SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9NR16

- C163B_HUMAN

UniProt

Q9NR16 - C163B_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Scavenger receptor cysteine-rich type 1 protein M160

Gene
CD163L1, CD163B, M160, UNQ6434/PRO23202
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. scavenger receptor activity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Scavenger receptor cysteine-rich type 1 protein M160
Alternative name(s):
CD163 antigen-like 1
CD_antigen: CD163b
Gene namesi
Name:CD163L1
Synonyms:CD163B, M160
ORF Names:UNQ6434/PRO23202
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 12

Organism-specific databases

HGNCiHGNC:30375. CD163L1.

Subcellular locationi

Isoform 3 : Secreted Inferred

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini41 – 13591319Extracellular Reviewed predictionAdd
BLAST
Transmembranei1360 – 138021Helical; Reviewed predictionAdd
BLAST
Topological domaini1381 – 145373Cytoplasmic Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
  2. integral component of membrane Source: UniProtKB-KW
  3. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane, Secreted

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142672145.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 40401 PublicationAdd
BLAST
Chaini41 – 14531413Scavenger receptor cysteine-rich type 1 protein M160PRO_0000045392Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi42 – 421N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi73 ↔ 137 By similarity
Glycosylationi78 – 781N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi86 ↔ 147 By similarity
Disulfide bondi117 ↔ 127 By similarity
Glycosylationi120 – 1201N-linked (GlcNAc...) Reviewed prediction
Glycosylationi161 – 1611N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi180 ↔ 244 By similarity
Disulfide bondi193 ↔ 254 By similarity
Disulfide bondi224 ↔ 234 By similarity
Disulfide bondi287 ↔ 351 By similarity
Disulfide bondi300 ↔ 361 By similarity
Disulfide bondi331 ↔ 341 By similarity
Glycosylationi334 – 3341N-linked (GlcNAc...) Reviewed prediction
Glycosylationi377 – 3771N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi394 ↔ 458 By similarity
Disulfide bondi407 ↔ 468 By similarity
Disulfide bondi438 ↔ 448 By similarity
Glycosylationi441 – 4411N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi501 ↔ 565 By similarity
Disulfide bondi514 ↔ 575 By similarity
Disulfide bondi545 ↔ 555 By similarity
Glycosylationi548 – 5481N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi608 ↔ 672 By similarity
Disulfide bondi621 ↔ 682 By similarity
Glycosylationi637 – 6371N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi652 ↔ 662 By similarity
Disulfide bondi715 ↔ 779 By similarity
Disulfide bondi728 ↔ 789 By similarity
Disulfide bondi759 ↔ 769 By similarity
Disulfide bondi820 ↔ 884 By similarity
Disulfide bondi833 ↔ 894 By similarity
Disulfide bondi864 ↔ 874 By similarity
Disulfide bondi925 ↔ 989 By similarity
Disulfide bondi938 ↔ 999 By similarity
Disulfide bondi969 ↔ 979 By similarity
Glycosylationi972 – 9721N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1013 – 10131N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi1061 ↔ 1125 By similarity
Disulfide bondi1074 ↔ 1135 By similarity
Glycosylationi1084 – 10841N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1104 – 11041N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi1105 ↔ 1115 By similarity
Glycosylationi1161 – 11611N-linked (GlcNAc...)1 Publication
Glycosylationi1171 – 11711N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi1181 ↔ 1242 By similarity
Disulfide bondi1212 ↔ 1222 By similarity
Disulfide bondi1271 ↔ 1335 By similarity
Disulfide bondi1284 ↔ 1345 By similarity
Disulfide bondi1315 ↔ 1325 By similarity
Glycosylationi1318 – 13181N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1354 – 13541N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ9NR16.
PRIDEiQ9NR16.

PTM databases

PhosphoSiteiQ9NR16.

Expressioni

Tissue specificityi

Isoform 1 is highly expressed in the spleen, lymph nodes, thymus, and fetal liver and weakly expressed in bone marrow and no expression was found in peripheral blood leukocytes. Isoform 1 expression is restricted to the monocyte and macrophage cell lines. Isoform 2 is only expressed in spleen.1 Publication

Gene expression databases

ArrayExpressiQ9NR16.
BgeeiQ9NR16.
CleanExiHS_CD163L1.
GenevestigatoriQ9NR16.

Organism-specific databases

HPAiHPA015663.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000315945.

Structurei

3D structure databases

ProteinModelPortaliQ9NR16.
SMRiQ9NR16. Positions 45-153, 155-260, 262-362, 366-474, 487-576, 583-683, 686-790, 796-898, 900-1000, 1031-1141, 1246-1349.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini48 – 148101SRCR 1Add
BLAST
Domaini155 – 255101SRCR 2Add
BLAST
Domaini262 – 362101SRCR 3Add
BLAST
Domaini369 – 469101SRCR 4Add
BLAST
Domaini476 – 576101SRCR 5Add
BLAST
Domaini583 – 683101SRCR 6Add
BLAST
Domaini690 – 790101SRCR 7Add
BLAST
Domaini795 – 895101SRCR 8Add
BLAST
Domaini900 – 1000101SRCR 9Add
BLAST
Domaini1036 – 1136101SRCR 10Add
BLAST
Domaini1141 – 1243103SRCR 11Add
BLAST
Domaini1246 – 1346101SRCR 12Add
BLAST

Sequence similaritiesi

Contains 12 SRCR domains.

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG83796.
HOGENOMiHOG000290652.
HOVERGENiHBG080943.
InParanoidiQ9NR16.
KOiK06545.
OMAiQLGCPFS.
OrthoDBiEOG7RNK07.
PhylomeDBiQ9NR16.
TreeFamiTF329295.

Family and domain databases

Gene3Di3.10.250.10. 12 hits.
InterProiIPR001190. SRCR.
IPR017448. SRCR-like_dom.
[Graphical view]
PfamiPF00530. SRCR. 12 hits.
[Graphical view]
PRINTSiPR00258. SPERACTRCPTR.
SMARTiSM00202. SR. 12 hits.
[Graphical view]
SUPFAMiSSF56487. SSF56487. 12 hits.
PROSITEiPS00420. SRCR_1. 5 hits.
PS50287. SRCR_2. 12 hits.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9NR16-1) [UniParc]FASTAAdd to Basket

Also known as: M160-alpha

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MMLPQNSWHI DFGRCCCHQN LFSAVVTCIL LLNSCFLISS FNGTDLELRL     50
VNGDGPCSGT VEVKFQGQWG TVCDDGWNTT ASTVVCKQLG CPFSFAMFRF 100
GQAVTRHGKI WLDDVSCYGN ESALWECQHR EWGSHNCYHG EDVGVNCYGE 150
ANLGLRLVDG NNSCSGRVEV KFQERWGTIC DDGWNLNTAA VVCRQLGCPS 200
SFISSGVVNS PAVLRPIWLD DILCQGNELA LWNCRHRGWG NHDCSHNEDV 250
TLTCYDSSDL ELRLVGGTNR CMGRVELKIQ GRWGTVCHHK WNNAAADVVC 300
KQLGCGTALH FAGLPHLQSG SDVVWLDGVS CSGNESFLWD CRHSGTVNFD 350
CLHQNDVSVI CSDGADLELR LADGSNNCSG RVEVRIHEQW WTICDQNWKN 400
EQALVVCKQL GCPFSVFGSR RAKPSNEARD IWINSISCTG NESALWDCTY 450
DGKAKRTCFR RSDAGVICSD KADLDLRLVG AHSPCYGRLE VKYQGEWGTV 500
CHDRWSTRNA AVVCKQLGCG KPLHVFGMTY FKEASGPIWL DDVSCIGNES 550
NIWDCEHSGW GKHNCVHRED VIVTCSGDAT WGLRLVGGSN RCSGRLEVYF 600
QGRWGTVCDD GWNSKAAAVV CSQLDCPSSI IGMGLGNAST GYGKIWLDDV 650
SCDGDESDLW SCRNSGWGNN DCSHSEDVGV ICSDASDMEL RLVGGSSRCA 700
GKVEVNVQGA VGILCANGWG MNIAEVVCRQ LECGSAIRVS REPHFTERTL 750
HILMSNSGCT GGEASLWDCI RWEWKQTACH LNMEASLICS AHRQPRLVGA 800
DMPCSGRVEV KHADTWRSVC DSDFSLHAAN VLCRELNCGD AISLSVGDHF 850
GKGNGLTWAE KFQCEGSETH LALCPIVQHP EDTCIHSREV GVVCSRYTDV 900
RLVNGKSQCD GQVEINVLGH WGSLCDTHWD PEDARVLCRQ LSCGTALSTT 950
GGKYIGERSV RVWGHRFHCL GNESLLDNCQ MTVLGAPPCI HGNTVSVICT 1000
GSLTQPLFPC LANVSDPYLS AVPEGSALIC LEDKRLRLVD GDSRCAGRVE 1050
IYHDGFWGTI CDDGWDLSDA HVVCQKLGCG VAFNATVSAH FGEGSGPIWL 1100
DDLNCTGMES HLWQCPSRGW GQHDCRHKED AGVICSEFTA LRLYSETETE 1150
SCAGRLEVFY NGTWGSVGRR NITTAIAGIV CRQLGCGENG VVSLAPLSKT 1200
GSGFMWVDDI QCPKTHISIW QCLSAPWERR ISSPAEETWI TCEDRIRVRG 1250
GDTECSGRVE IWHAGSWGTV CDDSWDLAEA EVVCQQLGCG SALAALRDAS 1300
FGQGTGTIWL DDMRCKGNES FLWDCHAKPW GQSDCGHKED AGVRCSGQSL 1350
KSLNASSGHL ALILSSIFGL LLLVLFILFL TWCRVQKQKH LPLRVSTRRR 1400
GSLEENLFHE METCLKREDP HGTRTSDDTP NHGCEDASDT SLLGVLPASE 1450
ATK 1453
Length:1,453
Mass (Da):159,239
Last modified:May 18, 2010 - v2
Checksum:iEBF90FBEE4FDF4CE
GO
Isoform 2 (identifier: Q9NR16-2) [UniParc]FASTAAdd to Basket

Also known as: M160-beta

The sequence of this isoform differs from the canonical sequence as follows:
     1395-1426: Missing.

Show »
Length:1,421
Mass (Da):155,484
Checksum:iE070F676F8099DBA
GO
Isoform 3 (identifier: Q9NR16-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     718-727: GWGMNIAEVV → SFLMTSSKPR
     728-1453: Missing.

Note: No experimental confirmation available.

Show »
Length:727
Mass (Da):79,769
Checksum:iF03D2BC09B1BD919
GO
Isoform 4 (identifier: Q9NR16-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     148-148: Y → YGKSLTRVGRQ

Note: No experimental confirmation available.

Show »
Length:1,463
Mass (Da):160,322
Checksum:iFAAF9E5EB74C9C40
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti523 – 5231L → M.5 Publications
Corresponds to variant rs6488268 [ dbSNP | Ensembl ].
VAR_059810
Natural varianti578 – 5781D → N.
Corresponds to variant rs4072797 [ dbSNP | Ensembl ].
VAR_057206
Natural varianti582 – 5821G → A.
Corresponds to variant rs4072796 [ dbSNP | Ensembl ].
VAR_057207
Natural varianti1055 – 10551G → S.
Corresponds to variant rs36206713 [ dbSNP | Ensembl ].
VAR_057208
Natural varianti1108 – 11081M → T.
Corresponds to variant rs35480970 [ dbSNP | Ensembl ].
VAR_057209

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei148 – 1481Y → YGKSLTRVGRQ in isoform 4. VSP_047557
Alternative sequencei718 – 72710GWGMNIAEVV → SFLMTSSKPR in isoform 3. VSP_016875
Alternative sequencei728 – 1453726Missing in isoform 3. VSP_016876Add
BLAST
Alternative sequencei1395 – 142632Missing in isoform 2. VSP_016877Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti105 – 1051T → S in BAG64429. 1 Publication
Sequence conflicti333 – 3331G → V in BAG64429. 1 Publication
Sequence conflicti1234 – 12341P → T in AAF91396. 1 Publication
Sequence conflicti1234 – 12341P → T in AAQ89215. 1 Publication
Sequence conflicti1359 – 13591H → R in AAF91396. 1 Publication
Sequence conflicti1359 – 13591H → R in AAQ89215. 1 Publication
Sequence conflicti1373 – 13731L → P in AAF91396. 1 Publication
Sequence conflicti1373 – 13731L → P in AAQ89215. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF264014 mRNA. Translation: AAF91396.1.
GQ397482 mRNA. Translation: ADB45259.1.
AY358856 mRNA. Translation: AAQ89215.1.
AK303372 mRNA. Translation: BAG64429.1.
AC131205 Genomic DNA. No translation available.
AC131206 Genomic DNA. No translation available.
AC131207 Genomic DNA. No translation available.
BC104962 mRNA. Translation: AAI04963.1.
BC104964 mRNA. Translation: AAI04965.1.
CCDSiCCDS8577.1. [Q9NR16-1]
RefSeqiNP_777601.2. NM_174941.4.
XP_005253405.1. XM_005253348.2. [Q9NR16-4]
UniGeneiHs.631727.

Genome annotation databases

EnsembliENST00000313599; ENSP00000315945; ENSG00000177675. [Q9NR16-1]
ENST00000396630; ENSP00000379871; ENSG00000177675. [Q9NR16-2]
ENST00000416109; ENSP00000393474; ENSG00000177675. [Q9NR16-4]
GeneIDi283316.
KEGGihsa:283316.
UCSCiuc001qsy.3. human.

Polymorphism databases

DMDMi296434413.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF264014 mRNA. Translation: AAF91396.1 .
GQ397482 mRNA. Translation: ADB45259.1 .
AY358856 mRNA. Translation: AAQ89215.1 .
AK303372 mRNA. Translation: BAG64429.1 .
AC131205 Genomic DNA. No translation available.
AC131206 Genomic DNA. No translation available.
AC131207 Genomic DNA. No translation available.
BC104962 mRNA. Translation: AAI04963.1 .
BC104964 mRNA. Translation: AAI04965.1 .
CCDSi CCDS8577.1. [Q9NR16-1 ]
RefSeqi NP_777601.2. NM_174941.4.
XP_005253405.1. XM_005253348.2. [Q9NR16-4 ]
UniGenei Hs.631727.

3D structure databases

ProteinModelPortali Q9NR16.
SMRi Q9NR16. Positions 45-153, 155-260, 262-362, 366-474, 487-576, 583-683, 686-790, 796-898, 900-1000, 1031-1141, 1246-1349.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9606.ENSP00000315945.

PTM databases

PhosphoSitei Q9NR16.

Polymorphism databases

DMDMi 296434413.

Proteomic databases

PaxDbi Q9NR16.
PRIDEi Q9NR16.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000313599 ; ENSP00000315945 ; ENSG00000177675 . [Q9NR16-1 ]
ENST00000396630 ; ENSP00000379871 ; ENSG00000177675 . [Q9NR16-2 ]
ENST00000416109 ; ENSP00000393474 ; ENSG00000177675 . [Q9NR16-4 ]
GeneIDi 283316.
KEGGi hsa:283316.
UCSCi uc001qsy.3. human.

Organism-specific databases

CTDi 283316.
GeneCardsi GC12M007507.
HGNCi HGNC:30375. CD163L1.
HPAi HPA015663.
MIMi 606079. gene.
neXtProti NX_Q9NR16.
PharmGKBi PA142672145.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG83796.
HOGENOMi HOG000290652.
HOVERGENi HBG080943.
InParanoidi Q9NR16.
KOi K06545.
OMAi QLGCPFS.
OrthoDBi EOG7RNK07.
PhylomeDBi Q9NR16.
TreeFami TF329295.

Miscellaneous databases

ChiTaRSi CD163L1. human.
GenomeRNAii 283316.
NextBioi 35476751.
PROi Q9NR16.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q9NR16.
Bgeei Q9NR16.
CleanExi HS_CD163L1.
Genevestigatori Q9NR16.

Family and domain databases

Gene3Di 3.10.250.10. 12 hits.
InterProi IPR001190. SRCR.
IPR017448. SRCR-like_dom.
[Graphical view ]
Pfami PF00530. SRCR. 12 hits.
[Graphical view ]
PRINTSi PR00258. SPERACTRCPTR.
SMARTi SM00202. SR. 12 hits.
[Graphical view ]
SUPFAMi SSF56487. SSF56487. 12 hits.
PROSITEi PS00420. SRCR_1. 5 hits.
PS50287. SRCR_2. 12 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning of a novel scavenger receptor cysteine-rich type I transmembrane molecule (M160) expressed by human macrophages."
    Groenlund J., Vitved L., Lausen M., Skjoedt K., Holmskov U.
    J. Immunol. 165:6406-6415(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), TISSUE SPECIFICITY, VARIANT MET-523.
  2. "Identification of the CD163 protein domains involved in infection of the porcine reproductive and respiratory syndrome virus."
    Van Gorp H., Van Breedam W., Van Doorsselaere J., Delputte P.L., Nauwynck H.J.
    J. Virol. 84:3101-3105(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT MET-523.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), VARIANT MET-523.
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4), VARIANT MET-523.
    Tissue: Thymus.
  5. "The finished DNA sequence of human chromosome 12."
    Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
    , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A.
    Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT MET-523.
    Tissue: Heart and Lung.
  7. "Signal peptide prediction based on analysis of experimentally verified cleavage sites."
    Zhang Z., Henzel W.J.
    Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 41-55.
  8. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
    Chen R., Jiang X., Sun D., Han G., Wang F., Ye M., Wang L., Zou H.
    J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-1161.
    Tissue: Liver.

Entry informationi

Entry nameiC163B_HUMAN
AccessioniPrimary (citable) accession number: Q9NR16
Secondary accession number(s): B4E0G7
, C9JHR7, E7EVK4, Q2M3B7, Q6UWC2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: May 18, 2010
Last modified: July 9, 2014
This is version 102 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human cell differentiation molecules
    CD nomenclature of surface proteins of human leucocytes and list of entries
  2. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi