Q9NQW1 (SC31B_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein transport protein Sec31B

Alternative name(s):
SEC31-like protein 2
SEC31-related protein B
SEC31B-1

Gene names

Name:	SEC31B
Synonyms:	SEC31L2

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1179 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	As a component of the coat protein complex II (COPII), may function in vesicle budding and cargo export from the endoplasmic reticulum. Ref.1
Subunit structure	COPII is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex and SAR1. SEC13 and SEC31 make a 2:2 tetramer that forms the edge element of the COPII outer coat. The tetramer self-assembles in multiple copies to form the complete polyhedral cage. Interacts (via WD 8) with SEC13 By similarity. Interacts with SEC31A. Ref.1
Subcellular location	Cytoplasm. Cytoplasmic vesicle › COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein Ref.1.
Tissue specificity	Ubiquitously expressed at low levels with specific expression in thymus and testis. Expressed in testis by Sertoli cells, Leydig cells and spermatogonia and in cerebellum more prominently by Purkinje and granular cells (at protein level). Ref.1 Ref.5
Post-translational modification	Monoubiquitinated by the BCR(KLHL12) E3 ubiquitin ligase complex, leading to regulate the size of COPII coats.
Sequence similarities	Belongs to the WD repeat SEC31 family. Contains 8 WD repeats.

Ontologies

Keywords
Biological process	ER-Golgi transport Protein transport Transport
Cellular component	Cytoplasm Cytoplasmic vesicle Endoplasmic reticulum Membrane
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Repeat WD repeat
PTM	Phosphoprotein Ubl conjugation
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	protein transport Inferred from electronic annotation. Source: UniProtKB-KW vesicle-mediated transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	ER to Golgi transport vesicle membrane Inferred from electronic annotation. Source: UniProtKB-SubCell endoplasmic reticulum membrane Inferred from electronic annotation. Source: UniProtKB-SubCell endoplasmic reticulum part Inferred from direct assay PubMed 22792322. Source: MGI
Complete GO annotation...

Alternative products

This entry describes 5 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q9NQW1-1)

Also known as: SEC31B-F;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q9NQW1-2)

The sequence of this isoform differs from the canonical sequence as follows:
     165-165: Missing.
     349-349: I → V
     350-1179: Missing.

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

Isoform 3 (identifier: Q9NQW1-3)

The sequence of this isoform differs from the canonical sequence as follows:
     69-85: FHKLVWGSFGSGLLESS → ATSWLQGPAILKSSLGI
     86-1179: Missing.

Isoform 4 (identifier: Q9NQW1-4)

Also known as: SEC31B-t;

The sequence of this isoform differs from the canonical sequence as follows:
     470-482: KVTLEQDSRMKFL → KPARDSSGARR
     483-1179: Missing.

Isoform 5 (identifier: Q9NQW1-5)

The sequence of this isoform differs from the canonical sequence as follows:
     165-165: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1179	1179	Protein transport protein Sec31B		PRO_0000295153
Regions
	Repeat	17 – 56	40	WD 1
	Repeat	67 – 110	44	WD 2
	Repeat	119 – 159	41	WD 3
	Repeat	166 – 206	41	WD 4
	Repeat	209 – 254	46	WD 5
	Repeat	258 – 298	41	WD 6
	Repeat	301 – 341	41	WD 7
	Repeat	391 – 422	32	WD 8; interaction with SEC13 By similarity
	Compositional bias	821 – 1073	253	Pro-rich
Amino acid modifications
	Modified residue	679	1	Phosphothreonine By similarity
	Modified residue	680	1	Phosphoserine By similarity
Natural variations
	Alternative sequence	69 – 85	17	FHKLV…LLESS → ATSWLQGPAILKSSLGI in isoform 3.		VSP_026757
	Alternative sequence	86 – 1179	1094	Missing in isoform 3.		VSP_026758
	Alternative sequence	165	1	Missing in isoform 2 and isoform 5.		VSP_026759
	Alternative sequence	349	1	I → V in isoform 2.		VSP_026760
	Alternative sequence	350 – 1179	830	Missing in isoform 2.		VSP_026761
	Alternative sequence	470 – 482	13	KVTLE…RMKFL → KPARDSSGARR in isoform 4.		VSP_026762
	Alternative sequence	483 – 1179	697	Missing in isoform 4.		VSP_026763
	Natural variant	89	1	V → A. Ref.4 Corresponds to variant rs3763695 [ dbSNP | Ensembl ].		VAR_033228
	Natural variant	100	1	Y → C. Corresponds to variant rs7074707 [ dbSNP | Ensembl ].		VAR_033229
	Natural variant	129	1	L → F. Ref.4 Corresponds to variant rs3793706 [ dbSNP | Ensembl ].		VAR_033230
	Natural variant	332	1	S → A. Ref.4 Corresponds to variant rs2295774 [ dbSNP | Ensembl ].		VAR_033231
	Natural variant	372	1	P → S. Corresponds to variant rs2295772 [ dbSNP | Ensembl ].		VAR_033232
	Natural variant	433	1	R → Q. Corresponds to variant rs2295771 [ dbSNP | Ensembl ].		VAR_053415
	Natural variant	478	1	R → T. Corresponds to variant rs11819496 [ dbSNP | Ensembl ].		VAR_053416
	Natural variant	527	1	S → R. Corresponds to variant rs17113157 [ dbSNP | Ensembl ].		VAR_033233
	Natural variant	1169	1	A → S. Corresponds to variant rs2298075 [ dbSNP | Ensembl ].		VAR_033234
Experimental info
	Sequence conflict	805	1	A → V in CAB45735. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 (SEC31B-F) [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 88C591B060643A5D	FASTA	1,179	128,697
	10 20 30 40 50 60 MKLKELERPA VQAWSPASQY PLYLATGTSA QQLDSSFSTN GTLEIFEVDF RDPSLDLKHR 70 80 90 100 110 120 GVLSALSRFH KLVWGSFGSG LLESSGVIVG GGDNGMLILY NVTHILSSGK EPVIAQKQKH 130 140 150 160 170 180 TGAVRALDLN PFQGNLLASG ASDSEIFIWD LNNLNVPMTL GSKSQQPPED IKALSWNRQA 190 200 210 220 230 240 QHILSSAHPS GKAVVWDLRK NEPIIKVSDH SNRMHCSGLA WHPDIATQLV LCSEDDRLPV 250 260 270 280 290 300 IQLWDLRFAS SPLKVLESHS RGILSVSWSQ ADAELLLTSA KDSQILCRNL GSSEVVYKLP 310 320 330 340 350 360 TQSSWCFDVQ WCPRDPSVFS AASFNGWISL YSVMGRSWEV QHMRQADKIS SSFSKGQPLP 370 380 390 400 410 420 PLQVPEQVAQ APLIPPLKKP PKWIRRPTGV SFAFGGKLVT FGLPSTPAHL VPQPCPRLVF 430 440 450 460 470 480 ISQVTTESEF LMRSAELQEA LGSGNLLNYC QNKSQQALLQ SEKMLWQFLK VTLEQDSRMK 490 500 510 520 530 540 FLKLLGYSKD ELQKKVATWL KSDVGLGESP QPKGNDLNSD RQQAFCSQAS KHTTKEASAS 550 560 570 580 590 600 SAFFDELVPQ NMTPWEIPIT KDIDGLLSQA LLLGELGPAV ELCLKEERFA DAIILAQAGG 610 620 630 640 650 660 TDLLKQTQER YLAKKKTKIS SLLACVVQKN WKDVVCTCSL KNWREALALL LTYSGTEKFP 670 680 690 700 710 720 ELCDMLGTRM EQEGSRALTS EARLCYVCSG SVERLVECWA KCHQALSPMA LQDLMEKVMV 730 740 750 760 770 780 LNRSLEQLRG PHGVSPGPAT TYRVTQYANL LAAQGSLATA MSFLPRDCAQ PPVQQLRDRL 790 800 810 820 830 840 FHAQGSAVLG QQSPPFPFPR IVVGATLHSK ETSSYRLGSQ PSHQVPTPSP RPRVFTPQSS 850 860 870 880 890 900 PAMPLAPSHP SPYQGPRTQN ISDYRAPGPQ AIQPLPLSPG VRPASSQPQL LGGQRVQVPN 910 920 930 940 950 960 PVGFPGTWPL PGSPLPMACP GIMRPGSTSL PETPRLFPLL PLRPLGPGRM VSHTPAPPAS 970 980 990 1000 1010 1020 FPVPYLPGDP GAPCSSVLPT TGILTPHPGP QDSWKEAPAP RGNLQRNKLP ETFMPPAPIT 1030 1040 1050 1060 1070 1080 APVMSLTPEL QGILPSQPPV SSVSHAPPGV PGELSLQLQH LPPEKMERKE LPPEHQSLKS 1090 1100 1110 1120 1130 1140 SFEALLQRCS LSATDLKTKR KLEEAAQRLE YLYEKLCEGT LSPHVVAGLH EVARCVDAGS 1150 1160 1170 FEQGLAVHAQ VAGCSSFSEV SSFMPILKAV LIIAHKLLV
	Isoform 2 [UniParc]. Checksum: BD8A60259743B860	FASTA	348	38,450
	10 20 30 40 50 60 MKLKELERPA VQAWSPASQY PLYLATGTSA QQLDSSFSTN GTLEIFEVDF RDPSLDLKHR 70 80 90 100 110 120 GVLSALSRFH KLVWGSFGSG LLESSGVIVG GGDNGMLILY NVTHILSSGK EPVIAQKQKH 130 140 150 160 170 180 TGAVRALDLN PFQGNLLASG ASDSEIFIWD LNNLNVPMTL GSKSQPPEDI KALSWNRQAQ 190 200 210 220 230 240 HILSSAHPSG KAVVWDLRKN EPIIKVSDHS NRMHCSGLAW HPDIATQLVL CSEDDRLPVI 250 260 270 280 290 300 QLWDLRFASS PLKVLESHSR GILSVSWSQA DAELLLTSAK DSQILCRNLG SSEVVYKLPT 310 320 330 340 QSSWCFDVQW CPRDPSVFSA ASFNGWISLY SVMGRSWEVQ HMRQADKV
	Isoform 3 [UniParc]. Checksum: 1CA9C2A4C9F56411	FASTA	85	9,294
	10 20 30 40 50 60 MKLKELERPA VQAWSPASQY PLYLATGTSA QQLDSSFSTN GTLEIFEVDF RDPSLDLKHR 70 80 GVLSALSRAT SWLQGPAILK SSLGI
	Isoform 4 (SEC31B-t) [UniParc]. Checksum: A91F37DAA6824103	FASTA	480	52,984
	10 20 30 40 50 60 MKLKELERPA VQAWSPASQY PLYLATGTSA QQLDSSFSTN GTLEIFEVDF RDPSLDLKHR 70 80 90 100 110 120 GVLSALSRFH KLVWGSFGSG LLESSGVIVG GGDNGMLILY NVTHILSSGK EPVIAQKQKH 130 140 150 160 170 180 TGAVRALDLN PFQGNLLASG ASDSEIFIWD LNNLNVPMTL GSKSQQPPED IKALSWNRQA 190 200 210 220 230 240 QHILSSAHPS GKAVVWDLRK NEPIIKVSDH SNRMHCSGLA WHPDIATQLV LCSEDDRLPV 250 260 270 280 290 300 IQLWDLRFAS SPLKVLESHS RGILSVSWSQ ADAELLLTSA KDSQILCRNL GSSEVVYKLP 310 320 330 340 350 360 TQSSWCFDVQ WCPRDPSVFS AASFNGWISL YSVMGRSWEV QHMRQADKIS SSFSKGQPLP 370 380 390 400 410 420 PLQVPEQVAQ APLIPPLKKP PKWIRRPTGV SFAFGGKLVT FGLPSTPAHL VPQPCPRLVF 430 440 450 460 470 480 ISQVTTESEF LMRSAELQEA LGSGNLLNYC QNKSQQALLQ SEKMLWQFLK PARDSSGARR
	Isoform 5 [UniParc]. Checksum: 102AA849D41A1D65	FASTA	1,178	128,569
	10 20 30 40 50 60 MKLKELERPA VQAWSPASQY PLYLATGTSA QQLDSSFSTN GTLEIFEVDF RDPSLDLKHR 70 80 90 100 110 120 GVLSALSRFH KLVWGSFGSG LLESSGVIVG GGDNGMLILY NVTHILSSGK EPVIAQKQKH 130 140 150 160 170 180 TGAVRALDLN PFQGNLLASG ASDSEIFIWD LNNLNVPMTL GSKSQPPEDI KALSWNRQAQ 190 200 210 220 230 240 HILSSAHPSG KAVVWDLRKN EPIIKVSDHS NRMHCSGLAW HPDIATQLVL CSEDDRLPVI 250 260 270 280 290 300 QLWDLRFASS PLKVLESHSR GILSVSWSQA DAELLLTSAK DSQILCRNLG SSEVVYKLPT 310 320 330 340 350 360 QSSWCFDVQW CPRDPSVFSA ASFNGWISLY SVMGRSWEVQ HMRQADKISS SFSKGQPLPP 370 380 390 400 410 420 LQVPEQVAQA PLIPPLKKPP KWIRRPTGVS FAFGGKLVTF GLPSTPAHLV PQPCPRLVFI 430 440 450 460 470 480 SQVTTESEFL MRSAELQEAL GSGNLLNYCQ NKSQQALLQS EKMLWQFLKV TLEQDSRMKF 490 500 510 520 530 540 LKLLGYSKDE LQKKVATWLK SDVGLGESPQ PKGNDLNSDR QQAFCSQASK HTTKEASASS 550 560 570 580 590 600 AFFDELVPQN MTPWEIPITK DIDGLLSQAL LLGELGPAVE LCLKEERFAD AIILAQAGGT 610 620 630 640 650 660 DLLKQTQERY LAKKKTKISS LLACVVQKNW KDVVCTCSLK NWREALALLL TYSGTEKFPE 670 680 690 700 710 720 LCDMLGTRME QEGSRALTSE ARLCYVCSGS VERLVECWAK CHQALSPMAL QDLMEKVMVL 730 740 750 760 770 780 NRSLEQLRGP HGVSPGPATT YRVTQYANLL AAQGSLATAM SFLPRDCAQP PVQQLRDRLF 790 800 810 820 830 840 HAQGSAVLGQ QSPPFPFPRI VVGATLHSKE TSSYRLGSQP SHQVPTPSPR PRVFTPQSSP 850 860 870 880 890 900 AMPLAPSHPS PYQGPRTQNI SDYRAPGPQA IQPLPLSPGV RPASSQPQLL GGQRVQVPNP 910 920 930 940 950 960 VGFPGTWPLP GSPLPMACPG IMRPGSTSLP ETPRLFPLLP LRPLGPGRMV SHTPAPPASF 970 980 990 1000 1010 1020 PVPYLPGDPG APCSSVLPTT GILTPHPGPQ DSWKEAPAPR GNLQRNKLPE TFMPPAPITA 1030 1040 1050 1060 1070 1080 PVMSLTPELQ GILPSQPPVS SVSHAPPGVP GELSLQLQHL PPEKMERKEL PPEHQSLKSS 1090 1100 1110 1120 1130 1140 FEALLQRCSL SATDLKTKRK LEEAAQRLEY LYEKLCEGTL SPHVVAGLHE VARCVDAGSF 1150 1160 1170 EQGLAVHAQV AGCSSFSEVS SFMPILKAVL IIAHKLLV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Human Sec31B: a family of new mammalian orthologues of yeast Sec31p that associate with the COPII coat." Stankewich M.C., Stabach P.R., Morrow J.S. J. Cell Sci. 119:958-969(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), ALTERNATIVE SPLICING (ISOFORM 4), FUNCTION, TISSUE SPECIFICITY, SUBCELLULAR LOCATION, INTERACTION WITH SEC13 AND SEC31A. Tissue: Testis.
[2]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 265-1179 (ISOFORM 1). Tissue: Testis.
[3]	"The DNA sequence and comparative analysis of human chromosome 10." Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J. , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J. Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 5), VARIANTS ALA-89; PHE-129 AND ALA-332. Tissue: Testis.
[5]	"Mammalian homologues of yeast sec31p. An ubiquitously expressed form is localized to endoplasmic reticulum (ER) exit sites and is essential for ER-Golgi transport." Tang B.L., Zhang T., Low D.Y.H., Wong E.T., Horstmann H., Hong W. J. Biol. Chem. 275:13597-13604(2000) [PubMed] [Europe PMC] [Abstract] Cited for: TISSUE SPECIFICITY.
[6]	"Ubiquitin-dependent regulation of COPII coat size and function." Jin L., Pahuja K.B., Wickliffe K.E., Gorur A., Baumgartel C., Schekman R., Rape M. Nature 482:495-500(2012) [PubMed] [Europe PMC] [Abstract] Cited for: UBIQUITINATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF274863 mRNA. Translation: AAF78243.1. AL080141 mRNA. Translation: CAB45735.1. BX640914 mRNA. Translation: CAE45955.1. AL133352 Genomic DNA. Translation: CAH73561.1. BC034946 mRNA. Translation: AAH34946.1. BC044569 mRNA. No translation available. BC144313 mRNA. Translation: AAI44314.1.
IPI	IPI00023442. IPI00426029. IPI00853086. IPI00923389. IPI00954279.
PIR	T12526.
RefSeq	NP_056305.1. NM_015490.3.
UniGene	Hs.18889.
3D structure databases
ProteinModelPortal	Q9NQW1.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9NQW1. 1 interaction.
STRING	9606.ENSP00000359370.
PTM databases
PhosphoSite	Q9NQW1.
Polymorphism databases
DMDM	74762753.
Proteomic databases
PaxDb	Q9NQW1.
PRIDE	Q9NQW1.
Protocols and materials databases
DNASU	25956.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000370345; ENSP00000359370; ENSG00000075826. ENST00000451524; ENSP00000391178; ENSG00000075826.
GeneID	25956.
KEGG	hsa:25956.
UCSC	uc001krc.1. human. uc010qpo.1. human.
Organism-specific databases
CTD	25956.
GeneCards	GC10M102237.
HGNC	HGNC:23197. SEC31B.
HPA	HPA035882. HPA040819.
MIM	610258. gene.
neXtProt	NX_Q9NQW1.
PharmGKB	PA162402792.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG248389.
HOGENOM	HOG000230582.
HOVERGEN	HBG055626.
InParanoid	Q9NQW1.
KO	K14005.
OMA	RLECLYE.
OrthoDB	EOG470TGM.
PhylomeDB	Q9NQW1.
Enzyme and pathway databases
SignaLink	Q9NQW1.
Gene expression databases
ArrayExpress	Q9NQW1.
Bgee	Q9NQW1.
CleanEx	HS_SEC31B.
Genevestigator	Q9NQW1.
Family and domain databases
Gene3D	2.130.10.10. 1 hit.
InterPro	IPR015943. WD40/YVTN_repeat-like_dom. IPR001680. WD40_repeat. IPR019775. WD40_repeat_CS. IPR017986. WD40_repeat_dom. [Graphical view]
Pfam	PF00400. WD40. 2 hits. [Graphical view]
SMART	SM00320. WD40. 5 hits. [Graphical view]
SUPFAM	SSF50978. WD40_like. 1 hit.
PROSITE	PS00678. WD_REPEATS_1. 1 hit. PS50082. WD_REPEATS_2. 1 hit. PS50294. WD_REPEATS_REGION. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	SEC31B. human.
GenomeRNAi	25956.
NextBio	47564.
SOURCE	Search...

Entry information

Entry name

SC31B_HUMAN

Accession

Primary (citable) accession number: Q9NQW1
Secondary accession number(s): B7ZM75 , Q6MZS3, Q86UF0, Q9Y4Q8

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 10, 2007
Last sequence update:	October 1, 2000
Last modified:	May 29, 2013
This is version 92 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.