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Protein
Submitted name:

G-protein coupled receptor EDG-7

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
G-protein coupled receptor EDG-7Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei30 – 53HelicalSequence analysisAdd BLAST24
Transmembranei65 – 88HelicalSequence analysisAdd BLAST24
Transmembranei108 – 125HelicalSequence analysisAdd BLAST18
Transmembranei145 – 167HelicalSequence analysisAdd BLAST23
Transmembranei187 – 207HelicalSequence analysisAdd BLAST21
Transmembranei240 – 261HelicalSequence analysisAdd BLAST22
Transmembranei277 – 295HelicalSequence analysisAdd BLAST19

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ9NRB8.
PeptideAtlasiQ9NRB8.
PRIDEiQ9NRB8.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000359643.

Structurei

3D structure databases

ProteinModelPortaliQ9NRB8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini47 – 293G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST247

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOGENOMiHOG000233501.
HOVERGENiHBG103071.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR004065. LPA_rcpt.
IPR005385. LPA_rcpt_EDG7.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR01560. EDG7RECEPTOR.
PR00237. GPCRRHODOPSN.
PR01527. LPARECEPTOR.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9NRB8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNECHYDKHM DFFYNRSNTD TVDDWTGTKL VIVLCVGTFF CLFIFFSNSL
60 70 80 90 100
VIAAVIKNRK FHFPFYYLLA NLAAADFFAG IAYVFLMFNT GPVSKTLTVN
110 120 130 140 150
RWFLRQGLLD SSLTASLTNL LVIAVERHMS IMRMRVHSNL TKKRVTLLIL
160 170 180 190 200
LVWAIAIFMG AVPTLGWNCL CNISACSSLA PIYSRSYLVF WTVSNLMAFL
210 220 230 240 250
IMVVVYLRIY VYVKRKTNVL SPHTSGSISR RRTPMKLMKT VMTVLGAFVV
260 270 280 290 300
CWTPGLVVLL LDGLNCTQCG VQHVKRWFLL LALLNSVMNP IIYSYKDEDM
310 320 330 340 350
YSTMKKMICC FSQERNLDRR PSRLPSTILS RSDTGSQYKE DSSSQGTVCN

KNSS
Length:354
Mass (Da):40,340
Last modified:October 1, 2000 - v1
Checksum:iA70ED5CFA6F7D706
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF236117 mRNA. Translation: AAF91291.1.
UniGeneiHs.527909.
Hs.674915.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF236117 mRNA. Translation: AAF91291.1.
UniGeneiHs.527909.
Hs.674915.

3D structure databases

ProteinModelPortaliQ9NRB8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000359643.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiQ9NRB8.
PeptideAtlasiQ9NRB8.
PRIDEiQ9NRB8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOGENOMiHOG000233501.
HOVERGENiHBG103071.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR004065. LPA_rcpt.
IPR005385. LPA_rcpt_EDG7.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR01560. EDG7RECEPTOR.
PR00237. GPCRRHODOPSN.
PR01527. LPARECEPTOR.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9NRB8_HUMAN
AccessioniPrimary (citable) accession number: Q9NRB8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: July 6, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.