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Q9NQ25 (SLAF7_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 117. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (6) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
SLAM family member 7
Alternative name(s):
CD2 subset 1
CD2-like receptor-activating cytotoxic cells
Short name=CRACC
Membrane protein FOAP-12
Novel Ly9
Protein 19A
CD_antigen=CD319
Gene names
Name:SLAMF7
Synonyms:CS1
ORF Names:UNQ576/PRO1138
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length335 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Isoform 1 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Ref.2 Ref.3

Isoform 3 does not mediate any NK cell activation. Ref.2 Ref.3

Subunit structure

Isoform 1 binds to SH2D1A when its cytoplasmic tail is phosphorylated in the presence of FYN (in vitro).

Subcellular location

Membrane; Single-pass type I membrane protein.

Tissue specificity

Expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. Isoform 3 is expressed at much lower level than isoform 1. Ref.1 Ref.2 Ref.3 Ref.13

Sequence similarities

Contains 1 Ig-like C2-type (immunoglobulin-like) domain.

Sequence caution

The sequence CAB76561.1 differs from that shown. Reason: Frameshift at several positions.

Alternative products

This entry describes 7 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q9NQ25-1)

Also known as: 19A; CS1-L;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q9NQ25-2)

The sequence of this isoform differs from the canonical sequence as follows:
     19-125: Missing.
Note: No experimental confirmation available.
Isoform 3 (identifier: Q9NQ25-3)

Also known as: 19A24; CS1-S;

The sequence of this isoform differs from the canonical sequence as follows:
     258-296: YIEEKKRVDI...IPHTNRTILK → NNPKGRSSKY...DARHTKAICL
Isoform 4 (identifier: Q9NQ25-4)

The sequence of this isoform differs from the canonical sequence as follows:
     127-165: HLSKPKVTMG...GEEDVIYTWK → NNPKGRSSKY...DARHTKAICL
     166-335: Missing.
Note: No experimental confirmation available.
Isoform 5 (identifier: Q9NQ25-5)

The sequence of this isoform differs from the canonical sequence as follows:
     258-335: YIEEKKRVDI...PRLFAYENVI → NNPKGRSSKY...DARHTKAICL
Note: No experimental confirmation available.
Isoform 6 (identifier: Q9NQ25-6)

The sequence of this isoform differs from the canonical sequence as follows:
     126-256: Missing.
Note: No experimental confirmation available.
Isoform 7 (identifier: Q9NQ25-7)

The sequence of this isoform differs from the canonical sequence as follows:
     19-125: Missing.
     217-256: Missing.
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 Ref.11
Chain23 – 335313SLAM family member 7
PRO_0000014963

Regions

Topological domain23 – 226204Extracellular Potential
Transmembrane227 – 24721Helical; Potential
Topological domain248 – 33588Cytoplasmic Potential
Domain131 – 20676Ig-like C2-type

Amino acid modifications

Glycosylation981N-linked (GlcNAc...) Potential
Glycosylation1421N-linked (GlcNAc...) Potential
Glycosylation1481N-linked (GlcNAc...) Potential
Glycosylation1721N-linked (GlcNAc...) Potential
Glycosylation1761N-linked (GlcNAc...) Potential
Glycosylation2041N-linked (GlcNAc...) Potential
Disulfide bond145 ↔ 215 Potential
Disulfide bond151 ↔ 195 By similarity

Natural variations

Alternative sequence19 – 125107Missing in isoform 2 and isoform 7.
VSP_013781
Alternative sequence126 – 256131Missing in isoform 6.
VSP_055292
Alternative sequence127 – 16539HLSKP…IYTWK → NNPKGRSSKYGLLHCGNTEK DGKSPLTAHDARHTKAICL in isoform 4.
VSP_054540
Alternative sequence166 – 335170Missing in isoform 4.
VSP_054541
Alternative sequence217 – 25640Missing in isoform 7.
VSP_055293
Alternative sequence258 – 33578YIEEK…YENVI → NNPKGRSSKYGLLHCGNTEK DGKSPLTAHDARHTKAICL in isoform 5.
VSP_054542
Alternative sequence258 – 29639YIEEK…RTILK → NNPKGRSSKYGLLHCGNTEK DGKSPLTAHDARHTKAICL in isoform 3.
VSP_013782
Natural variant1751H → Y.
Corresponds to variant rs35325048 [ dbSNP | Ensembl ].
VAR_049938
Natural variant3021T → M.
Corresponds to variant rs2295617 [ dbSNP | Ensembl ].
VAR_049939

Experimental info

Sequence conflict1351M → L in CAB81950. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 (19A) (CS1-L) [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: D09ABBCFF74BE8D4

FASTA33537,421
        10         20         30         40         50         60 
MAGSPTCLTL IYILWQLTGS AASGPVKELV GSVGGAVTFP LKSKVKQVDS IVWTFNTTPL 

        70         80         90        100        110        120 
VTIQPEGGTI IVTQNRNRER VDFPDGGYSL KLSKLKKNDS GIYYVGIYSS SLQQPSTQEY 

       130        140        150        160        170        180 
VLHVYEHLSK PKVTMGLQSN KNGTCVTNLT CCMEHGEEDV IYTWKALGQA ANESHNGSIL 

       190        200        210        220        230        240 
PISWRWGESD MTFICVARNP VSRNFSSPIL ARKLCEGAAD DPDSSMVLLC LLLVPLLLSL 

       250        260        270        280        290        300 
FVLGLFLWFL KRERQEEYIE EKKRVDICRE TPNICPHSGE NTEYDTIPHT NRTILKEDPA 

       310        320        330 
NTVYSTVEIP KKMENPHSLL TMPDTPRLFA YENVI 

« Hide

Isoform 2 [UniParc].

Checksum: 2B01DB70E7BBFC14
Show »

FASTA22825,831
Isoform 3 (19A24) (CS1-S) [UniParc].

Checksum: 3CD49C30FF3367B0
Show »

FASTA33537,026
Isoform 4 [UniParc].

Checksum: E70079B2E27C5978
Show »

FASTA16517,945
Isoform 5 [UniParc].

Checksum: E85D277192494EEC
Show »

FASTA29632,581
Isoform 6 [UniParc].

Checksum: E7DEE14130014CD5
Show »

FASTA20422,785
Isoform 7 [UniParc].

Checksum: 76BA8CF2C70B4663
Show »

FASTA18821,316

References

« Hide 'large scale' references
[1]"Molecular cloning of CS1, a novel human natural killer cell receptor belonging to the CD2 subset of the immunoglobulin superfamily."
Boles K.S., Mathew P.A.
Immunogenetics 52:302-307(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY.
[2]"Activation of NK cell-mediated cytotoxicity by a SAP-independent receptor of the CD2 family."
Bouchon A., Cella M., Grierson H.L., Cohen J.I., Colonna M.
J. Immunol. 167:5517-5521(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, TISSUE SPECIFICITY.
[3]"A novel immunoglobulin superfamily receptor (19A) related to CD2 is expressed on activated lymphocytes and promotes homotypic B-cell adhesion."
Murphy J.J., Hobby P., Vilarino-Varela J., Bishop B., Iordanidou P., Sutton B.J., Norton J.D.
Biochem. J. 361:431-436(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 3), FUNCTION, TISSUE SPECIFICITY.
[4]"Homo sapiens mRNA for FOAP-12 protein, complete cds."
Fujii Y., Takayama K., Tsuritani K., Yajima Y., Amemiya T., Ukai Y., Naito K., Kawaguchi A.
Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
Tissue: Macrophage.
[5]"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J., Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P., Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E. expand/collapse author list , Heldens S., Huang A., Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D., Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L., Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C., Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J., Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M.
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[6]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 4; 6 AND 7).
Tissue: Lung and Synovium.
[7]"The full-ORF clone resource of the German cDNA consortium."
Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I.
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
Tissue: Lymph node.
[8]"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. expand/collapse author list , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[9]Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[10]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
Tissue: Fetal lung and Fetal spleen.
[11]"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Zhang Z., Henzel W.J.
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 23-37.
[12]"Molecular and functional characterization of a CS1 (CRACC) splice variant expressed in human NK cells that does not contain immunoreceptor tyrosine-based switch motifs."
Lee J.K., Boles K.S., Mathew P.A.
Eur. J. Immunol. 34:2791-2799(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: ALTERNATIVE SPLICING (ISOFORM 3).
[13]"Mouse novel Ly9: a new member of the expanding CD150 (SLAM) family of leukocyte cell-surface receptors."
Tovar V., Del Valle J., Zapater N., Martin M., Romero X., Pizcueta P., Bosch J., Terhorst C., Engel P.
Immunogenetics 54:394-402(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: TISSUE SPECIFICITY, INTERACTION WITH SH2D1A.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF291815 mRNA. Translation: AAK11549.1.
AF390894 mRNA. Translation: AAL26989.1.
AJ271869 mRNA. Translation: CAB76561.1. Frameshift.
AJ276429 mRNA. Translation: CAB81950.2.
AB027233 mRNA. Translation: BAB61022.1.
AY358512 mRNA. Translation: AAQ88876.1.
AK290706 mRNA. Translation: BAF83395.1.
AK298499 mRNA. Translation: BAG60706.1.
AK298548 mRNA. Translation: BAG60745.1.
AK301438 mRNA. Translation: BAG62965.1.
AL834424 mRNA. Translation: CAD39085.1.
AL121985 Genomic DNA. Translation: CAC00579.1.
AL121985 Genomic DNA. Translation: CAH73507.1.
AL121985 Genomic DNA. Translation: CAH73508.1.
CH471121 Genomic DNA. Translation: EAW52704.1.
BC027867 mRNA. Translation: AAH27867.1.
CCDSCCDS1209.1. [Q9NQ25-1]
CCDS60324.1. [Q9NQ25-2]
RefSeqNP_001269517.1. NM_001282588.1. [Q9NQ25-4]
NP_001269519.1. NM_001282590.1. [Q9NQ25-2]
NP_001269521.1. NM_001282592.1. [Q9NQ25-5]
NP_001269524.1. NM_001282595.1.
NP_067004.3. NM_021181.4. [Q9NQ25-1]
UniGeneHs.517265.

3D structure databases

ProteinModelPortalQ9NQ25.
SMRQ9NQ25. Positions 31-216.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid121782. 4 interactions.
IntActQ9NQ25. 3 interactions.
MINTMINT-4722730.
STRING9606.ENSP00000357022.

PTM databases

PhosphoSiteQ9NQ25.

Polymorphism databases

DMDM66774034.

Proteomic databases

MaxQBQ9NQ25.
PaxDbQ9NQ25.
PRIDEQ9NQ25.

Protocols and materials databases

DNASU57823.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000359331; ENSP00000352281; ENSG00000026751.
ENST00000368042; ENSP00000357021; ENSG00000026751. [Q9NQ25-2]
ENST00000368043; ENSP00000357022; ENSG00000026751. [Q9NQ25-1]
ENST00000441662; ENSP00000405605; ENSG00000026751.
ENST00000444090; ENSP00000416592; ENSG00000026751.
ENST00000458602; ENSP00000409965; ENSG00000026751.
GeneID57823.
KEGGhsa:57823.
UCSCuc001fwq.3. human. [Q9NQ25-1]
uc001fws.3. human. [Q9NQ25-2]

Organism-specific databases

CTD57823.
GeneCardsGC01P160709.
HGNCHGNC:21394. SLAMF7.
HPACAB015445.
MIM606625. gene.
neXtProtNX_Q9NQ25.
PharmGKBPA134977110.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG272174.
HOGENOMHOG000013065.
HOVERGENHBG079189.
InParanoidQ9NQ25.
KOK06733.
OMAEDVTYSW.
OrthoDBEOG77HDFC.
PhylomeDBQ9NQ25.
TreeFamTF334964.

Gene expression databases

ArrayExpressQ9NQ25.
BgeeQ9NQ25.
CleanExHS_SLAMF7.
GenevestigatorQ9NQ25.

Family and domain databases

Gene3D2.60.40.10. 1 hit.
InterProIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
IPR015631. SLAM_fam_rcpts.
[Graphical view]
PANTHERPTHR12080. PTHR12080. 1 hit.
PfamPF07686. V-set. 1 hit.
[Graphical view]
SMARTSM00409. IG. 1 hit.
[Graphical view]
PROSITEPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GeneWikiSLAMF7.
GenomeRNAi57823.
NextBio35464059.
PROQ9NQ25.
SOURCESearch...

Entry information

Entry nameSLAF7_HUMAN
AccessionPrimary (citable) accession number: Q9NQ25
Secondary accession number(s): A8K3U1 expand/collapse secondary AC list , B4DPU4, B4DPY3, B4DWA3, Q8N6Y8, Q8ND32, Q9NY08, Q9NY23
Entry history
Integrated into UniProtKB/Swiss-Prot: May 24, 2005
Last sequence update: October 1, 2000
Last modified: July 9, 2014
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 1

Human chromosome 1: entries, gene names and cross-references to MIM

Human cell differentiation molecules

CD nomenclature of surface proteins of human leucocytes and list of entries