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Q9NR16 (C163B_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 99. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (6) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Scavenger receptor cysteine-rich type 1 protein M160
Alternative name(s):
CD163 antigen-like 1
CD_antigen=CD163b
Gene names
Name:CD163L1
Synonyms:CD163B, M160
ORF Names:UNQ6434/PRO23202
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length1453 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Isoform 1: Cell membrane; Single-pass type I membrane protein Probable.

Isoform 2: Cell membrane; Single-pass type I membrane protein Probable.

Isoform 3: Secreted Probable.

Tissue specificity

Isoform 1 is highly expressed in the spleen, lymph nodes, thymus, and fetal liver and weakly expressed in bone marrow and no expression was found in peripheral blood leukocytes. Isoform 1 expression is restricted to the monocyte and macrophage cell lines. Isoform 2 is only expressed in spleen. Ref.1

Sequence similarities

Contains 12 SRCR domains.

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q9NR16-1)

Also known as: M160-alpha;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q9NR16-2)

Also known as: M160-beta;

The sequence of this isoform differs from the canonical sequence as follows:
     1395-1426: Missing.
Isoform 3 (identifier: Q9NR16-3)

The sequence of this isoform differs from the canonical sequence as follows:
     718-727: GWGMNIAEVV → SFLMTSSKPR
     728-1453: Missing.
Note: No experimental confirmation available.
Isoform 4 (identifier: Q9NR16-4)

The sequence of this isoform differs from the canonical sequence as follows:
     148-148: Y → YGKSLTRVGRQ
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 4040 Ref.7
Chain41 – 14531413Scavenger receptor cysteine-rich type 1 protein M160
PRO_0000045392

Regions

Topological domain41 – 13591319Extracellular Potential
Transmembrane1360 – 138021Helical; Potential
Topological domain1381 – 145373Cytoplasmic Potential
Domain48 – 148101SRCR 1
Domain155 – 255101SRCR 2
Domain262 – 362101SRCR 3
Domain369 – 469101SRCR 4
Domain476 – 576101SRCR 5
Domain583 – 683101SRCR 6
Domain690 – 790101SRCR 7
Domain795 – 895101SRCR 8
Domain900 – 1000101SRCR 9
Domain1036 – 1136101SRCR 10
Domain1141 – 1243103SRCR 11
Domain1246 – 1346101SRCR 12

Amino acid modifications

Glycosylation421N-linked (GlcNAc...) Potential
Glycosylation781N-linked (GlcNAc...) Potential
Glycosylation1201N-linked (GlcNAc...) Potential
Glycosylation1611N-linked (GlcNAc...) Potential
Glycosylation3341N-linked (GlcNAc...) Potential
Glycosylation3771N-linked (GlcNAc...) Potential
Glycosylation4411N-linked (GlcNAc...) Potential
Glycosylation5481N-linked (GlcNAc...) Potential
Glycosylation6371N-linked (GlcNAc...) Potential
Glycosylation9721N-linked (GlcNAc...) Potential
Glycosylation10131N-linked (GlcNAc...) Potential
Glycosylation10841N-linked (GlcNAc...) Potential
Glycosylation11041N-linked (GlcNAc...) Potential
Glycosylation11611N-linked (GlcNAc...) Ref.8
Glycosylation11711N-linked (GlcNAc...) Potential
Glycosylation13181N-linked (GlcNAc...) Potential
Glycosylation13541N-linked (GlcNAc...) Potential
Disulfide bond73 ↔ 137 By similarity
Disulfide bond86 ↔ 147 By similarity
Disulfide bond117 ↔ 127 By similarity
Disulfide bond180 ↔ 244 By similarity
Disulfide bond193 ↔ 254 By similarity
Disulfide bond224 ↔ 234 By similarity
Disulfide bond287 ↔ 351 By similarity
Disulfide bond300 ↔ 361 By similarity
Disulfide bond331 ↔ 341 By similarity
Disulfide bond394 ↔ 458 By similarity
Disulfide bond407 ↔ 468 By similarity
Disulfide bond438 ↔ 448 By similarity
Disulfide bond501 ↔ 565 By similarity
Disulfide bond514 ↔ 575 By similarity
Disulfide bond545 ↔ 555 By similarity
Disulfide bond608 ↔ 672 By similarity
Disulfide bond621 ↔ 682 By similarity
Disulfide bond652 ↔ 662 By similarity
Disulfide bond715 ↔ 779 By similarity
Disulfide bond728 ↔ 789 By similarity
Disulfide bond759 ↔ 769 By similarity
Disulfide bond820 ↔ 884 By similarity
Disulfide bond833 ↔ 894 By similarity
Disulfide bond864 ↔ 874 By similarity
Disulfide bond925 ↔ 989 By similarity
Disulfide bond938 ↔ 999 By similarity
Disulfide bond969 ↔ 979 By similarity
Disulfide bond1061 ↔ 1125 By similarity
Disulfide bond1074 ↔ 1135 By similarity
Disulfide bond1105 ↔ 1115 By similarity
Disulfide bond1181 ↔ 1242 By similarity
Disulfide bond1212 ↔ 1222 By similarity
Disulfide bond1271 ↔ 1335 By similarity
Disulfide bond1284 ↔ 1345 By similarity
Disulfide bond1315 ↔ 1325 By similarity

Natural variations

Alternative sequence1481Y → YGKSLTRVGRQ in isoform 4.
VSP_047557
Alternative sequence718 – 72710GWGMNIAEVV → SFLMTSSKPR in isoform 3.
VSP_016875
Alternative sequence728 – 1453726Missing in isoform 3.
VSP_016876
Alternative sequence1395 – 142632Missing in isoform 2.
VSP_016877
Natural variant5231L → M. Ref.1 Ref.2 Ref.3 Ref.4 Ref.6
Corresponds to variant rs6488268 [ dbSNP | Ensembl ].
VAR_059810
Natural variant5781D → N.
Corresponds to variant rs4072797 [ dbSNP | Ensembl ].
VAR_057206
Natural variant5821G → A.
Corresponds to variant rs4072796 [ dbSNP | Ensembl ].
VAR_057207
Natural variant10551G → S.
Corresponds to variant rs36206713 [ dbSNP | Ensembl ].
VAR_057208
Natural variant11081M → T.
Corresponds to variant rs35480970 [ dbSNP | Ensembl ].
VAR_057209

Experimental info

Sequence conflict1051T → S in BAG64429. Ref.4
Sequence conflict3331G → V in BAG64429. Ref.4
Sequence conflict12341P → T in AAF91396. Ref.1
Sequence conflict12341P → T in AAQ89215. Ref.3
Sequence conflict13591H → R in AAF91396. Ref.1
Sequence conflict13591H → R in AAQ89215. Ref.3
Sequence conflict13731L → P in AAF91396. Ref.1
Sequence conflict13731L → P in AAQ89215. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 (M160-alpha) [UniParc].

Last modified May 18, 2010. Version 2.
Checksum: EBF90FBEE4FDF4CE

FASTA1,453159,239
        10         20         30         40         50         60 
MMLPQNSWHI DFGRCCCHQN LFSAVVTCIL LLNSCFLISS FNGTDLELRL VNGDGPCSGT 

        70         80         90        100        110        120 
VEVKFQGQWG TVCDDGWNTT ASTVVCKQLG CPFSFAMFRF GQAVTRHGKI WLDDVSCYGN 

       130        140        150        160        170        180 
ESALWECQHR EWGSHNCYHG EDVGVNCYGE ANLGLRLVDG NNSCSGRVEV KFQERWGTIC 

       190        200        210        220        230        240 
DDGWNLNTAA VVCRQLGCPS SFISSGVVNS PAVLRPIWLD DILCQGNELA LWNCRHRGWG 

       250        260        270        280        290        300 
NHDCSHNEDV TLTCYDSSDL ELRLVGGTNR CMGRVELKIQ GRWGTVCHHK WNNAAADVVC 

       310        320        330        340        350        360 
KQLGCGTALH FAGLPHLQSG SDVVWLDGVS CSGNESFLWD CRHSGTVNFD CLHQNDVSVI 

       370        380        390        400        410        420 
CSDGADLELR LADGSNNCSG RVEVRIHEQW WTICDQNWKN EQALVVCKQL GCPFSVFGSR 

       430        440        450        460        470        480 
RAKPSNEARD IWINSISCTG NESALWDCTY DGKAKRTCFR RSDAGVICSD KADLDLRLVG 

       490        500        510        520        530        540 
AHSPCYGRLE VKYQGEWGTV CHDRWSTRNA AVVCKQLGCG KPLHVFGMTY FKEASGPIWL 

       550        560        570        580        590        600 
DDVSCIGNES NIWDCEHSGW GKHNCVHRED VIVTCSGDAT WGLRLVGGSN RCSGRLEVYF 

       610        620        630        640        650        660 
QGRWGTVCDD GWNSKAAAVV CSQLDCPSSI IGMGLGNAST GYGKIWLDDV SCDGDESDLW 

       670        680        690        700        710        720 
SCRNSGWGNN DCSHSEDVGV ICSDASDMEL RLVGGSSRCA GKVEVNVQGA VGILCANGWG 

       730        740        750        760        770        780 
MNIAEVVCRQ LECGSAIRVS REPHFTERTL HILMSNSGCT GGEASLWDCI RWEWKQTACH 

       790        800        810        820        830        840 
LNMEASLICS AHRQPRLVGA DMPCSGRVEV KHADTWRSVC DSDFSLHAAN VLCRELNCGD 

       850        860        870        880        890        900 
AISLSVGDHF GKGNGLTWAE KFQCEGSETH LALCPIVQHP EDTCIHSREV GVVCSRYTDV 

       910        920        930        940        950        960 
RLVNGKSQCD GQVEINVLGH WGSLCDTHWD PEDARVLCRQ LSCGTALSTT GGKYIGERSV 

       970        980        990       1000       1010       1020 
RVWGHRFHCL GNESLLDNCQ MTVLGAPPCI HGNTVSVICT GSLTQPLFPC LANVSDPYLS 

      1030       1040       1050       1060       1070       1080 
AVPEGSALIC LEDKRLRLVD GDSRCAGRVE IYHDGFWGTI CDDGWDLSDA HVVCQKLGCG 

      1090       1100       1110       1120       1130       1140 
VAFNATVSAH FGEGSGPIWL DDLNCTGMES HLWQCPSRGW GQHDCRHKED AGVICSEFTA 

      1150       1160       1170       1180       1190       1200 
LRLYSETETE SCAGRLEVFY NGTWGSVGRR NITTAIAGIV CRQLGCGENG VVSLAPLSKT 

      1210       1220       1230       1240       1250       1260 
GSGFMWVDDI QCPKTHISIW QCLSAPWERR ISSPAEETWI TCEDRIRVRG GDTECSGRVE 

      1270       1280       1290       1300       1310       1320 
IWHAGSWGTV CDDSWDLAEA EVVCQQLGCG SALAALRDAS FGQGTGTIWL DDMRCKGNES 

      1330       1340       1350       1360       1370       1380 
FLWDCHAKPW GQSDCGHKED AGVRCSGQSL KSLNASSGHL ALILSSIFGL LLLVLFILFL 

      1390       1400       1410       1420       1430       1440 
TWCRVQKQKH LPLRVSTRRR GSLEENLFHE METCLKREDP HGTRTSDDTP NHGCEDASDT 

      1450 
SLLGVLPASE ATK 

« Hide

Isoform 2 (M160-beta) [UniParc].

Checksum: E070F676F8099DBA
Show »

FASTA1,421155,484
Isoform 3 [UniParc].

Checksum: F03D2BC09B1BD919
Show »

FASTA72779,769
Isoform 4 [UniParc].

Checksum: FAAF9E5EB74C9C40
Show »

FASTA1,463160,322

References

« Hide 'large scale' references
[1]"Cloning of a novel scavenger receptor cysteine-rich type I transmembrane molecule (M160) expressed by human macrophages."
Groenlund J., Vitved L., Lausen M., Skjoedt K., Holmskov U.
J. Immunol. 165:6406-6415(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), TISSUE SPECIFICITY, VARIANT MET-523.
[2]"Identification of the CD163 protein domains involved in infection of the porcine reproductive and respiratory syndrome virus."
Van Gorp H., Van Breedam W., Van Doorsselaere J., Delputte P.L., Nauwynck H.J.
J. Virol. 84:3101-3105(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT MET-523.
[3]"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J., Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P., Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E. expand/collapse author list , Heldens S., Huang A., Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D., Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L., Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C., Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J., Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M.
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), VARIANT MET-523.
[4]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4), VARIANT MET-523.
Tissue: Thymus.
[5]"The finished DNA sequence of human chromosome 12."
Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R. expand/collapse author list , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A.
Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[6]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT MET-523.
Tissue: Heart and Lung.
[7]"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Zhang Z., Henzel W.J.
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 41-55.
[8]"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R., Jiang X., Sun D., Han G., Wang F., Ye M., Wang L., Zou H.
J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-1161.
Tissue: Liver.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF264014 mRNA. Translation: AAF91396.1.
GQ397482 mRNA. Translation: ADB45259.1.
AY358856 mRNA. Translation: AAQ89215.1.
AK303372 mRNA. Translation: BAG64429.1.
AC131205 Genomic DNA. No translation available.
AC131206 Genomic DNA. No translation available.
AC131207 Genomic DNA. No translation available.
BC104962 mRNA. Translation: AAI04963.1.
BC104964 mRNA. Translation: AAI04965.1.
RefSeqNP_777601.2. NM_174941.4.
XP_005253405.1. XM_005253348.2.
UniGeneHs.631727.

3D structure databases

ProteinModelPortalQ9NR16.
SMRQ9NR16. Positions 45-255, 262-362, 366-474, 487-576, 583-683, 686-790, 796-898, 900-1000, 1032-1349.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9606.ENSP00000315945.

PTM databases

PhosphoSiteQ9NR16.

Polymorphism databases

DMDM296434413.

Proteomic databases

PaxDbQ9NR16.
PRIDEQ9NR16.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000313599; ENSP00000315945; ENSG00000177675. [Q9NR16-1]
ENST00000396630; ENSP00000379871; ENSG00000177675. [Q9NR16-2]
ENST00000416109; ENSP00000393474; ENSG00000177675. [Q9NR16-4]
GeneID283316.
KEGGhsa:283316.
UCSCuc001qsy.3. human.

Organism-specific databases

CTD283316.
GeneCardsGC12M007507.
HGNCHGNC:30375. CD163L1.
HPAHPA015663.
MIM606079. gene.
neXtProtNX_Q9NR16.
PharmGKBPA142672145.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG83796.
HOGENOMHOG000290652.
HOVERGENHBG080943.
InParanoidQ9NR16.
KOK06545.
OMAQLGCPFS.
OrthoDBEOG7RNK07.
PhylomeDBQ9NR16.
TreeFamTF329295.

Gene expression databases

ArrayExpressQ9NR16.
BgeeQ9NR16.
CleanExHS_CD163L1.
GenevestigatorQ9NR16.

Family and domain databases

Gene3D3.10.250.10. 12 hits.
InterProIPR001190. SRCR.
IPR017448. SRCR-like_dom.
[Graphical view]
PfamPF00530. SRCR. 12 hits.
[Graphical view]
PRINTSPR00258. SPERACTRCPTR.
SMARTSM00202. SR. 12 hits.
[Graphical view]
SUPFAMSSF56487. SSF56487. 12 hits.
PROSITEPS00420. SRCR_1. 5 hits.
PS50287. SRCR_2. 12 hits.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSCD163L1. human.
GenomeRNAi283316.
NextBio35476751.
PROQ9NR16.
SOURCESearch...

Entry information

Entry nameC163B_HUMAN
AccessionPrimary (citable) accession number: Q9NR16
Secondary accession number(s): B4E0G7 expand/collapse secondary AC list , C9JHR7, E7EVK4, Q2M3B7, Q6UWC2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: May 18, 2010
Last modified: April 16, 2014
This is version 99 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 12

Human chromosome 12: entries, gene names and cross-references to MIM

Human cell differentiation molecules

CD nomenclature of surface proteins of human leucocytes and list of entries