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Q9NRC6

- SPTN5_HUMAN

UniProt

Q9NRC6 - SPTN5_HUMAN

Protein

Spectrin beta chain, non-erythrocytic 5

Gene

SPTBN5

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 119 (01 Oct 2014)
      Sequence version 2 (01 Oct 2014)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. actin binding Source: UniProtKB
    2. dynactin binding Source: MGI
    3. dynein intermediate chain binding Source: MGI
    4. kinesin binding Source: MGI
    5. myosin tail binding Source: MGI
    6. protein self-association Source: MGI
    7. spectrin binding Source: MGI

    GO - Biological processi

    1. actin cytoskeleton organization Source: UniProtKB
    2. actin filament capping Source: UniProtKB-KW
    3. axon guidance Source: Reactome
    4. Golgi organization Source: MGI
    5. lysosomal transport Source: MGI
    6. protein homooligomerization Source: MGI

    Keywords - Molecular functioni

    Actin capping

    Keywords - Ligandi

    Actin-binding

    Enzyme and pathway databases

    ReactomeiREACT_18334. NCAM signaling for neurite out-growth.
    REACT_22266. Interaction between L1 and Ankyrins.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Spectrin beta chain, non-erythrocytic 5
    Alternative name(s):
    Beta-V spectrin
    Gene namesi
    Name:SPTBN5
    Synonyms:BSPECV, HUBSPECV, HUSPECV
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 15

    Organism-specific databases

    HGNCiHGNC:15680. SPTBN5.

    Subcellular locationi

    Cytoplasmcytoskeleton
    Note: Detected prominently in the outer segments of photoreceptor rods and cones and in the basolateral membrane and cytosol of gastric epithelial cells.

    GO - Cellular componenti

    1. cytoplasm Source: MGI
    2. cytosol Source: Reactome
    3. extracellular vesicular exosome Source: UniProt
    4. membrane Source: UniProtKB
    5. photoreceptor connecting cilium Source: MGI
    6. photoreceptor disc membrane Source: MGI
    7. spectrin Source: UniProtKB

    Keywords - Cellular componenti

    Cytoplasm, Cytoskeleton

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA38020.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 36743674Spectrin beta chain, non-erythrocytic 5PRO_0000073466Add
    BLAST

    Proteomic databases

    PaxDbiQ9NRC6.
    PRIDEiQ9NRC6.

    PTM databases

    PhosphoSiteiQ9NRC6.

    Expressioni

    Tissue specificityi

    Expressed at very low levels in many tissues, with strongest expression in cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder, and heart.

    Gene expression databases

    BgeeiQ9NRC6.
    CleanExiHS_SPTBN4.
    HS_SPTBN5.
    GenevestigatoriQ9NRC6.

    Interactioni

    Subunit structurei

    Probably associates with an alpha chain. Interacts (via C-terminus) with TRPC4.1 Publication

    Protein-protein interaction databases

    STRINGi9606.ENSP00000317790.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9NRC6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini1 – 279279Actin-bindingAdd
    BLAST
    Domaini54 – 159106CH 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini177 – 279103CH 2PROSITE-ProRule annotationAdd
    BLAST
    Repeati306 – 416111Spectrin 1Add
    BLAST
    Repeati426 – 531106Spectrin 2Add
    BLAST
    Repeati533 – 637105Spectrin 3Add
    BLAST
    Repeati639 – 743105Spectrin 4Add
    BLAST
    Repeati745 – 81066Spectrin 5Add
    BLAST
    Repeati867 – 89428Spectrin 6Add
    BLAST
    Repeati896 – 998103Spectrin 7Add
    BLAST
    Repeati1102 – 1206105Spectrin 8Add
    BLAST
    Repeati1208 – 1312105Spectrin 9Add
    BLAST
    Repeati1314 – 1417104Spectrin 10Add
    BLAST
    Repeati1419 – 148870Spectrin 11Add
    BLAST
    Repeati1520 – 1624105Spectrin 12Add
    BLAST
    Repeati1626 – 1728103Spectrin 13Add
    BLAST
    Repeati1730 – 1835106Spectrin 14Add
    BLAST
    Repeati1837 – 1941105Spectrin 15Add
    BLAST
    Repeati1943 – 2047105Spectrin 16Add
    BLAST
    Repeati2049 – 214799Spectrin 17Add
    BLAST
    Repeati2149 – 2253105Spectrin 18Add
    BLAST
    Repeati2255 – 230147Spectrin 19Add
    BLAST
    Repeati2314 – 236249Spectrin 20Add
    BLAST
    Repeati2364 – 2468105Spectrin 21Add
    BLAST
    Repeati2470 – 2574105Spectrin 22Add
    BLAST
    Repeati2576 – 2680105Spectrin 23Add
    BLAST
    Repeati2682 – 2785104Spectrin 24Add
    BLAST
    Repeati2787 – 2891105Spectrin 25Add
    BLAST
    Repeati2893 – 2997105Spectrin 26Add
    BLAST
    Repeati2999 – 3103105Spectrin 27Add
    BLAST
    Repeati3105 – 3210106Spectrin 28Add
    BLAST
    Repeati3212 – 3312101Spectrin 29Add
    BLAST
    Repeati3314 – 3418105Spectrin 30Add
    BLAST
    Repeati3420 – 348263Spectrin 31Add
    BLAST
    Domaini3533 – 3641109PHPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the spectrin family.Curated
    Contains 2 CH (calponin-homology) domains.PROSITE-ProRule annotation
    Contains 1 PH domain.PROSITE-ProRule annotation
    Contains 31 spectrin repeats.Curated

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiCOG5069.
    HOGENOMiHOG000168577.
    InParanoidiQ9NRC6.
    KOiK06115.
    OrthoDBiEOG7KM5RV.
    PhylomeDBiQ9NRC6.
    TreeFamiTF313446.

    Family and domain databases

    Gene3Di1.10.418.10. 2 hits.
    2.30.29.30. 1 hit.
    InterProiIPR001589. Actinin_actin-bd_CS.
    IPR001715. CH-domain.
    IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    IPR018159. Spectrin/alpha-actinin.
    IPR002017. Spectrin_repeat.
    [Graphical view]
    PfamiPF00307. CH. 2 hits.
    PF00435. Spectrin. 27 hits.
    [Graphical view]
    SMARTiSM00033. CH. 2 hits.
    SM00233. PH. 1 hit.
    SM00150. SPEC. 29 hits.
    [Graphical view]
    SUPFAMiSSF47576. SSF47576. 1 hit.
    PROSITEiPS00019. ACTININ_1. 1 hit.
    PS00020. ACTININ_2. 1 hit.
    PS50021. CH. 2 hits.
    PS50003. PH_DOMAIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9NRC6-1 [UniParc]FASTAAdd to Basket

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    MAGQPHSPRE LLGAAGHRSR RPSTELRVPP SPSLTMDSQY ETGHIRKLQA     50
    RHMQMQEKTF TKWINNVFQC GQAGIKIRNL YTELADGIHL LRLLELISGE 100
    ALPPPSRGRL RVHFLENSSR ALAFLRAKVP VPLIGPENIV DGDQTLILGL 150
    IWVIILRFQI SHISLDKEEF GASAALLSTK EALLVWCQRK TASYTNVNIT 200
    DFSRSWSDGL GFNALIHAHR PDLLDYGSLR PDRPLHNLAF AFLVAEQELG 250
    IAQLLDPEDV AAAQPDERSI MTYVSLYYHY CSRLHQGQTV QRRLTKILLQ 300
    LQETELLQTQ YEQLVADLLR WIAEKQMQLE ARDFPDSLPA MRQLLAAFTI 350
    FRTQEKPPRL QQRGAAEALL FRLQTALQAQ NRRPFLPHEG LGLAELSQCW 400
    AGLEWAEAAR SQALQQRLLQ LQRLETLARR FQHKAALRES FLKDAEQVLD 450
    QARAPPASLA TVEAAVQRLG MLEAGILPQE GRFQALAEIA DILRQEQYHS 500
    WADVARRQEE VTVRWQRLLQ HLQGQRKQVA DMQAVLSLLQ EVEAASHQLE 550
    ELQEPARSTA CGQQLAEVVE LLQRHDLLEA QVSAHGAHVS HLAQQTAELD 600
    SSLGTSVEVL QAKARTLAQL QQSLVALVRA RRALLEQTLQ RAEFLRNCEE 650
    EEAWLKECGQ RVGNAALGRD LSQIAGALQK HKALEAEVHR HQAVCVDLVR 700
    RGRDLSARRP PTQPDPGERA EAVQGGWQLL QTRVVGRGAR LQTALLVLQY 750
    FADAAEAASW LRERRSSLER ASCGQDQAAA ETLLRRHVRL ERVLRAFAAE 800
    LRRLEEQGRA ASARASLFTV NSALSPPGES LRNPGPWSEA SCHPGPGDAW 850
    KMALPAEPDP DFDPNTILQT QDHLSQDYES LRALAQLRRA RLEEAMALFG 900
    FCSSCGELQL WLEKQTVLLQ RVQPQADTLE VMQLKYENFL TALAVGKGLW 950
    AEVSSSAEQL RQRYPGNSTQ IQRQQEELSQ RWGQLEALKR EKAVQLAHSV 1000
    EVCSFLQECG PTQVQLRDVL LQLEALQPGS SEDTCHALQL AQKKTLVLER 1050
    RVHFLQSVVV KVEEPGYAES QPLQGQVETL QGLLKQVQEQ VAQRARRQAE 1100
    TQARQSFLQE SQQLLLWAES VQAQLRSKEV SVDVASAQRL LREHQDLLEE 1150
    IHLWQERLQQ LDAQSQPMAA LDCPDSQEVP NTLRVLGQQG QELKVLWEQR 1200
    QQWLQEGLEL QKFGREVDGF TATCANHQAW LHLDNLGEDV REALSLLQQH 1250
    REFGRLLSTL GPRAEALRAH GEKLVQSQHP AAHTVREQLQ SIQAQWTRLQ 1300
    GRSEQRRRQL LASLQLQEWK QDVAELMQWM EEKGLMAAHE PSGARRNILQ 1350
    TLKRHEAAES ELLATRRHVE ALQQVGRELL SRRPCGQEDI QTRLQGLRSK 1400
    WEALNRKMTE RGDELQQAGQ QEQLLRQLQD AKEQLEQLEG ALQSSETGQD 1450
    LRSSQRLQKR HQQLESESRT LAAKMAALAS MAHGMAASPA ILEETQKHLR 1500
    RLELLQGHLA IRGLQLQASV ELHQFCHLSN MELSWVAEHM PHGSPTSYTE 1550
    CLNGAQSLHR KHKELQVEVK AHQGQVQRVL SSGRSLAASG HPQAQHIVEQ 1600
    CQELEGHWAE LERACEARAQ CLQQAVTFQQ YFLDVSELEG WVEEKRPLVS 1650
    SRDYGRDEAA TLRLINKHQA LQEELAIYWS SMEELDQTAQ TLTGPEVPEQ 1700
    QRVVQERLRE QLRALQELAA TRDRELEGTL RLHEFLREAE DLQGWLASQK 1750
    QAAKGGESLG EDPEHALHLC TKFAKFQHQV EMGSQRVAAC RLLAESLLER 1800
    GHSAGPMVRQ RQQDLQTAWS ELWELTQARG HALRDTETTL RVHRDLLEVL 1850
    TQVQEKATSL PNNVARDLCG LEAQLRSHQG LERELVGTER QLQELLETAG 1900
    RVQKLCPGPQ AHAVQQRQQA VTQAWAVLQR RMEQRRAQLE RARLLARFRT 1950
    AVRDYASWAA RVRQDLQVEE SSQEPSSGPL KLSAHQWLRA ELEAREKLWQ 2000
    QATQLGQQAL LAAGTPTKEV QEELRALQDQ RDQVYQTWAR KQERLQAEQQ 2050
    EQLFLRECGR LEEILAAQEV SLKTSALGSS VEEVEQLIRK HEVFLKVLTA 2100
    QDKKEAALRE RLKTLRRPRV RDRLPILLQR RMRVKELAES RGHALHASLL 2150
    MASFTQAATQ AEDWIQAWAQ QLKEPVPPGD LRDKLKPLLK HQAFEAEVQA 2200
    HEEVMTSVAK KGEALLAQSH PRAGEVSQRL QGLRKHWEDL RQAMALRGQE 2250
    LEDRRNFLEF LQRVDLAEAW IQEKEVKMNV GDLGQDLEHC LQLRRRLREF 2300
    RGNSAGDTVG DACIRSISDL SLQLKNRDPE EVKIICQRRS QLNNRWASFH 2350
    GNLLRYQQQL EGALEIHVLS RELDNVTKRI QEKEALIQAL DCGKDLESVQ 2400
    RLLRKHEELE REVHPIQAQV ESLEREVGRL CQRSPEAAHG LRHRQQEVAE 2450
    SWWQLRSRAQ KRREALDALH QAQKLQAMLQ ELLVSAQRLR AQMDTSPAPR 2500
    SPVEARRMLE EHQECKAELD SWTDSISLAR STGQQLLTAG HPFSSDIRQV 2550
    LAGLEQELSS LEGAWQEHQL QLQQALELQL FLSSVEKMER WLCSKEDSLA 2600
    SEGLWDPLAP MEPLLWKHKM LEWDLEVQAG KISALEATAR GLHQGGHPEA 2650
    QSALGRCQAM LLRKEALFRQ AGTRRHRLEE LRQLQAFLQD SQEVAAWLRE 2700
    KNLVALEEGL LDTAMLPAQL QKQQNFQAEL DASMHQQQEL QREGQRLLQG 2750
    GHPASEAIQE RLEELGALWG ELQDNSQKKV AKLQKACEAL RLRRSMEELE 2800
    NWLEPIEVEL RAPTVGQALP GVGELLGTQR ELEAAVDKKA RQAEALLGQA 2850
    QAFVREGHCL AQDVEEQARR LLQRFKSLRE PLQERRTALE ARSLLLKFFR 2900
    DADEEMAWVQ EKLPLAAAQD YGQSLSAVRH LQEQHQNLES EMSSHEALTR 2950
    VVLGTGYKLV QAGHFAAHEV AARVQQLEKA MAHLRAEAAR RRLLLQQAQE 3000
    AQQFLTELLE AGSWLAERGH VLDSEDMGHS AEATQALLRR LEATKRDLEA 3050
    FSPRIERLQQ TAALLESRKN PESPKVLAQL QAVREAHAEL LRRAEARGHG 3100
    LQEQLQLHQL ERETLLLDAW LTTKAATAES QDYGQDLEGV KVLEEKFDAF 3150
    RKEVQSLGQA KVYALRKLAG TLERGAPRRY PHIQAQRSRI EAAWERLDQA 3200
    IKARTENLAA AHEVHSFQQA AAELQGRMQE KTALMKGEDG GHSLSSVRTL 3250
    QQQHRRLERE LEAMEKEVAR LQTEACRLGQ LHPAAPGGLA KVQEAWATLQ 3300
    AKAQERGQWL AQAAQGHAFL GRCQELLAWA QERQELASSE ELAEDVAGAE 3350
    QLLGQHEELG QEIRECRLQA QDLRQEGQQL VDNSHFMSAE VTECLQELEG 3400
    RLQELEEAWA LRWQRCAESW GLQKLRQRLE QAEAWLACWE GLLLKPDYGH 3450
    SVSDVELLLH RHQDLEKLLA AQEEKFAQMQ KTEMEQELLL QPQELKPGRA 3500
    GSSLTSFQWR PSGHQGLGAQ LAETRDPQDA KGTPTMEGSL EFKQHLLPGG 3550
    RQPSSSSWDS CRGNLQGSSL SLFLDERMAA EKVASIALLD LTGARCERLR 3600
    GRHGRKHTFS LRLTSGAEIL FAAPSEEQAE SWWRALGSTA AQSLSPKLKA 3650
    KPVSSLNECT TKDARPGCLL RSDP 3674
    Length:3,674
    Mass (Da):416,750
    Last modified:October 1, 2014 - v2
    Checksum:i83D1F94ADE670E13
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti433 – 4331H → R in AAF65317. (PubMed:10764729)Curated
    Sequence conflicti1035 – 10351C → R in AAF65317. (PubMed:10764729)Curated
    Sequence conflicti1053 – 10531H → Y in AAF65317. (PubMed:10764729)Curated
    Sequence conflicti3564 – 35641N → T in AAF65317. (PubMed:10764729)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti1345 – 13451R → H.
    Corresponds to variant rs2290559 [ dbSNP | Ensembl ].
    VAR_022050
    Natural varianti1367 – 13671R → T.
    Corresponds to variant rs2290558 [ dbSNP | Ensembl ].
    VAR_024395
    Natural varianti2862 – 28621Q → R.
    Corresponds to variant rs1456235 [ dbSNP | Ensembl ].
    VAR_024396
    Natural varianti3275 – 32751A → G.
    Corresponds to variant rs1197660 [ dbSNP | Ensembl ].
    VAR_024397

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF233523 mRNA. Translation: AAF65317.1.
    AC020659 Genomic DNA. No translation available.
    CCDSiCCDS61599.1.
    RefSeqiNP_057726.4. NM_016642.3.
    UniGeneiHs.709819.

    Genome annotation databases

    EnsembliENST00000320955; ENSP00000317790; ENSG00000137877.
    GeneIDi51332.
    KEGGihsa:51332.
    UCSCiuc001zos.4. human.

    Polymorphism databases

    DMDMi17369320.

    Keywords - Coding sequence diversityi

    Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF233523 mRNA. Translation: AAF65317.1 .
    AC020659 Genomic DNA. No translation available.
    CCDSi CCDS61599.1.
    RefSeqi NP_057726.4. NM_016642.3.
    UniGenei Hs.709819.

    3D structure databases

    ProteinModelPortali Q9NRC6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9606.ENSP00000317790.

    PTM databases

    PhosphoSitei Q9NRC6.

    Polymorphism databases

    DMDMi 17369320.

    Proteomic databases

    PaxDbi Q9NRC6.
    PRIDEi Q9NRC6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000320955 ; ENSP00000317790 ; ENSG00000137877 .
    GeneIDi 51332.
    KEGGi hsa:51332.
    UCSCi uc001zos.4. human.

    Organism-specific databases

    CTDi 51332.
    GeneCardsi GC15M042140.
    H-InvDB HIX0012162.
    HGNCi HGNC:15680. SPTBN5.
    MIMi 605916. gene.
    neXtProti NX_Q9NRC6.
    PharmGKBi PA38020.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG5069.
    HOGENOMi HOG000168577.
    InParanoidi Q9NRC6.
    KOi K06115.
    OrthoDBi EOG7KM5RV.
    PhylomeDBi Q9NRC6.
    TreeFami TF313446.

    Enzyme and pathway databases

    Reactomei REACT_18334. NCAM signaling for neurite out-growth.
    REACT_22266. Interaction between L1 and Ankyrins.

    Miscellaneous databases

    GeneWikii SPTBN5.
    GenomeRNAii 51332.
    NextBioi 54747.
    PROi Q9NRC6.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q9NRC6.
    CleanExi HS_SPTBN4.
    HS_SPTBN5.
    Genevestigatori Q9NRC6.

    Family and domain databases

    Gene3Di 1.10.418.10. 2 hits.
    2.30.29.30. 1 hit.
    InterProi IPR001589. Actinin_actin-bd_CS.
    IPR001715. CH-domain.
    IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    IPR018159. Spectrin/alpha-actinin.
    IPR002017. Spectrin_repeat.
    [Graphical view ]
    Pfami PF00307. CH. 2 hits.
    PF00435. Spectrin. 27 hits.
    [Graphical view ]
    SMARTi SM00033. CH. 2 hits.
    SM00233. PH. 1 hit.
    SM00150. SPEC. 29 hits.
    [Graphical view ]
    SUPFAMi SSF47576. SSF47576. 1 hit.
    PROSITEi PS00019. ACTININ_1. 1 hit.
    PS00020. ACTININ_2. 1 hit.
    PS50021. CH. 2 hits.
    PS50003. PH_DOMAIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Identification and characterization of beta V spectrin, a mammalian ortholog of Drosophila beta H spectrin."
      Stabach P.R., Morrow J.S.
      J. Biol. Chem. 275:21385-21395(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Cerebellum, Retina and Spinal cord.
    2. "Analysis of the DNA sequence and duplication history of human chromosome 15."
      Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A.
      , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.
      Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. "The spectrin cytoskeleton influences the surface expression and activation of human transient receptor potential channel 4 channels."
      Odell A.F., Van Helden D.F., Scott J.L.
      J. Biol. Chem. 283:4395-4407(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH TRPC4.

    Entry informationi

    Entry nameiSPTN5_HUMAN
    AccessioniPrimary (citable) accession number: Q9NRC6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 16, 2001
    Last sequence update: October 1, 2014
    Last modified: October 1, 2014
    This is version 119 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 15
      Human chromosome 15: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3