Reviewed, UniProtKB/Swiss-Prot Q9NRP4 (ACN9_HUMAN)

Names and origin

Protein names

Recommended name:
    Protein ACN9 homolog, mitochondrial

Gene names

Name:	ACN9
ORF Names:	DC11

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	125 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location	Mitochondrion Potential.
Sequence similarities	Belongs to the ACN9 family.

Ontologies

Keywords
Cellular component	Mitochondrion
Domain	Transit peptide
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from sequence or structural similarity. Source: HGNC
Cellular component	mitochondrial intermembrane space Inferred from sequence or structural similarity. Source: HGNC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 30	30	Mitochondrion Potential
	Chain	31 – 125	95	Protein ACN9 homolog, mitochondrial		PRO_0000042653

Sequences

	Sequence		Length	Mass (Da)
	Q9NRP4-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 8C6897D7815966FA	FASTA	125	14,652
	10 20 30 40 50 60 MPGRHVSRVR ALYKRVLQLH RVLPPDLKSL GDQYVKDEFR RHKTVGSDEA QRFLQEWEVY 70 80 90 100 110 120 ATALLQQANE NRQNSTGKAC FGTFLPEEKL NDFRDEQIGQ LQELMQEATK PNRQFSISES MKPKF

References

[1]	"Novel genes expressed in human dendritic cell." Gu J., Huang Q., Shi J., Xu S., Han Z., Fu G., Chen Z. Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Dendritic cell.
[2]	"The DNA sequence of human chromosome 7." Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L. , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K. Nature 424:157-164(2003) [PubMed: 12853948] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Bone marrow and Liver.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF201933 mRNA. Translation: AAF86869.1. AC073421 Genomic DNA. No translation available. AC073900 Genomic DNA. Translation: AAS07570.1. BC020621 mRNA. Translation: AAH20621.1. BC022858 mRNA. Translation: AAH22858.1.
IPI	IPI00743454.
RefSeq	NP_064571.1.
UniGene	Hs.592269
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q9NRP4.
Proteomic databases
PRIDE	Q9NRP4.
Genome annotation databases
Ensembl	ENST00000432641; ENSP00000414066; ENSG00000196636; Homo sapiens. [Genome view]
GeneID	57001.
KEGG	hsa:57001.
UCSC	uc003uoo.2. human.
Organism-specific databases
CTD	57001.
GeneCards	GC07P096583.
HGNC	HGNC:21752. ACN9.
PharmGKB	PA134976380.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HBG716384.
HOVERGEN	Q9NRP4.
InParanoid	Q9NRP4.
OMA	FLQEWEA.
OrthoDB	EOG9GMXGV.
Gene expression databases
ArrayExpress	Q9NRP4.
Bgee	Q9NRP4.
CleanEx	HS_ACN9.
Genevestigator	Q9NRP4.
Family and domain databases
InterPro	IPR008381. ACN9. [Graphical view]
PANTHER	PTHR13137. ACN9. 1 hit.
Pfam	PF05882. ACN9. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	62731.

Entry information

Entry name

ACN9_HUMAN

Accession

Primary (citable) accession number: Q9NRP4
Secondary accession number(s): Q75MD6

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 25, 2005
Last sequence update:	October 1, 2000
Last modified:	December 15, 2009
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.