007113.

    Gene expression databases

    ArrayExpressi Q9NRW8.
    Bgeei Q9NRW8.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Identification of the cis-acting region in the NF2 gene promoter as a potential target for mutation and methylation-dependent silencing in schwannoma."
      Kino T., Takeshima H., Nakao M., Nishi T., Yamamoto K., Kimura T., Saito Y., Kochi M., Kuratsu J., Saya H., Ushio Y.
      Genes Cells 6:441-454(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ9NRW8_HUMAN
    AccessioniPrimary (citable) accession number: Q9NRW8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2000
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.