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  1. 1
    "Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide."
    Koenig J., Cui Y., Nies A.T., Keppler D.
    J. Biol. Chem. 275:23161-23168(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1), GLYCOSYLATION.
    Category: PTM / Processing, Sequences.
    Tissue: Liver.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 other entries.

  2. 2
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Category: Sequences.
    Tissue: Liver.
    Source: UniProtKB/Swiss-Prot (reviewed).
  3. 3
    "Molecular identification of LST-3 subtype."
    Mizutamari H., Abe T.
    Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  4. 4
    "The finished DNA sequence of human chromosome 12."
    Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
    , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A.
    Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3861 other entries.

  5. 5
    "Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver."
    van de Steeg E., Stranecky V., Hartmannova H., Noskova L., Hrebicek M., Wagenaar E., van Esch A., de Waart D.R., Oude Elferink R.P., Kenworthy K.E., Sticova E., al-Edreesi M., Knisely A.S., Kmoch S., Jirsa M., Schinkel A.H.
    J. Clin. Invest. 122:519-528(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INVOLVEMENT IN HBLRR.
    Category: Function, Pathology & Biotech.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 23 other entries.

  6. 6
    "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: Sequences.
    Tissue: Liver.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 11205 other entries.

  7. 7
    Category: Pathology & Biotech, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 974 and mapped to 2 other entries.

  8. 8
    "Human organic anion transporting polypeptide 8 promoter is transactivated by the farnesoid X receptor/bile acid receptor."
    Jung D., Podvinec M., Meyer U.A., Mangelsdorf D.J., Fried M., Meier P.J., Kullak-Ublick G.A.
    Gastroenterology 122:1954-1966(2002) [PubMed] [Europe PMC] [Abstract]
    Annotation: Human organic anion transporting polypeptide 8 promoter is transactivated by the farnesoid X receptor/bile acid receptor.Imported.
    Source: GeneRIF:28234.

    This publication is mapped to 5 other entries.

  9. 9
    "The human organic anion transporting polypeptide 8 (SLCO1B3) gene is transcriptionally repressed by hepatocyte nuclear factor 3beta in hepatocellular carcinoma."
    Vavricka S.R., Jung D., Fried M., Grutzner U., Meier P.J., Kullak-Ublick G.A.
    J. Hepatol. 40:212-218(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: HNF3beta represses transcription of the OATP8 but not the OATP-C gene providing a mechanism for reduced expression of OATP8 in hepatocellular carcinomaImported.
    Source: GeneRIF:28234.

    This publication is mapped to 8 other entries.

  10. 10
    "Mutations in the SLCO1B3 gene affecting the substrate specificity of the hepatocellular uptake transporter OATP1B3 (OATP8)."
    Letschert K., Keppler D., Konig J.
    Pharmacogenetics 14:441-452(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: The functional consequences of three polymorphisms and one artificial mutation include differences in the localization and in hepatocellular transport of several OATP1B3 proteins.Imported.
    Source: GeneRIF:28234.

    This publication is mapped to 5 other entries.

  11. 11
    "Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3."
    Yamaguchi H., Okada M., Akitaya S., Ohara H., Mikkaichi T., Ishikawa H., Sato M., Matsuura M., Saga T., Unno M., Abe T., Mano N., Hishinuma T., Goto J.
    J. Lipid Res. 47:1196-1202(2006) [PubMed] [Europe PMC] [Abstract]
    Annotation: OATP1B3 play important roles in CDCA uptake into the liver.Imported.
    Source: GeneRIF:28234.

    This publication is mapped to 14 other entries.

  12. 12
    "Farnesoid X receptor, hepatocyte nuclear factors 1alpha and 3beta are essential for transcriptional activation of the liver-specific organic anion transporter-2 gene."
    Ohtsuka H., Abe T., Onogawa T., Kondo N., Sato T., Oshio H., Mizutamari H., Mikkaichi T., Oikawa M., Rikiyama T., Katayose Y., Unno M.
    J. Gastroenterol. 41:369-377(2006) [PubMed] [Europe PMC] [Abstract]
    Annotation: the transcription of the LST-2 gene is regulated by three transcription factors FXR HNF1alpha and HNF3beta.Imported.
    Source: GeneRIF:28234.

    This publication is mapped to 5 other entries.

  13. 13
    "OATP8/1B3-mediated cotransport of bile acids and glutathione: an export pathway for organic anions from hepatocytes?"
    Briz O., Romero M.R., Martinez-Becerra P., Macias R.I., Perez M.J., Jimenez F., San Martin F.G., Marin J.J.
    J. Biol. Chem. 281:30326-30335(2006) [PubMed] [Europe PMC] [Abstract]
    Annotation: although both OATP-C/1B1 and OATP8/1B3 are highly expressed and able to transport bile acids their mechanisms of action are differentImported.
    Source: GeneRIF:28234.

    This publication is mapped to 5 other entries.

  14. 14
    "Variants in the SLCO1B3 gene: interethnic distribution and association with paclitaxel pharmacokinetics."
    Smith N.F., Marsh S., Scott-Horton T.J., Hamada A., Mielke S., Mross K., Figg W.D., Verweij J., McLeod H.L., Sparreboom A.
    Clin. Pharmacol. Ther. 81:76-82(2007) [PubMed] [Europe PMC] [Abstract]
    Annotation: Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)Imported.
    Source: GeneRIF:28234.

    This publication is mapped to 5 other entries.

  15. 15
    "Human organic anion transporter 1B1 and 1B3 function as bidirectional carriers and do not mediate GSH-bile acid cotransport."
    Mahagita C., Grassl S.M., Piyachaturawat P., Ballatori N.
    Am. J. Physiol. Gastrointest. Liver Physiol. 293:G271-8(2007) [PubMed] [Europe PMC] [Abstract]
    Annotation: these results indicate that OATP1B3/OATP-8 and OATP1B1/OATP-C most likely function as bidirectional facilitated diffusion transporters and that GSH is not a substrate or activator of their transport activity.Imported.
    Source: GeneRIF:28234.

    This publication is mapped to 14 other entries.

  16. 16
    "Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil."
    Treiber A., Schneiter R., Hausler S., Stieger B.
    Drug Metab. Dispos. 35:1400-1407(2007) [PubMed] [Europe PMC] [Abstract]
    Annotation: Bosentan uptake into Chinese hamster ovary cells expressing human OATP1B1 or OATP1B3 and was efficiently inhibited by cyclosporin A rifampicin and to a lesser extent by sildenafil.Imported.
    Source: GeneRIF:28234.

    This publication is mapped to 14 other entries.

  17. 17
    "Human liver-specific organic anion transporter-2 is a potent prognostic factor for human breast carcinoma."
    Muto M., Onogawa T., Suzuki T., Ishida T., Rikiyama T., Katayose Y., Ohuchi N., Sasano H., Abe T., Unno M.
    Cancer Sci. 98:1570-1576(2007) [PubMed] [Europe PMC] [Abstract]
    Annotation: LST-2 overexpression is associated with a hormone-dependent growth mechanism of the breast cancerImported.
    Source: GeneRIF:28234.

    This publication is mapped to 5 other entries.

  18. 18
    "Influence of SLCO1B1, 1B3, 2B1 and ABCC2 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients."
    Miura M., Satoh S., Inoue K., Kagaya H., Saito M., Inoue T., Suzuki T., Habuchi T.
    Eur. J. Clin. Pharmacol. 63:1161-1169(2007) [PubMed] [Europe PMC] [Abstract]
    Annotation: Observational study of gene-disease association gene-gene interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)Imported.
    Source: GeneRIF:28234.

    This publication is mapped to 25 other entries.

  19. 19
    "Rapid screening of antineoplastic candidates for the human organic anion transporter OATP1B3 substrates using fluorescent probes."
    Yamaguchi H., Kobayashi M., Okada M., Takeuchi T., Unno M., Abe T., Goto J., Hishinuma T., Mano N.
    Cancer Lett. 260:163-169(2008) [PubMed] [Europe PMC] [Abstract]
    Annotation: Performed transport assays in OATP1B3-expressing cells as a method of indentifying novel antineoplastic agents.Imported.
    Source: GeneRIF:28234.

    This publication is mapped to 5 other entries.

  20. 20
    "Establishment of a set of double transfectants coexpressing organic anion transporting polypeptide 1B3 and hepatic efflux transporters for the characterization of the hepatobiliary transport of telmisartan acylglucuronide."
    Ishiguro N., Maeda K., Saito A., Kishimoto W., Matsushima S., Ebner T., Roth W., Igarashi T., Sugiyama Y.
    Drug Metab. Dispos. 36:796-805(2008) [PubMed] [Europe PMC] [Abstract]
    Annotation: A set of double transfectants expressing OATP1B3 combined with OAT1B1 can be used as a tool for rapid identification of hepatic uptake and efflux transporters of many organic anions that are substrates of OATP1B1 or OATP1B3.Imported.
    Source: GeneRIF:28234.

    This publication is mapped to 14 other entries.

  21. 21
    "Association of genetic polymorphisms in SLCO1B3 and ABCC2 with docetaxel-induced leukopenia."
    Kiyotani K., Mushiroda T., Kubo M., Zembutsu H., Sugiyama Y., Nakamura Y.
    Cancer Sci. 99:967-972(2008) [PubMed] [Europe PMC] [Abstract]
    Annotation: Observational study of gene-disease association gene-gene interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator); SNPs in and SLCO1B3 may predict the risk of leukopenia/neutropenia induced by docetaxel chemotherapy.Imported.
    Source: GeneRIF:28234.

    This publication is mapped to 43 other entries.

  22. 22
    "Interaction of oral antidiabetic drugs with hepatic uptake transporters: focus on organic anion transporting polypeptides and organic cation transporter 1."
    Bachmakov I., Glaeser H., Fromm M.F., Konig J.
    Diabetes 57:1463-1469(2008) [PubMed] [Europe PMC] [Abstract]
    Annotation: Alterations of OATP1BB3 function by oral antidiabetic drugs have to be considered as potential mechanisms underlying drug-drug interactions.Imported.
    Source: GeneRIF:28234.

    This publication is mapped to 14 other entries.

  23. 23
    "Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3."
    Gui C., Miao Y., Thompson L., Wahlgren B., Mock M., Stieger B., Hagenbuch B.
    Eur. J. Pharmacol. 584:57-65(2008) [PubMed] [Europe PMC] [Abstract]
    Annotation: Pregnane X receptor ligands by inhibiting or stimulating OATP1B3-mediated uptake can lead to drug-drug interactions at the transporter level.Imported.
    Source: GeneRIF:28234.

    This publication is mapped to 14 other entries.

  24. 24
    Category: Pathology & Biotech.
    Annotation: Associated with DEVELOPMENTAL: height.Imported.
    Source: GAD:599684.

    This publication is mapped to 750 other entries.

  25. 25
    "Pharmacogenetic pathway analysis of docetaxel elimination."
    Baker S.D., Verweij J., Cusatis G.A., van Schaik R.H., Marsh S., Orwick S.J., Franke R.M., Hu S., Schuetz E.G., Lamba V., Messersmith W.A., Wolff A.C., Carducci M.A., Sparreboom A.
    Clin. Pharmacol. Ther. 85:155-163(2009) [PubMed] [Europe PMC] [Abstract]
    Annotation: Observational study of gene-disease association gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)Imported.
    Source: GeneRIF:28234.

    This publication is mapped to 22 other entries.

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