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Protein

Nuclear receptor-interacting protein 3

Gene

NRIP3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Protein family/group databases

MEROPSiA28.002.

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear receptor-interacting protein 3
Alternative name(s):
Sarcoma antigen NY-SAR-105
Gene namesi
Name:NRIP3
Synonyms:C11orf14
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:1167. NRIP3.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25481.

Polymorphism and mutation databases

BioMutaiNRIP3.
DMDMi34395556.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 241241Nuclear receptor-interacting protein 3PRO_0000057953Add
BLAST

Proteomic databases

EPDiQ9NQ35.
MaxQBiQ9NQ35.
PaxDbiQ9NQ35.
PeptideAtlasiQ9NQ35.
PRIDEiQ9NQ35.

PTM databases

iPTMnetiQ9NQ35.
PhosphoSiteiQ9NQ35.
UniCarbKBiQ9NQ35.

Expressioni

Gene expression databases

BgeeiQ9NQ35.
CleanExiHS_NRIP3.
ExpressionAtlasiQ9NQ35. baseline and differential.
GenevisibleiQ9NQ35. HS.

Organism-specific databases

HPAiHPA040573.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CCDC155Q8N6L03EBI-10311735,EBI-749265

Protein-protein interaction databases

BioGridi121183. 6 interactions.
IntActiQ9NQ35. 1 interaction.
STRINGi9606.ENSP00000310205.

Structurei

3D structure databases

ProteinModelPortaliQ9NQ35.
SMRiQ9NQ35. Positions 107-220.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0012. Eukaryota.
ENOG410XPA0. LUCA.
GeneTreeiENSGT00510000046989.
HOGENOMiHOG000236257.
HOVERGENiHBG052668.
InParanoidiQ9NQ35.
OMAiVKSHKHE.
OrthoDBiEOG70ZZPQ.
PhylomeDBiQ9NQ35.
TreeFamiTF333421.

Family and domain databases

InterProiIPR019103. Peptidase_aspartic_DDI1-type.
IPR021109. Peptidase_aspartic_dom.
[Graphical view]
PfamiPF09668. Asp_protease. 1 hit.
[Graphical view]
SUPFAMiSSF50630. SSF50630. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9NQ35-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFYSGLLTEG GRKETDMREA ASLRQQRRMK QAVQFIHKDS ADLLPLDGLK
60 70 80 90 100
KLGSSKDMQP HNILQRRLME TNLSKLRSGP RVPWASKTNK LNQAKSEGLK
110 120 130 140 150
KSEEDDMILV SCQCAGKDVK ALVDTGCLYN LISLACVDRL GLKEHVKSHK
160 170 180 190 200
HEGEKLSLPR HLKVVGQIEH LVITLGSLRL DCPAAVVDDN EKNLSLGLQT
210 220 230 240
LRSLKCIINL DKHRLIMGKT DKEEIPFVET VSLNEDNTSE A
Length:241
Mass (Da):26,975
Last modified:October 1, 2000 - v1
Checksum:i3ECFE6A3CE3DB539
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ400877 Genomic DNA. Translation: CAB92286.1.
AK024750 mRNA. Translation: BAB14984.1.
BC008835 mRNA. Translation: AAH08835.1.
AY211930 mRNA. Translation: AAO65183.1.
CCDSiCCDS31422.1.
RefSeqiNP_065696.1. NM_020645.2.
UniGeneiHs.523467.

Genome annotation databases

EnsembliENST00000309166; ENSP00000310205; ENSG00000175352.
GeneIDi56675.
KEGGihsa:56675.
UCSCiuc001mhg.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ400877 Genomic DNA. Translation: CAB92286.1.
AK024750 mRNA. Translation: BAB14984.1.
BC008835 mRNA. Translation: AAH08835.1.
AY211930 mRNA. Translation: AAO65183.1.
CCDSiCCDS31422.1.
RefSeqiNP_065696.1. NM_020645.2.
UniGeneiHs.523467.

3D structure databases

ProteinModelPortaliQ9NQ35.
SMRiQ9NQ35. Positions 107-220.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi121183. 6 interactions.
IntActiQ9NQ35. 1 interaction.
STRINGi9606.ENSP00000310205.

Protein family/group databases

MEROPSiA28.002.

PTM databases

iPTMnetiQ9NQ35.
PhosphoSiteiQ9NQ35.
UniCarbKBiQ9NQ35.

Polymorphism and mutation databases

BioMutaiNRIP3.
DMDMi34395556.

Proteomic databases

EPDiQ9NQ35.
MaxQBiQ9NQ35.
PaxDbiQ9NQ35.
PeptideAtlasiQ9NQ35.
PRIDEiQ9NQ35.

Protocols and materials databases

DNASUi56675.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000309166; ENSP00000310205; ENSG00000175352.
GeneIDi56675.
KEGGihsa:56675.
UCSCiuc001mhg.2. human.

Organism-specific databases

CTDi56675.
GeneCardsiNRIP3.
HGNCiHGNC:1167. NRIP3.
HPAiHPA040573.
MIMi613125. gene.
neXtProtiNX_Q9NQ35.
PharmGKBiPA25481.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0012. Eukaryota.
ENOG410XPA0. LUCA.
GeneTreeiENSGT00510000046989.
HOGENOMiHOG000236257.
HOVERGENiHBG052668.
InParanoidiQ9NQ35.
OMAiVKSHKHE.
OrthoDBiEOG70ZZPQ.
PhylomeDBiQ9NQ35.
TreeFamiTF333421.

Miscellaneous databases

ChiTaRSiNRIP3. human.
GenomeRNAii56675.
PROiQ9NQ35.
SOURCEiSearch...

Gene expression databases

BgeeiQ9NQ35.
CleanExiHS_NRIP3.
ExpressionAtlasiQ9NQ35. baseline and differential.
GenevisibleiQ9NQ35. HS.

Family and domain databases

InterProiIPR019103. Peptidase_aspartic_DDI1-type.
IPR021109. Peptidase_aspartic_dom.
[Graphical view]
PfamiPF09668. Asp_protease. 1 hit.
[Graphical view]
SUPFAMiSSF50630. SSF50630. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Comparative genomic sequencing reveals a strikingly similar architecture of a conserved syntenic region on human chromosome 11p15.3 (including gene ST5) and mouse chromosome 7."
    Amid C., Bahr A., Mujica A., Sampson N., Bikar S.E., Winterpacht A., Zabel B., Hankeln T., Schmidt E.R.
    Cytogenet. Cell Genet. 93:284-290(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Uterus.
  4. Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 64-241.

Entry informationi

Entry nameiNRIP3_HUMAN
AccessioniPrimary (citable) accession number: Q9NQ35
Secondary accession number(s): Q86WD9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 29, 2003
Last sequence update: October 1, 2000
Last modified: July 6, 2016
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.