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Q9NQ34 (TMM9B_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Transmembrane protein 9B
Gene names
Name:TMEM9B
Synonyms:C11orf15
ORF Names:UNQ712/PRO1375
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length198 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Membrane; Single-pass membrane protein Potential.

Sequence similarities

Belongs to the TMEM9 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3333 Ref.4
Chain34 – 198165Transmembrane protein 9B
PRO_0000034376

Regions

Transmembrane103 – 12523Helical; Potential

Amino acid modifications

Modified residue1641Phosphoserine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9NQ34 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 888E55365A01B44F

FASTA19822,531
        10         20         30         40         50         60 
MATLWGGLLR LGSLLSLSCL ALSVLLLAQL SDAAKNFEDV RCKCICPPYK ENSGHIYNKN 

        70         80         90        100        110        120 
ISQKDCDCLH VVEPMPVRGP DVEAYCLRCE CKYEERSSVT IKVTIIIYLS ILGLLLLYMV 

       130        140        150        160        170        180 
YLTLVEPILK RRLFGHAQLI QSDDDIGDHQ PFANAHDVLA RSRSRANVLN KVEYAQQRWK 

       190 
LQVQEQRKSV FDRHVVLS 

« Hide

References

« Hide 'large scale' references
[1]"Comparative genomic sequencing reveals a strikingly similar architecture of a conserved syntenic region on human chromosome 11p15.3 (including gene ST5) and mouse chromosome 7."
Amid C., Bahr A., Mujica A., Sampson N., Bikar S.E., Winterpacht A., Zabel B., Hankeln T., Schmidt E.R.
Cytogenet. Cell Genet. 93:284-290(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J., Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P., Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E. expand/collapse author list , Heldens S., Huang A., Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D., Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L., Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C., Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J., Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M.
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Pancreas.
[4]"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Zhang Z., Henzel W.J.
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 34-48.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ400877 Genomic DNA. Translation: CAB92287.1.
AY359069 mRNA. Translation: AAQ89428.1.
BC040124 mRNA. Translation: AAH40124.1.
IPIIPI00009880.
RefSeqNP_065695.1. NM_020644.1.
UniGeneHs.501853.

3D structure databases

ProteinModelPortalQ9NQ34.
ModBaseSearch...

Protein-protein interaction databases

IntActQ9NQ34. 1 interaction.
MINTMINT-1390777.

PTM databases

PhosphoSiteQ9NQ34.

Polymorphism databases

DMDM20532029.

Proteomic databases

PaxDbQ9NQ34.
PeptideAtlasQ9NQ34.
PRIDEQ9NQ34.

Protocols and materials databases

DNASU56674.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000534025; ENSP00000433361; ENSG00000175348.
GeneID56674.
KEGGhsa:56674.
UCSCuc001mhe.1. human.

Organism-specific databases

CTD56674.
GeneCardsGC11M008969.
HGNCHGNC:1168. TMEM9B.
HPAHPA037784.
neXtProtNX_Q9NQ34.
PharmGKBPA25482.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG289024.
HOGENOMHOG000044306.
HOVERGENHBG050972.
InParanoidQ9NQ34.
OMAMLNKVEH.
OrthoDBEOG45HRZP.
PhylomeDBQ9NQ34.

Gene expression databases

ArrayExpressQ9NQ34.
BgeeQ9NQ34.
CleanExHS_TMEM9B.
GenevestigatorQ9NQ34.
GermOnlineENSG00000175348. Homo sapiens.

Family and domain databases

InterProIPR008853. TMEM9.
[Graphical view]
PANTHERPTHR13064. PTHR13064. 1 hit.
PfamPF05434. Tmemb_9. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSTMEM9B. human.
GenomeRNAi56674.
NextBio62173.

Entry information

Entry nameTMM9B_HUMAN
AccessionPrimary (citable) accession number: Q9NQ34
Entry history
Integrated into UniProtKB/Swiss-Prot: May 10, 2002
Last sequence update: October 1, 2000
Last modified: April 3, 2013
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 11

Human chromosome 11: entries, gene names and cross-references to MIM

SIMILARITY comments

Index of protein domains and families