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Protein
Submitted name:

PTPRJ, protein tyrosine phosphatase receptor J, eta

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
PTPRJ, protein tyrosine phosphatase receptor J, etaImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA34018.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 35Sequence analysisAdd BLAST35
ChainiPRO_500433566136 – 425Sequence analysisAdd BLAST390

Proteomic databases

MaxQBiQ9NPR5.
PaxDbiQ9NPR5.
PeptideAtlasiQ9NPR5.
PRIDEiQ9NPR5.

Expressioni

Gene expression databases

BgeeiENSG00000149177.
GenevisibleiQ9NPR5. HS.

Interactioni

Protein-protein interaction databases

IntActiQ9NPR5. 1 interactor.
STRINGi9606.ENSP00000400010.

Structurei

3D structure databases

ProteinModelPortaliQ9NPR5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini121 – 209Fibronectin type-IIIInterPro annotationAdd BLAST89
Domaini368 – 425Fibronectin type-IIIInterPro annotationAdd BLAST58

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0791. Eukaryota.
COG5599. LUCA.
HOGENOMiHOG000203312.
HOVERGENiHBG062475.
KOiK05698.

Family and domain databases

CDDicd00063. FN3. 1 hit.
Gene3Di2.60.40.10. 2 hits.
InterProiIPR003961. FN3_dom.
IPR013783. Ig-like_fold.
[Graphical view]
PfamiPF00041. fn3. 1 hit.
[Graphical view]
SMARTiSM00060. FN3. 2 hits.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 2 hits.
PROSITEiPS50853. FN3. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9NPR5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPAAREARL PPRSPGLRWA LPLLLLLLRL GQILCAGGTP SPIPDPSVAT
60 70 80 90 100
VATGENGITQ ISSTAESFHK QNGTGTPQVE TNTSEDGESS GANDSLRTPE
110 120 130 140 150
QGSNGTDGAS QKTPSSTGPS PVFDIKAVSI SPTNVILTWK SNDTAASEYK
160 170 180 190 200
YVVKHKMENE KTITVVHQPW CNITGLRPAT SYVFSITPGI GNETWGDPRV
210 220 230 240 250
IKVITEPIPV SDLRVALTGV RKAALSWSNG NGTASCRVLL ESIGSHEELT
260 270 280 290 300
QDSRLQVNIS GLKPGVQYNI NPYLLQSNKT KGDPLGTEGG LDASNTERSR
310 320 330 340 350
AGSPTAPVHD ESLVGPVDPS SGQQSRDTEV LLVGLEPGTR YNATVYSQAA
360 370 380 390 400
NGTEGQPQAI EFRTNAIQVF DVTAVNISAT SLTLIWKVSD NESSSNYTYK
410 420
IHVAGETDSS NLNVSEPRAV IPGLR
Length:425
Mass (Da):45,078
Last modified:October 1, 2000 - v1
Checksum:iBD1ACA5D345B7027
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei425Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL359057 mRNA. Translation: CAB94390.1.
RefSeqiNP_002834.3. NM_002843.3.
UniGeneiHs.318547.

Genome annotation databases

GeneIDi5795.
KEGGihsa:5795.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL359057 mRNA. Translation: CAB94390.1.
RefSeqiNP_002834.3. NM_002843.3.
UniGeneiHs.318547.

3D structure databases

ProteinModelPortaliQ9NPR5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9NPR5. 1 interactor.
STRINGi9606.ENSP00000400010.

Proteomic databases

MaxQBiQ9NPR5.
PaxDbiQ9NPR5.
PeptideAtlasiQ9NPR5.
PRIDEiQ9NPR5.

Protocols and materials databases

DNASUi5795.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5795.
KEGGihsa:5795.

Organism-specific databases

CTDi5795.
PharmGKBiPA34018.

Phylogenomic databases

eggNOGiKOG0791. Eukaryota.
COG5599. LUCA.
HOGENOMiHOG000203312.
HOVERGENiHBG062475.
KOiK05698.

Miscellaneous databases

GenomeRNAii5795.

Gene expression databases

BgeeiENSG00000149177.
GenevisibleiQ9NPR5. HS.

Family and domain databases

CDDicd00063. FN3. 1 hit.
Gene3Di2.60.40.10. 2 hits.
InterProiIPR003961. FN3_dom.
IPR013783. Ig-like_fold.
[Graphical view]
PfamiPF00041. fn3. 1 hit.
[Graphical view]
SMARTiSM00060. FN3. 2 hits.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 2 hits.
PROSITEiPS50853. FN3. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9NPR5_HUMAN
AccessioniPrimary (citable) accession number: Q9NPR5
Secondary accession number(s): E9PG76
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: November 30, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.