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Q9NQG7

- HPS4_HUMAN

UniProt

Q9NQG7 - HPS4_HUMAN

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Protein

Hermansky-Pudlak syndrome 4 protein

Gene
HPS4, KIAA1667
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

May function in the pathway of organelle biogenesis.

GO - Molecular functioni

  1. protein binding Source: IntAct
  2. protein dimerization activity Source: UniProtKB
  3. protein homodimerization activity Source: UniProtKB

GO - Biological processi

  1. blood coagulation Source: Ensembl
  2. hemostasis Source: UniProtKB
  3. lysosome organization Source: UniProtKB
  4. melanocyte differentiation Source: Ensembl
  5. positive regulation of eye pigmentation Source: UniProtKB
  6. protein stabilization Source: UniProtKB
  7. protein targeting Source: UniProtKB
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Hermansky-Pudlak syndrome 4 protein
Alternative name(s):
Light-ear protein homolog
Gene namesi
Name:HPS4
Synonyms:KIAA1667
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 22

Organism-specific databases

HGNCiHGNC:15844. HPS4.

Subcellular locationi

GO - Cellular componenti

  1. BLOC-3 complex Source: FlyBase
  2. cytoplasm Source: UniProtKB
  3. lysosome Source: UniProtKB
  4. melanosome Source: UniProtKB
  5. membrane Source: UniProtKB
  6. platelet dense granule Source: UniProtKB
Complete GO annotation...

Pathology & Biotechi

Involvement in diseasei

Hermansky-Pudlak syndrome 4 (HPS4) [MIM:614073]: A form of Hermansky-Pudlak syndrome, a genetically heterogeneous autosomal recessive disorder characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS.
Note: The disease is caused by mutations affecting the gene represented in this entry.1 Publication

Keywords - Diseasei

Albinism, Hermansky-Pudlak syndrome

Organism-specific databases

MIMi614073. phenotype.
Orphaneti231500. Hermansky-Pudlak syndrome with pulmonary fibrosis.
PharmGKBiPA29434.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 708708Hermansky-Pudlak syndrome 4 proteinPRO_0000084052Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei355 – 3551Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9NQG7.
PaxDbiQ9NQG7.
PRIDEiQ9NQG7.

PTM databases

PhosphoSiteiQ9NQG7.

Expressioni

Gene expression databases

ArrayExpressiQ9NQG7.
BgeeiQ9NQG7.
CleanExiHS_HPS4.
GenevestigatoriQ9NQG7.

Organism-specific databases

HPAiCAB033106.
HPA050189.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
HPS1Q9290215EBI-704377,EBI-704347

Protein-protein interaction databases

BioGridi124600. 1 interaction.
IntActiQ9NQG7. 2 interactions.
STRINGi9606.ENSP00000338457.

Structurei

3D structure databases

ProteinModelPortaliQ9NQG7.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG85637.
HOVERGENiHBG031612.
OMAiAVYACCN.
OrthoDBiEOG7XWPQZ.
PhylomeDBiQ9NQG7.
TreeFamiTF332819.

Family and domain databases

InterProiIPR026091. HPS4.
[Graphical view]
PANTHERiPTHR14407. PTHR14407. 1 hit.

Sequences (4)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9NQG7-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MATSTSTEAK SASWWNYFFL YDGSKVKEEG DPTRAGICYF YPSQTLLDQQ    50
ELLCGQIAGV VRCVSDISDS PPTLVRLRKL KFAIKVDGDY LWVLGCAVEL 100
PDVSCKRFLD QLVGFFNFYN GPVSLAYENC SQEELSTEWD TFIEQILKNT 150
SDLHKIFNSL WNLDQTKVEP LLLLKAARIL QTCQRSPHIL AGCILYKGLI 200
VSTQLPPSLT AKVLLHRTAP QEQRLPTGED APQEHGAALP PNVQIIPVFV 250
TKEEAISLHE FPVEQMTRSL ASPAGLQDGS AQHHPKGGST SALKENATGH 300
VESMAWTTPD PTSPDEACPD GRKENGCLSG HDLESIRPAG LHNSARGEVL 350
GLSSSLGKEL VFLQEELDLS EIHIPEAQEV EMASGHFAFL HVPVPDGRAP 400
YCKASLSASS SLEPTPPEDT AISSLRPPSA PEMLTQHGAQ EQLEDHPGHS 450
SQAPIPRADP LPRRTRRPLL LPRLDPGQRG NKLPTGEQGL DEDVDGVCES 500
HAAPGLECSS GSANCQGAGP SADGISSRLT PAESCMGLVR MNLYTHCVKG 550
LVLSLLAEEP LLGDSAAIEE VYHSSLASLN GLEVHLKETL PRDEAASTSS 600
TYNFTHYDRI QSLLMANLPQ VATPQDRRFL QAVSLMHSEF AQLPALYEMT 650
VRNASTAVYA CCNPIQETYF QQLAPAARSS GFPNPQDGAF SLSGKAKQKL 700
LKHGVNLL 708
Length:708
Mass (Da):76,919
Last modified:June 6, 2002 - v2
Checksum:iE47BCF49FC78830A
GO
Isoform 2 (identifier: Q9NQG7-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     236-236: G → GKWMLWSFKNRVTHQNPNG
     463-510: RRTRRPLLLP...HAAPGLECSS → KSTVLFSGGC...FFDSMRQTAG
     511-708: Missing.

Note: No experimental confirmation available.

Show »
Length:528
Mass (Da):58,067
Checksum:i59CCB0697F2192EA
GO
Isoform 3 (identifier: Q9NQG7-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-14: MATSTSTEAKSASW → MAPLCSLAR

Note: No experimental confirmation available.

Show »
Length:703
Mass (Da):76,423
Checksum:iC73D3EE841604112
GO
Isoform 4 (identifier: Q9NQG7-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-14: MATSTSTEAKSASW → MAPLCSLAR
     236-236: G → GKWMLWSFKNRVTHQNPNG

Note: No experimental confirmation available.

Show »
Length:721
Mass (Da):78,648
Checksum:i60F5499DBDBAF003
GO

Sequence cautioni

The sequence BAB33337.1 differs from that shown. Reason: Intron retention.
The sequence BC035614 differs from that shown. Reason: Intron retention.
The sequence BAB33337.1 differs from that shown. Reason: Frameshift at position 237.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti229 – 2291E → G.3 Publications
Corresponds to variant rs713998 [ dbSNP | Ensembl ].
VAR_025006
Natural varianti443 – 4431L → V.1 Publication
Corresponds to variant rs2014410 [ dbSNP | Ensembl ].
VAR_024158
Natural varianti552 – 5521V → M.3 Publications
Corresponds to variant rs5752330 [ dbSNP | Ensembl ].
VAR_025007
Natural varianti606 – 6061H → Y.3 Publications
Corresponds to variant rs1894706 [ dbSNP | Ensembl ].
VAR_024159
Natural varianti625 – 6251Q → H.2 Publications
Corresponds to variant rs1894704 [ dbSNP | Ensembl ].
VAR_021836

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 1414MATST…KSASW → MAPLCSLAR in isoform 3 and isoform 4. VSP_017082Add
BLAST
Alternative sequencei236 – 2361G → GKWMLWSFKNRVTHQNPNG in isoform 2 and isoform 4. VSP_003880
Alternative sequencei463 – 51048RRTRR…LECSS → KSTVLFSGGCVKGSDTQLCV PGLVWYLEPQFYYVIVRHFF DSMRQTAG in isoform 2. VSP_003881Add
BLAST
Alternative sequencei511 – 708198Missing in isoform 2. VSP_003882Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti168 – 1681V → A1 Publication
Sequence conflicti430 – 4301A → V in BAB71540. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY043416 mRNA. Translation: AAK95330.1.
AL365512 mRNA. Translation: CAB97208.1.
AK057648 mRNA. Translation: BAB71540.1.
AL713795 mRNA. Translation: CAD28549.1.
Z99714 Genomic DNA. Translation: CAI17880.1.
Z99714 Genomic DNA. Translation: CAQ09361.1.
BC035614 mRNA. No translation available.
AB051454 mRNA. Translation: BAB33337.1. Sequence problems.
CCDSiCCDS13835.1. [Q9NQG7-1]
CCDS46677.1. [Q9NQG7-3]
RefSeqiNP_071364.4. NM_022081.5. [Q9NQG7-1]
NP_690054.1. NM_152841.2. [Q9NQG7-3]
UniGeneiHs.474436.

Genome annotation databases

EnsembliENST00000336873; ENSP00000338457; ENSG00000100099. [Q9NQG7-1]
ENST00000398141; ENSP00000381210; ENSG00000100099. [Q9NQG7-4]
ENST00000398145; ENSP00000381213; ENSG00000100099. [Q9NQG7-1]
ENST00000402105; ENSP00000384185; ENSG00000100099. [Q9NQG7-3]
GeneIDi89781.
KEGGihsa:89781.
UCSCiuc003ach.4. human. [Q9NQG7-1]
uc003aci.4. human. [Q9NQG7-3]
uc003acj.4. human. [Q9NQG7-4]

Polymorphism databases

DMDMi21362617.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Web resourcesi

Mutations of the HPS4 gene

Retina International's Scientific Newsletter

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY043416 mRNA. Translation: AAK95330.1 .
AL365512 mRNA. Translation: CAB97208.1 .
AK057648 mRNA. Translation: BAB71540.1 .
AL713795 mRNA. Translation: CAD28549.1 .
Z99714 Genomic DNA. Translation: CAI17880.1 .
Z99714 Genomic DNA. Translation: CAQ09361.1 .
BC035614 mRNA. No translation available.
AB051454 mRNA. Translation: BAB33337.1 . Sequence problems.
CCDSi CCDS13835.1. [Q9NQG7-1 ]
CCDS46677.1. [Q9NQG7-3 ]
RefSeqi NP_071364.4. NM_022081.5. [Q9NQG7-1 ]
NP_690054.1. NM_152841.2. [Q9NQG7-3 ]
UniGenei Hs.474436.

3D structure databases

ProteinModelPortali Q9NQG7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 124600. 1 interaction.
IntActi Q9NQG7. 2 interactions.
STRINGi 9606.ENSP00000338457.

PTM databases

PhosphoSitei Q9NQG7.

Polymorphism databases

DMDMi 21362617.

Proteomic databases

MaxQBi Q9NQG7.
PaxDbi Q9NQG7.
PRIDEi Q9NQG7.

Protocols and materials databases

DNASUi 89781.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000336873 ; ENSP00000338457 ; ENSG00000100099 . [Q9NQG7-1 ]
ENST00000398141 ; ENSP00000381210 ; ENSG00000100099 . [Q9NQG7-4 ]
ENST00000398145 ; ENSP00000381213 ; ENSG00000100099 . [Q9NQG7-1 ]
ENST00000402105 ; ENSP00000384185 ; ENSG00000100099 . [Q9NQG7-3 ]
GeneIDi 89781.
KEGGi hsa:89781.
UCSCi uc003ach.4. human. [Q9NQG7-1 ]
uc003aci.4. human. [Q9NQG7-3 ]
uc003acj.4. human. [Q9NQG7-4 ]

Organism-specific databases

CTDi 89781.
GeneCardsi GC22M026840.
GeneReviewsi HPS4.
HGNCi HGNC:15844. HPS4.
HPAi CAB033106.
HPA050189.
MIMi 606682. gene.
614073. phenotype.
neXtProti NX_Q9NQG7.
Orphaneti 231500. Hermansky-Pudlak syndrome with pulmonary fibrosis.
PharmGKBi PA29434.
HUGEi Search...
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG85637.
HOVERGENi HBG031612.
OMAi AVYACCN.
OrthoDBi EOG7XWPQZ.
PhylomeDBi Q9NQG7.
TreeFami TF332819.

Miscellaneous databases

GeneWikii HPS4.
GenomeRNAii 89781.
NextBioi 76267.
PROi Q9NQG7.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q9NQG7.
Bgeei Q9NQG7.
CleanExi HS_HPS4.
Genevestigatori Q9NQG7.

Family and domain databases

InterProi IPR026091. HPS4.
[Graphical view ]
PANTHERi PTHR14407. PTHR14407. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Hermansky-Pudlak syndrome is caused by mutations in HPS4, the human homolog of the mouse light-ear gene."
    Suzuki T., Li W., Zhang Q., Karim A., Novak E.K., Sviderskaya E.V., Hill S.P., Bennett D.C., Levin A.V., Nieuwenhuis H.K., Fong C.-T., Castellan C., Miterski B., Swank R.T., Spritz R.A.
    Nat. Genet. 30:321-324(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), INVOLVEMENT IN HPS4.
  2. "Reevaluating human gene annotation: a second-generation analysis of chromosome 22."
    Collins J.E., Goward M.E., Cole C.G., Smink L.J., Huckle E.J., Knowles S., Bye J.M., Beare D.M., Dunham I.
    Genome Res. 13:27-36(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), VARIANT GLY-229.
    Tissue: Trachea.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANTS GLY-229; VAL-443; MET-552; TYR-606 AND HIS-625.
    Tissue: Testis.
  5. "The DNA sequence of human chromosome 22."
    Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., Clamp M., Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., Bagguley C., Bailey J., Barlow K.F., Bates K.N., Beasley O.P., Bird C.P., Blakey S.E., Bridgeman A.M.
    , Buck D., Burgess J., Burrill W.D., Burton J., Carder C., Carter N.P., Chen Y., Clark G., Clegg S.M., Cobley V.E., Cole C.G., Collier R.E., Connor R., Conroy D., Corby N.R., Coville G.J., Cox A.V., Davis J., Dawson E., Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M., Ellington A.G., Evans K.L., Fey J.M., Fleming K., French L., Garner A.A., Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C., Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., Hunt S.E., Jones M.C., Kershaw J., Kimberley A.M., King A., Laird G.K., Langford C.F., Leversha M.A., Lloyd C., Lloyd D.M., Martyn I.D., Mashreghi-Mohammadi M., Matthews L.H., Mccann O.T., Mcclay J., Mclaren S., McMurray A.A., Milne S.A., Mortimore B.J., Odell C.N., Pavitt R., Pearce A.V., Pearson D., Phillimore B.J.C.T., Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y., Rogers L., Ross M.T., Scott C.E., Sehra H.K., Skuce C.D., Smalley S., Smith M.L., Soderlund C., Spragon L., Steward C.A., Sulston J.E., Swann R.M., Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L., Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L., Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N., Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., Shintani A., Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., Roe B.A., Chen F., Chu L., Crabtree J., Deschamps S., Do A., Do T., Dorman A., Fang F., Fu Y., Hu P., Hua A., Kenton S., Lai H., Lao H.I., Lewis J., Lewis S., Lin S.-P., Loh P., Malaj E., Nguyen T., Pan H., Phan S., Qi S., Qian Y., Ray L., Ren Q., Shaull S., Sloan D., Song L., Wang Q., Wang Y., Wang Z., White J., Willingham D., Wu H., Yao Z., Zhan M., Zhang G., Chissoe S., Murray J., Miller N., Minx P., Fulton R., Johnson D., Bemis G., Bentley D., Bradshaw H., Bourne S., Cordes M., Du Z., Fulton L., Goela D., Graves T., Hawkins J., Hinds K., Kemp K., Latreille P., Layman D., Ozersky P., Rohlfing T., Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K., Nelson J., Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R., Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., Budarf M.L., McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., Edelmann L., Kim U.J., Shizuya H., Simon M.I., Dumanski J.P., Peyrard M., Kedra D., Seroussi E., Fransson I., Tapia I., Bruder C.E., O'Brien K.P., Wilkinson P., Bodenteich A., Hartman K., Hu X., Khan A.S., Lane L., Tilahun Y., Wright H.
    Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4), VARIANTS GLY-229; MET-552 AND TYR-606.
    Tissue: Testis.
  7. "Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping."
    Hirosawa M., Nagase T., Murahashi Y., Kikuno R., Ohara O.
    DNA Res. 8:1-9(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 204-708 (ISOFORM 1), VARIANTS MET-552; TYR-606 AND HIS-625.
    Tissue: Brain.
  8. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Platelet.
  9. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-355, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.

Entry informationi

Entry nameiHPS4_HUMAN
AccessioniPrimary (citable) accession number: Q9NQG7
Secondary accession number(s): B1AHQ4
, Q5H8V6, Q96LX6, Q9BY93, Q9UH37, Q9UH38
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 6, 2002
Last sequence update: June 6, 2002
Last modified: July 9, 2014
This is version 116 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

External Data

Dasty 3

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