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Q9NQV6 (PRD10_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 115. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (5) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
PR domain zinc finger protein 10

EC=2.1.1.-
Alternative name(s):
PR domain-containing protein 10
Tristanin
Gene names
Name:PRDM10
Synonyms:KIAA1231, PFM7, TRIS
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length1147 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

May be involved in transcriptional regulation By similarity.

Subcellular location

Nucleus By similarity.

Domain

The SET domain is degenerated, suggesting that it has lost methyltransferase activity.

Sequence similarities

Belongs to the class V-like SAM-binding methyltransferase superfamily.

Contains 10 C2H2-type zinc fingers.

Contains 1 SET domain.

Sequence caution

The sequence BAA91026.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Ontologies

Alternative products

This entry describes 7 isoforms produced by alternative splicing. [Align] [Select]
Isoform 3 (identifier: Q9NQV6-3)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q9NQV6-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-97: MDSKDESSHV...AYVQQDATAQ → MSAYSVPSTFA
     511-514: Missing.
     952-985: Missing.
Isoform 1 (identifier: Q9NQV6-1)

The sequence of this isoform differs from the canonical sequence as follows:
     1-97: MDSKDESSHV...AYVQQDATAQ → MSAYSVPSTFA
Isoform 4 (identifier: Q9NQV6-4)

The sequence of this isoform differs from the canonical sequence as follows:
     511-514: Missing.
     984-984: I → IQVSEPTASAPSSA
Note: No experimental confirmation available.
Isoform 5 (identifier: Q9NQV6-5)

The sequence of this isoform differs from the canonical sequence as follows:
     1-97: MDSKDESSHV...AYVQQDATAQ → MSAYSVPSTFA
     984-984: I → IQVSEPTASAPSSA
Note: No experimental confirmation available.
Isoform 6 (identifier: Q9NQV6-6)

The sequence of this isoform differs from the canonical sequence as follows:
     511-514: Missing.
     984-984: I → IQVSEPTASAPSSA
     1132-1147: TTTNGNGSSEVHITKP → AGSKVIQNEF...IVFKRISKRI
Note: No experimental confirmation available.
Isoform 7 (identifier: Q9NQV6-7)

The sequence of this isoform differs from the canonical sequence as follows:
     984-984: I → IQVSEPTASAPSSA
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 11471147PR domain zinc finger protein 10
PRO_0000047767

Regions

Domain208 – 326119SET
Zinc finger355 – 37723C2H2-type 1
Zinc finger530 – 55223C2H2-type 2
Zinc finger560 – 58223C2H2-type 3
Zinc finger588 – 61023C2H2-type 4
Zinc finger616 – 63924C2H2-type 5
Zinc finger644 – 66623C2H2-type 6
Zinc finger672 – 69524C2H2-type 7
Zinc finger727 – 75024C2H2-type 8
Zinc finger772 – 79524C2H2-type 9
Zinc finger834 – 85724C2H2-type 10
Compositional bias866 – 91651Thr-rich
Compositional bias918 – 1031114Gln-rich
Compositional bias1131 – 11344Poly-Thr

Amino acid modifications

Modified residue4241Phosphoserine Ref.11 Ref.12
Modified residue4281Phosphothreonine Ref.9 Ref.12

Natural variations

Alternative sequence1 – 9797MDSKD…DATAQ → MSAYSVPSTFA in isoform 1, isoform 2 and isoform 5.
VSP_036351
Alternative sequence511 – 5144Missing in isoform 2, isoform 4 and isoform 6.
VSP_035655
Alternative sequence952 – 98534Missing in isoform 2.
VSP_035656
Alternative sequence9841I → IQVSEPTASAPSSA in isoform 4, isoform 5, isoform 6 and isoform 7.
VSP_036352
Alternative sequence1132 – 114716TTTNG…HITKP → AGSKVIQNEFTVGEECELET MTGEKVKTVVQLEGDNKLVT TFKNIKSVTELNGDIITNTM TLGDIVFKRISKRI in isoform 6.
VSP_036353
Natural variant221A → T.
Corresponds to variant rs11221912 [ dbSNP | Ensembl ].
VAR_054418
Natural variant5731T → A. Ref.4 Ref.7 Ref.8
Corresponds to variant rs2241571 [ dbSNP | Ensembl ].
VAR_019984

Experimental info

Sequence conflict461P → S in AAI12935. Ref.6
Sequence conflict3871T → A in BAA91026. Ref.8
Sequence conflict5691F → L in BX648944. Ref.4
Sequence conflict6211C → Y in BX648944. Ref.4
Sequence conflict11121S → N in BX648944. Ref.4

Secondary structure

......................... 1147
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Isoform 3 [UniParc].

Last modified January 9, 2013. Version 3.
Checksum: E565CA8822CB2934

FASTA1,147130,136
        10         20         30         40         50         60 
MDSKDESSHV WPTSAEHEQN AAQVHFVPDT GTVAQIVYTD DQVRPPQQVV YTADGASYTS 

        70         80         90        100        110        120 
VDGPEHTLVY IHPVEAAQTL FTDPGQVAYV QQDATAQQAS LPVHNQVLPS IESVDGSDPL 

       130        140        150        160        170        180 
ATLQTPLGRL EAKEEEDEDE DEDTEEDEEE DGEDTDLDDW EPDPPRPFDP HDLWCEECNN 

       190        200        210        220        230        240 
AHASVCPKHG PLHPIPNRPV LTRARASLPL VLYIDRFLGG VFSKRRIPKR TQFGPVEGPL 

       250        260        270        280        290        300 
VRGSELKDCY IHLKVSLDKG DRKERDLHED LWFELSDETL CNWMMFVRPA QNHLEQNLVA 

       310        320        330        340        350        360 
YQYGHHVYYT TIKNVEPKQE LKVWYAASYA EFVNQKIHDI SEEERKVLRE QEKNWPCYEC 

       370        380        390        400        410        420 
NRRFISSEQL QQHLNSHDEK LDVFSRTRGR GRGRGKRRFG PGRRPGRPPK FIRLEITSEN 

       430        440        450        460        470        480 
GEKSDDGTQD LLHFPTKEQF DEAEPATLNG LDQPEQTTIP IPQLPQETQS SLEHEPETHT 

       490        500        510        520        530        540 
LHLQPQHEES VVPTQSTLTA DDMRRAKRIR LELQNAALQH LFIRKSFRPF KCLQCGKAFR 

       550        560        570        580        590        600 
EKDKLDQHLR FHGREGNCPL TCDLCNKGFI SSTSLESHMK LHSDQKTYSC IFCPESFDRL 

       610        620        630        640        650        660 
DLLKDHVAIH INDGYFTCPT CKKRFPDFIQ VKKHVRSFHS EKIYQCTECD KAFCRPDKLR 

       670        680        690        700        710        720 
LHMLRHSDRK DFLCSTCGKQ FKRKDKLREH MQRMHNPERE AKKADRISRS KTFKPRITST 

       730        740        750        760        770        780 
DYDSFTFKCR LCMMGFRRRG MLVNHLSKRH PDMKIEEVPE LTLPIIKPNR DYFCQYCDKV 

       790        800        810        820        830        840 
YKSASKRKAH ILKNHPGAEL PPSIRKLRPA GPGEPDPMLS THTQLTGTIA TPPVCCPHCS 

       850        860        870        880        890        900 
KQYSSKTKMV QHIRKKHPEF AQLSNTIHTP LTTAVISATP AVLTTDSATG ETVVTTDLLT 

       910        920        930        940        950        960 
QAMTELSQTL TTDYRTPQGD YQRIQYIPVS QSASGLQQPQ HIQLQVVQVA SATSPHQSQQ 

       970        980        990       1000       1010       1020 
STVDVGQLHD PQPYPQHAIQ VQHIQVSGQP LSPSAQQAQQ GLSPSHIQGS SSTQGQALQQ 

      1030       1040       1050       1060       1070       1080 
QQQQQQNSSV QHTYLPSAWN SFRGYSSEIQ MMTLPPGQFV ITDSGVATPV TTGQVKAVTS 

      1090       1100       1110       1120       1130       1140 
GHYVLSESQS ELEEKQTSAL SGGVQVEPPA HSDSLDPQTN SQQQTTQYII TTTTNGNGSS 


EVHITKP 

« Hide

Isoform 2 [UniParc].

Checksum: B5680EAEA32A4299
Show »

FASTA1,023116,444
Isoform 1 [UniParc].

Checksum: C712D4CDA514D995
Show »

FASTA1,061120,711
Isoform 4 [UniParc].

Checksum: 0DF87B79FBAAE62C
Show »

FASTA1,156130,865
Isoform 5 [UniParc].

Checksum: 7F7B76F86712D167
Show »

FASTA1,074121,924
Isoform 6 [UniParc].

Checksum: 05D1A8B9136B7413
Show »

FASTA1,214137,427
Isoform 7 [UniParc].

Checksum: 1CCEC654DC42F464
Show »

FASTA1,160131,349

References

« Hide 'large scale' references
[1]"Ectopic dendrite initiation: CNS pathogenesis as a model of CNS development."
Siegel D.A., Huang M.K., Becker S.F.
Int. J. Dev. Neurosci. 20:373-389(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
Tissue: Brain.
[2]"The yin-yang of PR-domain family genes in tumorigenesis."
Jiang G.L., Huang S.
Histol. Histopathol. 15:109-117(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
[3]"Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
Nagase T., Ishikawa K., Kikuno R., Hirosawa M., Nomura N., Ohara O.
DNA Res. 6:337-345(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
Tissue: Brain.
[4]"The full-ORF clone resource of the German cDNA consortium."
Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I.
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 7), VARIANT ALA-573.
Tissue: Amygdala.
[5]"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G. expand/collapse author list , Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y.
Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[6]Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[7]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 4 AND 5), VARIANT ALA-573.
Tissue: Brain and Uterus.
[8]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 268-1147 (ISOFORM 6), VARIANT ALA-573.
Tissue: Colon mucosa.
[9]"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III, Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N., Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.
Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-428, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Embryonic kidney.
[10]"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Leukemic T-cell.
[11]"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-424, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[12]"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-424 AND THR-428, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[13]"Methyltransferase domain of human PR domain-containing protein 10."
Structural genomics consortium (SGC)
Submitted (JUL-2011) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 188-339.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF503171 mRNA. Translation: AAP30847.1.
AF275817 mRNA. Translation: AAF87243.1.
AB033057 mRNA. Translation: BAA86545.2.
BX648944 mRNA. No translation available.
AP003041 Genomic DNA. No translation available.
AP003326 Genomic DNA. No translation available.
AP003327 Genomic DNA. No translation available.
CH471065 Genomic DNA. Translation: EAW67761.1.
BC112934 mRNA. Translation: AAI12935.1.
BC117415 mRNA. Translation: AAI17416.1.
BC143612 mRNA. Translation: AAI43613.1.
AK000234 mRNA. Translation: BAA91026.1. Different initiation.
CCDSCCDS44771.1. [Q9NQV6-7]
CCDS44772.1. [Q9NQV6-1]
CCDS8484.1. [Q9NQV6-4]
CCDS8485.1. [Q9NQV6-2]
RefSeqNP_064613.2. NM_020228.2. [Q9NQV6-7]
NP_955469.1. NM_199437.1. [Q9NQV6-4]
NP_955470.1. NM_199438.1. [Q9NQV6-1]
NP_955471.1. NM_199439.1. [Q9NQV6-2]
UniGeneHs.275086.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3IHXX-ray2.50A/B/C/D188-339[»]
ProteinModelPortalQ9NQV6.
SMRQ9NQV6. Positions 167-374, 523-825.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid121298. 2 interactions.

PTM databases

PhosphoSiteQ9NQV6.

Polymorphism databases

DMDM442570289.

Proteomic databases

MaxQBQ9NQV6.
PaxDbQ9NQV6.
PRIDEQ9NQV6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000304538; ENSP00000302669; ENSG00000170325. [Q9NQV6-2]
ENST00000358825; ENSP00000351686; ENSG00000170325. [Q9NQV6-7]
ENST00000360871; ENSP00000354118; ENSG00000170325. [Q9NQV6-4]
ENST00000423662; ENSP00000398431; ENSG00000170325. [Q9NQV6-1]
ENST00000526082; ENSP00000432237; ENSG00000170325. [Q9NQV6-5]
GeneID56980.
KEGGhsa:56980.
UCSCuc001qfj.3. human. [Q9NQV6-1]
uc001qfk.3. human. [Q9NQV6-2]
uc001qfl.3. human. [Q9NQV6-5]
uc001qfn.3. human.

Organism-specific databases

CTD56980.
GeneCardsGC11M129803.
HGNCHGNC:13995. PRDM10.
HPAHPA026997.
neXtProtNX_Q9NQV6.
PharmGKBPA33708.
HUGESearch...
GenAtlasSearch...

Phylogenomic databases

eggNOGCOG5048.
HOVERGENHBG053664.
InParanoidQ9NQV6.
OMAHDPQTYT.
OrthoDBEOG70GMFD.
TreeFamTF350894.

Enzyme and pathway databases

SignaLinkQ9NQV6.

Gene expression databases

ArrayExpressQ9NQV6.
BgeeQ9NQV6.
CleanExHS_PRDM10.
GenevestigatorQ9NQV6.

Family and domain databases

Gene3D3.30.160.60. 5 hits.
InterProIPR001214. SET_dom.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
IPR022755. Znf_C2H2_jaz.
[Graphical view]
PfamPF00096. zf-C2H2. 4 hits.
PF12171. zf-C2H2_jaz. 1 hit.
[Graphical view]
SMARTSM00355. ZnF_C2H2. 10 hits.
[Graphical view]
PROSITEPS50280. SET. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 10 hits.
PS50157. ZINC_FINGER_C2H2_2. 10 hits.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSPRDM10. human.
EvolutionaryTraceQ9NQV6.
GenomeRNAi56980.
NextBio35535048.
PROQ9NQV6.

Entry information

Entry namePRD10_HUMAN
AccessionPrimary (citable) accession number: Q9NQV6
Secondary accession number(s): B7ZL71 expand/collapse secondary AC list , G3XAE5, J3KP23, Q17R90, Q2KHR4, Q863Z2, Q9NXI4, Q9ULI9
Entry history
Integrated into UniProtKB/Swiss-Prot: November 16, 2001
Last sequence update: January 9, 2013
Last modified: July 9, 2014
This is version 115 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 11

Human chromosome 11: entries, gene names and cross-references to MIM