Q9NP10 (Q9NP10_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
IGF1 protein EMBL AAA52543.1

Gene names

Name:

IGF1 EMBL AAA52543.1

Organism

Homo sapiens (Human) EMBL AAA52543.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	130 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Secreted By similarity RuleBase RU000406.
Sequence similarities	Belongs to the insulin family. RuleBase RU000406

Ontologies

Keywords
Cellular component	Secreted SAAS SAAS022353
Domain	Signal EMBL AAA52543.1
Gene Ontology (GO)
Cellular component	extracellular space Inferred from electronic annotation. Source: InterPro
Molecular function	growth factor activity Inferred from electronic annotation. Source: InterPro hormone activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 25	25	Potential EMBL AAA52543.1
	Chain	26 – 130	105	Potential EMBL AAA52543.1		PRO_5000143246
	Chain	26 – 95	70	Potential EMBL AAA52543.1		PRO_5000143247

Sequences

	Sequence		Length	Mass (Da)
	Q9NP10 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 970FBAAECFA0352D	FASTA	130	14,407
	10 20 30 40 50 60 MHTMSSSHLF YLALCLLTFT SSATAGPETL CGAELVDALQ FVCGDRGFYF NKPTGYGSSS 70 80 90 100 110 120 RRAPQTGIVD ECCFRSCDLR RLEMYCAPLK PAKSARSVRA QRHTDMPKTQ KEVHLKNASR 130 GSAGNKNYRM

References

[1]	"Human insulin-like growth factor I and II messenger RNA: isolation of complementary DNA and analysis of expression." Rall L.B., Scott J., Bell G.I. Methods Enzymol. 146:239-248(1987) [PubMed: 3683205] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M29644 mRNA. Translation: AAA52543.1.
IPI	IPI00793994.
UniGene	Hs.160562.
3D structure databases
HSSP	HSSP built from PDB template 2GF1 based on UniProtKB P01343.
ProteinModelPortal	Q9NP10.
SMR	Q9NP10. Positions 26-95.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9NP10.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
UCSC	uc001tjn.2. human.
Phylogenomic databases
GeneTree	ENSGT00530000063856.
HOVERGEN	HBG006137.
Gene expression databases
ArrayExpress	Q9NP10.
Bgee	Q9NP10.
Family and domain databases
InterPro	IPR022341. IGF-I. IPR016179. Insulin-like. IPR022350. Insulin-like_growth_factor. IPR022353. Insulin_CS. IPR022352. Insulin_family. [Graphical view]
Gene3D	G3DSA:1.10.100.10. Ins/IGF/relaxin. 1 hit.
Pfam	PF00049. Insulin. 2 hits. [Graphical view]
PRINTS	PR02002. INSLNLIKEGF. PR02005. INSLNLIKEGF1. PR00276. INSULINFAMLY.
SMART	SM00078. IlGF. 1 hit. [Graphical view]
SUPFAM	SSF56994. Insulin-like. 1 hit.
PROSITE	PS00262. INSULIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9NP10_HUMAN

Accession

Primary (citable) accession number: Q9NP10

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	January 25, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.