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Q9NRR5

- UBQL4_HUMAN

UniProt

Q9NRR5 - UBQL4_HUMAN

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Protein

Ubiquilin-4

Gene
UBQLN4, C1orf6, CIP75, UBIN
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Plays a role in the regulation of proteasomal protein degradation. Depending on the case, may promote or inhibit proteasomal protein degradation.1 Publication

GO - Molecular functioni

  1. identical protein binding Source: IntAct
  2. polyubiquitin binding Source: UniProtKB
  3. protein binding Source: UniProtKB

GO - Biological processi

  1. regulation of proteasomal ubiquitin-dependent protein catabolic process Source: UniProtKB
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquilin-4
Alternative name(s):
Ataxin-1 interacting ubiquitin-like protein
Short name:
A1Up
Ataxin-1 ubiquitin-like-interacting protein A1U
Connexin43-interacting protein of 75 kDa
Short name:
CIP75
Gene namesi
Name:UBQLN4
Synonyms:C1orf6, CIP75, UBIN
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 1

Organism-specific databases

HGNCiHGNC:1237. UBQLN4.

Subcellular locationi

Nucleus. Cytoplasm. Endoplasmic reticulum Inferred. Cytoplasmperinuclear region By similarity
Note: Colocalizes with the proteasome, both in nucleus and cytoplasm. May associate with the endoplasmic reticulum.2 Publications

GO - Cellular componenti

  1. centrosome Source: HPA
  2. cytoplasm Source: UniProtKB
  3. cytosol Source: UniProtKB
  4. endoplasmic reticulum membrane Source: UniProtKB
  5. intracellular membrane-bounded organelle Source: HPA
  6. nucleus Source: UniProtKB
  7. perinuclear region of cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Endoplasmic reticulum, Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25619.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 601601Ubiquilin-4PRO_0000211015Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei98 – 981Phosphoserine1 Publication

Post-translational modificationi

Ubiquitinated; this does not lead to proteasomal degradation. May undergo both 'Lys-48'- and 'Lys-63'-linked polyubiquitination.1 Publication

Keywords - PTMi

Phosphoprotein, Ubl conjugation

Proteomic databases

MaxQBiQ9NRR5.
PaxDbiQ9NRR5.
PRIDEiQ9NRR5.

PTM databases

PhosphoSiteiQ9NRR5.

Expressioni

Tissue specificityi

Highly expressed in pancreas, kidney, skeletal muscle, heart and throughout the brain, and at lower levels in placenta, lung and liver.1 Publication

Gene expression databases

BgeeiQ9NRR5.
CleanExiHS_UBQLN4.
GenevestigatoriQ9NRR5.

Organism-specific databases

HPAiHPA027920.

Interactioni

Subunit structurei

Binds signal sequences of proteins that are targeted to the endoplasmic reticulum. Interacts (via UBA domain) with GJA1 (not ubiquitinated) and with ubiquitin; both compete for the same binding site By similarity. Homodimer. Interacts (via UBA domain) with ubiquitin and with polyubiquitin chains. Interacts (via ubiquitin-like domain) with PSMD4, a regulatory subunit of the 26S proteasome. Interacts with ATXN1/SCA1. Interaction with ATXN1 inhibits polyubiquitination of UBQLN4 and interferes with PSMD4 binding.2 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
itself3EBI-711226,EBI-711226
ATXN1P542536EBI-711226,EBI-930964
FKBP2P268852EBI-711226,EBI-719873
MAP1LC3AQ9H4923EBI-711226,EBI-720768
MLLT6P551982EBI-711226,EBI-740216
PDLIM7Q9NR122EBI-711226,EBI-350517
RAI2Q9Y5P33EBI-711226,EBI-746228
TRIM32Q130493EBI-711226,EBI-742790
UBQLN1Q9UMX08EBI-711226,EBI-741480
ZNF205O952012EBI-711226,EBI-747343

Protein-protein interaction databases

BioGridi121223. 179 interactions.
IntActiQ9NRR5. 151 interactions.
MINTiMINT-1373057.
STRINGi9606.ENSP00000357292.

Structurei

3D structure databases

ProteinModelPortaliQ9NRR5.
SMRiQ9NRR5. Positions 13-83, 555-601.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini13 – 8775Ubiquitin-likeAdd
BLAST
Domaini553 – 59846UBAAdd
BLAST

Sequence similaritiesi

Contains 1 UBA domain.

Phylogenomic databases

eggNOGiCOG5272.
HOVERGENiHBG064537.
InParanoidiQ9NRR5.
KOiK04523.
OMAiFGMSRTT.
OrthoDBiEOG7HF1J8.
PhylomeDBiQ9NRR5.
TreeFamiTF314412.

Family and domain databases

InterProiIPR006636. STI1_HS-bd.
IPR009060. UBA-like.
IPR015940. UBA/transl_elong_EF1B_N_euk.
IPR000449. UBA/Ts_N.
IPR015496. Ubiquilin.
IPR000626. Ubiquitin-like.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PANTHERiPTHR10677. PTHR10677. 1 hit.
PfamiPF00627. UBA. 1 hit.
PF00240. ubiquitin. 1 hit.
[Graphical view]
SMARTiSM00727. STI1. 4 hits.
SM00165. UBA. 1 hit.
SM00213. UBQ. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50030. UBA. 1 hit.
PS50053. UBIQUITIN_2. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9NRR5-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MAEPSGAETR PPIRVTVKTP KDKEEIVICD RASVKEFKEE ISRRFKAQQD    50
QLVLIFAGKI LKDGDTLNQH GIKDGLTVHL VIKTPQKAQD PAAATASSPS 100
TPDPASAPST TPASPATPAQ PSTSGSASSD AGSGSRRSSG GGPSPGAGEG 150
SPSATASILS GFGGILGLGS LGLGSANFME LQQQMQRQLM SNPEMLSQIM 200
ENPLVQDMMS NPDLMRHMIM ANPQMQQLME RNPEISHMLN NPELMRQTME 250
LARNPAMMQE MMRNQDRALS NLESIPGGYN ALRRMYTDIQ EPMFSAAREQ 300
FGNNPFSSLA GNSDSSSSQP LRTENREPLP NPWSPSPPTS QAPGSGGEGT 350
GGSGTSQVHP TVSNPFGINA ASLGSGMFNS PEMQALLQQI SENPQLMQNV 400
ISAPYMRSMM QTLAQNPDFA AQMMVNVPLF AGNPQLQEQL RLQLPVFLQQ 450
MQNPESLSIL TNPRAMQALL QIQQGLQTLQ TEAPGLVPSL GSFGISRTPA 500
PSAGSNAGST PEAPTSSPAT PATSSPTGAS SAQQQLMQQM IQLLAGSGNS 550
QVQTPEVRFQ QQLEQLNSMG FINREANLQA LIATGGDINA AIERLLGSQL 600
S 601
Length:601
Mass (Da):63,853
Last modified:March 15, 2004 - v2
Checksum:iE57B9FFEF90793FE
GO
Isoform 2 (identifier: Q9NRR5-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     93-226: AATASSPSTP...HMIMANPQMQ → PPAAPSLPAA...AAQLHGLHQS
     227-601: Missing.

Note: No experimental confirmation available.

Show »
Length:226
Mass (Da):24,527
Checksum:i69101551F1551A93
GO

Sequence cautioni

The sequence AAF19084.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
The sequence AAH06410.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti495 – 4951I → M.2 Publications
Corresponds to variant rs2297792 [ dbSNP | Ensembl ].
VAR_052685

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei93 – 226134AATAS…NPQMQ → PPAAPSLPAADAEPRVTLHP YQSPSHAGIAADPAGTTDLA DRGPWAGTQPWLLWDIPDPS TLSRQQRRVYARGPHFLTSH ASHIFSNRGFQRPAATHAAD DPAFGWKWKLTGADARSEIS AAAGAAQLHGLHQS in isoform 2. VSP_041187Add
BLAST
Alternative sequencei227 – 601375Missing in isoform 2. VSP_041188Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti188 – 1892QL → HV in AAF80171. 1 Publication
Sequence conflicti298 – 2981R → Q in AAF80171. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF188240 mRNA. Translation: AAF80171.1.
AK098368 mRNA. No translation available.
AK314413 mRNA. Translation: BAG37034.1.
AL355388 Genomic DNA. Translation: CAH72633.1.
AL355388 Genomic DNA. Translation: CAH72634.1.
BC006410 mRNA. Translation: AAH06410.1. Different initiation.
BC018403 mRNA. Translation: AAH18403.1.
BC063841 mRNA. Translation: AAH63841.1.
AF113544 mRNA. Translation: AAF19084.1. Different initiation.
CCDSiCCDS1127.1. [Q9NRR5-1]
RefSeqiNP_064516.2. NM_020131.3. [Q9NRR5-1]
UniGeneiHs.283739.

Genome annotation databases

EnsembliENST00000368309; ENSP00000357292; ENSG00000160803. [Q9NRR5-1]
GeneIDi56893.
KEGGihsa:56893.
UCSCiuc001fna.3. human. [Q9NRR5-1]

Polymorphism databases

DMDMi45476982.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF188240 mRNA. Translation: AAF80171.1 .
AK098368 mRNA. No translation available.
AK314413 mRNA. Translation: BAG37034.1 .
AL355388 Genomic DNA. Translation: CAH72633.1 .
AL355388 Genomic DNA. Translation: CAH72634.1 .
BC006410 mRNA. Translation: AAH06410.1 . Different initiation.
BC018403 mRNA. Translation: AAH18403.1 .
BC063841 mRNA. Translation: AAH63841.1 .
AF113544 mRNA. Translation: AAF19084.1 . Different initiation.
CCDSi CCDS1127.1. [Q9NRR5-1 ]
RefSeqi NP_064516.2. NM_020131.3. [Q9NRR5-1 ]
UniGenei Hs.283739.

3D structure databases

ProteinModelPortali Q9NRR5.
SMRi Q9NRR5. Positions 13-83, 555-601.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 121223. 179 interactions.
IntActi Q9NRR5. 151 interactions.
MINTi MINT-1373057.
STRINGi 9606.ENSP00000357292.

PTM databases

PhosphoSitei Q9NRR5.

Polymorphism databases

DMDMi 45476982.

Proteomic databases

MaxQBi Q9NRR5.
PaxDbi Q9NRR5.
PRIDEi Q9NRR5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000368309 ; ENSP00000357292 ; ENSG00000160803 . [Q9NRR5-1 ]
GeneIDi 56893.
KEGGi hsa:56893.
UCSCi uc001fna.3. human. [Q9NRR5-1 ]

Organism-specific databases

CTDi 56893.
GeneCardsi GC01M156005.
HGNCi HGNC:1237. UBQLN4.
HPAi HPA027920.
MIMi 605440. gene.
neXtProti NX_Q9NRR5.
PharmGKBi PA25619.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG5272.
HOVERGENi HBG064537.
InParanoidi Q9NRR5.
KOi K04523.
OMAi FGMSRTT.
OrthoDBi EOG7HF1J8.
PhylomeDBi Q9NRR5.
TreeFami TF314412.

Miscellaneous databases

ChiTaRSi UBQLN4. human.
GenomeRNAii 56893.
NextBioi 62315.
PROi Q9NRR5.
SOURCEi Search...

Gene expression databases

Bgeei Q9NRR5.
CleanExi HS_UBQLN4.
Genevestigatori Q9NRR5.

Family and domain databases

InterProi IPR006636. STI1_HS-bd.
IPR009060. UBA-like.
IPR015940. UBA/transl_elong_EF1B_N_euk.
IPR000449. UBA/Ts_N.
IPR015496. Ubiquilin.
IPR000626. Ubiquitin-like.
IPR029071. Ubiquitin-rel_dom.
[Graphical view ]
PANTHERi PTHR10677. PTHR10677. 1 hit.
Pfami PF00627. UBA. 1 hit.
PF00240. ubiquitin. 1 hit.
[Graphical view ]
SMARTi SM00727. STI1. 4 hits.
SM00165. UBA. 1 hit.
SM00213. UBQ. 1 hit.
[Graphical view ]
SUPFAMi SSF46934. SSF46934. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEi PS50030. UBA. 1 hit.
PS50053. UBIQUITIN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein."
    Davidson J.D., Riley B., Burright E.N., Duvick L.A., Zoghbi H.Y., Orr H.T.
    Hum. Mol. Genet. 9:2305-2312(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), SUBCELLULAR LOCATION, INTERACTION WITH ATXN1/SCA1, TISSUE SPECIFICITY.
    Tissue: Brain.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANT MET-495.
    Tissue: Brain.
  3. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Brain, Colon and PNS.
  5. "Identification of two paralogous regions mapping to the short and long arms of human chromosome 2 comprising LIS1 pseudogenes."
    Fogli A., Giglio S., Lo Nigro C., Zollo M., Viggiano L., Rocchi M., Archidiacono N., Zuffardi O., Carrozzo R.
    Cytogenet. Cell Genet. 86:225-232(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 161-601 (ISOFORM 1), VARIANT MET-495.
  6. "The effects of the polyglutamine repeat protein ataxin-1 on the UbL-UBA protein A1Up."
    Riley B.E., Xu Y., Zoghbi H.Y., Orr H.T.
    J. Biol. Chem. 279:42290-42301(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH UBIQUITIN; ATXN1 AND PSMD4, SUBUNIT, SUBCELLULAR LOCATION, UBIQUITINATION.
  7. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic kidney.
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-98, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  9. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiUBQL4_HUMAN
AccessioniPrimary (citable) accession number: Q9NRR5
Secondary accession number(s): A6ND44
, B2RAY7, Q5VYA0, Q5VYA1, Q9BR98, Q9UHX4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: March 15, 2004
Last modified: July 9, 2014
This is version 122 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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